2844 replies to this topic

[Nickotin]

Has anyone tried the UMP from smart powders (smartpowders.com)? I received mine yesterday and it is substantially different from the ecological formulas UMP. Both the taste and the texture are different (bulk powder is almost the consistency of flour). I also have noticed that it's giving me a bit of brain fog and flattening of mood in comparison to the ecological formulas UMP. I've been taking the EF caps and taking half sublingually up to 3 times a day and had great results up until now. I'm not getting the same mood and cognitive benefits from the powder, and while I realize that I need to back off the dose, I'm wonder what experience others have had with it.

[DamnedOwl]

I ordered some from Smart Powders the other week, once it arrives I'll let you know.

[alecnevsky]

Smart powders used to have 99% alpha gpc which was great (this was October last year.) Now they sell "50%" AGPC that tastes like complete shit and I am confident the rest of their stock is shit quality at best. They never attach COA even if you explicitly ask them. They ship from NC and prob have super lax regulations there. I'd buy everything from California if I could find a store.

Moral of the story: I've been buying from them on an off for a year and I don't trust them. They seem to cater to complete uninformed idiots --which is prob just a reflection of management's business acumen and intellect.

Edited by alecnevsky, 21 May 2013 - 08:00 PM.

[hani]

Smart powders used to have 99% alpha gpc which was great (this was October last year.) Now they sell "50%" AGPC that tastes like complete shit and I am confident the rest of their stock is shit quality at best. They never attach COA even if you explicitly ask them. They ship from NC and prob have super lax regulations there. I'd buy everything from California if I could find a store.

Moral of the story: I've been buying from them on an off for a year and I don't trust them. They seem to cater to complete uninformed idiots --which is prob just a reflection of management's business acumen and intellect.

Damn.. I hope the Uridine I ordered will be OK.

[chris106]

I've been following this thread for some time, but it was sort of useless as sourcing uridine in the UK was difficult for me.

I've been pestering my usual supplier (JG) to try and stock it (apparently some others have as well) - today I got an email saying they've got it.

link: http://www.jgsupplements.com/uridine/

Polymathic - you're the man!

Seriously though, this is great news for me. I live in germany and had the same problem. I have been hesitant to try the uridine stack due to financial reasons, and while the uridine offered at jg still isn't cheap, at least now I don't have to pay that much for shipping costs, and can also be sure it will arrive somewhat fast.

So thanks for your efforts!

[Judd Crane]

I'm wondering what people think of the vasodilation properties of uridine. How does it compare to vinpocetine or ginkgo biloba?

[karoshi]

Has anyone tried the UMP from smart powders (smartpowders.com)? I received mine yesterday and it is substantially different from the ecological formulas UMP. Both the taste and the texture are different (bulk powder is almost the consistency of flour). I also have noticed that it's giving me a bit of brain fog and flattening of mood in comparison to the ecological formulas UMP. I've been taking the EF caps and taking half sublingually up to 3 times a day and had great results up until now. I'm not getting the same mood and cognitive benefits from the powder, and while I realize that I need to back off the dose, I'm wonder what experience others have had with it.

Hmm... I'm intertested in their Uridine. That's sad.
I have been using him for 5-6years occasionally. In my experience, their former shop was good source of nootropics. Smartpowders was good too for me.
I have not placed an order for several months. What's going on with him?

[Nickotin]

Has anyone tried the UMP from smart powders (smartpowders.com)? I received mine yesterday and it is substantially different from the ecological formulas UMP. Both the taste and the texture are different (bulk powder is almost the consistency of flour). I also have noticed that it's giving me a bit of brain fog and flattening of mood in comparison to the ecological formulas UMP. I've been taking the EF caps and taking half sublingually up to 3 times a day and had great results up until now. I'm not getting the same mood and cognitive benefits from the powder, and while I realize that I need to back off the dose, I'm wonder what experience others have had with it.

Hmm... I'm intertested in their Uridine. That's sad.
I have been using him for 5-6years occasionally. In my experience, their former shop was good source of nootropics. Smartpowders was good too for me.
I have not placed an order for several months. What's going on with him?

I'm honestly not sure what bulk powder UMP is supposed to look and taste like. I was used to sublingual dosing UMP @ 1/3 - 1/2 of a 300mg cap TID. I know that these caps also contain fillers that would change the taste and volume. I'm going to try to take micro doses of the SP UMP to see if it is just stronger than I'm used to. I don't want to hurt anyone's business if I'm wrong about it... I was hoping to see if anyone else had any experience with smartpowders UMP.

[bobz1lla]

You kind of get what you pay for.

You might want to give SN a try. People have had success with them earlier in the thread.

[flurr]

So i've been on the stack for a month, maybe some more, now im beginning to experience headaches. Anyone got a similiar problem? A nagging feeling which is pretty harsh, leaves me unfocused and sort of brain fogged for half of the day. Have to quit the stack if this persists.

Currently taking around 150-250 UMP just once per day (switching between sublingual and oral) with all the co-factors.

Lately i've begun consuming a bit more caffeine throughout the day though which could be a part of the issue (basically cut it out on the start of this stack), however, im just drinking one cup of coffee plus maybe 2 cups of tea max. Could this be the case? I do not feel any potentiating effects of the caffeine, just need it some mornings when i've slept really bad.

[alecnevsky]

So i've been on the stack for a month, maybe some more, now im beginning to experience headaches. Anyone got a similiar problem? A nagging feeling which is pretty harsh, leaves me unfocused and sort of brain fogged for half of the day. Have to quit the stack if this persists.

Currently taking around 150-250 UMP just once per day (switching between sublingual and oral) with all the co-factors.

Lately i've begun consuming a bit more caffeine throughout the day though which could be a part of the issue (basically cut it out on the start of this stack), however, im just drinking one cup of coffee plus maybe 2 cups of tea max. Could this be the case? I do not feel any potentiating effects of the caffeine, just need it some mornings when i've slept really bad.

The coffee/tea/yerba mate whatever is pretty much bad with all: modafinil, armodafinil, uridine. Definitely cut it.

BTW., I just dosed 350mg UMP + 50mg Sunifiram. No immediate side effects. #4sakeofscience

Edited by alecnevsky, 25 May 2013 - 05:49 PM.

[Chadwick]

Through which mechanisms do uridine upregulate dopamine receptors? I'm curious because I get great effects from uridine but build tolerance to it in about two weeks. I've used it during a few periods the last year and the pattern is consistent. It's almost as if I get the dopamine release but without receptor upregulation.

I'm currently also on ~600 mg DHA, ~900 mg EPA, 25 mg zinc, 500 mg ALCAR, 5000 iu vitamin D and a B complex every day. I'm not consuming caffeine or any other stimulants.

I have a similar problem with this stack being apparently less effective after a while, and so I'm currently trying to tweak the amounts I take in order to get something more stable.

I have only found that taking tyrosine before the uridine to make a difference so far. If I don't take tyrosine or if I take it after the uridine then I either don't get any kind of noticeable effect from this stack, or I even get a slight brain fog.

Do you take the uridine orally or sublingually? I've only been taking it sublingually so far at single doses of either 75, 100, or 150mg twice a day. Given the supposed increase in potency of the sublingual route, all of these doses could be said to be on the high side, so my next course of action will be to either take the uridine orally or just take smaller amounts sublingually. I notice that vitamin E is also missing from your list.

Also, have you tried to different DHA:EPA ratios? The Souvenaid formula, for example, has a 4:1 (DHA:EPA) ratio. Maybe this would make a difference. It's something I'm also considering tweaking anyway because my DHA:EPA ratio is 1:2. Still, some will say the ratio balance isn't particularly important.

I'm taking 150 mg sublingually two times a day. I also get good effects from tyrosine before UMP (haven't tried taking it after) but after a few days of use I develop extreme tiredness lasting 5-6 h after a dose. I have no idea why.

I have used vitamin E in combo with the stack in the past, but without effect. I don't really believe it's needed though - it was recommended in this thread because it was included in a patent, but I'm asuming that was because it's often included in fish oil supplements to prevent oxidation of the fats. I have also only tried a 1:2 ratio of DHA and EPA, so maybe that's something to play around with

[DamnedOwl]

Through which mechanisms do uridine upregulate dopamine receptors? I'm curious because I get great effects from uridine but build tolerance to it in about two weeks. I've used it during a few periods the last year and the pattern is consistent. It's almost as if I get the dopamine release but without receptor upregulation.

I'm currently also on ~600 mg DHA, ~900 mg EPA, 25 mg zinc, 500 mg ALCAR, 5000 iu vitamin D and a B complex every day. I'm not consuming caffeine or any other stimulants.

I have a similar problem with this stack being apparently less effective after a while, and so I'm currently trying to tweak the amounts I take in order to get something more stable.

I have only found that taking tyrosine before the uridine to make a difference so far. If I don't take tyrosine or if I take it after the uridine then I either don't get any kind of noticeable effect from this stack, or I even get a slight brain fog.

Do you take the uridine orally or sublingually? I've only been taking it sublingually so far at single doses of either 75, 100, or 150mg twice a day. Given the supposed increase in potency of the sublingual route, all of these doses could be said to be on the high side, so my next course of action will be to either take the uridine orally or just take smaller amounts sublingually. I notice that vitamin E is also missing from your list.

Also, have you tried to different DHA:EPA ratios? The Souvenaid formula, for example, has a 4:1 (DHA:EPA) ratio. Maybe this would make a difference. It's something I'm also considering tweaking anyway because my DHA:EPA ratio is 1:2. Still, some will say the ratio balance isn't particularly important.

I'm taking 150 mg sublingually two times a day. I also get good effects from tyrosine before UMP (haven't tried taking it after) but after a few days of use I develop extreme tiredness lasting 5-6 h after a dose. I have no idea why.

I have used vitamin E in combo with the stack in the past, but without effect. I don't really believe it's needed though - it was recommended in this thread because it was included in a patent, but I'm asuming that was because it's often included in fish oil supplements to prevent oxidation of the fats. I have also only tried a 1:2 ratio of DHA and EPA, so maybe that's something to play around with

The last couple of weeks I've limited the UMP to 100mg sublingually twice a day, and this seems to be stable with consistently appreciable effects from the stack.

By the way, I also got the heavy tiredness when taking 150mg sublingually twice a day, which was puzzling but also frustrating too because the first few days at 150mg were excellent.

[chemicalambrosia]

I'm taking 150 mg sublingually two times a day. I also get good effects from tyrosine before UMP (haven't tried taking it after) but after a few days of use I develop extreme tiredness lasting 5-6 h after a dose. I have no idea why.

I have used vitamin E in combo with the stack in the past, but without effect. I don't really believe it's needed though - it was recommended in this thread because it was included in a patent, but I'm asuming that was because it's often included in fish oil supplements to prevent oxidation of the fats. I have also only tried a 1:2 ratio of DHA and EPA, so maybe that's something to play around with

I agree on the Vitamin E. I'm far from an expert on any of this, but I don't remember Vitamin E being in the studies that I read on uridine, and don't know of how it would be a co-factor. Also, there have been studies that show negative results for high dose vitamin E. I personally dropped extra Vitamin E supplementation and think that maybe Mr. Happy should drop it from the first page, or at least add a caveat to it. I do take toco-sorb though...

Anyways, I have been taking uridine for quite some time now. I am about to start on the second Superior Nutraceuticals tub of uridine UMP. I've been taking about 100-200 mg sublingually each morning and have seemingly gotten good results in mood, sense of well-being, motivation, ability to deal with stress, and possibly clearer thinking. This is all pretty subjective, as everyone goes through cyclical ups and downs, but at this point I would say uridine is a must try supplement. Interestingly I had some bowel disturbances(possibly due to mixing with coffee) the very first few days I tried it, and also some long lingering headaches. At one point with the headaches it seemed like I felt great, despite a headache. It was strange, but this is one of the few supplements that I would recommend trying to "tough it out" if you have a headaches as a side effect. IIRC the headaches were gone after a few days and never came back.

Thank you Mr. Happy and all the others for bringing uridine into the light. I think someday it will be as popular and ubiquitous as fish oil or vitamin C and probably help a lot of people.

Edited by chemicalambrosia, 27 May 2013 - 06:23 PM.

[hani]

I just got my Uridine from smartpowders. I must say, the taste is completely different than the Ecological forumla, but I know that the EF brand has some filler in it.

For those that have the Super Nautical bulk powder. what does the Uridine taste like?

[Nickotin]

I just got my Uridine from smartpowders. I must say, the taste is completely different than the Ecological forumla, but I know that the EF brand has some filler in it.

For those that have the Super Nautical bulk powder. what does the Uridine taste like?

+1

Funny, I posted this exact thing a page back or so. I'm realizing that someone with previous bulk supply likely wouldn't have reordered so quickly...and it's a new product from smart powders couple. If someone has super nutraceuticals powder and lives in the u.s. then pm me and I'll vacuum seal and ship you a couple grams for comparison. I went back to e.f. until I see some more feedback on the s.p. uridine.

Sent from my Galaxy Nexus using Tapatalk 2

Edited by Nickotin, 28 May 2013 - 08:46 PM.

[Hebbeh]

I'm on my third batch of UMP from Superior Nutraceuticals. The first batch was a little more granular like maybe table salt or sugar and had a just a slight hint of saltiness but other than that, fairly tasteless. The last couple batches seemed a little finer in texture and the hint of saltiness seemed less evident....but maybe I just got used to it. Regardless, it's mostly tasteless with no discernible smell.

I got a quote for a kilo of free base uridine from a lab in China but ran into difficulties with my bank not supporting TT transfer to the bank in China and therefor ordered the last batch of UMP from SN right before I saw Smart Powders was carrying it (cheaper).

My understanding with free base Uridine, is that it has a stronger taste and possible smell. More of a sour taste rather than slightly salty. But it is supposed to work as well or possibly better than UMP. I wonder if Smart Powders has UMP or free base?

[hani]

It does have a sour taste, could it be free base? Anyways, I will send an email to SmartPowders maybe they can provide us with a certificate of analysis. There are plenty of potential customers for Uridine on this thread, so maybe they'll reply.

[hani]

By the way, I just noticed that the powder packet doesn't specify the molecular structure of Uridine (UMP or otherwise), it just says Uridine 30grams.

[hani]

I sent a link to the thread to SmartPowders. This is their reply about the Uridine:

I read the thread. Its funny that how ppl assume that because your cheaper, it must be bunk material.

They also attached a COA.

Concerning the Alpha GPC:

If you will, please inform people that the reason we don't carry the 99% Alpha GPC anymore is because we can't find a stable 99% powder that doesn't turn into liquid. Even if 10% of te powder turns to liquid, it will ruin the rest of the powder. We lucked out and found 1 source that had amazing 99% that was stable, but we can't find any that is stable right now at 99%. So that is the REASON we sell 50%. The negative response of customers getting Luiquified alpha gpc was much higher than the positive who preferred it.

So I guess this settles it then.

Attached Files

•  Uridine COA_002.jpg   56.82KB   49 downloads

[Nickotin]

I'm always a bit skeptical about mfg coa. The description says "crystalline powder" which would describe other uridine, but sp uridine is like moist flour. It is most definitely stronger OR different than UMP, IMO.

Sent from my Galaxy Nexus using Tapatalk 2

[hani]

Maybe it's free base (whatever that is), like the one people are ordering from China.

[hani]

I must say SP Uridine dissolves much better sublingually then ecological formulas.

[spookytooth]

So does SP Udirine work as well as UMP from other sources?

[alecnevsky]

Great to know my caustic internet ramblings were actually perused by the management. STOCK 99% GPC. I HAVE A FRIDGE. lol

[Karmakenic]

Does anyone stack this with the ciltep stack? Say ciltep morning uridine at night?

[alecnevsky]

Does anyone stack this with the ciltep stack? Say ciltep morning uridine at night?

I did that before. It works, although I used TAU + Ani.

Btw., my AGPC from smart powders turned into clumps of white crap (2 months old at most.) It tastes like shit.

Edited by alecnevsky, 31 May 2013 - 01:04 PM.

[owtsgmi]

Does anyone stack this with the ciltep stack? Say ciltep morning uridine at night?

Yep. Both in the am only.

[prunk]

Does anyone stack this with the ciltep stack? Say ciltep morning uridine at night?

Yep. Both in the am only.

Have you noticed any issues with working memory while on both?

[MrHappy]

Hey all, sorry for the absence - my first little daughter arrived into this world about 2 weeks back.

As mentioned previously, I have been studying the effects of enhanced nutrition on gestation and early childhood development, based around a slightly modified version of the uridine protocol. There are already exciting results, but I'm going to be keeping a separate online journal of the progress.

I can also attest to the efficacy of uridine (anecdotal, n=1) in treating 'baby blues' and post-natal depression. This adds some weight to my hypothesis that some causes of PND (affecting 1 in 7 women) are related to the mother's body selflessly prioritising the allocation of micro-nutrients to breast-milk, instead of the mother's other biological functions and can be easily corrected by appropriate supplementation of the uridine stack. Sleep quality is also a major factor, also helped by the same.

I'll post a link here to the online journal, once I've started it, for anyone interested in generational trans-humanism.

 ImageUploadedByTapatalk1370077329.750408.jpg   23.12KB   47 downloads

As an early indication, here's a picture of a (3 week early birth) 7 day old holding a bottle of her mother's breast-milk, by her own choice.