Hello, I am having an adverse reaction with my pet rat and c60oo. It is easier for me to write in the first person so will be referring to my pet rat as "I". I am on day 3 of an adverse reaction related to an initial dose of c60oo. My mind is normally my greatest vanity, but due to what has been called brain fog on this topic, I am unable to pull my thoughts together.
On the evening of the 13th, I took 2 mg which I believed to be a safe initial dose. I noticed very little before going to bed except irritability. The next morning, I woke up with extreme 'brain fog ', but continued to pushed through my morning routine of supplements, adding them slowly over several hours to determine any effects.
After taking 500mg of NR, I began having wave-like feelings accompanied by sweating after which I did have some relief and clarity of mind. Then I felt what I would describe as a profound over reaction of the parasympathetic nervous system including extreme salivation and peristalsis. I feel like my body was having a difficult time maintaining homeostasis. I have had a similar, but less severe feeling after taking other substances which would cause an increase in metabolism. I normally have a body temperature of around 96.9-97.5 and have attributed this to a detox reaction regarding temperature dependent enzyme reactions becoming active(NR has a shortlived thermogenic effect on me which usually goes away, but the c60 is keeping my body temp closer to 99F) During one of the intense 'waves' I described before, I sprayed magnesium chloride on my skin as I was concerned about hypercalcemia with the parasympathetic response going crazy and seemed to give me a small amount of relief.(This may have just helped relax my freak out or it may be applicable to whomever mentioned the possibility of increased Ca uptake).
I could go on about these micro adjustments I attempted, but as of this morning I seem to have only brain fog and photophobia. I know someone has mentioned their cyp1a2 polymorphism and being 'refloxed' upon taking c60 and I am having very similar symptoms, I normally have great cyp1a2 metabolism as I love my coffee and smoke. However, I have been taking pterostibene and it is a strong inhibitor. I know this pathway affects the lipid walls of organelles, Ho-1 and heme, the handling of peroxides and ROS. I am considering taking a small dose of St John's wort to induce, but am unable in my current crippled condition, to think these things through completely. Part of me is raising a red flag about doing this, but I can't remember anything and my concentration is too poor to relearn anything right now.
Any advice on inducing/inhibiting this pathway would be appreciated.
Hello, I am having an adverse reaction with my pet rat and c60oo. It is easier for me to write in the first person so will be referring to my pet rat as "I". I am on day 3 of an adverse reaction related to an initial dose of c60oo. My mind is normally my greatest vanity, but due to what has been called brain fog on this topic, I am unable to pull my thoughts together.
On the evening of the 13th, I took 2 mg which I believed to be a safe initial dose. I noticed very little before going to bed except irritability. The next morning, I woke up with extreme 'brain fog ', but continued to pushed through my morning routine of supplements, adding them slowly over several hours to determine any effects.
After taking 500mg of NR, I began having wave-like feelings accompanied by sweating after which I did have some relief and clarity of mind. Then I felt what I would describe as a profound over reaction of the parasympathetic nervous system including extreme salivation and peristalsis. I feel like my body was having a difficult time maintaining homeostasis. I have had a similar, but less severe feeling after taking other substances which would cause an increase in metabolism. I normally have a body temperature of around 96.9-97.5 and have attributed this to a detox reaction regarding temperature dependent enzyme reactions becoming active(NR has a shortlived thermogenic effect on me which usually goes away, but the c60 is keeping my body temp closer to 99F) During one of the intense 'waves' I described before, I sprayed magnesium chloride on my skin as I was concerned about hypercalcemia with the parasympathetic response going crazy and seemed to give me a small amount of relief.(This may have just helped relax my freak out or it may be applicable to whomever mentioned the possibility of increased Ca uptake).
I could go on about these micro adjustments I attempted, but as of this morning I seem to have only brain fog and photophobia. I know someone has mentioned their cyp1a2 polymorphism and being 'refloxed' upon taking c60 and I am having very similar symptoms, I normally have great cyp1a2 metabolism as I love my coffee and smoke. However, I have been taking pterostibene and it is a strong inhibitor. I know this pathway affects the lipid walls of organelles, Ho-1 and heme, the handling of peroxides and ROS. I am considering taking a small dose of St John's wort to induce, but am unable in my current crippled condition, to think these things through completely. Part of me is raising a red flag about doing this, but I can't remember anything and my concentration is too poor to relearn anything right now.
Any advice on inducing/inhibiting this pathway would be appreciated.