I've heard about 20 different things from 50 different people about which supplements are best for dealing with/modulating the symptoms of tinnitus. Everything from anti-oxidants, zinc, ginko biloba. Listening to it all is liable to make my tinnitus worse. So what's the real deal? What supplements and at what doses have been proven to obliterate this problem?

Supplements for tinnitus
#1
Posted 22 July 2011 - 03:20 PM
I've heard about 20 different things from 50 different people about which supplements are best for dealing with/modulating the symptoms of tinnitus. Everything from anti-oxidants, zinc, ginko biloba. Listening to it all is liable to make my tinnitus worse. So what's the real deal? What supplements and at what doses have been proven to obliterate this problem?
#2
Posted 22 July 2011 - 06:58 PM
#3
Posted 22 July 2011 - 10:17 PM
#4
Posted 22 July 2011 - 11:35 PM
#5
Posted 24 July 2011 - 11:12 AM
#6
Posted 24 July 2011 - 03:26 PM
Funny thing is that i found this out because I noticed my tinnitus got less severe when I took a couple red bulls. I found out its likely the taurine causing this;
http://www.ncbi.nlm....pubmed/20868734
But by far the most important thing for tinnitus, at least in my case, is bringing your stress down.
#7
Posted 24 July 2011 - 03:29 PM
http://www.swansonvi...s-symptoms.html
Although when I took pycnogenol, my tinnitus was probably worse than when I wasn't taking it.
I believe there are some studies using ginko biloba too. And citrus bioflavanoids were studied, as well (although it's a very iffy study).
Best bet is probably to see an ENT first. As mentioned above, there could be a couple of different causes. Even certain medicines can cause it.
Edited by nameless, 24 July 2011 - 03:30 PM.
#8
Posted 24 July 2011 - 09:55 PM
Study results on ginkgo are varying. Some studies say its no better then placebo, but some say it has a significant effect on tinnitus. If you`re trying ginkgo for tinnitus, i think the only way to find out if it works is to take it for at least 6-8 weeks before judging.
But the thing that is by far the most important of all is try not to be bothered by it. When you keep on focussing on your tinnitus and get stressed about it, your brain will keep labeling the sound as a threat and thereby labeling it as "important". This is bad for two reasons;
* Worrying about your tinnitus causes stress. The response to stress = heightened senses (including hearing) causing more sound and more stress. I can tell by experience this is a nasty vicious circle that you want to get yourself out of.
* As long as there is a stress reaction to your tinnitus your brain will not learn that the sound is unimportant. Whenever your brain does learn the sound is unimportant however, it will "filter it out" just like people that move to the city and don`t hear the traffic anymore after a couple of weeks, unless they choose to.
Please beleive me on this. I know I didn`t when I first had tinnitus. But now that I do, i notice the volume has come down alot and i`m not bothered by it at all. I still hear it at night, and sometimes it gets a little louder but it doesn`t influence my life anymore in the slightest bit.
Edited by DaneV, 24 July 2011 - 10:19 PM.
#9
Posted 25 July 2011 - 02:00 AM
#10
Posted 25 July 2011 - 03:00 AM
It's in the brain, but I'm not sure I'd call it a cause, more of a "relay" or effect. The real cause is often damaged hair cells in the ear. When the brain doesn't get the basal level of stimulation it's expecting from the hair cells, it 'fills in the blanks' with its own phantom sound. If you want to avoid tinnitus, avoid noise and ototoxic drugs. If you can't avoid noise for some reason, take antioxidants and magnesium around and for a day or two after the noise exposure. (sorry, no ref on that; saw it a long time ago)I think for 9 out of 10 cases, the cause of tinnitus is in the brain; not in the ears.
#11
Posted 25 July 2011 - 06:37 AM
http://www.google.co...nAydT6TGoaVU7Vw
Ah ha, evidently both NAC and ALCAR may be good for treating noise induced tinnitus and hearing loss. It looks like they may have to be administered before and fairly shortly after exposure to make a difference. It still may be possible to benefit from taking either long after exposure and damage.
Here's the abstract of the study spoken of in the article, I think:
Pharmacological rescue of noise induced hearing loss using N-acetylcysteine and acetyl-L-carnitine.
Coleman JK, Kopke RD, Liu J, Ge X, Harper EA, Jones GE, Cater TL, Jackson RL.
Source
Department of Defense Spatial Orientation Center, Department of Otolaryngology, Naval Medical Center, San Diego, CA 92134, USA.
Abstract
Despite the use of hearing protection devices (HPDs) and engineering changes designed to improve workspaces, noise-induced hearing loss continues to be one of the most common and expensive disabilities in the US military. Many service members suffer acoustic trauma due to improper use of HPDs, sound levels exceeding the protective capacity of the HPDs, or by unexpected, injurious exposures. In these cases, there is no definitive treatment for the hearing loss. This study investigated the use of the pharmacological agents N-acetylcysteine and acetyl-L-carnitine after acoustic trauma to treat cochlear injury. N-Acetylcysteine is an antioxidant and acetyl-L-carnitine a compound that maintains mitochondrial bio-energy and integrity. N-Acetylcysteine and acetyl-L-carnitine, respectively, significantly reduced permanent threshold shifts and hair cell loss compared to saline-treated animals when given 1 and 4 h post-noise exposure. It may be possible to obtain a greatertherapeutic effect using these agents in combination or at higher doses or for a longer period of time to address the secondary oxidative events occurring 7-10 days after acute noise exposure.
Edited by MorganM, 25 July 2011 - 06:48 AM.
#12
Posted 26 July 2011 - 08:55 AM
What psycho-actives are known to make tinnitus worse? Those that increase brain levels of serotonin? And if this is true, why do such supplements calm my mood better than anything else, if, indeed, stress is a co-factor? I wonder if the worsened tinnitus is a rebound effect associated with when serotonin levels drop off again. hmm
#13
Posted 26 July 2011 - 02:39 PM
#14
Posted 27 July 2011 - 12:39 AM
"Drugs that commonly cause or increase tinnitus -- these are largely ototoxins.
NSAIDS (motrin, naproxen, relafen, etc)
aspirin and other salicylates
Lasix and other "loop" diuretics
"mycin" antibiotics such as vancomycin (but rarely macrolides such as azithromycin)
quinine and related drugs
Chemotherapy such as cis-platin"
#15
Posted 28 July 2011 - 04:53 AM
#16
Posted 28 July 2011 - 09:44 AM
Circulatory supplements and drugs like ginkgo
and the commonly prescribed calcium blocker,
cinnarizine (Stugeron) will only work if your tinnitus
is of a vascular origin, i.e. caused by poor circulation
in the peripheral part of the auditory system, typically
the inner ear.
In most cases of tinnitus, they don't work. In fact,
ginkgo worsens it in my case.
As mentioned above, the majority of tinnitus cases
are of a central origin, which I am certain applies to
me as well.
I believe I had a ministroke, a hemorrhagic one, not a
TIA, when I was 17, which likely caused permanent
damage of the 8th nerve in its central origins. None of
the doctors at that time even remotely suspected this
as the cause - I've had myelograms, brachial angiograms
and radio isotope brain scans (they didn't have CAT and
MRI machines at that time).
Even to this day, most ENT doctors in Malaysia
know little about tinnitus, likely the most complex
and difficult to understand symptom, and the most
difficult to treat, in the world, with a million and one
possible different causes, and just as many different
possible treatments.
It was only when chatting with a nurse from Texas
on ICQ some ten years ago that she was sure I had
had a stroke from the symptoms I described to her
at the onset of tinnitus at that time.
Straining my eyesight, particularly when looking at
the computer screen without glasses, triggers off
a sudden higher pitch in my tinnitus. This is the
closest explanation I can find.
http://www.mult-scle...1/Tinnitus.html
Countless things have been tried at one time or
another for this. Even naltrexone.
http://tinnitussuppo...-or-Useful.html
Edited by tham, 28 July 2011 - 09:50 AM.
#17
Posted 28 July 2011 - 10:02 AM
but I believe phantom eye syndrome is the closest
analogy to it.
http://en.wikipedia....om_eye_syndrome
The brain is effectively hearing a sound which
does not exist.
GABA channels have been implicated in
tinnitus signalling, and GABA-type drugs,
plus benzodiapines, should in theory at least,
reduce tinnitus.
Abraham Shulman of the Martha Entenmann
Tinnitus Center in Brooklyn has done much
of the research on this.
http://www.ncbi.nlm....t_uids=14763233
http://www.ncbi.nlm....t_uids=14763326
http://www.ncbi.nlm....t_uids=11233342
However, there was a woman in one of the Yahoo
support groups who mentioned that her tinnitus
actually started after taking gabapentin and clonazepam.
#18
Posted 04 August 2011 - 05:09 AM
#19
Posted 04 August 2011 - 01:47 PM
The doc was an older and very experienced guy and told me tinnitus is usually caused by three main things: hearing loss, TMJ, and grinding teeth. I don't have TMJ and I don't think I grind my teeth at night but he suggested I get a bite guard made to sleep with just to make sure. He also told me to sleep with a white noise sound generator on (which I already did).
For me the hearing damage may have been caused by shooting guns without ear protection when I was a boy. He said a 4000 Hz hearing loss would jive with that. A dose of a benzo at bedtime definately helps me control my symtoms. Stress and anxiety definately makes it worse.
I have since though of an idea for me. Since my hearing loss is only at 4000 Hz I wonder what would happen if I got a pair of cheap hearing aids which were set to amplify only that frequency? Although 4000 Hz is not heard often by itself it probably is present in the ambient everyday noise we hear??? Perhaps my brain is creating this phantom sound because it can hear frequencies above and below this range. Maybe just wear them at night and/or around the house to retrain my brain. I might look into that.
#20
Posted 04 August 2011 - 03:37 PM
#21
Posted 04 August 2011 - 08:00 PM
I have since thought of an idea for me. Since my hearing loss is only at 4000 Hz I wonder what would happen if I got a pair of cheap hearing aids which were set to amplify only that frequency? Although 4000 Hz is not heard often by itself it probably is present in the ambient everyday noise we hear??? Perhaps my brain is creating this phantom sound because it can hear frequencies above and below this range. Maybe just wear them at night and/or around the house to retrain my brain. I might look into that.
A "dip" at 4 khz in your audiogram is typical
of noise-induced hearing loss.
Tinnitus is associated with a good percentage of
people with hearing loss, and the tinnitus frequency
tends to correlate and "replace" that of the hearing
frequency which has been lost.
A tinnitus instrument, which is a masker plus hearing
aid in one device, may help in your case. Your audiologist
or ENT should be able to advise you on that.
http://www.generalhe...quilcombinatio/
http://hearing.sieme...s-solutions.jsp
#22
Posted 04 August 2011 - 10:22 PM
#23
Posted 07 August 2011 - 10:07 AM
#24
Posted 07 August 2011 - 12:38 PM
#25
Posted 07 August 2011 - 12:49 PM
#26
Posted 07 August 2011 - 01:27 PM
#27
Posted 07 August 2011 - 01:58 PM
I'm a typical tinnitus sufferer in that I have high frequency hearing loss that corresponds to the tinnitus frequency. I've thought about trying something like you're talking about, but have never actually done it. I'd be interested in your experiences with it, should you explore it further. A 50 db notch is a pretty huge dropout. If the hair cells in that range are utterly and thoroughly dead, then feeding them a higher amplitude sound may not make a difference. It might be, on the other hand, that stimulating a frequency that was close enough to the tinnitus frequency might do the trick, so partially active hair cells that are 'close enough' might work. I haven't done any research into this, so all this is just my speculation. I hope you have some luck with it.Hum, I'll have to look at that again. What I had in mind was to listen to music, relaxing noise, etc with the 4000 Hz noise added to the point that my brain can hear it. It would seem to me that this would sound natural to my brain (the 4000 Hz notch would be gone) and therefore my brain wouldn't generate the false noise. I have a 50 dba notch at 4000 Hz.
#28
Posted 07 August 2011 - 02:11 PM
Now how do I figure out the frequency of my tinnitus? I had done a check up last year (when it started) and my diagram read about as to be expected at my age... If it matters, I am pretty sure mine was initially stress related as I had only very marginal exposure to noise in the past few years, I usually listen to music with good In Ear Headphones but at what I consider to be pretty sane levels, very little club going or concert inflicted exposure, either.
Edited by nupi, 07 August 2011 - 02:14 PM.
#29
Posted 07 August 2011 - 02:27 PM
Tinnitus: from the Latin word tinnire meaning to ring
Tinnitus is a subjective disorder characterized as chronic ringing, roaring, buzzing, humming, chirping, or hissing in the ears in the absence of environmental noise (ATA 2002). Symptoms of tinnitus are frequently found in elderly persons and are often associated with hearing loss related to the aging process (presbycusis). Although the cause is usually unknown, tinnitus can be a symptom of almost any ear disorder, including infection (otitis media), a blocked ear canal (ear wax) or eustachian tube, otosclerosis (overgrowth of bone in the middle ear), labyrinthitis, and Meniere's disease. Even blast injury from explosions has been known to cause symptoms of tinnitus. Additionally, adverse side effects from some drugs (e.g., aspirin and antibiotics) cause tinnitus symptoms.
Sometimes tinnitus is called "head noise." In tinnitus, the acoustic nerve transmits impulses to the brain that are not the result of vibrations produced by sound waves. Instead the impulses are the result of stimuli that originate inside the head or within the ear. In healthy ears, thousands of auditory cells maintain an electrical charge. There are microscopic hairs on the surface of each auditory cell that move in relation to the pressure of sound waves. Movement of the hairs discharges electrical charges through the hearing nerve to the brain. The brain interprets these electrical signals as sound. If the hairs are damaged, they move erratically and are in a constant state of irritation. As a result, the auditory cells cannot hold their charge and random electrical impulses flow to the brain as noise (MFMER 2001).
In most persons, the noise of tinnitus is present continuously, even if the person is not always aware of it. Tinnitus can change in nature or intensity. Tolerance of tinnitus varies from person to person and is largely determined by personality. Many people accept tinnitus without significant distress, but for some the noise is almost intolerable (ATA 2002).
Tinnitus affects 35-50 million persons in the United States, with 12 million people being severely affected (ATA 2002). Tinnitus may disappear independently or it can disappear when an underlying problem is successfully treated. In cases of chronic tinnitus for which there is no treatable underlying problem, a variety of therapies and suggestions may help to provide substantial relief for persons who suffer from the symptoms.
Diagnosis
See a physician to discuss your symptoms: when they began, their severity, and what seems to make them worse. Be sure to include information about any health conditions you have (e.g., high blood pressure) and what medicines you take. First, any accumulation of earwax or an infection will be eliminated as a possible cause. The physican will also attempt to hear the noise you describe using a stethoscope. If noise can be heard from a vascular condition, you have objective tinnitus. However, if damage to the inner ear is causing your tinnitus, you will be the only person who can hear the noise (subjective tinnitus) (MFMER 2001). Your physician may refer you to other specialists such as an otolaryngologist or audiologist in an attempt to learn more about the cause of your tinnitus.
Treatment
The treatment of tinnitus depends on the cause. As noted earlier, if the tinnitus is caused from a health condition, there may be steps your physician can take to eliminate or reduce the noise: removing earwax, treating an ear infection, correcting a vascular condition, changing or discontinuing a medicine, or recommending a hearing aid (MFMER 2001). If tinnitus is caused by age-related hearing loss or damage to your ears from exposure to excessive noise, there is no treatment to reduce the noise (MFMER 2001; NIH 2001). Instead, treatment consists largely of managing the condition. Not every suggested treatment works for everyone, so you may need to try several to find one that will help. It is important to avoid anything that could make your tinnitus worsen, including smoking, alcohol, and loud noises. If you are a construction worker, an airport worker, a hunter, or are often exposed to loud noise at home or at work, you should wear ear plugs or special ear protection (muffs) to protect your hearing (NIH 2001).
Lifestyle Changes
Sometimes symptoms of tinnitus improve with time. However, many people must learn to make adjustments to their lifestyle (coping skills) (MFMER 2001; NIH 2001). Try some of these techniques to help reduce the severity of tinnitus and to increase your tolerance of it:
*Avoid irritants. Tinnitus can be aggravated by loud noises, nicotine, caffeine, tonic water containing quinine (used to treat malaria), alcohol, and excessive doses of aspirin. Nicotine and caffeine constrict blood vessels, increasing the force of blood through veins and arteries. Alcohol also increases the force of blood by increasing the speed of blood flow.*Mask or cover up noise. A fan or soft music can help mask the noise of tinnitus. Tinnitus maskers are devices that are similar to hearing aids in appearance, but they produce a pleasant sound. Listening to recordings of soothing music or sounds such as ocean waves may help cover the unwanted noise, especially while sleeping. There are some electronic sound devices that provide several relaxing sounds to facilitate sleep by masking tinnitus.*Use a hearing aid. If you have tinnitus that is accompanied by a loss of hearing, a hearing aid can amplify outside sounds and possibly make tinnitus noise less noticeable.*Reduce stress. Stress seems to make tinnitus worse. Learn how to relax when the noise in your ears is frustrating. Practicing stress management (relaxation therapy, biofeedback, or exercise) may provide some relief. Engaging in regular exercise may also provide relief by increasing blood circulation to the head.*Reduce use of salt. This can increase the buildup of fluid in the ear.Dietary Supplements
Ginkgo Biloba
A plant extract used to reduce the symptoms of cognitive deficits such as decreased memory function, poor concentration, and reduced alertness, ginkgo biloba has been shown to have positive results in the treatment of tinnitus and dizziness in the scientific literature (Stange et al. 1975; Jung et al. 1998). Studies have shown that 120-240 mg a day of pharmaceutical-grade ginkgo biloba extract can alleviate tinnitus, although some earlier studies failed to show benefits (Burschka et al. 2001). The therapeutic effect of ginkgo biloba is attributed to several active constituents with vasoactive and free-radical-scavenging properties.
In a study conducted in Denmark, tinnitus and dizziness were reduced after a treatment of 4-6 weeks with ginkgo biloba. Researchers also noted that there were minimal side effects in patients who followed the recommended dosage (Soholm 1998).
Another controlled study showed that ginkgo extract caused a statistically significant decrease in behavioral manifestation in the animal model of tinnitus (Jastreboff et al. 1997). In human studies, it was shown in patients who had cerebrovascular insufficiency (a common condition associated with normal aging) that ginkgo extract produced a significant improvement in the symptoms of vertigo, tinnitus, headache, and forgetfulness (Holstein 2001; Morgenstern et al. 2002).
Melatonin
Rosenberg et al. (1998) evaluated a treatment for subjective tinnitus at the Ear Research Foundation in Sarasota, Florida. Patients were given 3 mg of melatonin nightly for 30 days. In patients with difficulty sleeping due to the symptoms of tinnitus, an overall improvement was seen in 46% of the study group as opposed to 20% in the group given placebo. The researchers also concluded that patients with bilateral (two-sided) tinnitus showed significant improvement over those with unilateral (one-sided) tinnitus. Because of the minimal side effects associated with melatonin, it is considered a safe alternative treatment for chronic tinnitus (Rosenberg et al. 1998).
B Vitamins
According to Michael Seidman, M.D. (Tinnitus Center in Bloomfield, Michigan), there are specific nutrients that have been suggested to benefit persons with tinnitus. B-complex supplements lead this category because deficiencies in the B vitamins have been shown to result in tinnitus. The B vitamin complex stabilizes nerves and appears to have a beneficial effect on some tinnitus patients. However, only anecdotal evidence is available on this therapy.
Some patients say vitamin B1 (thiamine) supplemented at 100-500 mg daily has provided them with relief from symptoms. Vitamin B3 (niacin) is the subject of numerous anecdotal reports that purport it to help reduce symptoms. Dr. Seidman usually recommends a starting dosage of 50 mg twice a day of niacin, up to a maximum of 500 mg twice a day, but he believes that if there is no improvement within 3-4 months, it is unlikely to occur.
There may also be some correlation between the decline in vitamin B12 levels and the increasing prevalence of tinnitus in the elderly. A study by Shemesh et al. (1993) showed that there was a high prevalence (47%) of vitamin B12 deficiency in patients with chronic tinnitus. This deficiency was more widespread and severe in the tinnitus group that was associated with noise exposure, suggesting a relationship between vitamin B12 deficiency and dysfunction of the auditory pathway. Supplemental cobalamin was found to provide some relief in several patients with severe tinnitus.
Zinc
Studies have shown that there is a high content of zinc in the inner ear. Ochi et al. (1997) demonstrated that patients who had tinnitus had significantly decreased zinc levels and that supplementation with doses of 34-68 mg of zinc for more than 2 weeks significantly improved their tinnitus. Excellent results were also found by combining niacin with 25 mg zinc gluconate twice daily.
Magnesium
People in large cities are exposed to potentially damaging loud noises on a daily basis. Studies have shown that noise exposure causes magnesium to be excreted from the body (Mocci et al. 2001). It is possible that supplementing with magnesium could reduce noise-induced ear damage and thus reduce the likelihood of new-onset tinnitus. Few studies document that magnesium relieves tinnitus symptoms, but many patients have experienced relief by using magnesium (Attias et al. 1994).
Other Supplements
Hydergine, the ergot derivative, at a dosage level of 10-15 mg daily, has been shown to alleviate tinnitus in some people. In one study as little as 4.5 mg a day improved tinnitus by 57.1% (Jimenez-Cervantes et al. 1990). Vinpocetine, the cerebral vasodilator, can also be effective at a dosage of 20-40 mg daily. In one study, after acoustic trauma, tinnitus was improved 66% by using vinpocetine (Konopka et al. 1997).
#30
Posted 08 August 2011 - 01:56 AM
Edited by Robert C, 08 August 2011 - 01:57 AM.
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