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Closing in on perfection

aniracetam pramiracetam piracetam

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#31 health_nutty

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Posted 21 March 2012 - 04:16 PM

I've actually stopped taking Piracetam (only racetam linked with irritibility for me). L-glutamic acid removed the irritbility but I never noticed any benefit (Note, that I tried in combination with Pram and Ani). I'm already taking 2 racetams I'm getting awesome results from.

#32 unregistered_user

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Posted 30 March 2012 - 11:00 PM

I'm assuming you're getting awesome results from Prami and Ani combined? I am taking Prami and my experience has left me questioning if racetams are really for me. After a month of continual Pramiracetam dosage I find that my verbal recall and speaking abilities seem to be stymied which is the opposite of what I was expecting it to do. I am taking it with 300mg Alpha GPC.

Perhaps Oxi is a better choice for me? Like you, I notice no benefit from piracetam other than sleepiness at higher dosages.

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#33 health_nutty

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Posted 31 March 2012 - 11:21 PM

I'm assuming you're getting awesome results from Prami and Ani combined? I am taking Prami and my experience has left me questioning if racetams are really for me. After a month of continual Pramiracetam dosage I find that my verbal recall and speaking abilities seem to be stymied which is the opposite of what I was expecting it to do. I am taking it with 300mg Alpha GPC.

Perhaps Oxi is a better choice for me? Like you, I notice no benefit from piracetam other than sleepiness at higher dosages.


Pram has the most immediately noticeable effects of increased motivation and self confidence. Aniracetam further improves my memory (but it is not something I notice right away). Piracetam makes me have weird side effects from irritability to anxiety. The irritability was improved by l-glutamic acid, but I would still get anxiety or feel burnt out mentally. Oxiracetam is a bit like Pram. It is also nice, but it takes more to have the same effect, thus making it less cost effective than Pram.

You are taking a very high dose of Pram. I would try dual-n-back with after varying doses of Pram (0mg, 100mg, 300mg, 500mg). Take the test 30 minutes after the dose. See if you notice any consistent results from the dose. This is a better test than how you "feel".

#34 parsons

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Posted 08 April 2012 - 11:22 PM

lithium orotate sounds pretty interesting. In this thread, the dosage for lithium orotate ranges from 1-120 mg. quite a spread. what's an effective but safe dosage to promote neurogenesis?

#35 health_nutty

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Posted 09 April 2012 - 05:37 AM

lithium orotate sounds pretty interesting. In this thread, the dosage for lithium orotate ranges from 1-120 mg. quite a spread. what's an effective but safe dosage to promote neurogenesis?


I too tried to find this out without any luck. I like my 5mg of elemental lithium dose every night (I think that is around 100mg of lithium orotate).

Edited by health_nutty, 09 April 2012 - 05:38 AM.


#36 health_nutty

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Posted 10 April 2012 - 03:17 AM

Methylene Blue: 250mcg split throughout the day
Benefits: NAD/NAD+ ratio, neurogenesis
Side effects for me: Slight increase in libido

ALCAR: 2 grams split into 2 doses
Benefits: increases aCh, neurogenesis
Side effects for me: slightly stimulating

Aniracetam: 1g split into 3 doses. Note: I lowered from 2g split 3x a day. At 2g, I was getting slight light headedness that would go away with more choline. However, it took a lot of choline and I ended up just lowering my dose.

Pramiracetam: 250mg in the morning and 250mg in the afternoon. (Lowered morning dose, 500mg seemed like I overdid it).
Side effects: Slight mania during the first few days.

125mg of l-glutamic acid once a day

1g of alpha gpc morning

Lithium: ~1mg at night from lithium orotate
Benefits: Mood, decreased anxiety, neurogenesis
Side effects: Sleepy and unmotivated the next day if I take more. (I lowered from 5mg to 1mg because ScienceGuy pointed out lithium can have anti-nootropic effects).

Bacopa: 500mg of Bacopin 20% extract at night
Benefits: Memory
Side effects: Initally sleepy and unmotivated the next day if I take 500mg or more.
Now my tolerance for Bacopa is increasing. I've upped this to 300mg during the day and 500mg at night.

Ashwagandha 7%: 500mg at night, 500mg split into 3 doses during the day.
Benefits: Stimulates NGF, reduces stress

Fish Oil: 2g morning and 2g again at night of concentrate yielding 3g of omega 3's
Benefits: Mood, neurogenesis, cardiovascular health
Side effects: None

Gingko Biloba 24/6: 250mg twice a day.
Benefits: Increased blood flow to the brain, supposed synergy with other noots.
Side effects: None

Phosphatidyl Serine: 100mg at night
Benefits: Neurogenesis, reduce cortisol, memory
Side effects: None
Notes: Initially I thought this was doing great things, but now it seems like it might have been placebo.

Other supplements:
Multi
Vitamin D 2000iu
vitamin K2 mk7 100mcg
Pom40p pomegranate extract

Notes:
Since starting Aniracetam, it seems like I can't get enough ACh precursors. Alpha-gpc or CDP-choline with ALCAR used to give me wicked ACh headaches. Now I can take either one (or both) with NO ACh headache. In fact, I had to lower the dose of Ani so I wouldn't get light headed from lack of ACh (taking more choline solved light headedness).

#37 karma02

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Posted 10 April 2012 - 03:46 AM

So what are the effects of this new stack. How do you feel ? What is your current job?

#38 health_nutty

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Posted 10 April 2012 - 03:59 AM

Background:
I'm a computer engineer, in my mid thirties, healthy overall. I've had some mild to moderate anxiety issues my whole life. Recently I've had some mild depression and motiviation issues.

Subjective and mood:
I feel more confident, my anxiety is almost non-existant, and my mood is much improved. These three areas improved dramatically.

Motivation and concentration
Pramiracetam has dramatically improved my motivation. Aniracetam helps with focus. Aniracetam also makes tasks that I don't want to do not so bad.

Memory:
Aniracetam probably had the biggest improvement on my memory (although Pram also helped). My memory was probably only slightly above average, and now I find it much easier to remember peoples names that I just met. Answers that I didn't even realized I knew come flying out without hesitation.

Problem solving:
Programming and visualizing complex processor scenerios has become easier. It is also easier for me explaining how things work to others (mentoring has become easier).

Since tweaking my stack I've noticed the following:
1) Even more stress reduction with the addition of Ashwagandha
2) Lowering Aniracetam dosage has eliminated the need for excessive choline precursors (although I find I still need a lot).

More is not better! :)

#39 SuperjackDid_

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Posted 10 April 2012 - 04:42 AM

I think you consume too much Noots ,i found Piracetam can cover them all effect ,problem is non-consistent or depend on some complex mechanism
Are you give Piracetam up ?
Why l-glutamic acid still there in stack if no Piracetam ?




Sorry for not well grammar ,please apologize if my question/statement feel rude ,i'm not native Eng speaker .

#40 SuperjackDid_

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Posted 10 April 2012 - 04:55 AM

Maybe try inositol instead of msg for irritability.


L-Theanine works pretty well for irritability too.



If Piracetam really deplete L-glutamic acid ,try these in quote supplement like just hide problem instead of solve it .

#41 karma02

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Posted 10 April 2012 - 12:08 PM

Interesting. I ordered Ani about 13 days ago from CH. It will be here today. I have a nice little assignment due tomorrow. Can't wait and see how that goes. I will use it in parallel with this :

http://www.learning-...e-subconscious/

and this:

http://www.learning-...arning-process/

Knowledge is power!

K02

#42 parsons

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Posted 10 April 2012 - 12:35 PM

lithium orotate sounds pretty interesting. In this thread, the dosage for lithium orotate ranges from 1-120 mg. quite a spread. what's an effective but safe dosage to promote neurogenesis?


I too tried to find this out without any luck. I like my 5mg of elemental lithium dose every night (I think that is around 100mg of lithium orotate).

you say 100mg above but your stack list says "Lithium: ~1mg at night from lithium orotate"

#43 health_nutty

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Posted 10 April 2012 - 03:27 PM

lithium orotate sounds pretty interesting. In this thread, the dosage for lithium orotate ranges from 1-120 mg. quite a spread. what's an effective but safe dosage to promote neurogenesis?


I too tried to find this out without any luck. I like my 5mg of elemental lithium dose every night (I think that is around 100mg of lithium orotate).

you say 100mg above but your stack list says "Lithium: ~1mg at night from lithium orotate"


Thanks, I should update the post. I wrote that when I was trying even lower doses. I just looked it up: I use this tiny scooper which holds 50mg of Lithium Orotate which is 5mg of elemental lithium.

#44 health_nutty

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Posted 17 April 2012 - 04:37 PM

Methylene Blue: 250mcg split throughout the day
Benefits: NAD/NAD+ ratio, neurogenesis
Side effects for me: Slight increase in libido

ALCAR: 2 grams split into 2 doses
Benefits: increases aCh, neurogenesis
Side effects for me: slightly stimulating

Aniracetam: 1g split into 3 doses. Note: I lowered from 2g split 3x a day. At 2g, I was getting slight light headedness that would go away with more choline. However, it took a lot of choline and I ended up just lowering my dose of Aniracetam

Pramiracetam: 250mg in the morning and 250mg in the afternoon. (Lowered morning dose, 500mg seemed like I overdid it).
Side effects: Slight mania during the first few days.

500mg of cdp-choline morning 250mg during lunch

Lithium: 5mg at night from lithium orotate
Benefits: Mood, decreased anxiety, neurogenesis
Side effects: Sleepy and unmotivated the next day if I take more.

Bacopa: 500mg of Bacopin 20% extract at night
Benefits: Memory
Side effects: Initally sleepy and unmotivated the next day if I take 500mg or more.
Now my tolerance for Bacopa is increasing. I've upped this to 300mg during the day and 500mg at night.

Ashwagandha 7%: 500mg at night, 500mg split into 3 doses during the day.
Benefits: Stimulates NGF, reduces stress

Fish Oil: 2g morning and 2g again at night of concentrate yielding 3g of omega 3's
Benefits: Mood, neurogenesis, cardiovascular health
Side effects: None

Gingko Biloba 24/6: 250mg three times a day.
Benefits: Increased blood flow to the brain, supposed synergy with other noots.
Side effects: None

Phosphatidyl Serine: 100mg at night
Benefits: Neurogenesis, reduce cortisol, memory
Side effects: None
Notes: Initially I thought this was doing great things, but now it seems like it might have been placebo.

Other supplements:
Multi
Vitamin D 2000iu
vitamin K2 mk7 100mcg
Pom40p pomegranate extract
Magnesium Malate

Notes:
Since starting Aniracetam, it seems like I can't get enough ACh precursors. Alpha-gpc or CDP-choline with ALCAR used to give me wicked ACh headaches. Now I can take either one (or both) with NO ACh headache. In fact, I had to lower the dose of Ani so I wouldn't get light headed from lack of ACh (taking more choline solved light headedness).

I've switched from Alpha GPC to CDP Choline. On paper Alpha gpc looks slightly better or at least the same, but I actually notice the effect of CDP choline and notice anything with Alpha GPC.
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#45 SuperjackDid_

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Posted 26 April 2012 - 06:41 AM

Hi health_nutty
Your stack now in perfect after did remove Piracetam out ?
What about L-Glutamic acid ,any update on your experiment for about irritability ,what you get rid Piracetam out ,if L-Glutamic acid solved irritability problem ?

A lot of member interest in Piracetam ,and you have been on it more than many year s ,why just give it up or you found something and not not need to tell us ? LOL

#46 health_nutty

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Posted 26 April 2012 - 05:45 PM

Hi health_nutty
Your stack now in perfect after did remove Piracetam out ?
What about L-Glutamic acid ,any update on your experiment for about irritability ,what you get rid Piracetam out ,if L-Glutamic acid solved irritability problem ?

A lot of member interest in Piracetam ,and you have been on it more than many year s ,why just give it up or you found something and not not need to tell us ? LOL


L-glutamic acid soved the irritibility issue, but Piracetam had other side effects such as causing anxiety or inability to concentrate. I could never pinpoint any positives from it (like I can do with Pram and Ani). At some point I just decided to give up on trying to make it work for me. I'm not holding out on you guys. My stack is all right here.

#47 SuperjackDid_

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Posted 27 April 2012 - 04:58 AM

You should start from micro dose 1mg effective to me ,without side effect .

#48 health_nutty

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Posted 27 April 2012 - 04:25 PM

You should start from micro dose 1mg effective to me ,without side effect .


1mg? Can you actually notice anything with 1mg???

#49 dsohei

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Posted 05 May 2012 - 10:24 PM

love your log HN, a question: does your stack help you mostly with analytical comprehension, creative behavior, motivation, etc?
i dont want to sterotype you but sometimes i feel when people are over the moon about certain substances it's because it enhances their natural tendencies...

#50 health_nutty

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Posted 07 May 2012 - 05:01 PM

love your log HN, a question: does your stack help you mostly with analytical comprehension, creative behavior, motivation, etc?


Motiviation and confidence.

i dont want to sterotype you but sometimes i feel when people are over the moon about certain substances it's because it enhances their natural tendencies...


The areas my stack helped most are areas I was weak at before: motivation and confidence.

#51 health_nutty

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Posted 08 May 2012 - 05:34 PM

I'm experimenting with CILEPT right now: Forskolin and Luteolin.

I'm still trying to find the appropriate dosage.

Currently I'm taking 200mg of 10% Forskolin with 100mg of Luteolin (split into 4 doses).

500mg of 10% was too much and was making me light headed.

Edited by health_nutty, 08 May 2012 - 05:34 PM.


#52 karma02

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Posted 09 May 2012 - 11:10 PM

I don't know why, but your nickname makes me think of a healthy nutt on a wednesday.

p.s. I know I am not adding anything pertinent to this topic, however, I did take 40 grams of piracetam in one day the other day if anyone is interested ?

Edited by karma02, 09 May 2012 - 11:11 PM.


#53 Sartac

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Posted 12 May 2012 - 03:55 AM

Nice log, HN. These reviews are a big help, since I'm looking for very similar results with mitigating anxiety and increasing confidence.

Will be interested to read further on your forskolin and PS determinations. Also, what are your thoughts on lactoferrin and/or melatonin supplementation, if these have been of interest?

#54 health_nutty

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Posted 12 May 2012 - 05:36 AM

Nice log, HN. These reviews are a big help, since I'm looking for very similar results with mitigating anxiety and increasing confidence.

Will be interested to read further on your forskolin and PS determinations. Also, what are your thoughts on lactoferrin and/or melatonin supplementation, if these have been of interest?


I'm going to pause my Aniracetam supplemention until I straighten out my forskolin / luteolin combo. I think it has promise, it is just easy to overdo it.

I take low dose (1mg) melatonin for a sleep aid as needed. I done any research on lactoferrin.

#55 medievil

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Posted 12 May 2012 - 06:38 AM

How does methylene blue synergize with aniracetam and pramiracetam? When i add more stuff our stacks would like fairly simular so im curious for your results.

Edited by medievil, 12 May 2012 - 06:39 AM.


#56 medievil

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Posted 12 May 2012 - 06:44 AM

Im taking
Lexapro

nac
A
niracetam
Cod liver oil
Glutami
ne
Stimulant

Im gonna replace nac with either curcumin or resveratrol and my next additions will likely be methylene blue; pramiracetam and alcar; like in your case ani works for focus but i still have trouble with motivation so im looking forward to the addition of prami. Im also interested in mirtazepine for sleep. I also want to replace glutamine with l glutamic acid and cod liver oil with fish oil for higher levels of omega3.

Edited by medievil, 12 May 2012 - 06:45 AM.


#57 health_nutty

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Posted 13 May 2012 - 07:38 PM

How does methylene blue synergize with aniracetam and pramiracetam? When i add more stuff our stacks would like fairly simular so im curious for your results.


It synergizes well because it has a seperate mechanism of action. Let me know what you think.

#58 medievil

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Posted 19 May 2012 - 12:39 AM

I replaced nac with ginseng wich is a 5HT2A agonist like aniracetam; i ran out of glutamine wich im looking to replace with l glutamic acid; id also like to add l glutamic acid; choline bitartrate and pramiracetam up next. Also replacing lexapro with sertraline as lex wasnt very effective for premature ejaculation.

#59 unbeatableking

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Posted 21 August 2012 - 01:00 PM

Hey health_nutty, how is the serine treating you? :D

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#60 choqueiro

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Posted 21 August 2012 - 05:23 PM

Hey health_nutty??

What brand of Aniracetam do you use??





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