• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
* * * * - 3 votes

Healing the mind from DXM-induced psychosis


  • Please log in to reply
208 replies to this topic

#121 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 27 November 2010 - 11:22 PM

Bump again...anyone?

#122 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 27 November 2010 - 11:23 PM

To moderator: double post, please delete

Edited by Spectre, 27 November 2010 - 11:54 PM.


sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#123 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 27 November 2010 - 11:25 PM

To moderator: double post, please delete

Edited by Spectre, 27 November 2010 - 11:54 PM.


#124 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 28 November 2010 - 02:03 AM

Meditation , Chanting and allot of time (healing takes time) Stay strong and remember like the Dalia Lama says NEVER GIVE UP!
http://www.slideshar...s-chanting-work

#125 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 29 November 2010 - 06:32 AM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.

#126 Haddaway

  • Guest
  • 1 posts
  • 0
  • Location:Lake Wortth, FL

Posted 29 November 2010 - 06:24 PM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.

Can you please expound on what supplements you think helped you the most with short-term memory recall and retention? Also in terms of concentration and focus. I've read this entire thread and have seen you have experimented with a multitude of supplements. What do you think would be worth taking for me in terms of the aforementioned benefits above? I really need this as I have been extremely depressed, and felt like my cognitive abilities have declined, especially in the memory department. I too have abused DXM, but at a much higher frequency than you have stated (but I do not believe it caused any long term negative effects in me, but hey you never know really)

I would greatly, greatly appreciate what supplements you could recommend for me? My thinking has been very cloudy, and not very fluid. (sometimes forget what I'm saying in the middle of explaining a thought, or forget simple words or memories that I never did before) I am on medication that might be making it worse, so I am tapering off of those.

Any help would be so greatly appreciated.

(obviously every person is different, but I would like somewhere to start)

Edited by Haddaway, 29 November 2010 - 06:25 PM.


#127 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 30 November 2010 - 07:53 AM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.

Can you please expound on what supplements you think helped you the most with short-term memory recall and retention? Also in terms of concentration and focus. I've read this entire thread and have seen you have experimented with a multitude of supplements. What do you think would be worth taking for me in terms of the aforementioned benefits above? I really need this as I have been extremely depressed, and felt like my cognitive abilities have declined, especially in the memory department. I too have abused DXM, but at a much higher frequency than you have stated (but I do not believe it caused any long term negative effects in me, but hey you never know really)

I would greatly, greatly appreciate what supplements you could recommend for me? My thinking has been very cloudy, and not very fluid. (sometimes forget what I'm saying in the middle of explaining a thought, or forget simple words or memories that I never did before) I am on medication that might be making it worse, so I am tapering off of those.

Any help would be so greatly appreciated.

(obviously every person is different, but I would like somewhere to start)


I'm sorry to hear about your situation, I know it too well myself..I would recommend fish oil, piracetam (with alpha-gpc as a choline source), and SAMe to start off..this should help with some of your depression and cognitive declination. I'm still suffering from this psychosis and I would do anything to just be normal again..but taking the supplements I listed above have really helped me out personally. If you respond well to those, let me know and I will give you my further personal recommendations (keep in mind I'm not a doctor and all of this is just my opinion from personal experience).

I read that DXM can cause temporal lobe epilepsy, which can cause a lot of deja vu resulting from simple partial seizures..does anyone have knowledge about this mental disorder and if it can be cured completely? (This was completely drug induced, it wasn't something I dealt with before the drug use). I believe the Salvia Divinorum and the dextromethorphan both triggered TLE in my brain, and I have since then been suffering from it..I am more than convinced that that's the source of my deja vu and psychosis. Should I be taking anti-epileptics or benzodiazepines to deal with the TLE? I'm just so tired of driving myself crazy over this..thanks in advance.

Edited by Spectre, 30 November 2010 - 07:53 AM.


#128 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 30 November 2010 - 07:56 AM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.

Can you please expound on what supplements you think helped you the most with short-term memory recall and retention? Also in terms of concentration and focus. I've read this entire thread and have seen you have experimented with a multitude of supplements. What do you think would be worth taking for me in terms of the aforementioned benefits above? I really need this as I have been extremely depressed, and felt like my cognitive abilities have declined, especially in the memory department. I too have abused DXM, but at a much higher frequency than you have stated (but I do not believe it caused any long term negative effects in me, but hey you never know really)

I would greatly, greatly appreciate what supplements you could recommend for me? My thinking has been very cloudy, and not very fluid. (sometimes forget what I'm saying in the middle of explaining a thought, or forget simple words or memories that I never did before) I am on medication that might be making it worse, so I am tapering off of those.

Any help would be so greatly appreciated.

(obviously every person is different, but I would like somewhere to start)


I'm sorry to hear about your situation, I know it too well myself..I would recommend fish oil, piracetam (with alpha-gpc as a choline source), and SAMe to start off..this should help with some of your depression and cognitive declination. I'm still suffering from this psychosis and I would do anything to just be normal again..but taking the supplements I listed above have really helped me out personally. If you respond well to those, let me know and I will give you my further personal recommendations (keep in mind I'm not a doctor and all of this is just my opinion from personal experience).

I read that DXM can cause temporal lobe epilepsy, which can cause a lot of deja vu resulting from simple partial seizures..does anyone have knowledge about this mental disorder and if it can be cured completely? (This was completely drug induced, it wasn't something I dealt with before the drug use). I believe the Salvia Divinorum and the dextromethorphan both triggered TLE in my brain, and I have since then been suffering from it..I am more than convinced that that's the source of my deja vu and psychosis. Should I be taking anti-epileptics or benzodiazepines to deal with the TLE? I'm just so tired of driving myself crazy over this..thanks in advance.




After getting two sitters and a way to be restrained, take 8.6 grams of magic mushrooms and go to sleep. You may be fixed in the morning for at least 4-6 months.

Edited by Ark, 30 November 2010 - 07:57 AM.


#129 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 30 November 2010 - 06:18 PM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.

Can you please expound on what supplements you think helped you the most with short-term memory recall and retention? Also in terms of concentration and focus. I've read this entire thread and have seen you have experimented with a multitude of supplements. What do you think would be worth taking for me in terms of the aforementioned benefits above? I really need this as I have been extremely depressed, and felt like my cognitive abilities have declined, especially in the memory department. I too have abused DXM, but at a much higher frequency than you have stated (but I do not believe it caused any long term negative effects in me, but hey you never know really)

I would greatly, greatly appreciate what supplements you could recommend for me? My thinking has been very cloudy, and not very fluid. (sometimes forget what I'm saying in the middle of explaining a thought, or forget simple words or memories that I never did before) I am on medication that might be making it worse, so I am tapering off of those.

Any help would be so greatly appreciated.

(obviously every person is different, but I would like somewhere to start)


I'm sorry to hear about your situation, I know it too well myself..I would recommend fish oil, piracetam (with alpha-gpc as a choline source), and SAMe to start off..this should help with some of your depression and cognitive declination. I'm still suffering from this psychosis and I would do anything to just be normal again..but taking the supplements I listed above have really helped me out personally. If you respond well to those, let me know and I will give you my further personal recommendations (keep in mind I'm not a doctor and all of this is just my opinion from personal experience).

I read that DXM can cause temporal lobe epilepsy, which can cause a lot of deja vu resulting from simple partial seizures..does anyone have knowledge about this mental disorder and if it can be cured completely? (This was completely drug induced, it wasn't something I dealt with before the drug use). I believe the Salvia Divinorum and the dextromethorphan both triggered TLE in my brain, and I have since then been suffering from it..I am more than convinced that that's the source of my deja vu and psychosis. Should I be taking anti-epileptics or benzodiazepines to deal with the TLE? I'm just so tired of driving myself crazy over this..thanks in advance.




After getting two sitters and a way to be restrained, take 8.6 grams of magic mushrooms and go to sleep. You may be fixed in the morning for at least 4-6 months.


Serious?..I haven't eaten mushrooms for about a year and a half, and it does a good job at alleviating my OCD, I never thought about using it for my memory disruptions..how would psilocybin affect TLE? And I've never tried sleeping on them, I don't even know how that would be possible lol.

Edited by Spectre, 30 November 2010 - 06:18 PM.


#130 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 03 December 2010 - 05:34 AM

Bump...

How would psilocybin temporarily cure symptoms of TLE?

#131 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 10 December 2010 - 09:14 AM

Bump...

#132 Mindweaver

  • Guest
  • 109 posts
  • -1

Posted 11 December 2010 - 04:41 PM

I'm pretty sure the guy who was talking about shrooms was just fucking with u. Spectre, I'm telling you, the best way to go about healing is:

Take piracetam
Eat healthy/Exercise
Take walks in the sun and be very speculative of your surroundings
Stop visiting a forum about it, as this leads to chronic subconscious thought, which probably has worsened. Out of sight, out of mind, this is important...
  • dislike x 1
  • like x 1

#133 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 11 December 2010 - 04:51 PM

I'm pretty sure the guy who was talking about shrooms was just fucking with u. Spectre, I'm telling you, the best way to go about healing is:

Take piracetam
Eat healthy/Exercise
Take walks in the sun and be very speculative of your surroundings
Stop visiting a forum about it, as this leads to chronic subconscious thought, which probably has worsened. Out of sight, out of mind, this is important...

Hi there, there's a lot of emerging evidence supporting the potential use of 5ht2a receptor agonists as a form of treatment for his type of disorder.

Psilocybin the active compound in "magic mushrooms" is at the forefront of this research with very promi)sing results coming from the first FDA approved trial in over 25 years.
http://wiki.dmt-nexu...bin_and_OCD.pdf

This is all and well but who knows when such a substance will be developed for use in the wider population.

So it got me thinking surely the role of 5ht2a agonists in medicine has been explored before and it turns out it has:
http://en.wikipedia....ethyltryptamine

I think you should research

Edited by Ark, 11 December 2010 - 04:52 PM.


#134 Mindweaver

  • Guest
  • 109 posts
  • -1

Posted 11 December 2010 - 05:22 PM

Only reason I stated bullshit was that you posted it, and then never responded to his subsequent 'bumps.' I've experimented 3x with psilocybin, 2x MDMA and 1x LSD after chemically inducing depersonalization with DXM, and I think the best afterglow was with LSD and MDMA (LSD's color/edge definition is still lasting to this day and it has been +1 month).
  • dislike x 1
  • like x 1

#135 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 18 December 2010 - 09:30 AM

Bump..

Does anyone on here think that my condition is perhaps an atypical form of HPPD? I just did some reading on it and have considered it a possibility, but I can't verify it (I went to the doctor today but he wanted to put me on 3 different medications, including tegretol, wellbutrin, and ambien..I declined the tegretol after reading up on the adverse effects associated with the medication). I haven't taken any of it yet as I won't be able to pick it up until next week..anyway, I don't see how any of those medications could possibly help my situation at all..so I'll have to take it upon myself to find a decent medication to help with my condition.

If my condition is perhaps HPPD (I do get strange visual effects every now and then..ie: I'll see a strange dot for a split second in my field of view in a random place that's completely off-color with anything around it..sort of how a dead pixel on a monitor looks like, but only for about half a second, it occurs once every other day or so noticeably), are there any known cures or medications that can fix the abnormalities? I'm still looking at deprenyl as a potential therapy, it's gotten a lot of good feedback and I think it would also help with the huge amount of depression I've been dealing with lately..unfortunately for me, my doctor never even heard of the drug before so I couldn't get a prescription to it. Here is some information on HPPD that I found from wiki that convinced me that this may be what I potentially have. (I have all the co-existing conditions).

Causes

The cause(s) of HPPD are not yet known. The most current neurological research indicates that HPPD symptoms may manifest from abnormalities in CNS function, following the hallucinogen use.[3][4][5] One theory derived from this research is that inhibitory mechanisms involved with sensory gating are disrupted.[6]
In some cases, HPPD appears to have a sudden onset after a single drug experience, strongly suggesting the drug played a direct role in triggering symptoms. But in other cases, people report gradual worsening of symptoms with ongoing drug use. Drugs that have been associated with HPPD include LSD,[1] 2C-I, 5-MeO-DIPT,[7] MDMA,[8][9] Psilocybin,[10] Mescaline,[1] diphenhydramine, mephedrone, PCP, and high doses of dextromethorphan, and ambien. In long term use or abuse adderall has also been indicated, although some suggest with only visual disturbances.

Co-existing problems

The visual problems of HPPD can occur along with other mental ailments. Of these, the most prominent are anxiety, panic attacks, depersonalization disorder, and depression. In the sample of Baggott and colleagues, hallucinogen users with persisting and severe visual problems were significantly more likely to report anxiety and depression diagnoses than hallucinogen users without serious visual problems. For example, 25.9% of hallucinogen users with visual problems reported current or past diagnosis of depression. While it is difficult, if not impossible, to establish a clear relationship between the visual and mental symptoms, those with HPPD often testify that a connection indeed exists. For example, anxiety can cause the visuals to become more prominent and vice-versa. Anecdotal wisdom thus maintains that there is a synergistic link between the two. However, there appear to be people with 'pure' cases of HPPD in which no other disorders co-exist.


Any feedback and advice is greatly appreciated, thank you.

Edited by Spectre, 18 December 2010 - 09:36 AM.


#136 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 19 December 2010 - 06:15 AM

Bump again

#137 OneScrewLoose

  • Guest
  • 2,378 posts
  • 51
  • Location:California
  • NO

Posted 28 December 2010 - 08:26 AM

I recently took DXM, so I have a story to tell you that may help.

I've had panic attacks all my life, and they stayed with me at all times, even though I was so used to them that I didn't even call them panic attacks until recently. Everything changed when I went on Lamictal. The anxiety went away, but so did a good portion of my memory, emotional sensation, and ability to learn. After being on it for a year, I slowly went off. Some of my memory came back, but not all of it, and I was still numb, but I wasn't having the panic attacks.

That numbness eventually got to me, and I became desperate to try things I normally wouldn't, one of which was DXM. A month ago, I ended up taking 285mg of DXM within a two hour timespan. Another hour or two in, and I all of a sudden got waves of panic attacks. I beat them back each time by just "letting go" of it (this was the thought process in my head). As I came down from it, I had a wonderful experience; I had real feelings for the first time since I took the Lamictal. Unfortunately for me, I didn't realize what was happening. It undid ALL of the effects of the Lamictal, include the end of my panic attacks, which started getting worse, and worse, and worse. Recognizing what was happening, I went back on the Lamictal thanks to an old prescription lying around. Now I am slowly building it up and have to go through this process all over again.

I tell this story because I am wondering if Lamictal will help you. It seems to do the direct opposite of what the DXM does, and may help you in your brain repair. PM me if you need a site from where you can order it from, but it shouldn't be too hard to find.

P.S. I did not read your whole thread, so I don't know what else you are on right now (post your regimen?), so I don't know if it will interact with anything you are taking, so you might want to do some research. Also note that Lamictal has to be built up real slowly, because of a possible rash you could get that is eventually deadly. Do some research before trying.

#138 OneScrewLoose

  • Guest
  • 2,378 posts
  • 51
  • Location:California
  • NO

Posted 10 January 2011 - 01:53 AM

Just curious, has anyone tried acupuncture for any of the DXM related problems discussed on here?

#139 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 12 January 2011 - 11:03 AM

Thank you for your insightful post, I've personally never used lamictal and I would feel very apprehensive about it due to the potentially dangerous side effects associated with the drug..once I do some further research on it my opinion may change.

My current stack:

AM:
- 2.4g fish oil
- 1g piracetam
- 4000iu vitamin D
- 150mg wellbutrin (morning and afternoon)

PM:
- 10mg ambien

I know the stack is weak and I don't have a choline source at the moment, but my budget is low and I need to find the best possible prices available.

#140 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 12 January 2011 - 08:18 PM

So has anything worked for you>? 7 pages and nothing doing the trick for you?

You may need further help then can be provided here, what kind of specialist have you visisted.

#141 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 18 January 2011 - 06:11 PM

So has anything worked for you>? 7 pages and nothing doing the trick for you?

You may need further help then can be provided here, what kind of specialist have you visisted.


Nothing up to this point has really made any substantial effects..until recently. Just a few days ago I got a bottle of Selegiline and started taking it for my first time, and it's already been showing me some promise in helping me with my situation. It's helping me focus better, helps with depression, and is noticeably increasing my overall brain function. I'm currently taking it at 5mg/day, and stacking it with 120mg of Ginkgo Biloba. I haven't taken Piracetam in a few weeks as I've been on vacation and had no intention on bringing it with me to the airport. I've also been taking Wellbutrin (a generic form), at 150mg/day, and although I've seen some warnings of contradiction while combining Wellbutrin and Deprenyl, I haven't noticed any negative effects whatsoever. I may start taking Piracetam and/or Aniracetam again as well, I just want to see the effects from continuing my current regimen, so far, I think it's showing some promise in alleviating my memory/cognitive impairment. I will report on this again soon. (Any recommendations regarding my regimen?) Thank you.

#142 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 18 January 2011 - 06:29 PM

So has anything worked for you>? 7 pages and nothing doing the trick for you?

You may need further help then can be provided here, what kind of specialist have you visisted.


Nothing up to this point has really made any substantial effects..until recently. Just a few days ago I got a bottle of Selegiline and started taking it for my first time, and it's already been showing me some promise in helping me with my situation. It's helping me focus better, helps with depression, and is noticeably increasing my overall brain function. I'm currently taking it at 5mg/day, and stacking it with 120mg of Ginkgo Biloba. I haven't taken Piracetam in a few weeks as I've been on vacation and had no intention on bringing it with me to the airport. I've also been taking Wellbutrin (a generic form), at 150mg/day, and although I've seen some warnings of contradiction while combining Wellbutrin and Deprenyl, I haven't noticed any negative effects whatsoever. I may start taking Piracetam and/or Aniracetam again as well, I just want to see the effects from continuing my current regimen, so far, I think it's showing some promise in alleviating my memory/cognitive impairment. I will report on this again soon. (Any recommendations regarding my regimen?) Thank you.



Yeah actually


Stablon
Naridal(watch for interactions)
Noopet
L thenine
Ashawanga
Bacopa
Picamilon

good luck

Lithum
  • like x 1

#143 kikai93

  • Guest
  • 244 posts
  • 90

Posted 18 January 2011 - 06:38 PM

I will definitely have to start meditation again.

Does anyone have any knowledge of the plant Calea zacatechichi (aka the "dream herb"), and if it can cause deja vu in people? Thanks.


It will do exactly what it says: give you interesting and elaborate dreams. Some people say it also improves dream recall. I can cause deja vu in some people.
It is a mild dissociative, so probably exactly the opposite of what you want.

Edited by kikai93, 18 January 2011 - 06:38 PM.


#144 OneScrewLoose

  • Guest
  • 2,378 posts
  • 51
  • Location:California
  • NO

Posted 20 January 2011 - 08:51 PM

The Lamictal rash thing is very rare, and it doesn't happen suddenly, but rather builds up, so you can get off it at the first sign. I'm back on it though and it's not working the same way as the first time around, I feel like my life is falling apart. This is the dumbest thing I've ever done, and it was only 285mg with in the span of a few hours one single time.

The Lamictal might work for you though, I would try it.

#145 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 23 January 2011 - 03:34 PM

Bump..

Does anyone know if Wellbutrin, Deprenyl, or the combination of the two is linked with tardive dyskinesia? I've been experiencing some strange neck spasms and feel forced to constantly move/stretch it at times..I'm not sure which drug it's attributed to but I'm very concerned about this.

#146 Ark

  • Guest
  • 1,729 posts
  • 383
  • Location:Beijing China

Posted 23 January 2011 - 11:55 PM

Bump..

Does anyone know if Wellbutrin, Deprenyl, or the combination of the two is linked with tardive dyskinesia? I've been experiencing some strange neck spasms and feel forced to constantly move/stretch it at times..I'm not sure which drug it's attributed to but I'm very concerned about this.




Have you tried Cannibis for realiving some of your problems?

#147 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 24 January 2011 - 05:43 PM

Bump..

Does anyone know if Wellbutrin, Deprenyl, or the combination of the two is linked with tardive dyskinesia? I've been experiencing some strange neck spasms and feel forced to constantly move/stretch it at times..I'm not sure which drug it's attributed to but I'm very concerned about this.




Have you tried Cannibis for realiving some of your problems?


I haven't smoked pot in nearly 2 years, mainly for legal purposes and memory impairment.

#148 Spectre

  • Topic Starter
  • Guest
  • 208 posts
  • 58
  • Location:USA

Posted 02 February 2011 - 09:07 AM

Bump..

Is anyone aware of herbs or medicines/drugs that help restore proper memory consolidation and encoding in the brain? That's what my real problem is. I've narrowed down the cause of the disrupted memory consolidation to 3 possible reasons.

1. Kappa Opioid receptor agonism (which is attributed to both dextromethorphan and salvinorin a)
2. Dopamine D2 receptor agonism
3. NMDA receptor disruption

I'm leaning more towards the first two potential reasons at this point. I know Piracetam is an NMDA receptor modulator, and it's helped to a small extent, but it definitely hasn't fixed all my issues otherwise I wouldn't keep posting about this. The recent inclusion of Deprenyl seems to help to a minor degree as well, but it could just be helping with my overall focus and attention, not actually altering the way my brain encodes memories..I believe the negative drug use I did years ago from the DXM and Salvia caused a semi-permanent re-circuiting of my brain which has led to an impairment to how I perceive and consolidate memory formation. (For example, I can think about something I did just a few seconds ago, and have the feeling as if I experienced it years ago, even though it just happened).

The way my brain forms memories is impaired but I don't know of a single other person that has the same issue that I'm dealing with..I think the extensive deja vu I had experienced right after using the drugs was just the maximal effect of this disrupted memory formation in the brain, and it's tapered off to a degree since then obviously..but I think as time went on, the natural plasticity of my brain caused a disrupted restructuring to take place. I went to a psychiatrist today and he was trying to prescribe me to tegretol (?!), my mistake for telling him about being diagnosed with manic depression when I was a child (which in my opinion was misdiagnosed and purely attributed to my environment at the time..anyway), and he didn't seem too educated on the nootropics I was talking to him about (I've given up hope when it comes to seeking "professional" help..I would like to see a neurologist that specializes in this but $$$ is an issue for me right now).

Does anyone have experience with Ashwagandha? From what I read, it helps with memory and could potentially be what I need..I just don't know how effective it is in restoring proper brain function. Any advice is greatly appreciated, thank you.

Edited by Spectre, 02 February 2011 - 09:09 AM.


#149 bobman

  • Guest
  • 258 posts
  • 5

Posted 02 February 2011 - 07:16 PM

Bump..

Is anyone aware of herbs or medicines/drugs that help restore proper memory consolidation and encoding in the brain? That's what my real problem is. I've narrowed down the cause of the disrupted memory consolidation to 3 possible reasons.

1. Kappa Opioid receptor agonism (which is attributed to both dextromethorphan and salvinorin a)
2. Dopamine D2 receptor agonism
3. NMDA receptor disruption

I'm leaning more towards the first two potential reasons at this point. I know Piracetam is an NMDA receptor modulator, and it's helped to a small extent, but it definitely hasn't fixed all my issues otherwise I wouldn't keep posting about this. The recent inclusion of Deprenyl seems to help to a minor degree as well, but it could just be helping with my overall focus and attention, not actually altering the way my brain encodes memories..I believe the negative drug use I did years ago from the DXM and Salvia caused a semi-permanent re-circuiting of my brain which has led to an impairment to how I perceive and consolidate memory formation. (For example, I can think about something I did just a few seconds ago, and have the feeling as if I experienced it years ago, even though it just happened).

The way my brain forms memories is impaired but I don't know of a single other person that has the same issue that I'm dealing with..I think the extensive deja vu I had experienced right after using the drugs was just the maximal effect of this disrupted memory formation in the brain, and it's tapered off to a degree since then obviously..but I think as time went on, the natural plasticity of my brain caused a disrupted restructuring to take place. I went to a psychiatrist today and he was trying to prescribe me to tegretol (?!), my mistake for telling him about being diagnosed with manic depression when I was a child (which in my opinion was misdiagnosed and purely attributed to my environment at the time..anyway), and he didn't seem too educated on the nootropics I was talking to him about (I've given up hope when it comes to seeking "professional" help..I would like to see a neurologist that specializes in this but $$$ is an issue for me right now).

Does anyone have experience with Ashwagandha? From what I read, it helps with memory and could potentially be what I need..I just don't know how effective it is in restoring proper brain function. Any advice is greatly appreciated, thank you.


I have this problem as well. What helped me was a 4 week course of 300mg 2xday of sulbutiamine. Although from what I understand this could lead to disrupted dopamine signalling, ala Animal's theory, and I did notice a period of mild depression after the 4 weeks of use, although that has completely resolved. The use definitely helped (the effect remains, 2 months later) my time sense and long term memory, although I still experience problems with both. My working memory is extremely good, but my long term memory sucks, makes classwork difficult. I do notice that over time my long term memory improves, regardless of medical intervention. I've been off lamictal (actually I was taking an AD & neurontin as well, the latter for anxiety caused by lamictal) for 2 years now (2 years in 2 weeks), and my brain has definitely suffered from the use. Lamictal seems to primarily affect post-synaptic AMPA activity, reducing glutamate release causing a pre-synaptic inhibitory effect on NMDAR's (though I've also read papers theorizing a primarily effect on NA+ and CA2+ ion channels, causing increased open channel time, reducing refractory depolarizations), also upregulates D2 & GABAR's, both of which can disrupt LTP. Not sure how that compares to DXM.

Good luck.

sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#150 dlima

  • Guest
  • 7 posts
  • 1
  • Location:Socorro, NM

Posted 07 February 2011 - 07:15 AM

I'm not sure what country you live in, but have you tried to....eat a few seeds or a length of cactus in order to take a few steps backward, a few to the side, and then a few forward?
That or see a therapist?

DXM was pretty intense for me, I thought it may have had altered my marijuana "high" but in retrospect that could have been my brain's acquired "high" after months of smoking - something I've found to be quite common. A sub-"drunken" dose of DXM definitely synergized with an ever-so-light hit of the diviner's sage, a hit which would normally barely get one laughy, and that 40-sec/40-year trip had persisting effects - for about a week.

...is it bad that I look back on those silly days as though they were childish pursuits... yet I'm only 20 years old? I'm amazed at what change any one year can bring, and I'm very excited to see how the rest of 2011 pans out!




3 user(s) are reading this topic

0 members, 3 guests, 0 anonymous users