Tweedlover indeed there are other papers indicating life extension with fullerenes:
Another angle - I am not a scientist, but this 2008 study appears to show a lifespan increase of 11% and increased brain function from dosage of some kind of Fullerene SOD Mimetic... http://www.owndoc.co...pan-of-mice.pdf
- Indeed, this paper from researchers in the US [1]. Here are the lifespan curves, you can see it was done in a lot more mice ("a" is a part of "b")
C3-qurvival.png 84.03KB
41 downloadsand just below in the paper you can see that weight and food consumption suggest it is not crypto-CR (true to for the C60oo study).
- The C60oo authors told me about another paper with
other fullerenes from authors in China showing mild life extension in rodents. I'm not able to find it now (
perhaps someone else here?[2]). They told me they attribute the much greater longevity of C60oo due to the fully optimized structure of C60 to capture free radicals thanks to the numerous double bounds on the buckball structure. But it is just a hypothesis of course.
- While searching for [2] I found another paper [3] from reseachers in the US showing life extension if various species with other fullerenes.
To me this is all nice but the claims/results of the C60oo study are particularly extreme. Therefore what I am doing.
* * *
[1] Kevin L. Quick, Sameh S. Ali, Robert Arch, Chengjie Xiong, David Wozniak, Laura L. Dugan. A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice. Neurobiology of Aging 29 (2008) 117–128. Free full text:
http://www.owndoc.co...pan-of-mice.pdf[2] ?
[3] Gao J, Wang Y, Folta KM, Krishna V, Bai W, Indeglia P, Georgieva A, Nakamura H, Koopman B, Moudgil B.
Gao J, Wang Y, Folta KM, Krishna V, Bai W, Indeglia P, Georgieva A, Nakamura H, Koopman B, Moudgil B.
PLoS One. 2011;6(5):e19976. Free full text http://www.ncbi.nlm....25/?tool=pubmed
Edited by AgeVivo, 05 June 2012 - 05:28 AM.