You do realize that most of the world's population has HSV1 right?
Doesn't this mean that many people with the Apo-e4 gene like myself are basically screwed?
Not really. You found out your genotype, so now you can take steps to avoid problems down the road. The HSV Alzheimer's connection isn't all that solid, imho, and the Apo E4 risk factor isn't infinite; you have something like double the risk of ApoE 3, or thereabouts, right? And those numbers were generated from people who didn't know their genotype, and didn't tune their diet, supplementation, and other behaviours to reduce risk. I would do the following:
Take some steps to keep herpes under control. There are a variety of oral and topical medicines. Try to avoid immunosuppression.
Learn how much aluminum is in your water. Figure out ways to reduce your aluminum exposure. Lately I've been looking into putting a few drops of BioSil or JaroSil into a pitcher of water to bind up the aluminum. I checked with my water department, and it's right on the borderline between "high" and "low", based on at least one paper. I've cut back a lot on aluminum chloride antiperspirants. They don't smell so good if you look at the epidemiology on them.
Tune your diet to be right from a cardiovascular disease standpoint, and you should be ok.