6 replies to this topic

[Imagination]

I noticed some people include CoQ10 in there stacks, does anyone use this for nootropic purposes? What benifits does it give specifically to the brain? and is it worth adding?

I've tried searching but all I come up with is threads with it included in peoples stacks and can't find any sort of explaination on why its there.

Cheers

[jupiter3888]

I take it if I'm feeling burnt out from intense physical activity every day of the week.

Last year I was doing 2 hrs hard martial arts training at least 5 days a week and I was starting to feel completely physically exhausted no matter how much sleep I got or how many nutrients/calories I had. I started taking 2x50mg doses each day and within a few days I felt a lot better.

Apparently CoQ10 is VERY beneficial for a healthy strong heart and energy production but lots of exercise can cause the levels of coq10 to drop.

Anecdotally, after a few weeks of this I felt that my heart could handle anything I threw at it, disregarding the other parts of my body!

p.s. my bottle of coq10 warns not to use it with warfarin therapy.

[mystilleef]

As far as I've researched cellular rejuvenation, cellular energy production and anti-oxidation properties are its main strength. I take it and its cousin Idebenone once a day. I believe it is possible for Idebenone to cross the brain blood barrier, where it serves as an anti-oxidant. Basically it keeps you young, healthy and energetic at the cellular level.

[khemix]

CoQ10 is a substance that promotes energy production in cells, including those in the brain. Your body synthesizes its own CoQ10 but additional amounts can be obtained from diet and supplementation. The problem with the supplement form is that it does not cross the blood-brain-barrier unless it is specially coated and so it doesn't reach the brain cells and is therefore not a nootropic. The Vitaline brand (ie. http://store.drhyman.com/Store/Show/Optimizing-Your-Health/674/CoQ10-%28Vitaline%29-100mg,Tropical-Fruit) is one example of a coated version which does cross the BBB and therefore exerts nootropic effects. Another option is Idebenone, a synthetic analog which is more potent, with BBB crossing properties.

So yes, if it can reach your brain it functions as a nootropic because it gives more mental stamina and functions as an antioxidant.

Edited by khemix, 16 July 2012 - 06:07 AM.

[ninjavendetta]

Never talen CoQ10 as a nootropic but:
I took pure CoQ10 a few years ago to boost endurance.
Within about 3 weeks i went from walking at a normal pace for several blocks to running the same distance with no problems. My cardio has been something that has always let me down.
As a martial artist it really helped with my cardio endurance immensely. going from being worn out from a warm up to wanting to do ALOT more training at the end of every class.

[FutureOrtho]

Any input on the ideal dosage for optimal results?....I picked some up recently, only 30mg/ dose. I read a study where there is a good synergistic relationship between piracetam, ALCAR, and CoQ10 which is the main reason for picking it up. But the benefits on it's own seem compelling.

[mia22]

I have a nice bottle of ubiquinol shelved at the moment.
There was a thread a little while back where studies were posted showing accumulation of something or other in the hearts of mice correlated with coq10 supplementation followed by further debbie downers(not living up to the hype).
Seems quite contradictory to the other claims, which were also why I purchased a bottle, as well as the anecdotal accounts given here.
Clarification would be nice, and they were mice and not humans after all...
I hate when that happens with supplements as I don't know enough to discern the wheat from the chaff.

Edited by mia22, 25 July 2012 - 01:03 AM.