• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans
  • .org
  • Districts
  • Media
  • SupportUs
  • Collaborate
  • Contact
  • Search
  • Join

Photo
* * * * - 14 votes

C60 experiments @ home

Started by LeonardElijah , Apr 17 2012 02:13 AM
buckyball c60 fullerene buckyballs

  • Please log in to reply
3585 replies to this topic

#2551 Andey

  • Guest
  • 673 posts
  • 203 ₮
  • Location:Kiev, Ukraine

Posted 07 August 2013 - 05:36 PM

Thanks for sharing

#2552 ambivalent

  • Guest
  • 758 posts
  • 177 ₮
  • Location:uk
  • NO

Posted 07 August 2013 - 06:07 PM

control images (they are all labelled by time, just mouse over the ones that don't give a timestamp in the picture) .

Attached Files


Edited by ambivalent, 07 August 2013 - 06:09 PM.

Click HERE to rent this advertising spot for C60 HEALTH to support Longecity (this will replace the google ad above).

#2553 ambivalent

  • Guest
  • 758 posts
  • 177 ₮
  • Location:uk
  • NO

Posted 07 August 2013 - 08:48 PM

Well no shortage of data then! I think the distinct difference between the healing of the control and the c60 is very clear. The final picture taken today shows how prominent the colouring still is (or can be at times, it is typically much paler). Just below, near the wrist, you might make out the shadow of the control burn which is now around 30 days old, but has changed little in the last couple of weeks.

'pre c60' corresponds to the larger burn on the right of the two occurring 1 hour before the first administration of c60; 'post c60' naturally corresponds to the burn three hours after the c60 was administered. Once again the images are labelled, so mouse-over where it is unclear when on the timeline the image was taken.

[you're welcome Andey]

Attached Files


Edited by ambivalent, 07 August 2013 - 09:48 PM.

#2554 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 07 August 2013 - 10:28 PM

I think the sun and using sections of the skin permitted light to come through might be a little easier to judge C60s effects. One area can be pre c60 and then taking c60 and a day or two later do the sun test area again somewhere else. Now when I got the burns it was following taking by a day or two say a quarter of a teaspoon of oil for the first time, and then the same type of burn on one day after the other burn but separate hands and locations on them. Pain was very intense for about 4 hours, and then faded to nothing not even soreness nor tingling, which was nothing like I had seen before nor experienced. Though I have to admit I never remember burning myself before with the flame of a propane torch.

My theory is that the C60 prevented a lot of ROS reaction that takes place and that this limited the damage and at the same time allowed a funny healing process to take place, but ONLY because it was there hours or days before the burns. Now I did burn the back of my hand a few weeks later on the top of a hot oven, and it reacted a little different. The pain left in hours like before and no blistering or really redness, but it got to a plastic rough type state, and it seems to have just stop there and there is discolouration though mild there. It is right on top of a large blood vessel.

This summer, as pale as a ghost to start, no sun burn even out in the New Mexico 95 or more heat for hours. Now, not quite so weird because I learned a long time ago 1000s of ius of E and some grams of C could give me quite a lot burn protection from the sun.

My best guess is a lot of secondary damage when events happen are being blocked or absorbed by the C60, if present before the event by hours or days and a lot more than a few drops.

#2555 ambivalent

  • Guest
  • 758 posts
  • 177 ₮
  • Location:uk
  • NO

Posted 07 August 2013 - 10:40 PM

Thanks free10 (not free1!) - I'm actually less keen to test myself burning in the sun, I've a fair few moles - its unclear the nature of c60s protection from burning. If it does require build up of c60 over a period time to harness its effect then that maybe something I'd consider testing in the future. But I remain convinced there has been a real effect here with c60, I don't understand it, but it is very strange. The first and third burns were very similar and yet they have healed completely differently.

#2556 hav

  • Guest
  • 1,089 posts
  • 219 ₮
  • Location:Cape Cod, MA
  • NO

Posted 08 August 2013 - 05:44 PM

I don't use c60/oo on my skin but I do take a fairly high oral dose: 36 mg once every 2 weeks. Anyway, I was mowing the lawn in the early afternoon last month and it was pretty hot out, in the 90's, and I was sweating so much I took my shirt off. I was out there a little longer than I planned pulling crabgrass, around 2 hours or so I think, and my back and shoulders got some serious sunburn. Which took the better part of 3 weeks for the burning sensation to subside. I'm can't remember sunburn ever taking that long to heal on me before, usually more like a day or 2 at the most, but the last time I ever had a burn that needed any healing was over 40 years ago. In the distant past, once I acclimated to the sun, I was pretty much immune to burning. In this incident I didn't really get any burn on my face, arms, or legs, which were probably pretty acclimated, but I guess my back and shoulders were not previously exposed much. Treated the back and shoulders with Aloe Vera at night and suntan lotion during the day and have experienced only slight peeling. Don't know if c60 prevented it from being worse but I don't think I'll be letting that happen again anytime soon.

Howard

Edited by hav, 08 August 2013 - 05:45 PM.

#2557 ambivalent

  • Guest
  • 758 posts
  • 177 ₮
  • Location:uk
  • NO

Posted 08 August 2013 - 06:24 PM

free10: I was on the very sleepy when I started reading your post last night and so I didn't respond fully. I would certainly concur that the
tingling sensation seemed to disappear more quickly than expected. Interestingly, too, your descrption of the healing process getting stuck chimes with my experience. It is very odd. I did feel there was no discernable difference between the responses of the injury shortly before or just a couple of hours after the administration of c60. So if there was a c60 effect on my injury then it didn't need to resident days beforehand - in this case.

hav: Well that certainly conflicts with much of the anecdotal evidence of sunburns. Also, it seems you weren't spared any pain or discomofort either.

I will update on the progress (I took around 5mg today, my highest dose). I'm not expecting the burn marks to disappear anytime soon but the skin does look healthy. Free10 Is there much/any scarring from the propane torch?

Edited by ambivalent, 08 August 2013 - 06:26 PM.

#2558 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 29 August 2013 - 07:07 PM

free10: I was on the very sleepy when I started reading your post last night and so I didn't respond fully. I would certainly concur that the
tingling sensation seemed to disappear more quickly than expected. Interestingly, too, your descrption of the healing process getting stuck chimes with my experience. It is very odd. I did feel there was no discernable difference between the responses of the injury shortly before or just a couple of hours after the administration of c60. So if there was a c60 effect on my injury then it didn't need to resident days beforehand - in this case.

hav: Well that certainly conflicts with much of the anecdotal evidence of sunburns. Also, it seems you weren't spared any pain or discomofort either.

I will update on the progress (I took around 5mg today, my highest dose). I'm not expecting the burn marks to disappear anytime soon but the skin does look healthy. Free10 Is there much/any scarring from the propane torch?



No scarring on the palm of the hands burned by the propane torch flame, that I can see easily. The location on the right hand was on the large part or muscle, by the thumb. That area where I burned looks slightly pinker than the area around it and that's it. Now I did suffer a burn on the back of the left hand a few weeks or more later when my hand slipped and touch the top of the inside of my oven around 400 degrees for a split second. It acted the same as the other two burns at first, with pain for 4 hours and then the pain leaving quickly, and no blistering. But the second part where the skin turned plastic like and peeled off a week or two later never happened with it, and there does look like there is slight discolouration there of a reddish brown. I am 65 and the skin is different as you age, in the way it behaves and looks.

Now, a mini report from my recent bi annual physical at the VA in Aug 2013. I started C60-OO around the first part of February 2013 and laid off the TA65, to trial more just the C60 than the two combined. My check up, which included blood work showed my LDL dropped like a rock, and so did the triglycerides which have been high for decades. My total cholesterol was 174. My kidney and liver functions were great (great is his term), and so were my electrolytes. He checked my carotid and said it sounded good and lungs and heard some noise, but they have been shot for years and not so bad now.He wanted to see how the swelling in my legs and feet were and I told him basically it was gone and said you are right, when he just got a glimpse of my lower calf for a second on my left leg. I think the reduced swelling happened, because I could be a lot more active this summer.

The only two negatives was a higher PSA with an increase in prostate size, and my red blood cells are to high again and need to be drained off. It was last done about 18 months ago and normally he said every 4-6 months it would be needed. I think since starting the C60 I have notice a rise in hormones and that could have caused the increase in prostate size, and a jump in PSA. I have had prostate problems since the 90s on and off, and used an herb to knock it back down in the past. In a month he wants to recheck the PSA number.

All in all he seemed a little shocked to see how well I was doing and how the lab numbers looked. I told him about the C60, but he knows I am crazy anyway and I warned him from the start years back i would not be his normal patient. I started back on the TA65 chemical, along with the C60-OO now. I take them, at the same time every other day for now. He said whatever I was doing keep doing it.

#2559 NDM

  • Guest
  • 343 posts
  • 7 ₮
  • Location:North America

Posted 30 August 2013 - 11:46 PM

Why on earth would C60 dramatically lower LDL and triglycerides? By what mechanism?

#2560 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 31 August 2013 - 12:56 AM

Why on earth would C60 dramatically lower LDL and triglycerides? By what mechanism?



I believe LDL is oxidised cholesterol and C60 is a powerful antioxidant, and on triglycerides I have no idea. My triglycerides have been high for decades. All I know is they both dropped like a rock. The only other change in the last 6 months I made was also taking some krill oil and Astaxanthin every so often (not daily). I smoke over a pack a day.

#2561 niner

  • Guest
  • 16,276 posts
  • 1,999 ₮
  • Location:Philadelphia

Posted 31 August 2013 - 01:07 AM

I'm pretty sure that other c60 users have seen little or no change, or at least not permanent change, in blood lipids. In about a week I should have a new set of lipid results- I hope things are remarkably better, but I'm not holding my breath.

#2562 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 31 August 2013 - 02:14 AM

I'm pretty sure that other c60 users have seen little or no change, or at least not permanent change, in blood lipids. In about a week I should have a new set of lipid results- I hope things are remarkably better, but I'm not holding my breath.



When I was decades younger it might not have with me either as my numbers were quite good, except for high triglycerides even then and now I have O2 levels from the mid to high 80s to mid 90s on finger pulse monitors, plus smoking so I am probably a walking free radical zone. I wasn't expecting C60 to change the numbers really and who knows maybe it was for some other reason, or a strange lab artefact. If I wanted to change those number I would lean more towards grams of niacin and C per day plus a tablespoon or two of metamucil (fiber). I use that in the late 80s to improve the blood fat numbers pretty fast inside 6 weeks. My total fats dropped to 160 then and stayed there for maybe 15 years even when I stopped taking them.

Remember too I am a person who has taken the TA65 chemical on and off since 2011, and though not taking most of 2013 while taking the C60OO the stem cells might have gotten younger and be producing younger and healthier new replacement cells.

What I can tell you is I have sensed a hormone change it seems, since taking the C60 and this summer I got a ton more work done as I improved in strength and energy. about 18 months ago I was in a VA hospital in a wheel chair with Ataxia cause unknown, and was barely able to walk still 6 weeks later. When I got there I couldn't even sit up on the side of the bed without falling over. If I stood the muscles in my legs could suddenly loose the communication with the brain and relax, and down I would go leaving me hanging by my arms gripping a grab bar.

My ability to stand and walk out of there 6 weeks later and go home seemed to surprise them and I haven't fallen since, though I have stumbled a few times more than normal. At the same time as the Ataxia I got neuropathy head to toe, and now it is mainly in my legs and feet, with sometimes just in my feet. Started the TA 65 chemical every few days once I got home, and then ran out about the same time as starting the C60OO in the first part of Feb 2013. Now doing both every other day after the labs.

VA rates me 100% on COPD and 60% on spine (AS) in 2006. I probably should have gotten 100% on each then. This is not what most taking it situation is here I don't think, and I have been seeing functional improvements. For me, the labs were just a side note I thought I should throw in to the pile of what is going on with me on C60OO. I do have labs going back in time and may be able to post them next week when I get online access to them, just to add to the pile.

Edited by free10, 31 August 2013 - 02:16 AM.

#2563 Hebbeh

  • Guest
  • 1,661 posts
  • 571 ₮
  • Location:x

Posted 31 August 2013 - 02:47 AM

FWIW...I've been using C60/EVOO for 14 months now and have had 3 blood tests in that time frame and 1 blood test about 10 days before starting C60 in June 2012. My Cholesterol hasn't changed much with TC ranging from 137-141 mg/dL, LDL 59-77, and HDL 52-60 during this time frame. However, my triglycerides have dropped from 114 mg/dL before C60 to 52 on the first test after C60, 51 on the second, and now the really weird part....on the test I had a couple weeks ago, I was supposed to go in fasted, which I was except I had forgotten about the test until I got into work and saw it on my calendar and had taken a morning dose of 10ml of C60/EVOO containing 6.6 mg C60. Anyway, running over to the clinic and getting a blood draw less than an hour after the 10ml of C60/EVOO, I expected my trigs to be elevated from the EVOO....however, later they called and said that the machine was unable to even measure my trigs and I would need to schedule another draw....which I haven't had time to do. I'm not sure how low my trigs would of been for the machine to be unable to measure them.

#2564 smithx

  • Guest
  • 1,446 posts
  • 458 ₮

Posted 31 August 2013 - 09:35 AM

This is very curious.

I haven't researched it (yet). Is there a problem if triglycerides go too low?

I know that super low cholesterol is supposed to be bad for various reasons including spontaneous cerebral hemorrhage.

#2565 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 31 August 2013 - 09:52 AM

This is very curious.

I haven't researched it (yet). Is there a problem if triglycerides go too low?

I know that super low cholesterol is supposed to be bad for various reasons including spontaneous cerebral hemorrhage.



With a very quick look nothing I could find, and they say

What is Too Low?



  • Triglyceride levels of less than 50 are rare but still considered healthy. If a triglyceride reading is less than 35, that may indicate an underlying health problem.
Causes of Low Triglycerides



  • Several factors can cause excessively low triglycerides: hyperthyroidism, an extremely low fat diet, some medications, and any health condition that causes poor absorption of nutrients or malnutrition.
Treatment for Low Triglycerides



  • The treatment for low triglycerides usually involves treating the underlying problem--for instance treating hyperthyroidism, changing medications or eating a more balanced diet.
You have to understand these quacks do not really know what they are doing, and them, and their patients, and families all wind up dead. They are little more than pill pushers at best.

#2566 Hebbeh

  • Guest
  • 1,661 posts
  • 571 ₮
  • Location:x

Posted 31 August 2013 - 11:13 AM

Quick background...
56 years old...
5'10", 148 lbs, lean and athletic....less than 10% body fat as measured both by calipers and tanita bioimpedance scale...and maintained through exercise (resistance and aerobic) and strict diet consisting of 2400 cal (+/- depending on activity) higher protein, moderate carb, moderate good fat.

No prescription meds. Normal thyroid...TSH in lower range and don't have any symptoms to indicate otherwise. No serious underlying health conditions I'm aware of.

Like a lot of people here, I take a laundry list of supplements...and always looking to experiment with the next big "discovery". My favorites are of course C60, resveratrol, uridine...but I've got a list of others like many other people are doing.

I don't recall if I went for a run the night before as I don't keep a log anymore...I just go when I have the time and energy...and the length of the session depends on the same....I let my body decide.

edit...forgot about fish oil....I cut back with the recent study...but take 3g regular, 2g high DPA, 1g krill, and 1g concentrated cod liver....I like my omega 3's. I also take quite a bit of lecithin...a spoonful of sunflower lecithin granules couple times a day with a handful of various supps.

Edited by Hebbeh, 31 August 2013 - 11:24 AM.

  • like x 1

#2567 NDM

  • Guest
  • 343 posts
  • 7 ₮
  • Location:North America

Posted 31 August 2013 - 11:15 PM

Would it be possible that C60 interferes with the test measuring triglycerides whereas the underlying level of triglycerides in the body is actually unaffected?
  • like x 1

#2568 xEva

  • Guest
  • 1,594 posts
  • 24 ₮
  • Location:USA
  • NO

Posted 31 August 2013 - 11:46 PM

NDM beat me to it. How are trigs measured by that machine? -- and what if "the underlying level of triglycerides in the body is actually" increased? But the test won't show it.

#2569 Turnbuckle

  • Location:USA
  • NO

Posted 01 September 2013 - 10:19 PM

Would it be possible that C60 interferes with the test measuring triglycerides whereas the underlying level of triglycerides in the body is actually unaffected?


If it's not a spurious result due to its effect on the test itself, then it may point to C60's mode of action. Triglycerides are metabolized in the mitochondria, and the first step is to get them past the outer membrane, which is accomplished with carnitine palmitoyltransferase. This is thought to be the rate-limiting step. Deficiencies can cause things like type II diabetes and elevated triglycerides.

The next step is beta-oxidation, and C60 might conceivably have some influence there too.
  • like x 1

#2570 mikey

  • Guest
  • 987 posts
  • 171 ₮
  • Location:USA
  • NO

Posted 02 September 2013 - 06:03 AM

I'm pretty sure that other c60 users have seen little or no change, or at least not permanent change, in blood lipids. In about a week I should have a new set of lipid results- I hope things are remarkably better, but I'm not holding my breath.


I may be mistaken, but where C60 has publications that show it protecting from UV and radiation, antiviral, anti-Alzheimer's, anti-cancer, immune-stimulating, hair-growing, etc...

as was said in the Introduction to "The prolongation of the lifespan of rats by repeated oral administration of [60]
fullerene" ---

"...UV and radioprotection [3], antiviral, antioxidant, and anti-amyloid activities [1,4e7], allergic response [8] and angiogenesis
[9] inhibitions, immune stimulating and antitumour effects [10,11], enhancing effect on neurite outgrowth [12], gene delivery
[13], and even hair-growing activity [14]."

-- I haven't seen published data that it improves cardiovascular functions. Has anyone?

It certainly hasn't seemed to changed my blood lipids and I have had two VAP tests since I started taking it a year ago.

I wish that it did.

The only way I that could lower LDL-C was to cut the heck out of carbs and take lots of niacin and some other supplements.

#2571 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 02 September 2013 - 07:24 AM

I'm pretty sure that other c60 users have seen little or no change, or at least not permanent change, in blood lipids. In about a week I should have a new set of lipid results- I hope things are remarkably better, but I'm not holding my breath.


I may be mistaken, but where C60 has publications that show it protecting from UV and radiation, antiviral, anti-Alzheimer's, anti-cancer, immune-stimulating, hair-growing, etc...

as was said in the Introduction to "The prolongation of the lifespan of rats by repeated oral administration of [60]
fullerene" ---

"...UV and radioprotection [3], antiviral, antioxidant, and anti-amyloid activities [1,4e7], allergic response [8] and angiogenesis
[9] inhibitions, immune stimulating and antitumour effects [10,11], enhancing effect on neurite outgrowth [12], gene delivery
[13], and even hair-growing activity [14]."

-- I haven't seen published data that it improves cardiovascular functions. Has anyone?

It certainly hasn't seemed to changed my blood lipids and I have had two VAP tests since I started taking it a year ago.

I wish that it did.

The only way I that could lower LDL-C was to cut the heck out of carbs and take lots of niacin and some other supplements.



I wasn't expecting a nice drop in lipids especially the ugly ones, but in a way not surprised either. Taking grams of niacin or C have been shown to do the same, so it is not exactly unheard of and C60 is known to have a lot of power in many ways. It is just this one might be a new one. Might being the keyword here.

While not exactly being anti cancer unless light is shined on it, which you have to admit is a little weird itself, it is not exactly cancer friendly.

http://www.electroch...1/pdfs/1004.pdf

Of course that's in water, and in different substances it might become less, or more friendly to cancers but I don't see them being big buddies ever.

#2572 hav

  • Guest
  • 1,089 posts
  • 219 ₮
  • Location:Cape Cod, MA
  • NO

Posted 02 September 2013 - 07:40 PM

Right after my c60 loading period last year my triglyceride levels jumped up a bit.

Attached File  hv_lipids.jpg   46.22KB   15 downloads

My situation is probably not typical, however. I've had to take statins for over 10 years to control my levels. I was taking atorvastatin when I started c60/oo at a loading dosage of 45 ml a day for about a month in when I got the blood test in June of 2012. Since I was in the c60/oo loading period and ingesting allot of olive oil, a rise in triglycerides seemed reasonable.

I've been on a new statin for a while now and will probably retest soon. I expect the triglyceride levels will be closer to where they used to be now that I'm only taking the c60/oo once every 2 weeks.

Howard

#2573 Turnbuckle

  • Location:USA
  • NO

Posted 02 September 2013 - 08:20 PM

Right after my c60 loading period last year my triglyceride levels jumped up a bit.

Attached File  hv_lipids.jpg   46.22KB   15 downloads

My situation is probably not typical, however. I've had to take statins for over 10 years to control my levels. I was taking atorvastatin when I started c60/oo at a loading dosage of 45 ml a day for about a month in when I got the blood test in June of 2012. Since I was in the c60/oo loading period and ingesting allot of olive oil, a rise in triglycerides seemed reasonable.

I've been on a new statin for a while now and will probably retest soon. I expect the triglyceride levels will be closer to where they used to be now that I'm only taking the c60/oo once every 2 weeks.

Howard



I'm not sure if taking C60 while on stains is meaningful. Statins may be harming your mitochondria more than C60 is helping.

#2574 mikey

  • Guest
  • 987 posts
  • 171 ₮
  • Location:USA
  • NO

Posted 02 September 2013 - 09:44 PM

Right after my c60 loading period last year my triglyceride levels jumped up a bit.

Attached File  hv_lipids.jpg   46.22KB   15 downloads

My situation is probably not typical, however. I've had to take statins for over 10 years to control my levels. I was taking atorvastatin when I started c60/oo at a loading dosage of 45 ml a day for about a month in when I got the blood test in June of 2012. Since I was in the c60/oo loading period and ingesting allot of olive oil, a rise in triglycerides seemed reasonable.

I've been on a new statin for a while now and will probably retest soon. I expect the triglyceride levels will be closer to where they used to be now that I'm only taking the c60/oo once every 2 weeks.

Howard



I'm not sure if taking C60 while on stains is meaningful. Statins may be harming your mitochondria more than C60 is helping.


First, olive oil doesn't raise triglycerides. It reduces them.

Have you looked at what might be causing elevated blood lipids that your doctor prescribed statins for?

It's generally consuming too many carbohydrate calories.

Turnbuckle's report, last year, on the damage that statins did to his mitochondria made me investigate that, and it's true, statins do permanent damage to mitos.

See Graveline's book, The Statin Damage Crisis - http://www.amazon.co...k/dp/B0041D9F8A

My LDL-C and Lp(a) jumped recently and my doctor was insistent that I start a statin.

I will never take statins, so I've cut carbs way down, increased niacin to 3 g/day, am taking high doses of policosanol, plant sterols and pantethine - which all have published data showing efficacy - and am going to re-do blood tests in a month to see if I've improved my lipid profile.

Familial genetics predict that I will have CVD, however, I see no reason that I can't change the situation by being aggressive in attacking CVD with science-based natural therapies AND changes in my dietary practices.

My relatives that died of CVD all consumed far too many carb calories. Lots of bread, grains, chips, some Pepsi, just bad "foods."

Consuming too any carb calories predicts elevated LDL, etc...

This is where I see no benefit from taking C60oo. It hasn't changed anything that I can see in my cardiovascular profile.

My HDL and triglycerides are fine.

I have been taking 4,000 mg of EPA/DHA omega-3's (fish oil)/day for 10+ years - it stops my atrial fibrillation - and triglycerides typically measure 70.

Unless one has severe genetically caused CVD, reducing carb intake should alter blood lipids significantly.

#2575 hav

  • Guest
  • 1,089 posts
  • 219 ₮
  • Location:Cape Cod, MA
  • NO

Posted 03 September 2013 - 05:27 AM

Right after my c60 loading period last year my triglyceride levels jumped up a bit.

Attached File  hv_lipids.jpg   46.22KB   15 downloads

My situation is probably not typical, however. I've had to take statins for over 10 years to control my levels. I was taking atorvastatin when I started c60/oo at a loading dosage of 45 ml a day for about a month in when I got the blood test in June of 2012. Since I was in the c60/oo loading period and ingesting allot of olive oil, a rise in triglycerides seemed reasonable.

I've been on a new statin for a while now and will probably retest soon. I expect the triglyceride levels will be closer to where they used to be now that I'm only taking the c60/oo once every 2 weeks.

Howard



I'm not sure if taking C60 while on stains is meaningful. Statins may be harming your mitochondria more than C60 is helping.


I've noticed there's some disagreement on the possible relationship between statin usage and cancer risk. Most studies show that statin usage reduces risk of breast and prostate cancer. But I saw a recent one on breast cancer that found long term statin use by women may increase their risk by a factor of 1.83. Given that none of the cancer-prone Baati rats that were given c60 died with any trace of cancer, an effect rate far in excess of 1.83, I'd say that c60 anti-cancer effects have a reasonable likelihood of outweighing possible cancer-related negative effects of statins. But it would take a c60/statin shootout study to know for sure.

Howard

#2576 free10

  • Guest
  • 152 posts
  • 15 ₮
  • Location:US

Posted 03 September 2013 - 06:20 AM

High Dose Simvastatin Slows Brain Atrophy and Delays Disability in Secondary Progressive Multiple Sclerosis


http://www.neurology...tracts/PL02.001
Statins may prevent aging and extend lifespan

http://insidecostari...xtend-lifespan/

Edited by free10, 03 September 2013 - 06:29 AM.

#2577 markymark

  • Guest
  • 188 posts
  • 18 ₮
  • Location:Europe
  • NO

Posted 03 September 2013 - 06:36 AM

Hello Howard an all,

I honestly do not want to open up the too-much-statins-are-prescribed box. However everybody who has been told by their MDs to take a statin should ask about the NNT (number needed to treat) of statins. OK, with respect to primary prevention, there are groups, which may profit from statins: relatively young men (40-65) with a mid to high risk (PROCAM or Framingham Scores) for myocardial infarction and alike.
Here is information about the NNT in primary prevention
http://www.thennt.co...-heart-disease/
Here the same for secondary prevention.
As an MD/Internist I do prescribe them, but sometimes only 5 mg Atorvastatin or 10 mg together with supplements (Q10, creatine, Vit D, to avoid muscle damage) and exercise and life style measures we all know about here, might be enough to do the trick (i.e. to move away from ones personal risk). Exercise confers about the same degree of risk reduction of coronary events, as prescription drugs do, i.e. about 20-30 %.
I'd love to see C60-oo studies in animal models of atherosclerosis and who knows, we, the big rats may live to see such experiments once being done and published.
best MM

#2578 hav

  • Guest
  • 1,089 posts
  • 219 ₮
  • Location:Cape Cod, MA
  • NO

Posted 05 September 2013 - 03:53 AM

Hi, markymark. Being a reluctant statin user, I've done quite a bit of reading on it. The main documented negatives are the muscle issues you mention as well as a negative impact on cognition. I've personally experienced both of those negative effects. You might notice that the comparative annual lipid panel test results I posted earlier, before and after starting c60/oo, were from the Summer of 2011 and 2012. I also got tested earlier this past summer, after taking a shot at discontinuing statins to see what would happen. I was hoping maybe c60/oo might minimize my need to take them. I'm away from home at the moment so I cannot post those exact test results but they were bad enough to convince me to resume with a different statin.

One of the things I discovered in my reading was that the incidence of negative muscle and cognition effects from statins is pretty low. Making me unlucky, I guess. But for those experiencing negative effects, there seems to be a positive correlation with the lipid solubility of particular statins, with water-soluble/lipid-insoluble statins pretty much free of those negative effects. Which should be expected regarding freedom from cognition effects since a lipid insoluble statin should be unable to cross the bbb. Unfortunately, however, the water soluble statins aren't as effective at lowering cholesterol levels. The statin I'm trying now, livalo, has the lowest lipid solubility of the lipid-soluble bunch and hopefully will be the least likely of the effective statins to have those negative effects. So far I have not experienced the negative cognition effects from it but it may be too soon to tell... I've only been on it about 2 months. I also supplement with d3 (plus k2), coq10, and nac, which seemed to help only minimally while I took lipitor, but seem much more effective with livalo. Also, pqq was totally devoid of any cognitive effect I could perceive while taking lipitor. So I gave up on it. But I gave pqq another shot a few weeks ago and I can sense a positive effect from it now.

Howard

#2579 markymark

  • Guest
  • 188 posts
  • 18 ₮
  • Location:Europe
  • NO

Posted 05 September 2013 - 02:01 PM

Hi Howard, yes,it was a good move to turn towards the more water soluble statins.
Maybe consider genetic testing: http://www.mayomedic...nt.php?id=20269 (this test is only for simvastatin-users). I must admitt that, due to lack of time, I am not at the cutting edge of knowledge of genetic testing for the predisposition of statin myopathy and other complications (mental etc.)
maybe check this out: http://jeffreydachmd...ns-disbeliever/
Supplementing with d3 (plus k2), coq10, and nac is also wise if a person is on statins.
So I wish you good luck and don't forget to exercise (cardio - and resistance training). This is at least as effective as any cardio-prescription drug. But I know that you know this...
And fortunately, C60 might enables us to exercise on a higher level.
MM

Edited by markymark, 05 September 2013 - 02:07 PM.

#2580 niner

  • Guest
  • 16,276 posts
  • 1,999 ₮
  • Location:Philadelphia

Posted 05 September 2013 - 02:52 PM

Maybe consider genetic testing: http://www.mayomedic...nt.php?id=20269 (this test is only for simvastatin-users). I


If you have 23AndMe, (now only $99- quite a deal, IMHO) you can get this result by browsing your raw data and looking up the SNP rs4149056 in the gene SLC01B1. Having CC in this position dramatically increases your chances of myopathy. As it happens, I'm TT, but still had some mild myopathy from Lipitor, which I quit in short order.
Back to C60Oil



Also tagged with one or more of these keywords: buckyball, c60, fullerene, buckyballs

49 user(s) are reading this topic

0 members, 49 guests, 0 anonymous users

  1. LONGECITY
  2. → Science & Health
  3. → Supplements
  4. → C60Oil
  5. site rules