11 replies to this topic

[unregistered_user]

I'm sure others here have experimented with this combination but I figured I'd start a thread so we could group together all the opinions and experiences.

My fish oil and piracetam dosage varies day by day but the minimum amount I consume daily is about 10 grams of each with the eventual goal to be 15g. In addition to this I take 3-5mg of liquid deprenyl (Dep Pro) per day. Notice the lack of choline supplementation. I'm not convinced it's necessary and I don't get headaches even when taking 15g of piracetam per day.

So far I've only experienced dullness, irritation, fatigue and brainfog. I haven't noted any positive effects yet although I did try piracetam about 6 months ago and experienced many of the usual positives (effortless locution, increased focus, mild energy increase, etc.) so I'm hoping after a couple of weeks I'll become reacquainted with those effects. For now, I'm struggling to articulate my thoughts, can't think abstractly and in general feel maladroit. It's like every facet of my being is blunted (emotions, mental acuity, interest..)

Anyone else on this combo? How long before you started seeing effects? I have a hard time differentiating between the effects of the piracetam and deprenyl but am starting to be able to tell them apart. I think they are both going to be a slow bake so I need to suspend my anticipation and let their respective effects begin to unfold.

I am still hopeful that this will be an effective combo for increasing cognitive abilities, motivation, and interest in accomplishing goals while at the same time maybe offering a slight boost in confidence and social aptitude.

[MrSpud]

Isn't 10 grams of Piracetam a day a pretty high dose. I thought Racetams had an inverted u shaped dosage curve where as you increase the dose from very low the effects get stronger, them max out and then higher doses than that have a lesser effect. I thought that after initially taking an attack dose when you first start taking it that afterwards you would take less.

What I am getting at is maybe you are just taking too high a dose of Piracetam?

[Dirk_Diggler]

10 grams is pretty high. I used to take 10 grams before going to sleep to increase dream vividity. But piracetam is so benign some people do mega dose (Isochroma?) and have positive effects.

[unregistered_user]

You are both correct, for the most part. Some people respond to larger doses and I think more people should consider "mega dosing" considering piracetam has no LD50. You can eat a whole tub of it and the worst side effect you'll likely encounter will be a nap.

I find that as I continue high dosages my responses become more favorable. I've tried taking 800mg regularly before with moderate success. I even microdosed at 100-200mg a time or two per day so I decided to see what things were like on the other end of the spectrum.

I think the majority of my undesirable effects are coming from the Deprenyl but I don't believe this is uncommon. I will continue with the protocol and report back.

There are multiple users on here taking in excess of 10g of piracetam with positive results. MrSpud, your thinking is definitely valid but I'm not convinced the bellshape response curve is applicable to everyone.

[Dirk_Diggler]

MrSpud, your thinking is definitely valid but I'm not convinced the bellshape response curve is applicable to everyone.

I always wondered about that bell-shaped curve theory. Everyone is different and I never had any negative side effects from taking high doses of piracetam. But I never took more than 20 grams in a day. One researcher claimed it was "as safe as salt" but I think it may actually be even safer than that. Try eating a tub of salt...would be more dangerous than eating a tub or piracetam.

I've noticed that tolerance to piracetam is one limiting factor in megadosing. I get to a point where 10 grams won't do anything and then it starts getting expensive and you don't get the benefits of it anymore.

I think it's interesting that megadoses of piracetam have anectodally been linked to mania. I've never experienced it, but I think we can all think of at least one person who has...

[MrSpud]

I don't think it is necessarily dangerous to take the higher doses, just that the effect might be less than if someone titrated themselves and found the optimal dose. Higher doses might lower the effect down to the point that less benefit is seen. Maybe...

When I first tried piracetam I was taking a bunch of other stuff with it, mainly different types of cholinergics, and barely was getting any effects. Then, after a while I started getting all kinds of negative effects and I ended up having to figure out what was going on. I ended up figuring out what was going on and had to back off of a lot of things and only take them one at a time on diffeent days and also had to take lower doses, then they started working much better. If I would of just thought that I had to keep taking more I probably would have messed up and missed the sweet spot with some of them or concluded they didn't work. Just something to keep in mind in case the deprenyl is making it so that a lesser dose of piracetam might give greater effects than a larger dose.

Edited by MrSpud, 13 September 2011 - 03:42 AM.

[unregistered_user]

MrSpud, I don't contend anything you've said. Good post.

Incidentally, my experience so far is still lacking positive results. I've been cloudy headed, irritable, and more out of sorts than usual. I have noticed a much enhanced visual perception but that's about it. I will continue with my regime and listening to my body. Today I got a pounding headache which I assume was from the 6g of piracetam I took this morning so I took 2g of ALCAR.

[longevitynow]

With hundreds of doses of both piracetam and deprenyl behind me, I can say I notice much more from both when I take them occasionally, not daily. 1-5 drops of liquid selegiline sublingually is like viagra for my brain when taken, say once a week. If I take it for 2-3 days in a row, then I find it is a very mild cognitive stimulant, rather than as the premier tool for enhancing public speaking (when taken weekly, say). I've had better results with daily piracetam dosing, but even so, the really creative or slight hypomanic episodes from Piracetam have tended to come when I had not been taking it for a while and decided to do 3-4 grams with a little choline and perhaps caffeine or deprenyl.

[unregistered_user]

Very interesting post longevitynow. I've been dosing 12g piracetam and 5mg deprenyl daily and have been feeling "pretty good", I'd say about a 6.5-7/10.

I'll test your theory and reduce my dosage to a couple of times per week to see how that does me. Thanks for sharing.

[mikey]

So, I'm still trying to determine whether to take deprenyl with racetams or not. Seems to be questionable.

 

More to study...

[burnlife]

I wonder if the the members of longecity are still of the opinion that piracetam is essentially harmless, even in high doses.

Edited by burnlife, 15 June 2015 - 04:45 AM.

[maik2013]

Very interesting post longevitynow. I've been dosing 12g piracetam and 5mg deprenyl daily and have been feeling "pretty good", I'd say about a 6.5-7/10.
 

 

I think every racetam has a kind of immediate feeling to it. Many people get better vision, or more confidence, it has some definite impact, at almost no (feelable) side effects. But i think that's exactly why they're dangerous. I think racetams are a class of drugs, that are very strong. They have a big impact on the brain and people tend to overlook the side effects, which is typical for dangerous drugs. Another very harmful thing is, that the combination of these facts plus the establishment just ignoring it  makes the drug cool and the following a bit like a cult. You might compare it with people, who praise  Putin ignoring that he is just as bad. Racetams have an extreme tolerance issue and they do have side effects, which include character changes to the negative, hair loss, and impaired brain functioning. How can this be possible? Because the brain has a thousand functions, if you suddenly become super fluent, it comes at a price that you might forget other things. There is only so much processor capacity. As i have mentioned before, if you write a book or work on some super complicated thing and need a break through and you're safe from every day distractions then you might try them, but if you're just an average joe with an average job, it's very much a waste, which brings me to my final point. The waste of time and money, while there are much better alternatives. You have to consider generally that like in the quote above people are different. These kind of people, who "feel good" shouldn't even post. What i do is with every post on longecity, or reddit nootropics which i think could have value, is to click on the name of the poster and review his other posts. This way you most often find the problems. First of all their seemingly perfect plan changes every few weeks. They encounter bad side effects or they're a bit like junkies, who test all kind of drugs. I'm not blaming them, it's entirely the fault of this health system. I'm writing this on 1.25mg Deprenyl and i'm amazed by the effects. This could be it. Will i try to enhance it? Probably, but racetams are last on the list and i have all four racetams in pharmaceutical quality. They're just completely overrated.