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GPC (choline), Uridine, DHA

choline uridine dha omega-3 epa ump tau b vitamins

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#1681 cap3

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Posted 19 December 2012 - 09:27 PM

I definately agree its both serotonin and dopamine in my case at least.

But when I take 5htp or tryptophan they just make me somewhat lethargic the next day. Plus my sleep quality is always pretty good and I have no problems falling asleep either. In fact the best treatment for my depression so far has been cutting my sleep to a maximum 7 hrs.

SAMe looks like a really good option for depression and other health benefits, unfortunately gave me very bad nervousness even at just 200mg a day.



#1682 Hope47

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Posted 20 December 2012 - 05:24 AM

@Guardian:What do you say about someone who relieves himself 2 times a day?.Does that person have high dopamine

Edited by Hope47, 20 December 2012 - 05:24 AM.


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#1683 synaptiq

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Posted 20 December 2012 - 04:45 PM

Depending on what you mean by "relieves himself," either:
1) he mostly just needs to drink more water, or
2) he should watch out for tennis elbow

Edited by synaptiq, 20 December 2012 - 04:45 PM.

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#1684 Renegade

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Posted 20 December 2012 - 05:34 PM

Does anyone have any views on the possibility of gaining the positive effects from uridine by consuming high doses of reishi mushroom, which contains uridine?

Edited by Renegade, 20 December 2012 - 05:34 PM.


#1685 Guardian4981

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Posted 20 December 2012 - 09:16 PM

I definately agree its both serotonin and dopamine in my case at least.

But when I take 5htp or tryptophan they just make me somewhat lethargic the next day. Plus my sleep quality is always pretty good and I have no problems falling asleep either. In fact the best treatment for my depression so far has been cutting my sleep to a maximum 7 hrs.

SAMe looks like a really good option for depression and other health benefits, unfortunately gave me very bad nervousness even at just 200mg a day.



Based on your ease of sleeping and reaction to 5-htp I would believe while you may be low on both dopamine is likely more severely low.

I too felt overly nervous when I first tried SAMe years ago. However now I do not feel this nearly as much if at all. I would imagine in my case its because since years ago I have lifted serotonin levels via lifestyle changes, better diet, better multi, meditation, handling stress better, etc. Perhaps a further component is your body handles SAMe better if you have taken it before.

If you try SAMe again, take it first thing when you wake up. Also be sure you are taking a good multi and magnesium/calcium. I would hold off on TMG as it can enhance SAMe which in your case could be a negative.

You also may wan to stack SAMe with Uridine, for me at least urdine seems to help serotonin alot. Uridine thus could help with your nervousness some.

However keep in mind "nervousness" can often be from one of two extremes. To low of serotonin or too high of serotonin both cause nervousness. In this regard the uridine could actually make you more nervous. I found the first few times I took uridine I had a bit of nervousness and I believe my serotonin was too high as I had early stage serotonin syndrome symptoms.

I would also encourage insight meditation as a natural way to boost nerutransmitters.

#1686 Guardian4981

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Posted 20 December 2012 - 09:24 PM

@Guardian:What do you say about someone who relieves himself 2 times a day?.Does that person have high dopamine



It depends, high libido and need to relieve onself can have numerous biological and phsycological sources.

The best way to determine if its dopamine related is how much sensitivity one feels down there while at it. At times I have had high libido yet somewhat de sensitized feeling, this often occured from higher serotonin but lower dopamine.

If you have never had low dopamine then higher it would be difficult to know what is alot of sensitivity or not since you may be so used to something.

A classic sign of low dopamine is difficulty climaxing, so if you feel the urge to relieve yourself yet have a hard time actually finishing then you may have higher serotonin but lower dopamine, I been there!

All that said, overall yes I would say someone that has to relieve twice a day has high dopamine because when I have used anything that boosts my dopamine I become like a rabbit! On the other hand when my dopamine is low I can go days or even weeks and not care much at all.

#1687 Guardian4981

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Posted 20 December 2012 - 09:30 PM

Does anyone have any views on the possibility of gaining the positive effects from uridine by consuming high doses of reishi mushroom, which contains uridine?



I think the general consensus of this thread is getting uridine from sources such as brewers yeast never is as effective as taking uridine as a standalone product.

As an aside, when I use reishi I get super lethargic! Its great for helping my nasal issues but I'd imagine its such a strong anti histamine that it makes one drousy.

#1688 csrpj

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Posted 20 December 2012 - 10:49 PM

Any comments on the use of UMP vs TAU (at equivilant doses/ROAs)
One user here says that UMP sublingual works whereas TAU doesn't work at the same level. Can I get a confirmation on this, or should I assume that if TAU oral doesn't work then UMP sublingual wouldn't either?

#1689 Dissolvedissolve

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Posted 21 December 2012 - 01:26 AM

Any comments on the use of UMP vs TAU (at equivilant doses/ROAs)
One user here says that UMP sublingual works whereas TAU doesn't work at the same level. Can I get a confirmation on this, or should I assume that if TAU oral doesn't work then UMP sublingual wouldn't either?


TAU is a prodrug for uridine. So it's ideally bioavailable orally.

It's likely that the bioavailability of UMP sublingual is higher than UMP oral. And using, say, 250 mg of UMP sublingually is about as potent of an effect possible. I don't notice much of anything with 300 mg oral, but I do notice some calmness with 300 mg sublingually, for instance.

If you've tried 75-100 mg of TAU, you probably won't get any more effect with UMP sublingually, since TAU is quite potent. If you really want to see if there's any potential for uridine, you could also go higher than 100 mg. I believe Mr. Happy has said over 100 mg or so of TAU was excessive for him.

#1690 cap3

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Posted 21 December 2012 - 06:29 AM

I definately agree its both serotonin and dopamine in my case at least.

But when I take 5htp or tryptophan they just make me somewhat lethargic the next day. Plus my sleep quality is always pretty good and I have no problems falling asleep either. In fact the best treatment for my depression so far has been cutting my sleep to a maximum 7 hrs.

SAMe looks like a really good option for depression and other health benefits, unfortunately gave me very bad nervousness even at just 200mg a day.



Based on your ease of sleeping and reaction to 5-htp I would believe while you may be low on both dopamine is likely more severely low.

I too felt overly nervous when I first tried SAMe years ago. However now I do not feel this nearly as much if at all. I would imagine in my case its because since years ago I have lifted serotonin levels via lifestyle changes, better diet, better multi, meditation, handling stress better, etc. Perhaps a further component is your body handles SAMe better if you have taken it before.

If you try SAMe again, take it first thing when you wake up. Also be sure you are taking a good multi and magnesium/calcium. I would hold off on TMG as it can enhance SAMe which in your case could be a negative.

You also may wan to stack SAMe with Uridine, for me at least urdine seems to help serotonin alot. Uridine thus could help with your nervousness some.

However keep in mind "nervousness" can often be from one of two extremes. To low of serotonin or too high of serotonin both cause nervousness. In this regard the uridine could actually make you more nervous. I found the first few times I took uridine I had a bit of nervousness and I believe my serotonin was too high as I had early stage serotonin syndrome symptoms.

I would also encourage insight meditation as a natural way to boost nerutransmitters.


I have actually tried SAMe a couple of times and I'm very sensitive to it. It feels like its increasing all my negative symptoms especially nervousness around people. I think it may be increasing norepinephrine more than anything else.

I did have a hair test which confirmed very high calcium which may have contributed to the high norepinephrine. Perhaps I could try it again with magnesium and uridine.

I have some aniracetam on order at the moment and am going to try that first.

I have been trying meditation but i'm struggling with my level of mood to commit and motivate myself to keep it up!

#1691 Guardian4981

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Posted 21 December 2012 - 04:17 PM

I definately agree its both serotonin and dopamine in my case at least.

But when I take 5htp or tryptophan they just make me somewhat lethargic the next day. Plus my sleep quality is always pretty good and I have no problems falling asleep either. In fact the best treatment for my depression so far has been cutting my sleep to a maximum 7 hrs.

SAMe looks like a really good option for depression and other health benefits, unfortunately gave me very bad nervousness even at just 200mg a day.



Based on your ease of sleeping and reaction to 5-htp I would believe while you may be low on both dopamine is likely more severely low.

I too felt overly nervous when I first tried SAMe years ago. However now I do not feel this nearly as much if at all. I would imagine in my case its because since years ago I have lifted serotonin levels via lifestyle changes, better diet, better multi, meditation, handling stress better, etc. Perhaps a further component is your body handles SAMe better if you have taken it before.

If you try SAMe again, take it first thing when you wake up. Also be sure you are taking a good multi and magnesium/calcium. I would hold off on TMG as it can enhance SAMe which in your case could be a negative.

You also may wan to stack SAMe with Uridine, for me at least urdine seems to help serotonin alot. Uridine thus could help with your nervousness some.

However keep in mind "nervousness" can often be from one of two extremes. To low of serotonin or too high of serotonin both cause nervousness. In this regard the uridine could actually make you more nervous. I found the first few times I took uridine I had a bit of nervousness and I believe my serotonin was too high as I had early stage serotonin syndrome symptoms.

I would also encourage insight meditation as a natural way to boost nerutransmitters.


I have actually tried SAMe a couple of times and I'm very sensitive to it. It feels like its increasing all my negative symptoms especially nervousness around people. I think it may be increasing norepinephrine more than anything else.

I did have a hair test which confirmed very high calcium which may have contributed to the high norepinephrine. Perhaps I could try it again with magnesium and uridine.

I have some aniracetam on order at the moment and am going to try that first.

I have been trying meditation but i'm struggling with my level of mood to commit and motivate myself to keep it up!



Yes magnesium may be a good option.

Also SAMe seems to enhance what your body's genetic tendency is. What I mean by this is if your norepinephrine levels tend to be high SAMe will raise them. But what you can do is try to shift the focus.

Meditation tends to lower blood pressure, this in my view may indicate that it raises neurotransmitters that balance norepinephrine.

I find aerobic exercise seems to favor dopamine production.

The best I ever feel in life is when I take SAMe and then do aerobic exercise, but you need to do a good half hour or so to feel this.

#1692 MrHappy

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Posted 21 December 2012 - 10:55 PM

I'm going to have to admit defeat with the uridine.
After trying various dosages from just 50mg sub to 350mg orally it just makes me feel emotionally flat and irritable.

It's frustrating as I had high hopes for it considering 2grams of tyrosine gives me such good results. And with my social anxiety I am sure my problems are dopamine related.

May have to look at meds instead now.

50mg sub roughly equals 350mg orally.

What does your stack and diet look like?

Any comments on the use of UMP vs TAU (at equivilant doses/ROAs)
One user here says that UMP sublingual works whereas TAU doesn't work at the same level. Can I get a confirmation on this, or should I assume that if TAU oral doesn't work then UMP sublingual wouldn't either?


I could see it making a significant difference if absorption through the usual pathway wasn't efficient (liver, etc).

Which reminds me - I'm on holidays now - PM me your new address again and I'll send you a small Christmas present that hopefully arrives this time! :)

Edit: xmas party beverages have killed my typing today..

Edited by MrHappy, 21 December 2012 - 10:56 PM.


#1693 penisbreath

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Posted 24 December 2012 - 01:47 AM

is it possible to see benefits from taking uridine alone -- without the cofactors like fish oil?

#1694 synaptiq

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Posted 24 December 2012 - 03:15 AM

There are plenty of studies showing effects from uridine without supplemental DHA, but it's a major building block for neurogenesis and dendritic outgrowth and enhances the effect greatly. The B vitamin cofactors are important because they prevent the incorporation of uracil into DNA - they aren't strictly necessary to see the benefits of uridine but protect against its possible carcinogenicity. Choline is a mixed bag - some get depression from it, some get headaches without it, and some have room to play around with it.

Edited by synaptiq, 24 December 2012 - 03:20 AM.

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#1695 Hope47

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Posted 24 December 2012 - 04:49 AM

Saw some post here mentioning b-vitamins as cancerous.Can someone explain be how? I take sublingual b--complex.

Edited by Hope47, 24 December 2012 - 04:49 AM.


#1696 penisbreath

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Posted 24 December 2012 - 10:44 AM

There are plenty of studies showing effects from uridine without supplemental DHA, but it's a major building block for neurogenesis and dendritic outgrowth and enhances the effect greatly. The B vitamin cofactors are important because they prevent the incorporation of uracil into DNA - they aren't strictly necessary to see the benefits of uridine but protect against its possible carcinogenicity. Choline is a mixed bag - some get depression from it, some get headaches without it, and some have room to play around with it.


Choline I've never tried, but it seems to be contraindicated in OCD. B-vitamins I find relatively tolerable for the most part. I tried a pure DHA supplement, but it made me feel foggy and weird (like I was on a mood stabilizer) and I'm still unsure how fish oil effects me, so I was hoping I could just play around with Uridine on its own for now ..

#1697 nupi

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Posted 24 December 2012 - 10:55 AM

You could always try normal fish oil (with a slight EPA overhang), I never felt anything much from that... I like Life Extensions' Super Omega 3 but there are plenty of cheaper options, too (probably the best bang for the buck is between Costco's Kirkland Brand and NOW Ultra Omega).

Messing around with 50mg of CR TAU right now. Let's see if there is any real change from it (might be somewhat hard to see because I also upped my Prozac dose a little a couple of days ago and Prozac's pharmacology is such that this will not really hit me until a week or two in). UMP powder maybe cheaper but this is by far easier to use in the early morning :)

Considering that I usually hate the holidays, I am in exceptionally good mood today, so SOMETHING is clearly doing a good job.

Edited by nupi, 24 December 2012 - 10:58 AM.


#1698 cap3

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Posted 24 December 2012 - 11:41 AM

I'm going to have to admit defeat with the uridine.
After trying various dosages from just 50mg sub to 350mg orally it just makes me feel emotionally flat and irritable.

It's frustrating as I had high hopes for it considering 2grams of tyrosine gives me such good results. And with my social anxiety I am sure my problems are dopamine related.

May have to look at meds instead now.

50mg sub roughly equals 350mg orally.

What does your stack and diet look like?

Any comments on the use of UMP vs TAU (at equivilant doses/ROAs)
One user here says that UMP sublingual works whereas TAU doesn't work at the same level. Can I get a confirmation on this, or should I assume that if TAU oral doesn't work then UMP sublingual wouldn't either?


I could see it making a significant difference if absorption through the usual pathway wasn't efficient (liver, etc).

Which reminds me - I'm on holidays now - PM me your new address again and I'll send you a small Christmas present that hopefully arrives this time! :)

Edit: xmas party beverages have killed my typing today..


I was taking 50mg orally too for a couple of days but this still made me feel flat.

Included in my stack was
Vitamin E 400iu
Fish oil 700 Dha 200 EPA
Calcium/ magnesium tablet
Multi vitamin

I'm not sure if the multi vitamin has been making me feel worse. I might try excluding it for a few days.
It contains:


Ingredient Amoun
Vitamin C 240.9mg
Pantothenic Acid (Vitamin B5) 100mg
Niacin (Vitamin B3) 50mg
Vitamin E 75iu natural source 50mg Tocopherol Equivalents 417
Thiamine (Vitamin B1) 25mg
Riboflavin (Vitamin B2) 25mg
Vitamin B6 25mg
Magnesium 22mg
Inositol 12mg -
P.A.B.A. (para amino benzoic acid) 10mg -
Potassium 8.9mg
Zinc 8.5mg
Calcium 6mg
Vitamin A 600mcg
Folic Acid 400mcg
Manganese 300mcg
Molybdenum 98.7mcg
Selenium 50mcg
Chromium 50mcg
Iodine 37.8mcg
Biotin 35mcg
Vitamin B12 30mcg
Vitamin D2 6.25mcg 250iu




#1699 Pirate

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Posted 28 December 2012 - 05:10 AM

Is it recommended to take 400iu of Vitamin E with this stack? (and why?)

#1700 tea76

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Posted 31 December 2012 - 03:24 PM

Hi there,

Does anyone have purchasing suggestions for Uridine?
Either TAU or UMP - I am unsure which one gives best value.

PS: I live in the EU.

#1701 nupi

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Posted 31 December 2012 - 04:00 PM

TAU from iHerb (in capsules, so easier to handle) or UMP from Superior Nutraceuticals, they both ship to Europe for reasonable fees.

#1702 Hope47

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Posted 31 December 2012 - 05:34 PM

What is the difference between them(Tau and Uridine).

#1703 Adaptogen

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Posted 31 December 2012 - 07:22 PM

Tau is stronger orally,

but if you take uridine sublingually it is just as good and more cost effective, i think.

#1704 Adaptogen

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Posted 01 January 2013 - 10:56 PM

So I am currently taking 50mg uridine, 500mg alcar, fish oil, and a b vitamin every other day.

However, some of the doses in my b-complex seems to be a little high.


Posted Image

is 100mg b6 too much? Would i be better off cutting these in half?

Edited by Adaptogen, 01 January 2013 - 10:59 PM.


#1705 norepinephrine

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Posted 02 January 2013 - 11:49 PM

Started taking TAU around November/December, really didn't notice much.

Obtained some SN UMP more recently and I've been taking 250mg sublingually once a day (with omega 3's, eggs and B-vitamins of course). Coupled with daily aerobic exercise, I've noticed the following: increased recall, especially for random factoids, names and numbers; possibly increased working memory, but I'm taking other things to target that (creatine, herbs); flattened mood with too high of a dose, though nothing compared to what aniracetam and high amounts of piracetam did to me.

Overall, it's been a happy shift for me, although I really can't say if it was UMP or merely exercise that brought it on. Over the first half the year I was at the most sedentary I've been in years and became depressed and anxious, but moreso than that started forgetting names, numbers and factoids that were previously very easy to remember. As well, I'd actively struggle for words or get tongue-tied mid sentence searching for the right thing in my head. I attribute this either to too heavy of a chronic B6 dosage (which seemed to bring on neuropathy), as well as the lack of exercise; fortunately, the return of a healthy regimen and addition of UMP has really helped me in a way that the racetams did not, and in a way that ALCAR, choline and fish oil only slightly alleviated.

#1706 Guardian4981

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Posted 07 January 2013 - 09:21 PM

So after a hiatus for a couple weeks I will give an update of what is going on.


For the past year or so I have struggled with feeling light headed when standing which gets worse as the day goes on and after I eat. I also felt pins and needles the first few minutes of working out. When taking uridine or anything which helped serotonin I found this would get even worse.

After countless research and trial and error I feel I had a T3 deficiency. T3 can influence blood circulation be influencing blood volume and red blood cell size/shape. After a week of using 400 mcg selenium a day my symtoms are gone which I am very happy about. Now I do not feel light headed and when working out I have more energy with no pins and needles. More then likely the reason serotonin products made this issue worse is serotonin increases platelet aggregation, so if you have circulation problems from another underlying issue it will get worse since the blood is thicker.

The increased T3 has some benefit on my mood in that my body does not feel as tired and I wake up a bit more rested. However I can tell my mind is still not where I want to be, which suggested my ongoing battle with dysthmia/dep may have been influenced by low thyroid but is not solely because of it.

I am going to be starting gugglesterones today which is believed to also help the thyroid and conversion of T4 to T3. After another week or two of this I am likely going to re visit the uridine stack. Uridine killed the little libido I had, however the T3 seems to be boosting my libido.

I also am not entirely sure on the relationship between Uridine and thyroid/T3. Perhaps with more healthy thyroid and T3 the uridine will work better and not kill my libido.

So I am currently taking 50mg uridine, 500mg alcar, fish oil, and a b vitamin every other day.

However, some of the doses in my b-complex seems to be a little high.


Posted Image

is 100mg b6 too much? Would i be better off cutting these in half?



I would consider dropping the ALCAR. Research suggests carnitine may occupy thyroid receptors on cells. When I use any kind of carnitine I feel like a million bucks for a couple days then I slowly feel really letharigic and tired.

Also in terms of your B vitamin, I thinkt he form of B6 has a role. If I take pyrodixine HCL i get anxiety and numb extremeties. If I take the same dose of P-5-P I don't get these symptoms.

Either way I think most people should not take any more then 50 mg B6 a day, to me it seems to be the most dangerous B vitamin in terms of potential harm. Your multi/B vitamin as a whole seems cheap/lousy no offense, poor forms of every B vitamin.

Edited by Guardian4981, 07 January 2013 - 09:22 PM.


#1707 biggyrat

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Posted 08 January 2013 - 12:54 AM

Hello Everyone,

Usually I'm lurking about, but thought I would chime in a bit. I started taking Uridine a few days ago ( I think this is day 3). I purchased the powder form of UMP from Super Neutraceuticals. I also have Alpha GPC- taking 1 400mg cap ( NOW) per day. I have not been taking DHA so far. The UMP comes with a scoop, which full is supposed to be around 250mg. Day 1 I took about 3/4 scoop, yesterday 1 full scoop, today about 1/2 scoop. I take the powder sublingually, before eating, when I get up in the morning. The effect seems to come on in about an hour or so ( haven't kept track exactly), and I think it becomes more pronounced as the day goes along. By evening it seems to wear off. i also take Wellbutrin- a pretty small dose.

The first day I took it, it seemed amazing in that, it sort of calmed me down. Often I find that I don't concentrate well on anything that is stressful or difficult, that I flit from thing to thing, am scattered- trying to do too many things at once- never getting very far with one thing. So it seemed that UPM was really helping me with this. It seems to help me be more focused, not be so concerned with all the other things I need to do, while trying to do one thing, and , to some extent seems to make me feel less self conscious while speaking in a group ( this is often very difficult for me). The problem is that I go from my usual state of being too concerned with exterior issues ( what other peole think, everything else I need to get done, etc), to feeling calmer, more focused, more centered in myself, but then it gets too extreme, where I begin to feel very disconnected, alienated, very cut off, not feeling much for anyone else. It feels scary - not good. I thought that today, by taking about 1/2 scoop, I possibly woudln't experience the same disconnect, but unfortunatly this seems to be just as strong as before.

I wondered whether anyone else had experienced this. I don't know whether taking DHA would help. I sort of conflicted about taking fish oits. The issues with how polyunsaturated they are, the Weston A Price stance on them - they advocate the fermened cod liver oil, but I am wary of that as well- and the taste is hard to take. So this is why I have not taken the DHA.

I understand that the extra choline can contribute to depression ( I don't understand why that is so) which I have suffered from for much of my life, but I don't know if I can classify the feelings that I've been having as a result of taking UMP as depression exactly. At least its not a depression that I am familiar with. I mainly feel very detached, from people ( my daughter even) and just that things are bad somehow. I'm not sure how to describe it.

Thanks,

Sally
'

#1708 yoann_co

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Posted 08 January 2013 - 12:27 PM

Hi everybody,
G'day MrHappy,
Best wishes for 2013!

Are you aware of heavy metals poisoning? Especially from amalgams (dental fillings) and from vaccines.
I've been on this very good combo for a long time, and it was very helpful thank you. My cognitive problems were very improved but I was not fully healthy and not recovered (if I stop the combo all will be back).

So for me this combo is not the antidote that will cure the disease, also because I don't know what is my disease.

I had amalgams before (they have been removed), the mercury idea seems to be a strong hypothesis.
This went to my mind because I went on different french websites/forums (I'm french) where I could read similar experiences. All theses stories were pointing to mercury and amalgams.

I've done recently real medical analysis that confirm this, but I'm not 100% sure.

Mercury long time and low dose intoxication (such as amalgams) cannot be viewed by a standard blood analysis. With mercury intoxication most people feel very and long time tired and depressed. All of them went to many doctors but nobody know what they have, and most of doctors just answer "it's psychological". WRONG answer from all the testimonials I read, even if psychological factors are linked ok. Mercury enjoy to set himself to fatty parts of the body such as brain and intestines. For some people mercury is very difficult to eliminate naturally by there own body (genetics factors). Mercury may also be interfered with many other environmental diseases, such as lyme diseases etc.

I will start soon a chelation. There is many differents kinds, I would advise not to do any intravenous chelation, too risky.
I would advise to learn more about that by reading "Amalgam Illness" by Dr Cutler or other things from Dr klinghardt.
Also there is a french forum http://www.forum-melodie.fr, this forum will maybe nearly save my life...
A gluten free regimen is very helpful.

Feel free to find more about mercury and amalgams, or not. I just wanted to show something that might be in my case extremely helpful.
I will keep you informed if I will be recovered or not :) .

P.S : With all due respect, I remember MrHappy that if you stop the combo, all your problems will be back. So maybe you're not fully recovered yourself and maybe you are mercury intoxicated or have an environmental disease. Correct me if I'm wrong :).

Cheers

Yoann

Edited by yoann_co, 08 January 2013 - 12:30 PM.


#1709 MrHappy

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Posted 08 January 2013 - 07:58 PM

Hello Everyone,

Usually I'm lurking about, but thought I would chime in a bit. I started taking Uridine a few days ago ( I think this is day 3). I purchased the powder form of UMP from Super Neutraceuticals. I also have Alpha GPC- taking 1 400mg cap ( NOW) per day. I have not been taking DHA so far. The UMP comes with a scoop, which full is supposed to be around 250mg. Day 1 I took about 3/4 scoop, yesterday 1 full scoop, today about 1/2 scoop. I take the powder sublingually, before eating, when I get up in the morning. The effect seems to come on in about an hour or so ( haven't kept track exactly), and I think it becomes more pronounced as the day goes along. By evening it seems to wear off. i also take Wellbutrin- a pretty small dose.

The first day I took it, it seemed amazing in that, it sort of calmed me down. Often I find that I don't concentrate well on anything that is stressful or difficult, that I flit from thing to thing, am scattered- trying to do too many things at once- never getting very far with one thing. So it seemed that UPM was really helping me with this. It seems to help me be more focused, not be so concerned with all the other things I need to do, while trying to do one thing, and , to some extent seems to make me feel less self conscious while speaking in a group ( this is often very difficult for me). The problem is that I go from my usual state of being too concerned with exterior issues ( what other peole think, everything else I need to get done, etc), to feeling calmer, more focused, more centered in myself, but then it gets too extreme, where I begin to feel very disconnected, alienated, very cut off, not feeling much for anyone else. It feels scary - not good. I thought that today, by taking about 1/2 scoop, I possibly woudln't experience the same disconnect, but unfortunatly this seems to be just as strong as before.

I wondered whether anyone else had experienced this. I don't know whether taking DHA would help. I sort of conflicted about taking fish oits. The issues with how polyunsaturated they are, the Weston A Price stance on them - they advocate the fermened cod liver oil, but I am wary of that as well- and the taste is hard to take. So this is why I have not taken the DHA.

I understand that the extra choline can contribute to depression ( I don't understand why that is so) which I have suffered from for much of my life, but I don't know if I can classify the feelings that I've been having as a result of taking UMP as depression exactly. At least its not a depression that I am familiar with. I mainly feel very detached, from people ( my daughter even) and just that things are bad somehow. I'm not sure how to describe it.

Thanks,

Sally
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Hi Sally, try taking a full scoop, orally (not sublingually), twice per day and I think you'll be closer to your optimal dose. :)

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#1710 MrHappy

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Posted 08 January 2013 - 08:08 PM

Hi everybody,
G'day MrHappy,
Best wishes for 2013!

Are you aware of heavy metals poisoning? Especially from amalgams (dental fillings) and from vaccines.
I've been on this very good combo for a long time, and it was very helpful thank you. My cognitive problems were very improved but I was not fully healthy and not recovered (if I stop the combo all will be back).

So for me this combo is not the antidote that will cure the disease, also because I don't know what is my disease.

I had amalgams before (they have been removed), the mercury idea seems to be a strong hypothesis.
This went to my mind because I went on different french websites/forums (I'm french) where I could read similar experiences. All theses stories were pointing to mercury and amalgams.

I've done recently real medical analysis that confirm this, but I'm not 100% sure.

Mercury long time and low dose intoxication (such as amalgams) cannot be viewed by a standard blood analysis. With mercury intoxication most people feel very and long time tired and depressed. All of them went to many doctors but nobody know what they have, and most of doctors just answer "it's psychological". WRONG answer from all the testimonials I read, even if psychological factors are linked ok. Mercury enjoy to set himself to fatty parts of the body such as brain and intestines. For some people mercury is very difficult to eliminate naturally by there own body (genetics factors). Mercury may also be interfered with many other environmental diseases, such as lyme diseases etc.

I will start soon a chelation. There is many differents kinds, I would advise not to do any intravenous chelation, too risky.
I would advise to learn more about that by reading "Amalgam Illness" by Dr Cutler or other things from Dr klinghardt.
Also there is a french forum http://www.forum-melodie.fr, this forum will maybe nearly save my life...
A gluten free regimen is very helpful.

Feel free to find more about mercury and amalgams, or not. I just wanted to show something that might be in my case extremely helpful.
I will keep you informed if I will be recovered or not :) .

P.S : With all due respect, I remember MrHappy that if you stop the combo, all your problems will be back. So maybe you're not fully recovered yourself and maybe you are mercury intoxicated or have an environmental disease. Correct me if I'm wrong :).

Cheers

Yoann

Hi Yoann,
In my case, my environmental factors are the major cause, although there is a long family history of depression. If I wasn't working consistently long hours under (usually) very high pressure, my normal diet would sustain my health/happiness.

I'm also lucky in that I have no dental fillings, but one of these days, I'll probably do a hair test just to see if there is anything I should look at - although, I do eat spirulina almost daily, which does act as a chelator.

Let me know how you go. :)





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