223 replies to this topic

[fntms]

I have the impression magLT also has pretty strong systematic effects, such as an anticoagulant action (more so than mag glycinate in my experience, I get bad acid reflux with MagLT which I never get with the other mag form. )

[mangalorecafe]

 

So intravenous MgSO4 performs equally well as oral MgT?

MAGNESIUM SULFATE will perform equally well as MAGNESIUM L-THREONATE taken PER ORALLY whether it is adminstered via IV or IM INJECTION, or TRANSDERMALLY (e.g. by soaking for 12+ minutes in a hot bath into which 1-2 cups EPSOM SALTS are dissolved)

With regards to how MAGNESIUM SULFATE taken PER ORALLY compares to MAGNESIUM L-THREONATE taken PER ORALLY, that would depend upon the respective BIOAVAILABILITIES; however, even if MAGNESIUM SULFATE were proven to be lower in BIOAVAILABILITY than MAGNESIUM L-THREONATE, it will still be considerably more economically to simply take whatever higher dosage of MAGNESIUM SULFATE yields equivalent absorption to the MAGNESIUM L-THREONATE

Therefore, MAGNESIUM SULFATE will in fact be the preferred choice over MAGNESIUM L-THREONATE whatever the administration method

 

 

Magnesium Sulfate in Oral form is laxative. What I believe the advantage in Taking MgT is that it does not give you a laxative effect so you can take a lot more orally. a pill of MagT gives around 144 mg of magnesium. That is not only much more than MgCl but it works out the same. I did not want to spend more money on MagT so I bough MagCL liquid(filler free so ) and I can't tkae above one serving or I get loose motions. If you don't take it without and acid your stomach just bloats and I get only 66mg of Magnesium.
AFAIR MgSO5 contains less Magnesium than MagCl, Do correct me if I am wrong.
So if the effect is the same isnt better to take MagT Orally.

MgSO4 is very cheap but how much can we asborb transdermally, maybe if anyone has the information please share it so we can do a cost analysis. WOuld soaking in a tub of MagSO4 be cheaper or just popping in a MagT pill.

 

[Heisok]

A comment about Magnesium L-Threonate: It takes 2 gms or 3 capsules to get 144 mgs Magnesium. Generally the capsules are 667mg total per.The selling point for the Magnesium L-Threonate is that a higher percentage may cross into the brain. 

 

For cramping in my legs, I had limited success over the last 2 years using various quantities and types of Magnesium, in addition to other electrolytes. Nothing completely eliminated the nighttime cramps. I could not sleep on my back at all as the cramping would start. This included Epsom salts (Magnesium Sulfate) baths and long floats in Magnesium saturated isolation float tanks.

 

I am a little over 2 weeks into trying Magnesium Bisglycinate Chelate 3 times a day in addition to Magnesium from a multi nutrient vitamin style supplement which I have taken for years.

 

I have had no cramping at night, and I can sleep on my back.  I am keeping my fingers crossed that it continues. Large doses of DiMagnesium Malate, 1.5 gms per day of elemental Magnesium had partial improvement as did another Magnesium at 1.5 gms elemental Magnesium per day.

 

 

 

 

So intravenous MgSO4 performs equally well as oral MgT?

MAGNESIUM SULFATE will perform equally well as MAGNESIUM L-THREONATE taken PER ORALLY whether it is adminstered via IV or IM INJECTION, or TRANSDERMALLY (e.g. by soaking for 12+ minutes in a hot bath into which 1-2 cups EPSOM SALTS are dissolved)

With regards to how MAGNESIUM SULFATE taken PER ORALLY compares to MAGNESIUM L-THREONATE taken PER ORALLY, that would depend upon the respective BIOAVAILABILITIES; however, even if MAGNESIUM SULFATE were proven to be lower in BIOAVAILABILITY than MAGNESIUM L-THREONATE, it will still be considerably more economically to simply take whatever higher dosage of MAGNESIUM SULFATE yields equivalent absorption to the MAGNESIUM L-THREONATE

Therefore, MAGNESIUM SULFATE will in fact be the preferred choice over MAGNESIUM L-THREONATE whatever the administration method

 

 

Magnesium Sulfate in Oral form is laxative. What I believe the advantage in Taking MgT is that it does not give you a laxative effect so you can take a lot more orally. a pill of MagT gives around 144 mg of magnesium. That is not only much more than MgCl but it works out the same. I did not want to spend more money on MagT so I bough MagCL liquid(filler free so ) and I can't tkae above one serving or I get loose motions. If you don't take it without and acid your stomach just bloats and I get only 66mg of Magnesium.
AFAIR MgSO5 contains less Magnesium than MagCl, Do correct me if I am wrong.
So if the effect is the same isnt better to take MagT Orally.

MgSO4 is very cheap but how much can we asborb transdermally, maybe if anyone has the information please share it so we can do a cost analysis. WOuld soaking in a tub of MagSO4 be cheaper or just popping in a MagT pill.

 

 

 

Edited by Heisok, 15 November 2016 - 07:38 PM.

[pamojja]

 

I suffer and still have not overcome Mg deficiency. All what helps to avoid at least pain-full muscle cramps is to get a certain amount of elemental Magnesium, about 2 g/d. Tested all better bio-available forms, but none made a difference. After reading this post by niner 4 1/2 years ago I had the same experience with Mg oxide too.

 

Exogenous Mag-Oxide isn't a bad idea when you need it for your muscles - purchase some form of spray and apply directly to the skin.

 

If you need it for your muscles, then eating Mag isn't always the best solution - there are other ways to get it into the muscles.

 

You speak out of your own experience? Either regular muscle cramps and much too low RBC magnesium - and transtermal Maignesium improved that?

 

Like it did for me above a certain daily amount of elemental oral magnesium.
 

[Mind_Paralysis]

 

 

I suffer and still have not overcome Mg deficiency. All what helps to avoid at least pain-full muscle cramps is to get a certain amount of elemental Magnesium, about 2 g/d. Tested all better bio-available forms, but none made a difference. After reading this post by niner 4 1/2 years ago I had the same experience with Mg oxide too.

 

Exogenous Mag-Oxide isn't a bad idea when you need it for your muscles - purchase some form of spray and apply directly to the skin.

 

If you need it for your muscles, then eating Mag isn't always the best solution - there are other ways to get it into the muscles.

 

You speak out of your own experience? Either regular muscle cramps and much too low RBC magnesium - and transtermal Maignesium improved that?

 

Like it did for me above a certain daily amount of elemental oral magnesium.
 

 

 

Alas, I don't.

 

I just know that there are transdermal sprays containing Magnesium Chloride, which athletes and the like use - which apparently has a decent effect. I've never actually used it myself.

Magnesium Chloride isn't otherwise considered one of the more bioavailable forms, at least not orally. Apparently it works decently at least if you apply it directly to the area which needs supplementation.
 

Those that know more can feel free to correct me here.

[Heisok]

Not sure if a cramp is an indication of a deficiency localized in that specific part of the body. Could you show anything to support this?

 

As far as Magnesium Chloride, I also tried the "oil". There is no way to judge the dose which ones body is assimilating. I tried it on my legs, but it did not seem to absorb well. Simply produced a long stinging sensation. Instead, I used it regularly spread all over my chest and stomach. Twice a day. Once after showering, and then again before bedtime. It absorbed into my skin, and did not leave any stinging.  It did not add any benefits beyond the partial relief which I had already gotten from the Magnesium supplements which I tried before the Bisglycinate.

 

It may be that I have different cramping causes than those of the athletes which you mention.

 

 

 

 

I suffer and still have not overcome Mg deficiency. All what helps to avoid at least pain-full muscle cramps is to get a certain amount of elemental Magnesium, about 2 g/d. Tested all better bio-available forms, but none made a difference. After reading this post by niner 4 1/2 years ago I had the same experience with Mg oxide too.

 

Exogenous Mag-Oxide isn't a bad idea when you need it for your muscles - purchase some form of spray and apply directly to the skin.

 

If you need it for your muscles, then eating Mag isn't always the best solution - there are other ways to get it into the muscles.

 

You speak out of your own experience? Either regular muscle cramps and much too low RBC magnesium - and transtermal Maignesium improved that?

 

Like it did for me above a certain daily amount of elemental oral magnesium.
 

 

 

Alas, I don't.

 

I just know that there are transdermal sprays containing Magnesium Chloride, which athletes and the like use - which apparently has a decent effect. I've never actually used it myself.

Magnesium Chloride isn't otherwise considered one of the more bioavailable forms, at least not orally. Apparently it works decently at least if you apply it directly to the area which needs supplementation.
 

Those that know more can feel free to correct me here.

 

 

Edited by Heisok, 15 November 2016 - 11:40 PM.

[YOLF]

 

So I stopped taking Mg Threonate as it was imbalancing my Ca/Mg ratio and I waste too much Ca apparently. 

 

How does one notice that Ca/Mg balance is too far on the Mg side?

 

For me Ca citrate makes me spaced out. And I think I get enough Calcium from my diet anyway.

I take Magnesium threonate for brain health and not as a magnesium supplement.

 

 

Well, if I'm taking extra mg and my knees start to hurt, then I take more Ca, or I stop for a few days, then it's probably too much Mg. There are also a few things I take that increase Ca usage which make me more sensitive to the effects.

[YOLF]

 

A comment about Magnesium L-Threonate: It takes 2 gms or 3 capsules to get 144 mgs Magnesium. Generally the capsules are 667mg total per.The selling point for the Magnesium L-Threonate is that a higher percentage may cross into the brain. 

 

For cramping in my legs, I had limited success over the last 2 years using various quantities and types of Magnesium, in addition to other electrolytes. Nothing completely eliminated the nighttime cramps. I could not sleep on my back at all as the cramping would start. This included Epsom salts (Magnesium Sulfate) baths and long floats in Magnesium saturated isolation float tanks.

 

I am a little over 2 weeks into trying Magnesium Bisglycinate Chelate 3 times a day in addition to Magnesium from a multi nutrient vitamin style supplement which I have taken for years.

 

I have had no cramping at night, and I can sleep on my back.  I am keeping my fingers crossed that it continues. Large doses of DiMagnesium Malate, 1.5 gms per day of elemental Magnesium had partial improvement as did another Magnesium at 1.5 gms elemental Magnesium per day.

 

 

 

 

So intravenous MgSO4 performs equally well as oral MgT?

MAGNESIUM SULFATE will perform equally well as MAGNESIUM L-THREONATE taken PER ORALLY whether it is adminstered via IV or IM INJECTION, or TRANSDERMALLY (e.g. by soaking for 12+ minutes in a hot bath into which 1-2 cups EPSOM SALTS are dissolved)

With regards to how MAGNESIUM SULFATE taken PER ORALLY compares to MAGNESIUM L-THREONATE taken PER ORALLY, that would depend upon the respective BIOAVAILABILITIES; however, even if MAGNESIUM SULFATE were proven to be lower in BIOAVAILABILITY than MAGNESIUM L-THREONATE, it will still be considerably more economically to simply take whatever higher dosage of MAGNESIUM SULFATE yields equivalent absorption to the MAGNESIUM L-THREONATE

Therefore, MAGNESIUM SULFATE will in fact be the preferred choice over MAGNESIUM L-THREONATE whatever the administration method

 

 

Magnesium Sulfate in Oral form is laxative. What I believe the advantage in Taking MgT is that it does not give you a laxative effect so you can take a lot more orally. a pill of MagT gives around 144 mg of magnesium. That is not only much more than MgCl but it works out the same. I did not want to spend more money on MagT so I bough MagCL liquid(filler free so ) and I can't tkae above one serving or I get loose motions. If you don't take it without and acid your stomach just bloats and I get only 66mg of Magnesium.
AFAIR MgSO5 contains less Magnesium than MagCl, Do correct me if I am wrong.
So if the effect is the same isnt better to take MagT Orally.

MgSO4 is very cheap but how much can we asborb transdermally, maybe if anyone has the information please share it so we can do a cost analysis. WOuld soaking in a tub of MagSO4 be cheaper or just popping in a MagT pill.

 

 

 

 

I've been seeing progress with whole powdered foods (onion and banana... I don't mix them). Onion has lots of Sulfur which makes me feel great, and banana just seems to have a great complex of minerals in general... I can't find better for broad benefits. You could also eat bananas, but they go bad fast and you have to get them at a store.

 

My mineral stack as of late is as follows:

Morning:

Royal Jelly

10g dried banana

1-1.5g Ca diphosphate

2-4k iu of D3

Full dose of GCMSM

Generous amount of C-complexes with bioflavanoids

K/K2 complex

Just added CaThreonate

 

Night:

Royal Jelly

1g Ca diphosphate

.5g Ca Pyruvate (an AHA, so it helps with ECM)

200mg 20% Astragaloside IV ext (w/chitosan)

2k iu of D3

Full dose of GCMSM

Generous amount of C-complexes with bioflavanoids

Delta fraction tocotrienols

 

I tried a small amount of MgT w/ all this Ca, can't say one way or the other if it hurt or not, but not about to press the issue atm.

Generous amount of C-complexes with bioflavanoids

[YOLF]

Oh, and I was taking Mg aspartate and oxide in a well balanced chelated mineral complex.

[lumia]

Now, I want a definitive answer for this: Does Mg + T(eg from Ester-C) work the same as MgT? MgT remains the most expensive item in my stack, Mg + T is significantly cheaper, but FDA filings indicates Ester-C has about 3.3% T by weight of the vitamin C potency (Ester-C® comprises 76.60 mg/100 mg ascorbic acid, 9.18 mg/100 mg calcium, and 1.15 mg/100 mg threonic acid, and hydroxymethyl furanone occurs in an amount of 0.045 mg/100 mg; page 12 of http://www.fda.gov/u...t/ucm337465.pdf ), so 1,000mg Ester-C yields 33.3mg of T... While a daily dosage of MgT yields more than 1g.

Edited by lumia, 12 February 2017 - 09:17 PM.

[xatu01]

According to this research is magnesium-l-threonate actually rly different and more efficient at fear extinction ? Are other forms even avaible to do the same thing ? 

Check it :https://www.ncbi.nlm...pubmed/22016520

[Logic]

Magnesium is magnesium.  It's the L-Threonate IMHO:

L-threonate represses the glycoprotein dickkopf-1 (Dkk-1) via alkaline phosphatase activity; releasing ascorbic acid into the cell.
This enhances neurogenesis in the hippocampus, and stops papilla cells from dying and the hair-producing outer root sheath cells from stopping to work.

So perhaps we get the same amount of Magnesium from the L-Threonate form as any other, but its the vitamin C inside the cell, causing neurogenisis, that adds the extra brainy effect.

Dickkopf makes fountain of youth in the brain run dry:
 

Loss of Dickkopf-1 Restores Neurogenesis in Old Age and Counteracts Cognitive Decline:
 

Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage:
 

Neurogenesis and Alzheimer's disease: At the crossroads:
 

Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells:
 

Enhanced Production of Mineralized Nodules and Collagenous Proteins In Vitro by Calcium Ascorbate Supplemented With Vitamin C Metabolites:
 

Effects of L-threonate on bone resorption by osteoclasts in vitro:
 

http://www.longecity...osteoarthritis/

[startime]

Haha, OK!

Let me clarify what I recommend with regards to MAGNESIUM administration:

1) MAGNESIUM SULFATE adminstered via INJECTION; and/or

2) MAGNESIUM SULFATE administered TRANSERMALLY via soaking for 12+ minutes in a hot bath within which 1-2 cups ESPOM SALTS have been dissolved

If you are not willing or able to opt for either of the above; then I recommend the following alternative:

3) MAGNESIUM administered PER ORALLY; using any of the following three forms, all of which have good PER ORAL absorption: MALATE, GLYCINATE, or THREONATE (N.B. AVOID the OXIDE, CHLORIDE and CITRATE forms)

why to avoid the chloride ,which is among best to be absorbed and assimilated ?!

[nickdino]

What about "Magnesium Water"? It's magnesium-oxide dissolved in carbonated water which together makes magnesium bicarbonate. So it does solve in water, i wonder if anyone here knows how well it's absorbed by our bodies.