13 replies to this topic

[MrHappy]

Anyone else thought about this? I came across it while looking for easier sources of uridine for the a-GPC, Uridine, DHA stack.

Look at the contents - the only thing I'm not sure on is the quantities of each ingredient. Does anyone have one of these containers at home with hopefully the full ingredient specs?
AU$30 gets you 900g. Just add Alpha-GPC and

Product Information

S-26 PROGRESS GOLD, with the Wyeth Biofactors System, is a premium follow-on formula that provides advanced nutrition through its unique combination of nutrients, meeting the needs of this stage of rapid growth and development. S-26 PROGRESS GOLD is casein dominant.

* Omega 3: to help support brain and eye development
* Nucleotides: to help support immunity
* Iron: to help support growth

Ingredients
Non-fat milk powder; lactose; vegetable oils [palm, coconut, oleic (safflower or sunflower), soybean]; emulsifiers (soy lecithin, monoglycerides); long chain polyunsaturated fatty acids from single-cell sources [arachidonic acid (AA) docosahexaenoic acid (DHA)]; L-cysteine; taurine; nucleotides (cytidine -5'-monophosphate; disodium uridine 5'-monophosphate, adenosine-5'-monophosphate; disodium inosine-5'-monophosphate; disodium guanosine-5'-monophosphate); antioxidant (mixed tocopherols concentrate, ascorbyl palmitate).

Minerals
Sodium citrate; calcium carbonate; calcium hydroxide; potassium bicorbonate; magnesium carbonate; ferrous sulphate; Zinc sulphate; copper sulphate; manganese sulphate; potassium iodide; sodium selenite.

Vitamins
Vitamin C; vitamin E; niacin; vitamin A; calcium pantothenate; vitamin B1; vitamin B6; vitamin D3; vitamin B2; natural carotenes; folic acid; vitamin K; biotin; vitamin B12.

S-26 PROGRESS GOLD protein source is non-fat milk. Contains milk and soy lecithin.

[QuantumTubule]

umm yes nice supplements however have you considered that most of your diet would need to be compsed of the stuff to get the Rec Dosage.
I would drop all supplements before living off poweredised milk, lactose and refined oil.Infants have startling different psyology btw. there what is ok for them may not be for an adult. Im not going to call it a nootropic

[MrHappy]

Ahh.. so you have a list of the individual quantities? I'd be curious how much uridine is in it.

There is also the LF (lactose free) version which doesn't have bovine / whey.

[chrono]

I couldn't find any better info about the specific quantities, and forms of the vitamins. My guess would be that a formula designed for infants would probably not be that valuable for adults. And I think calling it an all-in-one noot is a bit of a stretch, since the ingredients really aren't going to impact cognition any more than a good multivitamin.

[MrHappy]

Multivitamin + Multimineral (always a good idea)

+

DHA
Choline (lecithin)
Uridine

See this: http://www.smart-pub...nst-Alzheimers/
That looks pretty nootpropic to me, if the quantities are high enough.

[chrono]

I suppose it just depends on what one means by "all-in-one noot." To me, this description implies significant (or at least noticeable) cognitive enhancement for a significant amount of the people who take it. I think that a poorly-designed multivitamin with a few micronutrients, and DHA/lecithin/uridine, is unlikely to produce any effects in the vast majority of people who try it. These ingredients could improve long-term brain health, but I think an all-in-one noot would have a much more unambiguous impact on cognition.

[MrHappy]

Speaking as someone who is currently taking 20-50mcg of MB, 500mg of a-gpc, 150mg of uridine and 3 caps of flaxseed oil, per day, I'd have to disagree with you about the benefits.

So far, this is my favourite stack - clear headed, happy, easier recall and not in the least 'buzzy'.

There's no up and down effect, but I do seem to need a lot more water.

Theory is that some of these improvements should also be semi-permanent - the additional neurons and dendrites, at least. The increased PC levels will be dose related, though.

I really need to find out the ingredient quantities in S-26 to see if it is a viable option. It wouldn't be hard to use this as a meal replacement for either breakfast or lunch, if it is.

[chrono]

Speaking as someone who is currently taking 20-50mcg of MB, 500mg of a-gpc, 150mg of uridine and 3 caps of flaxseed oil, per day, I'd have to disagree with you about the benefits.

I think it would be impossible to find anyone suggesting that a large dose of alpha-gpc and any amount of lecithin have similar nootropic properties. And that's where 95% of the effect of your stack is coming from, I would wager (that and MB).

I feel like this is a semantic argument. If you want to consider something like this an all-in-one nootropic because it shares a few basic neurogenic/protective chemicals with your stack, I guess I'll just accept that I have vastly different criteria for that kind of claim.

[MrHappy]

I did say 'just add alpha gpc'..

[chrono]

Frankly, the addition of a cholinergic which happens to work for you wouldn't bring this any closer to realizing the term in question, at least by my definition. Your stack is not ideal (or even tolerable) for everyone, which I feel might be a necessary assumption for the question in the title to be true.

I guess what I'm trying to convey is that it's a very strange claim to make about baby formula, and IMO is not a reasonable description by any stretch, even if taking large amounts of it is somehow suitable for adults. The vitamins are not the best forms, so their presence is not necessarily beneficial at all. There are many combination products which are better, and the vast majority of those are inferior to even a basic stack of individual components, if well-designed.

Edited by chrono, 14 October 2011 - 12:14 AM.

[MrHappy]

Ahhh! Now I get you.

I haven't looked close enough to see which versions of eg. B12 are being used and I still don't know individual quantities of ingredients. I do know that I don't like calcium carbonate, so it'll depend on the levels to see if it's worth exploring.

Edited by MrHappy, 14 October 2011 - 08:11 AM.

[MrHappy]

I finally found the nutritional info and you'd need way too much. Some of the contents are counter productive. It's a fail. I don't think I'd even feed this to my kid, to be frank!

[QuantumTubule]

I definitly wouldnt be taking uridine without methylfolate, can you say genotoxic..... High levels of uridine compared to thymine cause the incorporation of uridine into DNA, this destablise the DNA inhibiting proper functioning. Methylfolate, methylates uridine to thymine, i suggest methylfolate as folate supplementation is ineffective at raising the biologically active methylfolate in over half the population.

More recently, uracil incorporation into DNA of folate-deficient HL-60 cells and lymphocytes was reported (Wickramasinghe and Fida 1993). Increased dUTP/dTTP ratios delayed progression of the DNA replication fork (Wickramasinghe and Hoffbrand 1980) and passage of cells through the cell cycle (James et al. 1994) and promoted genomic instability (Pogribny et al. 1995). In vitro studies demonstrated that increased dUTP/dTTP ratios promoted folate fragile site expression (Reidy 1987), DNA strand breaks (Li and Kaminskas 1984), error-prone DNA repair (Holliday 1985) and mutagenesis (Mattano et al. 1990). The role of folate deficiency in DNA damage was reviewed recently (Blout and Ames 1995).
Further evidence that an imbalance in nucleotide pools, specifically an increase in dUTP, is tumorigenic comes from studies indicating that an excess of dietary orotic acid, a precursor for uracil, promotes carcinogenesis in liver (Rao et al. 1983), mammary gland (Elliot and Visek 1989) and duodenum

Uridine does look interesting as a nootropic, were did you get your uridine? Why not taking a large dose of Brewers yeast?

[MrHappy]

I'm not fond of ingesting that much yeast.. as a vegetarian, yeast issues are already a problem.
I was considering tomatoes, though. 1Kg of tomatoes = 1g of uridine.



I found 25g of uridine on ebay for $50. Likewise, 50g of alpha-gpc for $50.