hmm, if my calculations are right, it would mean you'd have to take about 60grams of it considering you have 5 liters of blood. and the effects would hardly build up over time as piracetam is excreted even with renal impairment you'd have to make a huge overdose of it.Piracetam effect might built up overtime and then it can built to greater than 70mM so toxicity occur.
tomorrow i will take half a half a half of 800mg pill (~100mg ) and see any effect better than ~200mg that i take daily.
As for depression it is indeed a negative side-effect of piracetam that has been reported numerous times. Try adding Aniracetam and/or Se-Methyl L-Selenocysteine to your stack to counter the effects.
Edited by renfr, 01 January 2012 - 03:48 AM.