2 votes
Posted 26 January 2014 - 10:52 PM
Posted 27 January 2014 - 12:36 AM
My supplier indicated that 7,8-d will be ready by late Feb. If anyone wants a free sample I can offer like 10 @ 1g.
Posted 19 May 2014 - 03:00 AM
So did anyone try this stuff? did it work? What happened to the group buy?
Group buy doesn't seem to be necessary, it's available here:
http://tht.co/7.8-Di...oxyflavone.html
Currently waiting for delivery (hopefully soon).
I think it only recently became available so I think everyone else is waiting too.
Posted 20 May 2014 - 01:35 AM
So did anyone try this stuff? did it work? What happened to the group buy?
Group buy doesn't seem to be necessary, it's available here:
http://tht.co/7.8-Di...oxyflavone.html
Currently waiting for delivery (hopefully soon).
I think it only recently became available so I think everyone else is waiting too.
Ahh thanks! But isn't any company doing trials for this stuff for treatment of depression or anything? I mean it seems pretty promising but I could not find anything?
Posted 20 May 2014 - 05:20 PM
Just ordered myself some. Strange though as website said $21.99 cost. When I went to pay for it on Paypal it displayed a cost of $29.99+P&P! Bit dodgy is it not? Anyone vouch for this retailer and the purity and quality of the substance? I bought it anyway as its still a decent price for a months supply
Posted 22 May 2014 - 04:30 PM
Hmm, just ran across this, and it may already have been answered:
"A similar compound, 5,7-dihydroxyflavone, has been approved for bodybuilding use in humans."
NOTHING has been "Approved" for bodybuilding use. Have you ever gone to the Doc and said, "I need an approved bodybuilding drug"?
What am I missing here?
Posted 23 November 2014 - 12:35 PM
This report from Reddit seems in agreement with the title "Cure depression in 3-4 days" of this thread.
Let me start by stating that I took a huge risk with this compound. unverified vendor, unverified product with no COA, and pre-existing conditions possibly complicating the testing process. I wouldn't recommend anyone do something like this with a 'fuck it, lets do it anyway' attitude, and I got extremely lucky that things didn't go horribly wrong.
It started on Longecity, sifting through new and interesting RC's, trying to find something that would make a discernible difference in my quality of life without undesirable side effects. 7,8-DHF, emoxypine, and tianeptine were all on my radar. I did my research on all three, and decided to go with 7,8-DHF first, and I would deal with the other two if/when 7,8-DHF didn't live up to its hype.
I ordered 7,8-DHF from tht.co for a total of 36$, and it was here in 2 days which was unexpected, but convenient and awesome nonetheless. when it got here, I checked out the packaging and snapped a few pics. Let me just say that I've never seen a vendor that has this much put into their packaging. Its a black plastic box with Trans-human Technologies name and logo on it, with an RC warning;not for consumption on it. I open it up and find a black, barely light-permeable glass container, approximately 1.5" x 2", labeled 7,8-Dihydroxyflavone, with the CAS#, and THT logo. It comes with a black double sided 3mg;30mg spoon. It had a 'safety seal' on the top after you unscrew the lid. Total weight on the powder on arrival was 977mg(±2mg). I wasn't really too happy it was short, but it was only missing one dose and the company is still in its infancy, so I didn't dwell on it. The powder is bright yellow, crystalline, with a mild mustard-like smell and not much of a taste. i looked at it under a 100x electronic microscope for shits and giggles, and found the consistency was very... consistent. There was no noticeable 'cut' or solid contaminants in the powder whatsoever.Here are the pictures of the packaging.
My medical history consists of treatment resistant depression/dysthymia, anxiety, and a recent Temporal-Lobe Epilepsy diagnosis. i have HPPD-like symptoms brought on by excitotoxicity and excessive seizures a few months back also. I've been out of work all year because of seriously debilitating insomnia and cognitive problems, also brought on by seizures. Before I started testing, I slowed down on my anti-convulsant supplements enough to keep me stable without interfering with my results, and stopped taking coluracetam a few days before.
DAY ONE: Now, on to testing. I started with sublingual, because there's talk of a roughly 1% bio-availability orally. Dosing was 2, 4, 8, then 16mg. 2mg did nothing as expected. When I added 4mg 30 minutes later, I felt a slight change in perception, and I interpreted it as depersonalization which made me second guess the powders validity instantly. I was going at this blind, and I was expecting a few surprises. I added 8mg 30 minutes later for a total of 14mg, and about 20 minutes in I had a butterfly/happy feeling comparable to a small L-Tyrosine dose with a bit of thought de-cluttering, on top of an even further and more apparent altered perception. Added 16mg an hour later for a total of 30mg, and the effects seemed to peak there. I had crystal-clear thought, with a mood and energy boost. 30mg is the recommended dose, so i wasn't trying to over-do it the first day with it. Anyway, this lasted for around 4 hours before i slowly drifted back into a low energy, unmotivated, depressed state. It was a great experience, but it didn't last long.
DAY TWO: I was hoping sublingual administration would give me the same effects today, but I was wrong. 30mg under the tongue for 40 minutes, and I felt nothing. So I started my second round of testing after a few hours of 'washout'. I don't recommend
this methodthe following method of administration, but I read a Longecity thread of a guy who had no luck with sublingual administration, so he started the recommended dose but was insufflating it instead. Just as a note, I had been taking my coluracetam insufflated for a few weeks, and cut my dosing from 60mg orally;25mg sublingual, to 3-5mg insufflated with even stronger results than the other two methods. Either way, I was determined to see those results again, especially because I had spent the last of my money on this stuff. I started with 4mg insufflated, with unremarkable results. Added 10mg, and I started feeling that mood elevation I felt the previous day, with an unremarkable change of perception. Added 15mg more, and I had peaked again. clear head, great mood, and an unusual amount of motivation to get shit done. Because I stopped at 30mg the day before, I want to see how far I could take this awesome feeling, so I bumped 10mg more an hour and a half later. This resulted in a wave-like dizziness for a solid 30 minutes until is leveled out into an unfamiliar but consistent perception of reality that was very apparent. Two hours after adding the unnecessary 15mg, I was back to my 'peak'. Needless to say, I over-did it on day 2. HPPD-like symptoms, especially the visual ones, are gone. I feel like the 'altered perception' is actually a more clear reality, but it has been so long since i felt 'normal' I'm not sure. I like it though, because its consistent and makes me feel less like I'm completely nuts.DAY THREE: I insufflated 30mg to start, with a slightly more dampened effect than day two. Apparently I didn't learn anything from day two, because I stepped up dosing by 10mg once, and then 20mg three times, all with an hour in-between. Between 40mg and 100mg insufflated, I notice no positive change at all. The only thing that changed was a slight irritability after the 60mg mark. This is when i really started to doubt what i had was real 7,8-DHF, and just forgot about it for the rest of the day, while in a slight rage. That night I started researching other compounds that could possibly be in that glass container, that at the time i was unsure about. I came across Chrysin, which shares chemical and physical properties identical to 7,8-DHF. That idea lasted until I realized I would be sweating testosterone, and Chrysin couldn't have possibly given me the effects I felt. I was done trying to figure it out at that point, so I did a few dabs to chill out and relax for the remainder of my night. I fell asleep a little bit earlier than i usually do, but I can't pin that on any one thing. It was a weird day, so who knows.
DAY FOUR 30mg insufflated, and it was like day two effects all over again. Great mood that lasted about 6 hours, and motivated like a motherfucker. At this point, I noticed the depression and anxiety that has haunted and tortured me for the last 5 years is COMPLETELY GONE. I was sociable, happy, and zero suicidal thoughts. suicidal thoughts were a daily thing for me normally, and going a day without finding comfort in picturing a 9mm hollow-point from the next room over, going through my brain, was something I never thought would feel so damn good. This was the point where i didn't give a diddly-FUCK what was in that glass container. Whatever it is, it works. Its giving me a knot in my stomach writing this, and just thinking about how amazing it feels to have those thoughts disappear. I still have trouble comprehending how fast this stuff did what it did. 5 years of depression < four days of still-questionable wonder drug. I fell asleep 4-5 hours earlier than normal that night.
DAY FIVE woke up at 5:30am, set up a 30mg rail with a genuine smile on my face, and went to work for the first time all year. Other than the heat, I actually had fun busting my ass building houses. I was talking to my buddy I hadn't seen in over 6 months, made a new friend, and did the best I could to watch what I was doing. Doing construction requires the ability to know where everyone is, what is where, and safety is always at the top of the "shit-to-do" list. I have never had a day a easy-peasy as this one. Somehow, I picked up right back where I left off in January as a greenhorn, learning all there is to know about construction and safety. My cognition was spot on, and I ended up needing less assistance than I normally would. All around just a great day, while starting to work out my financial issues at the same time.
DAY SIX/SEVEN More work! Things are going amazing. Money is coming in, paying off debt, and moving forward with my life. Insomnia has been completely corrected at this point. Yeeaaaah, no more sleepless nights!
DAY EIGHT Still having consistent results, and its now Saturday. Knowing how susceptible I am to rebound, I cycle off today to get a feel for how bad it could be. It started like any other day i had taken 7,8-DHF, but the effects weren't sustained throughout the day. Around 3pm I was slightly irritable, but that only lasted for an hour or two. It was right back to happy, but slightly less motivated than when i was on 7,8-DHF. It seemed I was on a slight down-slope as far as effects go. visual HPPD-like symptoms were starting to reappear.
DAY NINE Its sunday, and i decide to give the off-cycle two days instead of one, just to make sure. I noticed no drastic change, and the down-slope drifting has slowed down and almost stopped. I feel normal again today, but more happy with a better outlook on life. I noticed the HPPD symptoms were back and very noticeable, but reality seemed to be intact still. I'm still very far from depressed, although I do feel slightly anxious with a bit of akathisia, but still much less than usual. This was the end of my first off-cycle, because I had work the next day and needed to make sure things would stay like they were. I wasn't about to screw it up after how much progress I have made.
DAY TEN/ELEVEN 30mg insufflated in the morning, and everything is back to optimal for me. No new effects, just more content with how I was doing, and I noticed I've been thinking about going out a lot lately, which I never do. I got back in contact with a few lost friends, and made plans. Things are good.
OVERALL CONSENSUS/FINAL THOUGHTS I've had an amazing experience with this stuff. Cognition is smooth and improved, learning is at least 2x faster, and my mood is stable and elevated. How much of this is placebo, I'm not sure. It muted my depression, anxiety, and to ice this awesome-cake, i haven't needed anti-convulsant supplements in about a week. I've had very minimal stress, which led to much less myoclonic jerking and zero auras or seizures. It was after day one when i was off of everything completely, and I normally have instant rebound with NMDA antagonists which usually causes auras or seizures, but somehow, there was no rebound at all. I've felt great since being off of them, only because I don't have to worry about taking my meds 3x/day. I'm just not sure how long i will be able to take 7,8-DHF, because I'm slightly concerned about TKrB downregulation.
overall, 10/10 for efficacy and speed. The only modification i made to the insufflation method was changing the consistency of the powder. The large-ish crystals don't work very well for insufflation, and there were a few small clumps, so I mashed the shit down to a flour-like consistency. It worked like a charm!I've been putting this post off for a few days because I've been so busy, and the only reason I had time to write this out is because this morning the power kicked out for a minute and it reset my alarms before they went off, so I missed work but its pouring anyway. My boss is just happy I'm back, and so am I. :D
UPDATE
DAY 17/18 the last two days I've been starting to notice diminished effects. Im not sleeping as well, my motivation is starting to fade, and things seem to be going back to normal. anxiety is still nowhere to be found, but the depression is starting to creep back into my thoughts. so, at least one good change stuck around. also, the HPPD symptoms have been drastically reduced and it seem to be stable where it is. 30mg, and even 40mg just doesnt seem to be enough anymore, and I suspect tkrb downregualtion. I wont let it go any further. My testing with 7,-8DHF comes to an end today, for a total of 18 days out of my hopeful 28 day experiment. I will pick back up on 7,8-DHF when the more potent analoge 4,DMA-7,8-DHF is available. It was one of my more effective and enjoyable experiments, mostly because of the positive response and lack of side effects. Now its on to the next one!
In the rest of the thread, he is still possitive (not elaborating much though) but he got issues from insufflating 7,8-Dihydroxyflavone.
This shit stays in the lower part of my nose for a solid 24 hours, maybe more if I didn't clean it out. Plus, since i haven't been rotating sides, I've been having pressure issues in my right ear and it randomly pours fluid down my throat at night on days I don't cycle off. There's a canal from your nose to your ear that is apparently known to get swollen and irritated when you put shit up there. I'm no doctor, and I'm not even sure of the name of the canal, so it really depends on the user. Infection and shit is 'out there' but crazier shit has happened.
The reason he uses insufflation as ROA, is a much better bioavailability (according to his experience) than sublingual, he seems to believe that sublingual is far inferior and he does not have the money to spend on larger doses.
Posted 08 November 2015 - 12:34 AM
I'm into Day 2 of trying to recreate the experience of that guy on reddit. Nothing to report so far. No immediate effects from snorting 30 mg on either Day 1 or Day 2. I think I can feel some of it slipping down my mouth, although I'm not 100% sure. Tried the sublingual route first, but it just didn't seem to dissolve. Instead appeared to stick to my teeth and gums.
The reddit post makes reference to a post/thread on Longecity (see DAY TWO entry). Can anyone find the relevant thread?
Posted 08 November 2015 - 09:31 PM
I'm into Day 2 of trying to recreate the experience of that guy on reddit. Nothing to report so far. No immediate effects from snorting 30 mg on either Day 1 or Day 2. I think I can feel some of it slipping down my mouth, although I'm not 100% sure. Tried the sublingual route first, but it just didn't seem to dissolve. Instead appeared to stick to my teeth and gums.
The reddit post makes reference to a post/thread on Longecity (see DAY TWO entry). Can anyone find the relevant thread?
I hope you ll have some good results! I am a little sceptical for this as its available for a while now, and there is no much interest...
Please give some feedback, my mood is a little low this days and I am interested to try anything new with potential.
Posted 22 November 2015 - 01:46 AM
Today I had one my first experiences with Salvia.
I will be telling the experience soon and hope to get opinions about the following:
The KAPPA OPIOID SYSTEM, how it affects behavior and whether up or down-regulated state is more beneficial more a 21st century smart human.
First of all this is the first hallucinogen I have had an experience with and was not sure what to expect in general. I thought I would get something like virtual reality and I will be in the observer's point of view. What happened was quite fascinating, though.
The first time I did it was weird, it took me by surprise and I got into a dream like state where I could still think.
The third time I did salvia, after a few minutes of the dream like state I was back in the reality. I soon realized however, that my state of consciousness is alter. I felt like I am PURE CONSCIOUSNESS, other people have called this "death of ego". The feeling of SELF was not the entire body and mind but the PURE CONSCIOUSNESS only.
Imagine you have a large human like robot, of a size of a large building, and you are sitting somewhere in the head of the robot. Visualize your world of at this point. How would you see the world ? What would you feel ? This is what I was feeling during the experience. The robot was my BODY and the driver was MY CONSCIOUSNESS sitting in my head, observing the world.
A lot of my subconscious processes, that work PARALLEL to the consciousness to produce behavior were barely present. Anxiety, fear, shame was basically nonexistence. There was only PURE CONSCIOUSNESS. I could do and say precisely ANYTHING I wanted to do. Have you experience social anxiety or discomfort in social situations, when it feels you don't have control ? When it feels your voice, your face expression or your behavior is partially out of your CONSCIOUS control, being governed my circuitry of fear, anxiety, social acceptance, anger or anything else ?
Salvia was the EXACT OPOSIT of that. All those were inexistent. Every part of the behavior was under complete control.
My BRAIN FOG and DEPRESSION was gone. My thought was CLEAR and CLEAN.
Now here is my hypothesis of the neuropsychiatry that was happening:
Salvia has a very clean action - KAPPA OPIOID AGONIST.
Kappa opioids and Mu opioids have somewhat opposite effects. Kappa Agonist are supposed to have no euphoria whatsoever.
One of recent Depression models is that it's a state of UPREGULATED KAPPA OPIOID SYSTEM.
Kappa Opioid System is hypothesized to represent the APPROACH / AVOID spectrum of the person towards challenges.
I read about the above and decided to give Salvia a try. I wanted to AGONIZE the receptors to achieve LONG term DOWNREGULATION of the system. I was expecting to feel fear and dysphasia after few minutes of administration, but was stunned to achieve the full control and pure consciousness I was talking about.
One explanation is the following. Kappa neurons are usually coupled with dopamine neurons. Dopamine in the anxiety and fear systems creates anxiety and fear. Kappa neurons have inhibitory action on dopamine neurons. Increased Kappa activity caused my Salvia my decrease the activity of the subconscious areas of the mind, leaving a feeling of PURE CONSCIOUSNESS.
Here is the DILEMMA, however !
Why is it then that previously, DOWNREGULATED KAPPA SYSTEM was considered preferable ? This is inconsistent with what I observed.
Some people have experimented with JDTic which is a KAPPA ANTAGONIST. I would love to hear how they felt for the acute and withdrawal states. Any parallels ?
Anyone else has similar experiences with Salvia ?
P.S. I previously associated DOPAMINE with increased CONSCIOUS control. However being high on Salvia, I snorted some RITALIN which had NO EFFECT on the drive, motivation or thought process of my PURE CONSCIOUSNESS.
Posted 07 December 2015 - 08:35 AM
All you guys have to do is request the product you seek from reliable sources like Swanson Vitamins and or Powdercity. I only know of 1 company who has the product you all speak of which I had been curious about as well:
http://www.primordia..._7c799932980305
It's 20 mg a pill, the bottle has 60 pills and it goes for $25. It is expensive. But does anyone here have experience with it?
Posted 13 June 2016 - 11:09 AM
I'm not sure why you guys talking about these depressing high prices for 7,8dhf when I was able to buy it for about $25 here:
http://www.antaeusla...oxyflavone.html
20 mg per capsule, 60 capsules. Suggested dose was to take 2 capsules daily. I started off with 1 just to test the waters. I followed the directions to stack it with Queen Bee Acid:
http://www.antaeusla...n Bee Acid.html
It was also suggested to stack it with omega-3 acid which I have the Lovaza (prescription omega-3). I feel great within 2 days even at low dose of the stack, but I upped my dose to the 2 capsule suggestion. I do not feel depressed at all. I feel like jumping around actually, all in joy. I feel like I'm hallucinating on shrooms without the visuals of course, more like mental hallucinations (aka day dreaming and happy). My sleep is good, I hear God talk to me in my sleep (like I'm a happy Schizo considering 7,8dhf crosses the blood brain barrier).
For the record, I got off my prescription amphetamine Dexedrine 2 weeks before trying this stack. I'm off Dexedrine 3 weeks now and I do not even miss the dopamine it gave me (nor the euphoria). In other words I can handle life without Dexedrine.
My girlfriend thought I felt heavier (I didn't gain weight) so I don't know what 7,8dhf does for the muscles or physique but she felt I was heavy. I think my head feels "fuller" so in other words these products seem to be legitimate. The only company I could find selling both those products.
Posted 13 March 2018 - 12:19 PM
Have you guys considered something to upregulate trkb receptor expression in order to prevent downregulation from 7,8-DHF use? On the top of my mind, Memantine increases BDNF/GDNF expression in several brain areas and also promotes trkb induction. Maybe something like that can help with 7,8-DHF tolerance.
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