![:)](http://www.longecity.org/forum/public/style_emoticons/default/smile.png)
Time to start making yourself feel better.
Posted 10 January 2012 - 07:47 PM
Posted 10 January 2012 - 07:53 PM
Not a complete waste. I'd say perfect - you're now at 10 days, where you can start scaling back on the nicotine and harmful stuff and you shouldn't feel terrible.
Time to start making yourself feel better.
Edited by nito, 10 January 2012 - 08:02 PM.
Posted 10 January 2012 - 08:32 PM
Posted 11 January 2012 - 02:07 AM
Posted 11 January 2012 - 02:17 AM
If you are depressed, or schizophrenic or have Alzheimer's, scientists say you probably have a shrunken hippocampus. The good news: a drug that just entered human trials promises to re-grow that part of the brain.
It's an entirely new approach to treating clinical depression, which is the first of several diseases scientists at biotech company Neuralstem are hoping to address with their experimental oral drug. Most antidepressants work on brain chemistry, tweaking levels of neurotransmitters including serotonin, norepinephrine, and dopamine. This is the first drug that aims to re-grow patients' atrophied brains.
Dr. Karl Johe, Neuralstem's CEO, believes that depression is a three-headed beast that affects neurotransmitter levels, neurons, and hippocampus size. And he says their new drug could address all three. He also hopes the drug will reverse the disease to the point that patients could permanently go off the drug.
"If we can show by MRI that we've increased hippocampus volume and at the same time reversed depression symptoms for six months after patients have stopped taking the drug, then we'll have a cure."
That a too-small hippocampus causes depression and other diseases is still technically a theory in humans (though it's been demonstrated in rats and chimps). So if the drug grows hippocampus volume and thereby treats depression, we'll not only have a new treatment, but the study results would be proof that a shriveled hippocampus is at least in part the culprit.
Posted 11 January 2012 - 02:20 AM
Posted 11 January 2012 - 02:27 AM
Posted 11 January 2012 - 02:39 AM
Posted 11 January 2012 - 03:24 AM
http://m.gizmodo.com...wing-your-brain
Depression cured by increasing the size of the hippocampus.
Different drug, same effect.If you are depressed, or schizophrenic or have Alzheimer's, scientists say you probably have a shrunken hippocampus. The good news: a drug that just entered human trials promises to re-grow that part of the brain.
It's an entirely new approach to treating clinical depression, which is the first of several diseases scientists at biotech company Neuralstem are hoping to address with their experimental oral drug. Most antidepressants work on brain chemistry, tweaking levels of neurotransmitters including serotonin, norepinephrine, and dopamine. This is the first drug that aims to re-grow patients' atrophied brains.
Dr. Karl Johe, Neuralstem's CEO, believes that depression is a three-headed beast that affects neurotransmitter levels, neurons, and hippocampus size. And he says their new drug could address all three. He also hopes the drug will reverse the disease to the point that patients could permanently go off the drug.
"If we can show by MRI that we've increased hippocampus volume and at the same time reversed depression symptoms for six months after patients have stopped taking the drug, then we'll have a cure."
That a too-small hippocampus causes depression and other diseases is still technically a theory in humans (though it's been demonstrated in rats and chimps). So if the drug grows hippocampus volume and thereby treats depression, we'll not only have a new treatment, but the study results would be proof that a shriveled hippocampus is at least in part the culprit.
Edited by nito, 11 January 2012 - 03:38 AM.
Posted 11 January 2012 - 04:59 AM
Posted 11 January 2012 - 06:32 AM
Posted 11 January 2012 - 08:51 AM
Posted 11 January 2012 - 08:57 AM
It competes on some aspects and amplifies others.
I have my suspicions, but no human examples - would you be open to weaning off the nicotine for the trial? Should be easy on uridine. I suspect you may not need it.![]()
Posted 11 January 2012 - 09:21 AM
Posted 11 January 2012 - 11:05 AM
Posted 11 January 2012 - 11:09 AM
Posted 11 January 2012 - 01:38 PM
Posted 11 January 2012 - 03:17 PM
Edited by manic_racetam, 13 February 2012 - 04:47 PM.
Posted 11 January 2012 - 04:38 PM
Posted 11 January 2012 - 04:42 PM
Posted 11 January 2012 - 08:26 PM
Posted 11 January 2012 - 09:20 PM
Posted 11 January 2012 - 09:31 PM
Posted 12 January 2012 - 02:27 PM
Edited by manic_racetam, 13 February 2012 - 10:00 PM.
Posted 12 January 2012 - 03:58 PM
Posted 12 January 2012 - 06:19 PM
Posted 12 January 2012 - 06:51 PM
I have located a full paper on why you would take DHA,EPA + UMP/TAU together. Take a look at the actual phospholipid increases shown in table 2 / page 4. *WOW*.
http://wurtmanlab.mi...ic/pdf/1037.pdf
Posted 12 January 2012 - 07:28 PM
Sorry, I didn't have the attention span to read through the entire thread, but as someone who suffers from ADD, OCD, depression and sleep problems, I'm definitely interested in trying Uridine ..
Just a couple of questions:
1) Did anyone here who felt worse on DHA as a standalone supplement feel better on the combination? I'm not sure, but I feel like DHA (from neuromins) makes me feel a little more depressed; I also tried a high-DHA fish oil supp. which seemed to increase my anxiety.
2) I can't tolerate methylfolate either (causes anxiety, agitation); could I get away without supplementing it?
would just a b-complex (Jarrow's b-right) do?
I was planning to avoid choline since it's reportedly not so great for OCD or depression.
Edited by ScienceGuy, 12 January 2012 - 07:30 PM.
Posted 12 January 2012 - 10:24 PM
Posted 13 January 2012 - 02:49 AM
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