I started my little experiment with piracetam near the beginning of September, so three months have passed, and I've had time to observe its initial and on-going effects. For those with a voyeuristic bent, for those wishing to compare their own experience with someone else's, for those considering tinkering with their neurotransmitters and supporting wetware for the first time, or for those merely bored and curious, I've jotted down a few observations for your idle entertainment.
Me?
Male, early 50s, no ADHD or ADD or other cognitive kinks, no major psychosocial challenges, a rather high but not an OMG!-freaky-high IQ, multiple university degrees, and a job requiring constant mental exercise (I'm a reference and research librarian). Healthy so far, and about 90 kg. Currently, exercise is a brisk 25 minute walk to, and from work, and lots of prostrations during my ngondro practice. A long-time practitioner of shamata, vipassana, and other Buddhist meditation techniques. A total homosexual. Left-handed. Get between 8-9 hours sleep a night. No notable decline of cognitive faculties (yet). Content, or about as content as a smart, well-educated, and successful professional can expect to be in today's mad world.
Why experiment with piracetam (and, hopefully, other nootropics)?
Errr...why not? I'm a grown-up.
My "youthful" experiments with alcohol, pot, LSD, shrooms, and cocaine were very moderate and didn't begin until my late 20s...by which time my brain had settled down into, ahem, "comfortable middle age". I had no bad experiences, and no addictions came of them. Pot even took the uncomfortably sharp edge off a razor-keen memory that was proving to be more of a social liability than a personal asset.
How'd I do it?
First, I read a lot to familiarize myself with the territory.
I started with an attack dose of 2400 mg piracetam morning, noon, and afternoon (total 7200 mg/day) plus 1000 mg of alpha-gpc in the morning. This for three days, then a drop in piracetam to 1800 mg/dose (x3 = 5400 mg/day) for another three days, and a further reduction to 1200 for another three days (x3 = 3600 mg/day), finishing with a on-going, maintenance dose of 600 mg three times daily (1800 mg/day). I dropped the alpha-gpc to just 250 mg in the morning after the first couple of days, as it seemed to boost my libido a bit more than I appreciated. No headaches at all.
Related to, but not part of the experiment—I also take 4.5 gm/day fish oil, a B-complex, CoQ10 and reservatrol, 4 gm vitamin C, 4000 IU vitamin D, 81 mg ASA, and a multivitamin.
The effects?
The attack phase was very exciting, with a noticeable boost in my perceptual field within one hour: colour saturation up... sound perception up... the whole sensorium turned up a notch or two. There was also a background elation/euphoria, almost as if I were expecting something amazing to happen at any second. (It didn't.) I'm not keen on feeling drugged unless I deliberately want to feel drugged, so the initial, non-stop ZOOM!!! was annoying, and I was happy reducing the dose to an almost subliminal level. I want to feel like I'm me...not like I'm a piracetam side-effect. And, frankly, the cautionary example of at least one former poster who gobbled it like candy has made me conscious of the seductions of hypomania. I don't want to feel like I'm a superior being (at least no more so than I am already prone to do).
At 1800 mg/day my perceptions are still subtly cranked, but not distracting so, save for the red taillights of vehicles at night. That particular spectral range seems supercharged. Sensitivity to the human vocal range is up, to the point that voices on the telephone are almost painfully loud. Taste and smell seem unaffected, as is touch...with one (major?) exception: there's a tiny, tiny bit of orgasmic anhedonia. It's barely noticeable, but unmistakeable.
My mood is relatively unaffected, maybe lighter, with a slight increase in my ambient sense of humour... not quite like smoking a joint, but not unlike it either. Again, subtle. Laughter comes more easily.
The most unsubtle effects have been aesthetic. The range of men I find attractive has exploded ridiculously, absurdly. The effect is not at all unpleasant, just bemusing. This extends beyond to the whole environment, which is somehow more "painterly" to my eye. Maybe a result of increased communication between the brain's hemispheres? How far this aesthetic change extends breached my awareness a couple of weeks ago when I looked in the mirror and realized that my body dismorphia had completely vanished (omg...who is that hot man in the mirror...omg it's me).
Music, too, is affected. The beauty of Dead Can Dance has reached points where I'm pulled into an aesthetic trance almost against my will.
Typing speed is up. Verbal fluency is up. Creativity is up, with solutions to persistent issues at work becoming evident using tools that were there all along, but never considered. Physical activity is up (why take the elevator when those stairs are screaming to be used?). Memory has improved, both short- and long-term, but not alarmingly so. (Backstory: I tried 5 mg/day of Aricept a while back, and found it very, very harsh. Memory became insanely acute, to the point that I dared not look at any licence plates lest I remember them all. Very unpleasant. That experiment ended after a couple of weeks.)
Piracetam has been anxiolytic for me, not that I'm anxiety-prone anyhow (I love playing to an audience).
Dreams are a bit more vivid, but not unpleasantly so.
Alcohol now gets me drunker faster, so it's only two beer out with friends instead of three. (Nice way to save money.) Weirdly, my physical coordination doesn't suffer as much even when drunk.
All in all, the effect has been a subtle boost verging on the subliminal, which is exactly what I had hoped for. The effects have "normalized", becoming commonplace and part of my background consciousness, again something had I hoped for, as the thought of permanently feeling WOW!!! creeps me out.
I can see why some people report that the "magic went away". I can't report that yet, but have very little desire to feel like a cognitive wizard every day, in any case.
Ethics?
Tough question. I'm a bad Buddhist (oh well...shrug) as I indulge in occasional intoxication. Does something which increases attention, alertness, creativity, etc. count as an intoxicant? Caffeine, the common nootropic agent of billions, finds its way into the teacup of every Buddhist teacher I've encountered, so there's at least some latitude in the tradition. I haven't figured this one out yet.
Next...?
A reduction in dosage, perhaps. Certainly less in total per day (probably down to 1600 mg from 1800), but split into two 800 mg doses, one morning and one noon-time. I hope this doesn't increase transitory background euphoria too much.
A bag of aniracetam and pramiracetam are sitting on the shelf whispering, "Try me...try me..." I shall, but becoming a know-it-all memory sponge again just doesn't attract me. I would truly hate hyperthymesia, even if pharmacologically induced.
But, all in all, it has been an excellent experience that I see no reason to put the brakes on.