4 replies to this topic

[Logic]

The Anthelmintic Drug Mebendazole Induces Mitotic Arrest and Apoptosis by Depolymerizing Tubulin in Non-Small Cell Lung Cancer Cells, Ji-ichiro Sasaki,Rajagopal Ramesh,Sunil Chada,Yoshihito Gomyo,Jack A. Roth andTapas Mukhopadhyay, Molecular Cancer Therapy November 2002 1; 1201

Mebendazole Elicits a Potent Antitumor Effect on Human Cancer Cell Lines Both in Vitro and in Vivo, Tapas Mukhopadhyay,Ji-ichiro Sasaki,Rajagopal Ramesh, and Jack A. Roth, Clinical Cancer Research September 2002 8; 2963

Mebendazole Induces Apoptosis via Bcl-2 Inactivation in Chemoresistant Melanoma Cells, Nicole Doudican, Adrianna Rodriguez, Iman Osman and Seth J. Orlow, Molecular Cancer Research, August 2008 6; 1308

Mebendazole inhibits growth of human adrenocortical carcinoma cell lines implanted in nude mice, Daniele Martarelli, Pierluigi Pompei, Caterina Baldi and Giovanni Mazzoni, Cancer Chemotherapy and Pharmacology, Volume 61, Number 5, 809-817

Mebendazole Monotherapy and Long-Term Disease Control in Metastatic Adrenocortical Carcinoma, Irina Y. Dobrosotskaya, MD, PhD, Gary D. Hammer, MD, David E. Schteingart, MD, Katherine E. Maturen, MD, Francis P. Worden, MD, Endocrine Practice, Volume 17, Number 3 / May-June 2011

Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme, Ren-Yuan Bai, Verena Staedtke, Colette M. Aprhys, Gary L. Gallia and Gregory J. Riggins, Neuro Oncology, (2011) 13(9): 974-982


NB: Teva Pharmaceuticals, announced on October 7, 2011, that they have ceased manufacture of this product. As of December, 2011, it is no longer available from any manufacturer in the USA. No reason was given for this discontinuation...

[CaptainFuture]

Thanks for posting this. I don't understand why they stopped producing it in the USA.

[MrHappy]

Probably ahead of their new chemotherapy product?

[CaptainFuture]

Which costs 100 times more and has roughly the same probabilities of outcome.

[Logic]

Links for the first post:

The Anthelmintic Drug Mebendazole Induces Mitotic Arrest and Apoptosis by Depolymerizing Tubulin in Non-Small Cell Lung Cancer Cells, Ji-ichiro Sasaki,Rajagopal Ramesh,Sunil Chada,Yoshihito Gomyo,Jack A. Roth andTapas Mukhopadhyay, Molecular Cancer Therapy November 2002 1; 1201

http://www.ncbi.nlm....0Cancer%20Cells


Mebendazole Elicits a Potent Antitumor Effect on Human Cancer Cell Lines Both in Vitro and in Vivo, Tapas Mukhopadhyay,Ji-ichiro Sasaki,Rajagopal Ramesh, and Jack A. Roth, Clinical Cancer Research September 2002 8; 2963

http://www.ncbi.nlm....and%20in%20Vivo


Mebendazole Induces Apoptosis via Bcl-2 Inactivation in Chemoresistant Melanoma Cells, Nicole Doudican, Adrianna Rodriguez, Iman Osman and Seth J. Orlow, Molecular Cancer Research, August 2008 6; 1308

http://www.ncbi.nlm....elanoma%20Cells


Mebendazole inhibits growth of human adrenocortical carcinoma cell lines implanted in nude mice, Daniele Martarelli, Pierluigi Pompei, Caterina Baldi and Giovanni Mazzoni, Cancer Chemotherapy and Pharmacology, Volume 61, Number 5, 809-817

http://www.ncbi.nlm....n%20nude%20mice


Mebendazole Monotherapy and Long-Term Disease Control in Metastatic Adrenocortical Carcinoma, Irina Y. Dobrosotskaya, MD, PhD, Gary D. Hammer, MD, David E. Schteingart, MD, Katherine E. Maturen, MD, Francis P. Worden, MD, Endocrine Practice, Volume 17, Number 3 / May-June 2011

http://www.ncbi.nlm....cal%20Carcinoma

Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme, Ren-Yuan Bai, Verena Staedtke, Colette M. Aprhys, Gary L. Gallia and Gregory J. Riggins, Neuro Oncology, (2011) 13(9): 974-982

http://www.ncbi.nlm....ma%20multiforme

The reason for doing these links is that I feel this info is very important! (Unless I'm being an idiot, which is altogether possible )

At the risk of being figurativly tarred, feathered and tossed out the forums; there seems to be a link between parasites and cancer!?
See some of the links here:

http://www.ncbi.nlm.nih.gov/pubmed

But more on that later...