3 votes
Posted 28 May 2016 - 11:02 AM
Thank you, the reports were a little hard for me to understand but I got the gist of it that it helps inflammation. They keep mentioning water soluble C60 so I hope it doesn't make a difference. Just to be able to type again using that finger is amazing.
Here is a better thread to post your positive results, as this one is about potential toxicities--
C60 Surprises - Anecdotes Of Unique Health Benefits
Edited by Turnbuckle, 28 May 2016 - 11:02 AM.
Posted 28 May 2016 - 10:57 PM
I've been consuming homebrew c60oo consisting of 1g SES 99.5% C60, generic filtered EVOO (think it was wal-mart brand... yuck), mixed using Turnbuckle's method - for about 1 year now. The 1g is about to run out, so I suspect average consumption of about 3mg/day. I am 28.
It's interesting, since I feel I have experienced inverse effects of C60 vs. what others report.
-Endurance: I have not noticed any increased endurance, and actually find myself skipping exercise more often than not because I am too tired to bother. Though, I am overweight, which I'm certain contributes (have been overweight since starting C60, not a new development)
-Sunburn: Have not spent enough time in the sun in the past year to really ever get properly roasted, but that is partly because I feel direct sunlight on my skin much more intensely than I believe I used to. Skin feels, subjectively, much more sensitive to UV and even brief exposure makes it sting worrisomely, like it is being permanently damaged. I feel photoaging/liver spots on my arms have increased significantly in the same time period as well, though I can't objectively a/b this.
-Graying: What prompted this post, actually: just this last month I have noticed my first gray hairs (quite a lot of them), showing up in a concentrated 2-inch patch on the top of my head. I think 28 is rather young to be starting to gray, and I don't know of any genetics in my family that would account for it. I don't recall any particular trauma to this part of the head, ever.
-Joints/Inflammation: I would say joint pain, especially knee pain, has increased over the last year, but I am significantly overweight so I'm more inclined to attribute it to this. I have mild rosacea that comes and goes, but has more often than usual been coming and staying around especially in the past 6 months.
Despite all this I still take it, as I am still convinced the benefits are largely invisible/long-term and all my observations are strictly conjectural. There are no acute negative or positive effects after ingestion, ever. I have not noticed any cognitive effects, positive or negative, ever.
Posted 28 May 2016 - 11:30 PM
I've been consuming homebrew c60oo consisting of 1g SES 99.5% C60, generic filtered EVOO (think it was wal-mart brand... yuck),
More than 60% of EVOO sold in the US is adulterated and not really EVOO. Worse, oils sold in grocery stores can be years old and rancid, so they are doing you more harm than good. I tried to sell a product to Wal Mart years ago and discovered they don't give a flip about quality, only price, so I would never buy olive oil from them.
See this thread in particular-- http://www.longecity...nol-hypothesis/
Edited by Turnbuckle, 28 May 2016 - 11:31 PM.
Posted 02 June 2016 - 08:59 PM
I just read this article on WorldHealth.net about c60. It's from 2004 so I would think people wouldn't still be using c60 if there was these concerns. Is there anyone more experienced on this subject who might give an opinion?
http://www.worldheal...all_but_deadly/
Posted 14 June 2016 - 11:37 PM
I've been out of the country for a couple of weeks, during which I didn't take much in the way of supplements. Now that I'm back I wanted to experiment with c60-OO from a cleaner slate.
I have noticed endurance benefits from 0.25 teaspoons (1.23 ml) per day over the past 2 days. Today I doubled that to 1/2 tsp with more benefits. I am using a high polyphenol olive oil and SES 99.95% c60 in a not quite saturated mix.
I have to wonder if there isn't a U-shaped response, as I have felt bad with larger doses.
Posted 15 June 2016 - 07:49 AM
I have noticed endurance benefits from 0.25 teaspoons (1.23 ml) per day over the past 2 days. Today I doubled that to 1/2 tsp with more benefits. I am using a high polyphenol olive oil and SES 99.95% c60 in a not quite saturated mix.
I have to wonder if there isn't a U-shaped response, as I have felt bad with larger doses.
I wonder the same thing. I now suspect my body aches may be explained by a sensitivity to excess HT.
What is the threshold where it starts to make you feel bad? What symptoms do you feel?
Edited by Empiricus, 15 June 2016 - 07:50 AM.
Posted 15 June 2016 - 12:53 PM
Just a blah, low energy feeling. My running suffers (average heart rate divided by average pace goes up). Keep in mind that I was taking other things at the time, so there could be other reasons.
I took my resting heart rate this morning as I was dozing and it was a nice 51 bpm, about 10 bpm lower than usual.
Posted 15 June 2016 - 08:18 PM
Posted 16 June 2016 - 10:28 AM
Just a blah, low energy feeling. My running suffers (average heart rate divided by average pace goes up). Keep in mind that I was taking other things at the time, so there could be other reasons.
I took my resting heart rate this morning as I was dozing and it was a nice 51 bpm, about 10 bpm lower than usual.
I have had the experience of lethargy in addition to body aches. And I've had the experience of c60 giving me endurance and strength. For me the dose may well be a factor. I'm not sure if it's the main one though as my reaction appears better or worse depending on the batch of c60 I'm taking.
Edited by Empiricus, 16 June 2016 - 10:31 AM.
Posted 16 June 2016 - 03:35 PM
Hello, I am having an adverse reaction with my pet rat and c60oo. It is easier for me to write in the first person so will be referring to my pet rat as "I". I am on day 3 of an adverse reaction related to an initial dose of c60oo. My mind is normally my greatest vanity, but due to what has been called brain fog on this topic, I am unable to pull my thoughts together.
On the evening of the 13th, I took 2 mg which I believed to be a safe initial dose. I noticed very little before going to bed except irritability. The next morning, I woke up with extreme 'brain fog ', but continued to pushed through my morning routine of supplements, adding them slowly over several hours to determine any effects.
After taking 500mg of NR, I began having wave-like feelings accompanied by sweating after which I did have some relief and clarity of mind. Then I felt what I would describe as a profound over reaction of the parasympathetic nervous system including extreme salivation and peristalsis. I feel like my body was having a difficult time maintaining homeostasis. I have had a similar, but less severe feeling after taking other substances which would cause an increase in metabolism. I normally have a body temperature of around 96.9-97.5 and have attributed this to a detox reaction regarding temperature dependent enzyme reactions becoming active(NR has a shortlived thermogenic effect on me which usually goes away, but the c60 is keeping my body temp closer to 99F) During one of the intense 'waves' I described before, I sprayed magnesium chloride on my skin as I was concerned about hypercalcemia with the parasympathetic response going crazy and seemed to give me a small amount of relief.(This may have just helped relax my freak out or it may be applicable to whomever mentioned the possibility of increased Ca uptake).
I could go on about these micro adjustments I attempted, but as of this morning I seem to have only brain fog and photophobia. I know someone has mentioned their cyp1a2 polymorphism and being 'refloxed' upon taking c60 and I am having very similar symptoms, I normally have great cyp1a2 metabolism as I love my coffee and smoke. However, I have been taking pterostibene and it is a strong inhibitor. I know this pathway affects the lipid walls of organelles, Ho-1 and heme, the handling of peroxides and ROS. I am considering taking a small dose of St John's wort to induce, but am unable in my current crippled condition, to think these things through completely. Part of me is raising a red flag about doing this, but I can't remember anything and my concentration is too poor to relearn anything right now.
Any advice on inducing/inhibiting this pathway would be appreciated.
Hello, I am having an adverse reaction with my pet rat and c60oo. It is easier for me to write in the first person so will be referring to my pet rat as "I". I am on day 3 of an adverse reaction related to an initial dose of c60oo. My mind is normally my greatest vanity, but due to what has been called brain fog on this topic, I am unable to pull my thoughts together.
On the evening of the 13th, I took 2 mg which I believed to be a safe initial dose. I noticed very little before going to bed except irritability. The next morning, I woke up with extreme 'brain fog ', but continued to pushed through my morning routine of supplements, adding them slowly over several hours to determine any effects.
After taking 500mg of NR, I began having wave-like feelings accompanied by sweating after which I did have some relief and clarity of mind. Then I felt what I would describe as a profound over reaction of the parasympathetic nervous system including extreme salivation and peristalsis. I feel like my body was having a difficult time maintaining homeostasis. I have had a similar, but less severe feeling after taking other substances which would cause an increase in metabolism. I normally have a body temperature of around 96.9-97.5 and have attributed this to a detox reaction regarding temperature dependent enzyme reactions becoming active(NR has a shortlived thermogenic effect on me which usually goes away, but the c60 is keeping my body temp closer to 99F) During one of the intense 'waves' I described before, I sprayed magnesium chloride on my skin as I was concerned about hypercalcemia with the parasympathetic response going crazy and seemed to give me a small amount of relief.(This may have just helped relax my freak out or it may be applicable to whomever mentioned the possibility of increased Ca uptake).
I could go on about these micro adjustments I attempted, but as of this morning I seem to have only brain fog and photophobia. I know someone has mentioned their cyp1a2 polymorphism and being 'refloxed' upon taking c60 and I am having very similar symptoms, I normally have great cyp1a2 metabolism as I love my coffee and smoke. However, I have been taking pterostibene and it is a strong inhibitor. I know this pathway affects the lipid walls of organelles, Ho-1 and heme, the handling of peroxides and ROS. I am considering taking a small dose of St John's wort to induce, but am unable in my current crippled condition, to think these things through completely. Part of me is raising a red flag about doing this, but I can't remember anything and my concentration is too poor to relearn anything right now.
Any advice on inducing/inhibiting this pathway would be appreciated.
Posted 16 June 2016 - 05:29 PM
After taking 500mg of NR, I began having wave-like feelings accompanied by sweating after which I did have some relief and clarity of mind. Then I felt what I would describe as a profound over reaction of the parasympathetic nervous system including extreme salivation and peristalsis. I feel like my body was having a difficult time maintaining homeostasis. I have had a similar, but less severe feeling after taking other substances which would cause an increase in metabolism. I normally have a body temperature of around 96.9-97.5 and have attributed this to a detox reaction regarding temperature dependent enzyme reactions becoming active(NR has a shortlived thermogenic effect on me which usually goes away, but the c60 is keeping my body temp closer to 99F) During one of the intense 'waves' I described before, I sprayed magnesium chloride on my skin as I was concerned about hypercalcemia with the parasympathetic response going crazy and seemed to give me a small amount of relief.(This may have just helped relax my freak out or it may be applicable to whomever mentioned the possibility of increased Ca uptake).
I had a rather negative reaction to taking 1 gram of niacin at about the same time as a dose of C60, so I would recommend that people don't mix C60 with NAD precursors such as niacin, nicotinamide or NR. At least one toxic interaction is known, quoted below. It's not at all clear how this could apply here, but it's also known that partially oxidized C60 is even more reactive, and this is likely present in most of the C60/EVOO being sold commercially, as exposure to visible light creates it.
Upon UVA irradiation, however, both C60 and NADH undergo photochemical reactions to produce O2(.-), which could lead to a possible synergistic toxicity effects. C60 photosensitization via Type-I pathway is not observed in the absence of reducing agents.
So, speculating here, UVA irradiation might not be necessary with C60 epoxide, and in the presence of NADH (the reduced form of NAD+), superoxide radicals could be formed, which would be more obvious when NAD precursors are taken. The presence of C60 epoxides in commercially sold C60/EVOO could at least partially explain how it is creating tumors in rats.
Thus note the following about commercially sold C60 products--
These individuals are able to purchase C60 from distributors who state it is “not for human consumption” but also describe many positive qualities allowing the purchaser to assume those benefits would be found in themselves as well. While initial research with C60 showed a reduction in tumor growth, the study Grohn conducted using commercially available C60 found a massive increase in tumor growth.
It's possible that antioxidant polyphenols in olive oil prevent or reduce the formation of epoxides, but unfortunately, these don't last that long--a few months and they will be greatly diminished, especially if oxygen is allowed to get in and the mix is not deaerated afterward. For my own use I have given up on olive oil and am now mixing C60 into MCT oil, adding in hydroxytyrosol (the major antioxidant found in olive oil) separately, then freezing it until I need it.
Edited by Turnbuckle, 16 June 2016 - 05:41 PM.
Posted 16 June 2016 - 09:23 PM
I had a rather negative reaction to taking 1 gram of niacin at about the same time as a dose of C60, so I would recommend that people don't mix C60 with NAD precursors such as niacin, nicotinamide or NR. At least one toxic interaction is known, quoted below. It's not at all clear how this could apply here, but it's also known that partially oxidized C60 is even more reactive, and this is likely present in most of the C60/EVOO being sold commercially, as exposure to visible light creates it.
Upon UVA irradiation, however, both C60 and NADH undergo photochemical reactions to produce O2(.-), which could lead to a possible synergistic toxicity effects. C60 photosensitization via Type-I pathway is not observed in the absence of reducing agents.
So, speculating here, UVA irradiation might not be necessary with C60 epoxide, and in the presence of NADH (the reduced form of NAD+), superoxide radicals could be formed, which would be more obvious when NAD precursors are taken. The presence of C60 epoxides in commercially sold C60/EVOO could at least partially explain how it is creating tumors in rats.
Thus note the following about commercially sold C60 products--
How long do NAD precursors such as niacin, nicotinamide and NR stick around in the body? What are your thoughts as to how much time should pass after taking a dose of c60 before these are consumed. I'm also wondering how much time should elapse prior to a c60 dose if you've taken some.
Isn't it thought that c60 sticks around for quite a while? Like weeks? How is it even possible to avoid this interaction if you're taking c60?
Edited by Empiricus, 16 June 2016 - 09:32 PM.
Posted 16 June 2016 - 09:40 PM
I had a rather negative reaction to taking 1 gram of niacin at about the same time as a dose of C60, so I would recommend that people don't mix C60 with NAD precursors such as niacin, nicotinamide or NR. At least one toxic interaction is known, quoted below. It's not at all clear how this could apply here, but it's also known that partially oxidized C60 is even more reactive, and this is likely present in most of the C60/EVOO being sold commercially, as exposure to visible light creates it.
Upon UVA irradiation, however, both C60 and NADH undergo photochemical reactions to produce O2(.-), which could lead to a possible synergistic toxicity effects. C60 photosensitization via Type-I pathway is not observed in the absence of reducing agents.
So, speculating here, UVA irradiation might not be necessary with C60 epoxide, and in the presence of NADH (the reduced form of NAD+), superoxide radicals could be formed, which would be more obvious when NAD precursors are taken. The presence of C60 epoxides in commercially sold C60/EVOO could at least partially explain how it is creating tumors in rats.
Thus note the following about commercially sold C60 products--
How long do NAD precursors such as niacin, nicotinamide and NR stick around in the body? What are your thoughts as to how much time should pass after taking a dose of c60 before these are consumed? How much time should elapse prior to a c60 dose if you've taken some?
I don't know about NR, but for niacin and nicotinamide the times would be roughly half a day and a full day respectively. See Fig. 1. That's for taking them before C60. Doing it the other way there are no papers to go on, but from what cmpercell said above, he had a problem taking NR in the morning after taking C60 in the evening of the previous day. My own experience suggests a full day or two is good enough, though there's the possibility one could have a negative reaction that would be so minimal you wouldn't think it anything other than a random fluctuation. Likely the C60 mix has something to do with the time required. The more oxidized the mix, the more of a pro-oxidant it becomes in the presence of NADH, and thus the more time required. But that's speculative as I said before.
Edited by Turnbuckle, 16 June 2016 - 09:43 PM.
Posted 28 June 2016 - 05:17 PM
If C60OO reacted with NADH to create superoxide, that would seem to be a real problem, given that there's normally quite a bit of NADH in mitochondria, and we believe (or hope) that the C60OO ends up there.
In fact there should be way more NADH in the cells than one would take as a supplement at any time I'd guess.
Posted 28 June 2016 - 05:39 PM
If C60OO reacted with NADH to create superoxide, that would seem to be a real problem, given that there's normally quite a bit of NADH in mitochondria, and we believe (or hope) that the C60OO ends up there.
Why would c60oo react with NADH? Is there any evidence for this?
Posted 28 June 2016 - 09:28 PM
If C60OO reacted with NADH to create superoxide, that would seem to be a real problem, given that there's normally quite a bit of NADH in mitochondria, and we believe (or hope) that the C60OO ends up there.
Why would c60oo react with NADH? Is there any evidence for this?
That was in response to Turnbuckle's post above http://www.longecity...ndpost&p=778950
Posted 03 July 2016 - 12:22 PM
I had a rather negative reaction to taking 1 gram of niacin at about the same time as a dose of C60, so I would recommend that people don't mix C60 with NAD precursors such as niacin, nicotinamide or NR. At least one toxic interaction is known, quoted below. It's not at all clear how this could apply here, but it's also known that partially oxidized C60 is even more reactive, and this is likely present in most of the C60/EVOO being sold commercially, as exposure to visible light creates it.
Upon UVA irradiation, however, both C60 and NADH undergo photochemical reactions to produce O2(.-), which could lead to a possible synergistic toxicity effects. C60 photosensitization via Type-I pathway is not observed in the absence of reducing agents.
So, speculating here, UVA irradiation might not be necessary with C60 epoxide, and in the presence of NADH (the reduced form of NAD+), superoxide radicals could be formed, which would be more obvious when NAD precursors are taken. The presence of C60 epoxides in commercially sold C60/EVOO could at least partially explain how it is creating tumors in rats.
Thus note the following about commercially sold C60 products--
How long do NAD precursors such as niacin, nicotinamide and NR stick around in the body? What are your thoughts as to how much time should pass after taking a dose of c60 before these are consumed? How much time should elapse prior to a c60 dose if you've taken some?
I don't know about NR, but for niacin and nicotinamide the times would be roughly half a day and a full day respectively. See Fig. 1. That's for taking them before C60. Doing it the other way there are no papers to go on, but from what cmpercell said above, he had a problem taking NR in the morning after taking C60 in the evening of the previous day. My own experience suggests a full day or two is good enough, though there's the possibility one could have a negative reaction that would be so minimal you wouldn't think it anything other than a random fluctuation. Likely the C60 mix has something to do with the time required. The more oxidized the mix, the more of a pro-oxidant it becomes in the presence of NADH, and thus the more time required. But that's speculative as I said before.
As I described here, after being off c60 for 2 weeks, I took 125-250 mg daily of NR and little else for 6 days and felt incredibly alert and energetic and needed hardly any sleep. I was absolutely astounded. On the whole, the positive results I was getting met or exceeded the most positive reports I've seen reported for NR at such low doses over such a short time. I experienced some foot pain, however.
I discontinued NR on the 6th day and evening took PQQ that evening. Next morning I took 2mg of C60. On the evening of the 9th day I took about 60 mg of NR sublingually. Woke up with sore feet. From day 10 to 14, I took 125-250 mg of NR. The foot pain issue worsened considerably and all the positive benefits I had experienced the previous week were greatly diminished, at times hardly perceptible. On evening of day 14, I took PQQ before a run in the evening. On morning of day 15 I felt agitated and couldn't focus.
I suspect the c60 may have had something to do with the much diminished effects of NR I experienced in week 2.
There's also the foot pain issue. Several people at Longecity have reported foot pain on NR (though at much higher doses) yet when I search Amazon reviews, I can't find one report of this symptom. Perhaps the people reporting feet pain on NR are all taking c60...
It's apparent by the foot pain that I've reached a dead end with NR. My plan is to stay away from c60 for a few weeks and then retry the NR and see.
Edited by Empiricus, 03 July 2016 - 12:38 PM.
Posted 03 July 2016 - 01:08 PM
Like I said it could be any one of those things in my stack, or none of those things.
Still on the same stack plus Quercetin now. I did increase the pterostilbene/resveratrol dose after reading about its effects on the brain. I have essential tremor, trying everything I can to combat it and so far nothing works.
I don't experience any foot pain.
I don't know if C60OO is helping me, hurting me, or doing nothing at all. I'm not experiencing anything negative though, not sure if anything positive is happening though I still feel that energy on most days, I need to drop most everything in my stack and figure out what it is. I'm taking 80mg of C60OO over 5 days and then breaking for a couple of weeks in between.
Edited by Nate-2004, 03 July 2016 - 01:08 PM.
Posted 03 July 2016 - 02:22 PM
There's also the foot pain issue. Several people at Longecity have reported foot pain on NR (though at much higher doses) yet when I search Amazon reviews, I can't find one report of this symptom. Perhaps the people reporting feet pain on NR are all taking c60...
It's apparent by the foot pain that I've reached a dead end with NR. My plan is to stay away from c60 for a few weeks and then retry the NR and see.
Perhaps C60 had nothing directly to do with it. Perhaps it was hyperuricemia--
Drug-induced gout.AbstractA number of pharmacological agents can induce hyperuricaemia, and sometimes gout, usually by interfering with the renal tubular excretion of urate but also in some instances by increasing the formation of uric acid. Alcohol is well known to have this property and in recent years diuretic-induced hyperuricaemia has become a global phenomenon. Other drugs which can cause hyperuricaemia are salicylates, pyrazinamide, ethambutol, nicotinic acid, cyclosporin, 2-ethylamino-1,3,4-thiadiazole, fructose and cytotoxic agents. A special type of 'drug-induced gout' can follow the rapid lowering of serum uric acid by allopurinol or uricosuric drugs.http://www.ncbi.nlm..../pubmed/2070427
It's possible that NR will have the same effect.
Posted 03 July 2016 - 05:13 PM
There's also the foot pain issue. Several people at Longecity have reported foot pain on NR (though at much higher doses) yet when I search Amazon reviews, I can't find one report of this symptom. Perhaps the people reporting feet pain on NR are all taking c60...
It's apparent by the foot pain that I've reached a dead end with NR. My plan is to stay away from c60 for a few weeks and then retry the NR and see.
Perhaps C60 had nothing directly to do with it. Perhaps it was hyperuricemia--
Drug-induced gout.AbstractA number of pharmacological agents can induce hyperuricaemia, and sometimes gout, usually by interfering with the renal tubular excretion of urate but also in some instances by increasing the formation of uric acid. Alcohol is well known to have this property and in recent years diuretic-induced hyperuricaemia has become a global phenomenon. Other drugs which can cause hyperuricaemia are salicylates, pyrazinamide, ethambutol, nicotinic acid, cyclosporin, 2-ethylamino-1,3,4-thiadiazole, fructose and cytotoxic agents. A special type of 'drug-induced gout' can follow the rapid lowering of serum uric acid by allopurinol or uricosuric drugs.http://www.ncbi.nlm..../pubmed/2070427
It's possible that NR will have the same effect.
That's interesting. Thank you. I have experienced what seems to be gout now and again, but only in my big toe. This new pain is confined to the arch of my foot. Can you think of anything I could try taking with the NR that might mitigate the gout, if that's what it is?
Edited by Empiricus, 03 July 2016 - 05:16 PM.
Posted 04 July 2016 - 06:36 PM
Please see this update from Kmoody regarding a possible cause of the apparent toxicity found in the SES C60oo they tested:
http://www.longecity...e-2#entry781237
Posted 04 July 2016 - 07:59 PM
There's also the foot pain issue. Several people at Longecity have reported foot pain on NR (though at much higher doses) yet when I search Amazon reviews, I can't find one report of this symptom. Perhaps the people reporting feet pain on NR are all taking c60...
It's apparent by the foot pain that I've reached a dead end with NR. My plan is to stay away from c60 for a few weeks and then retry the NR and see.
Perhaps C60 had nothing directly to do with it. Perhaps it was hyperuricemia--
Drug-induced gout.AbstractA number of pharmacological agents can induce hyperuricaemia, and sometimes gout, usually by interfering with the renal tubular excretion of urate but also in some instances by increasing the formation of uric acid. Alcohol is well known to have this property and in recent years diuretic-induced hyperuricaemia has become a global phenomenon. Other drugs which can cause hyperuricaemia are salicylates, pyrazinamide, ethambutol, nicotinic acid, cyclosporin, 2-ethylamino-1,3,4-thiadiazole, fructose and cytotoxic agents. A special type of 'drug-induced gout' can follow the rapid lowering of serum uric acid by allopurinol or uricosuric drugs.http://www.ncbi.nlm..../pubmed/2070427
It's possible that NR will have the same effect.
That's interesting. Thank you. I have experienced what seems to be gout now and again, but only in my big toe. This new pain is confined to the arch of my foot. Can you think of anything I could try taking with the NR that might mitigate the gout, if that's what it is?
You could try Montmorency 100% tart cherry concentrate, which is available from grocery stores.
Posted 06 July 2016 - 02:32 PM
You could try Montmorency 100% tart cherry concentrate, which is available from grocery stores.
Which vendor do you buy for hydroxytyrosol? Do you think it would work for C60 in EVOO too?
I've used a product called Olea25, which is oleuropein extracted from olive leaves and then converted into HT at a 25% concentration. The claim is that all the oleuropein is converted, but the content of the residual 75% is not stated. At least three vendors are selling it on Amazon in caps and I expect all contain the same product. I've mixed it into EVOO with no problem. Olive oil has HT already, but generally at low concentrations. See this thread.
Edited by Turnbuckle, 06 July 2016 - 02:35 PM.
Posted 06 July 2016 - 02:52 PM
You could try Montmorency 100% tart cherry concentrate, which is available from grocery stores.
Which vendor do you buy for hydroxytyrosol? Do you think it would work for C60 in EVOO too?
I've used a product called Olea25, which is oleuropein extracted from olive leaves and then converted into HT at a 25% concentration. The claim is that all the oleuropein is converted, but the content of the residual 75% is not stated. At least three vendors are selling it on Amazon in caps and I expect all contain the same product. I've mixed it into EVOO with no problem. Olive oil has HT already, but generally at low concentrations. See this thread.
Then, you just open capsules, and pour it to an amber bottle with C60EVOO? How many mg do you put(assuming whole content contains 25% of HT) per 100ml of C60 EVOO?
Is this brand what you've used?(https://www.amazon.c...keywords=olea25)
You seem to not worry about excipients.
Edited by Graviton, 06 July 2016 - 02:58 PM.
Posted 09 July 2016 - 06:00 PM
It's been 1 year since my first dose of c60. I've seen a variety of effects, both adverse and positive. My total intake must be in the vicinity of 60 mg. I always spaced the doses 1 week apart. I've taken several breaks from c60 ranging from 2 weeks to longer than a month. Here I'm listing perceived effects by formulation that I think are likely attributable to the c60 formulation.
Commercial c60: first 2 months @ 1 mg/wk, next 2 months @ 2.5 mg/wk, last month @ 5 mg/wk
(+) shiny hair, mulit-colored hair, hard nails, breath holding easier, exercise endurance boost lasting 2 days, didn't get sick during this time.
(-) pain in lower back for weeks (5 mg dose only)
Commercial c60 + olive leaf extract: 3 weeks @ 1.5 mg/week
(+) none
(-) pain in lower back for weeks, got sick
Homemade HT enriched c60 from recent harvest: 4 weeks @ 2-5 mg/week
(+) huge improvement in complexion lasting 2 days
(-) pain in back for weeks, anxiety lasting 1 day, physical lethargy lasting 1 day, possible adverse interaction with NR or PQQ, remained sick
Homemade c60 from recent harvest: 4 weeks @ 2-5 mg/week
(+) exercise endurance boost lasting 2 days
(-) nails hard but flaky, possible adverse interaction with NR
Other observations: Mild blurry vision after doses sometimes that seems to go away, definitely my hair grows faster. Grey hair has increased this year (from almost none to noticeable), developed chronic cough in March that has improved greatly but not gone away yet.
Questions: One thing I'm looking into is whether I may have developed a sensitivity to olive products. Possibly I'm more sensitive to other supplements as well, but I'm not sure which ones. Anyway, something sets off the lower back aches I attribute to c60 when I'm off c60 now and I'm not quite sure what. I think eating olives or using olive oil might be what does it.
Edited by Empiricus, 09 July 2016 - 06:20 PM.
Posted 09 July 2016 - 06:29 PM
Thank you Empiricus for that report. My observations are for only 6 weeks (I did not take records, so this is just from memory) of taking commercial c60oo about every other day at at 1 mg or less per dose, some days I would forget. Before starting c60oo, both of my feet hurt after walking on them just a few blocks, the right one from previous surgery and the left from mild plantar fasciitis. This has been ongoing for over two years. Also a finger joint constantly hurt from arthritis for the last 1 1/2 years. After a month on this regimen I noticed I no longer hurt anywhere. I connected the arthritic finger joint improvement to the c60oo because I also put it on the joint directly but for some reason just thought my feet had gotten better finally on their own. I decided to stop using c6oo until further testing could be done on it after reading Kmoodys report. To my dismay both feet and finger joint pain returned within about 3 weeks. I did notice my lower back/kidney area hurt after starting c60oo but it hurts sometimes anyway so that is not a reliable report. I thought about continuing use of the product on the finger joint directly to see if it would again help but reports of degradation by light stops me from doing that.
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