3585 replies to this topic

[HighDesertWizard]

In the Markovic C60 Review (Biomaterials 2008) posted above by Metrodorus, it said the following:

Surprisingly, C3 regioisomer of tris-malonic C60
derivative was more efficient cytoprotective agent than corresponding
D3 isomer, despite their similar ability for ROS deactivation
and probably due to the better incorporation of the C3
isomer into the lipid membranes [130,140]. This interesting observation
indicates that the overall cytoprotective activity of C60 derivatives
will not only depend on their ROS-scavenging capacity, but
also on the strength of their interaction with cellular membranes.

I think that this is a large part of the OO/C60 effect. The long chain fatty acid adducts should be uniquely suited to localizing the C60 in the mitochondrial membane, and I think that is the essence of the observed effect in rats.

TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L).

Reactive oxygen species (ROS) produced by tumor necrosis factor-alpha (TNF-alpha) have an important function in cell death by activating c-Jun N-terminal kinase. However, the exact mechanism of mitochondrial ROS production, after TNF-alpha stimulation, is not clearly understood. In this study, we determined that ROS modulator 1 (Romo1) and B-cell lymphoma-extra large (Bcl-X(L)) are directly associated with TNF-alpha-induced ROS production. In response to TNF-alpha, TNF complex II, which consists of receptor-interacting protein 1, TNF receptor-associated protein with death domain, TNF receptor-associated factor 2, Fas-associated death domain protein, and pro-caspase-8, binds to the C-terminus of Romo1 located in the mitochondria. Concurrently, Romo1 recruits Bcl-X(L) to reduce the mitochondrial membrane potential, resulting in ROS production and apoptotic cell death. On the basis of these results, we suggest that Romo1 is a molecular bridge between TNF-alpha signaling and the mitochondria for ROS production that triggers TNF-alpha-mediated apoptosis, as well as a novel target in the development of anti-inflammatory agents that block the origin of ROS production.

wccaguy, on 27 May 2012 - 04:10 PM, said:

When radical life extension is a reality, all the scientifically credible schools of thought about aging will be be able to point to actual evidence and say "see, I told ya so."

Edited by wccaguy, 16 June 2012 - 10:58 PM.

[Metrodorus]

Hi niner, I noted that remark about cell membrane incorporation as well, and thought about your recent post on the matter.
Like you, I suspect this is an important aspect of the mechanism.

Simply keeping cells in a younger metabolic state - if this is indeed what happens, would be sufficient to help deprive tumors of their fuel, as they feed off senescent cells. This is partially why cancer is mostly a disease of old age.
http://www.newswise....-and-metastasis

[daouda]

Hi all

I have been suffering from a partly-delayed long-term adverse reaction to prolonged Fluoroquinolone antibiotics "therapy" for about 10 months now (last dose of FQ 10 months ago).
While I have improved a great deal since the "acute" phase, a lot of more or less debilitating symptoms remain and I still suffer from mild flare ups randomly

My remaining symptoms/damage are :

-tendinopathies/arthralgias all over but predominantly in achilles tendons, fingers, right shoulder and both knees (now have bilateral patellofemoral syndrome with grade 2 patellar chondropathies). Pain under right foot also, especially when walking barefoot. Joints cracking and popping (even those that never used to do this before)
-very tender spot in some muscles (more diffuse than trigger points). Also lots of trigger points and adhesions.
-random fasciculations of random muscles
-almost permanent crawling/buzzing sensation under skin at the calves (looking attentively you can see actually a lot of micro-fasciculations all over the calves)
-peripheral neuropathies, most notable being ulnar neuritis, with fingers often numb upon waking up
-"pressure" eye pain (waxing and waning but mostly resolved) and (sometimes severely) dry eyes (less and less often). Now 100% resolved : intense focusing (vision) issues (lasted a few months)
-many floaters in the eyes, increased photosensitivity, very marked increase in post-LASIK vision issues (starbursts and halos, loss of contrast sensitivity = messed up night vision)
-"brain fog" (sometimes intense), depersonalization/derealization (much better now, sometimes flares up but much less intense)
-IBS / intolerance to previously perfectly tolerated foods
-Impaired blood flow (almost perfect now, but was having abnormally cold hands and feet this winter)
-Intense muscle soreness following even light exercise
-Psoriasis-like dermatitis on the scalp (which disappears for a while after aplication of...vinegar! Then it comes back...)
-Much less energy...
-Vertical nail ridges (which I didnt have before, I was observing them since its an effect reported by many FQ ADR victims, they set in almost suddendly in about 1.5 months after the last FQ dose). Interesting to note that most of my older smoker friends have these and its also a known effect of Raynaud's (a lot of the FQ damages are beleived to be caused or amplified by ischemia of the finer blood vessels)
-Facial skin obviously less smooth/toned/elastic, suddendly aged appearance (happened almost suddendly about 2.5 months ago). (I hope this one is the fruit of my imagination, I dont dare asking ppl about it...)
I was a VERY athletic and strong 34 y.o. male before this, addicted to intense sports and never spending a single day without physical activity (and my knees had NEVER bothered me even when running, dancing, jumping or front-squatting 130kgs ass-to-grass). I am now a mere shadow of my pre-FQ self, weak and fragile, and feel like as if I had aged 30 years in 6 months.

Several ppl in this forum have had similar unfortunate experiences with FQ :
http://www.longecity...ience-very-bad/
http://www.longecity...olone-toxicity/

Now it's thought that FQ are able to cause all these effects primarily by screwing with mitochondrial DNA

from http://www.ncbi.nlm....pubmed/10216214
"Damage to mitochondrial DNA induced by the quinolone Bay y 3118 in embryonic turkey liver."
"Quinolones are a class of antibiotics that induce damage to and loss of DNA from bacteria. The structural organization of bacterial DNA is more similar to eukaryotic mitochondrial DNA (mtDNA) than to eukaryotic chromosomal or nuclear DNA (nDNA). Antibiotics affecting the bacterial genome may therefore preferentially damage mtDNA rather than nDNA"

http://www.ncbi.nlm..../pubmed/8440750
4-Quinolones cause a selective loss of mitochondrial DNA from mouse L1210 leukemia cells.

http://www.ncbi.nlm....les/PMC1797653/
Influence on Mitochondria and Cytotoxicity of Different Antibiotics Administered in High Concentrations on Primary Human Osteoblasts and Cell Lines

http://www.ncbi.nlm....pubmed/11195848
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.

So with all this talk about C60 rejuvenating mitochondria in some way I had to try this...
BTW Im not so surprised that a mitochondria-rejuvenating substance can have amazingly positive effects overnight (and sustained), when a mitochondria-damaging substance can conversely have amazingly devastating and sustained effects overnight too! Some ppl have had even much worse symptoms than me from a SINGLE dose of Levaquin or other FQ antibiotic that settled in with great severity a few hours later then kept worsening for MONTHS (even sometimes culminating in death after years of pain and invalidity) after that unique, single dose! Just do a "fluoroquinolone adverse reaction" search on google, there are MANY, MANY nightmare stories... I am actually among the "luckyer" ones...

So I ordered a few bottles from the european lady that has been posting in this very thread...
My plan is to take 2 tablespoons the first day (like jg) then around 2mg worth of c60 the next days for about ten days... Then maybe wait a couple weeks, or less, or more, and resume with the same protocol with or without the initial "loading" dose... Depending on what deductions for an optimal dosing protocol will have emerged from the brilliant minds here.

I will keep you posted about the results (will probably start a thread for this). I'm not expecting any kind of miracle but obviously cannot help having great hopes in this experiment.. Any degree of improvement of any of the above conditions will be more than welcome...


EDIT :
C60, FQ and ROS : it is beleived by some that FQ keep damaging ppl long after the last dose because they remain for a very long time in some tissues (they do penetrate deep, hence their indication in prostatitis and bone infection. It is nown that the similar chloroquine remains for years in the cornea too). So any antioxidant property is potentially useful even long after discontinuation of the drug


http://www.ncbi.nlm....les/PMC1426460/
Involvement of Reactive Oxygen Species in the Action of Ciprofloxacin against Escherichia coli

http://www.ncbi.nlm....pubmed/14569066
In vitro discrimination of fluoroquinolones toxicity on tendon cells: involvement of oxidative stress.

Edited by daouda, 17 June 2012 - 12:05 AM.

[NewtonPulsifer]

I've been reading more on C60 and lipid peroxidation. I found an interesting 1999 paper. It's a great read, as it goes into detail on their experiments into how C60 has such great characteristics to act as an antioxidant in a lipid membrane.

 

C(60) and water-soluble fullerene derivatives as antioxidants against radical-initiated lipid peroxidation.

http://ntur.lib.ntu....172028/1/37.pdf

What particularly piqued my interest was where it spoke about chain propagation of unsaturated lipids (pg 2). Apparently peroxidation of unsaturated fats happens as a chain reaction until stopped.

 

Wikipedia: Lipid Peroxidation

http://en.wikipedia....id_peroxidation

So oxidation can continue in a destructive chain reaction until stopped, which especially happens with polyunsaturated lipids (but also monounsaturated).

Another interesting read is how much better C3C60 was vs. D3C60, and even Vitamin E. Antioxidants like Vitamin E and Superoxide Dismutase are basically limited in their effectiveness by their diffusion throughout the medium - "diffusion-controlled". C3C60 was *not* (pg 5) - it did better than the diffusion-controlled rate. The paper writers hypothesized that this was due to crucial difference in polarity of the antioxidants and the crucial step of terminating the lipid peroxidation chain propagation.

It's still a mystery as to exactly how persistent the C60 is in the mitochondrial membrane. If the radionucleide C14 had a half life of 10-14 days in previous tests where it was being recycled in the new mitochondria being formed, I'd hazard a guess that the C60 might last a similar amount of time. It might be prudent to top off with an new dose every 10-14 days indefinitely.

[Rob Wegner]

This could be useful:

What is the Material Safety Data Sheet (MSDS) for Carbon 60?

[Turnbuckle]

Another update. I haven't taken C60 in a while but the effects not only persist but continue to get better. I saw a relative that I have seen in months and she was amazed at how young I looked. I asked if there was anything in particular and she said your hair, your skin, everything. In fact, the bald spot that began to develop in my twenties is now officially gone. The hair is thinner back there than in other areas, but if this continues I will have hair like Stalin's...to steal a line from Seinfeld.

[tweedlover]

That's truly amazing Turnbuckle - so brave of you and others on this forum to take a chance on a new substance and I'm really happy it seems to be paying off.

Have you been taking any photos to document the changes? A before and after bald spot shot would really have some impact Also, how's your dog doing - is he still more lively?

[daouda]

Turnbuckle, could you please sum up with some degree of detail the dosage(s) of C60 youve been taking and the timing/schedule of administrations? How long have you been off for? Thanks

[Turnbuckle]

That's truly amazing Turnbuckle - so brave of you and others on this forum to take a chance on a new substance and I'm really happy it seems to be paying off.

Have you been taking any photos to document the changes? A before and after bald spot shot would really have some impact Also, how's your dog doing - is he still more lively?

I haven't taken photos, but hair growth has been reported before. My dog that had the problem getting in the car is still doing fine weeks after getting a short regime of C60. He did have one day where he was having difficulty so I gave him a single dose of C60 and he hasn't a problem since.

[Turnbuckle]

Turnbuckle, could you please sum up with some degree of detail the dosage(s) of C60 youve been taking and the timing/schedule of administrations? How long have you been off for? Thanks

Here are a couple of reports I made previously about dosage--

http://www.longecity...724#entry515724

http://www.longecity...830#entry518830

[What'sAllThisThen]

Another update. I haven't taken C60 in a while but the effects not only persist but continue to get better. I saw a relative that I have seen in months and she was amazed at how young I looked. I asked if there was anything in particular and she said your hair, your skin, everything. In fact, the bald spot that began to develop in my twenties is now officially gone. The hair is thinner back there than in other areas, but if this continues I will have hair like Stalin's...to steal a line from Seinfeld.

No photos available, but can you elaborate on how severe your bald spot was and how relieved it is now? Was it completely bald, nothing but skin? How big was it? And how thin is it now?

[HighDesertWizard]

Assuming my hypothesis that C60 acts to strip methyl groups from the mitochondrial DNA is correct, then curcumin (which I've taken for some time) might act synergisticly--

Genomic DNA was extracted from a leukemia cell line exposed to curcuminoids at concentrations of 0, 1, 3, and 30 μM for 72 hours. Analyses of global DNA methylation levels showed stability at 1 μM curcumin, but decreased by approximately 15% to 20% at 3 μM and 30 μM curcumin compared with untreated basal methylation levels, which was equivalent to decitabine-induced decreases in global DNA methylation levels. These data show that curcumin is a potent DNA hypomethylating agent, which is consistent with its broad activity in inflammation, cancer, and many other diseases, while remaining relatively safe in normal healthy cells.

Development of curcumin as an epigenetic agent.

Turnbuckle... I have a couple questions about this earlier post.

• Curcumin has shown positive benefit to Genomic DNA and that means not mitochondrial DNA right?

• And it showed benefit as a hypomethylating agent, or so the study says, right?.

And then the study below too says that the powerfully beneficial herb Boswellia is also a demethylating agent vis-a-vis tumors.

As I recall it, the discussion had earlier thrown out the notion that C60 could have a positive impact because it was a hypomethylating agent. Well, now we have two examples of proven, profoundly healthful anti-inflammatory herbs that are hypomethylating agents. I think that question needs to be reopened.

http://www.ncbi.nlm....pubmed/22415137

Accumulating evidence suggests that chemopreventive effects of some dietary polyphenols in part may be mediated by their ability to influence epigenetic mechanisms in cancer cells. Boswellic acids, derived from the plant Boswellia serrata, have long been used for the treatment of various inflammatory diseases due to their potent anti-inflammatory activities. Recent preclinical studies have also suggested that this compound has anticancer potential against various malignancies. However, the precise molecular mechanisms underlying their anticancer effects remain elusive. Herein, we report that boswellic acids modulate the DNA methylation status of several tumor suppressor genes in colorectal cancer (CRC) cells. We treated RKO, SW48 and SW480 CRC cell lines with the active principle present in boswellic acids, acetyl-keto-β-boswellic acid (AKBA). Using genome-wide DNA methylation and gene expression microarray analyses, we discovered that AKBA induced a modest genome-wide demethylation that permitted simultaneous re-activation of the corresponding tumor suppressor genes. Quantitative methylation-specific PCR and RT-PCR validated the gene demethylation and re-expression of several putative tumor suppressor genes including SAMD14 and SMPD3. Furthermore, AKBA inhibited DNMT activity in CRC cells. Taken together, these results lend further support to the growing notion that the anticancer effect of boswellic acids in part may be due to its ability to demethylate and reactivate methylation-silenced tumor suppressor genes. These results suggest that boswellic acid might be a promising epigenetic modulator in the chemoprevention and treatment of CRC, and also provide a rationale for future investigations on the usefulness of such botanicals for epigenetic therapy in other human malignancies.

Edited by wccaguy, 17 June 2012 - 05:24 PM.

[Turnbuckle]

As I recall it, the discussion had earlier thrown out the notion that C60 could have a positive impact because it was a hypomethylating agent.

Some did. I didn't.

[Junk Master]

Turnbuckle, did you have any conversation with the group selling C60/OO before they used your testimonial from this site? Have you had any contact after?

[Turnbuckle]

Turnbuckle, did you have any conversation with the group selling C60/OO before they used your testimonial from this site? Have you had any contact after?

I noticed that one group is doing that and I said something about their dosing theory on one of the other threads. There was no contact whatsoever.

[niner]

I've been thinking a lot about this thread. We've really never had anything like this around here. It's kind of a weird feeling, knowing that we have on our hands an esoteric knowledge of the sort that people throughout history would have killed for or paid any amount of money for. And yet, this is essentially a public forum. Anyone in the world could come here and read this. Many have. Some of them are using Turnbuckle's words to sell product. Still, this is mostly under the radar. As far as I can tell, it hasn't hit the popular press in any big way. This state of affairs can't last forever; it will either bubble out into the popular consciousness or it will be "debunked".

Have any of you guys been talking to people about this, out in the world? I've told a few people, mostly close family and friends, but I've kept it pretty low key. I was just wondering what other people are doing. An odd thing occurred to me recently- You guys who have taken the plunge; you are no longer normal humans. Your biology is now changed to something beyond human. You might now be able to survive a dose of certain types of poisons (e.g. CCl4) that would kill a normal person. I don't know what else; it's uncharted territory.

[daouda]

Turnbuckle, have you noticed any change in sexual fonction, positive or negative (some beneficial, antiinflammatory/antioxidant stuff like curcumin or tea EGCG have anti-androgenic properties -by 5 alpha reductase inhibition or androgen receptor blunting - and dampen libido in some males)? Do you plan on doing some hormonal blood tests? I beleive no observation of the sexual behavior of the rats has been made in that study...

[Mind]

I've been thinking a lot about this thread. We've really never had anything like this around here. It's kind of a weird feeling, knowing that we have on our hands an esoteric knowledge of the sort that people throughout history would have killed for or paid any amount of money for. And yet, this is essentially a public forum. Anyone in the world could come here and read this. Many have. Some of them are using Turnbuckle's words to sell product. Still, this is mostly under the radar. As far as I can tell, it hasn't hit the popular press in any big way. This state of affairs can't last forever; it will either bubble out into the popular consciousness or it will be "debunked".

Have any of you guys been talking to people about this, out in the world? I've told a few people, mostly close family and friends, but I've kept it pretty low key. I was just wondering what other people are doing. An odd thing occurred to me recently- You guys who have taken the plunge; you are no longer normal humans. Your biology is now changed to something beyond human. You might now be able to survive a dose of certain types of poisons (e.g. CCl4) that would kill a normal person. I don't know what else; it's uncharted territory.

Many new people have come to Longecity because of this thread, but there has been no significant & noticeable increase in forum posting or registrations in the last few months. This is THE forum right now for C60 in Olive Oil. I would tend to think there would be more traffic and more chatter around it. Not yet. Perhaps it is a good thing. The further the investigation into C60 supplementation proceeds under the radar, the better wrt to government regulation. (IMO) If the FDA caught a whiff of this, they would shut it down in a heart-beat, fine and lock up everyone selling it, promoting it, discussing it, and then throw away the key (especially if it is beneficial for human health). Sounds outrageous, but remember this is the same organization that sends heavily armed SWAT teams to arrest Amish people for selling raw milk, and carried out a vindictive vendetta against LEF for many years.

[Raphy]

Many new people have come to Longecity because of this thread, but there has been no significant & noticeable increase in forum posting or registrations in the last few months. This is THE forum right now for C60 in Olive Oil. I would tend to think there would be more traffic and more chatter around it. Not yet. Perhaps it is a good thing. The further the investigation into C60 supplementation proceeds under the radar, the better wrt to government regulation. (IMO) If the FDA caught a whiff of this, they would shut it down in a heart-beat, fine and lock up everyone selling it, promoting it, discussing it, and then throw away the key (especially if it is beneficial for human health). Sounds outrageous, but remember this is the same organization that sends heavily armed SWAT teams to arrest Amish people for selling raw milk, and carried out a vindictive vendetta against LEF for many years.

+1

[SarahVaughter]

I would hate to be locked up :-(

Just for the record, we sold a very modest amount of C60 in olive oil so far (just a couple of liters), and we have a much more extensive site than "Carbon", our only competitor so far. If sales continue as they are now (and we had a spike followed by very slow sales), it will take a year before we recoup our investment (we bought two centrifuges, three filter columns, two vacuum pumps, 250 g of C60, eight magnetic stirrers, eight overhead stirrers and a mountain of glassware, plus lab furniture, filters and the good lord knows what else.)

Edited by SarahVaughter, 17 June 2012 - 09:52 PM.

[Turnbuckle]

Turnbuckle, have you noticed any change in sexual fonction, positive or negative (some beneficial, antiinflammatory/antioxidant stuff like curcumin or tea EGCG have anti-androgenic properties -by 5 alpha reductase inhibition or androgen receptor blunting - and dampen libido in some males)? Do you plan on doing some hormonal blood tests? I beleive no observation of the sexual behavior of the rats has been made in that study...

Hey, isn't it enough that it gives you good hair?

[SarahVaughter]

Just to dispel any notion that Turnbuckle and us are in collusion, I put on the record that we (Vaughter Wellness / owndoc.com / Sarah Vaughter) do not believe that the beneficial effects he reported here are a result of him taking the C60 in oil. In my opinion, it is very most likely a Placebo effect.

People should not have too high hopes of C60. Especially when you are ill, and especially when you suffer from ALS, do not purchase our C60 in olive oil. We think that the only thing one could reasonably expect of this product is a moderately longer lifespan and a certain degree of preventative effect against cancer.

That's all. Personally, I would only buy it if I were in my forties or above, and/or at risk for, or afraid of cancer. And only if I could well afford it.

[daouda]

Turnbuckle, have you noticed any change in sexual fonction, positive or negative (some beneficial, antiinflammatory/antioxidant stuff like curcumin or tea EGCG have anti-androgenic properties -by 5 alpha reductase inhibition or androgen receptor blunting - and dampen libido in some males)? Do you plan on doing some hormonal blood tests? I beleive no observation of the sexual behavior of the rats has been made in that study...

Hey, isn't it enough that it gives you good hair?

Precisely, finasteride gives ppl good hair and destroy the sexual lives of some of them. Go to propeciahelp.com and you will find hundreds of young males than will gladly give all of their hair for a reestablished manhood.

A lot of pro-hair substances achieve this effect by anti-androgenic actions . Propecia/Finasteride (5AR inhibitor, thus anti-DHT) being the most potent/worst offender. Finasteride was primarily indicated for benign prostate hyperplasia (an androgen-sensitive disease).

So, my question was very serious, and if you feel able to report anything on that front I would really appreciate.

Edited by daouda, 17 June 2012 - 11:13 PM.

[Junk Master]

Sarah, as far as recouping your investment, I'd focus your marketing on non-longevity related benefits. Turnbuckle is exactly right when he says, "Hey, isn't it enough that it gives you good hair," because good hair would be enough for a billion dollar market worldwide, as evidenced by Rogaine's 700 million dollar U.S. sales.

Again, if the product produced even a 5% increase in Vo2Max it's use would sweep the sporting/fitness industry and would also be a multi-billion dollar market.

Unfortunately, if it did cause any issues with libido, then all bets are off.

It certainly is exciting to be in on the "ground floor" so to speak, of what could be the first big deal supplement since Reservatrol...IMO.

[Turnbuckle]

Turnbuckle, have you noticed any change in sexual fonction, positive or negative (some beneficial, antiinflammatory/antioxidant stuff like curcumin or tea EGCG have anti-androgenic properties -by 5 alpha reductase inhibition or androgen receptor blunting - and dampen libido in some males)? Do you plan on doing some hormonal blood tests? I beleive no observation of the sexual behavior of the rats has been made in that study...

Hey, isn't it enough that it gives you good hair?

Precisely, finasteride gives ppl good hair and destroy the sexual lives of some of them. Go to propeciahelp.com and you will find hundreds of young males than will gladly give all of their hair for a reestablished manhood.

I've been taking finasteride for a few years without problem. Of course, it hasn't given me good hair, but it did keep if from falling out. So I suppose that if a short course of C60 were effective and without side effects it would blow finasteride (and all those other things that only half-way work) out of the water. And as it doesn't seem to work hormonally, I wouldn't expect any side effects and haven't seen any. I've already cut the finasteride back to twice a week and haven't seen anything falling out, so next I will stop it altogether.

Edited by Turnbuckle, 17 June 2012 - 11:14 PM.

[maxwatt]

Best to use it while it still works . I am still not wholly comfortable with the study, there are some issues that will not be settled until it is replicated.

In the meantime, My 25 pound terrier, age 14, almost blind and partly deaf, has received five doses of C60 in olive oil, (three of 3.2 mg, 2 of 4 mg). She is still as blind and deaf as before, and frequently seems disoriented. But others have notice she has more energy and is interacting with people more than previously. She is not eager for two mile walks as was our custom until she turned 13, but she stays outside longer before heading inside to sleep some more. The improvement we've noted could be normal remission, or an owner's placebo effect, or possibly an improvement in her state. I wouldn't expect much from any intervention at a human equivalent age of 98, but at least it hasn't killed her. I will continue to report if anything changes.

Edited by maxwatt, 18 June 2012 - 12:25 AM.

[Anthony_Loera]

Turnbuckle, have you noticed any change in sexual fonction, positive or negative (some beneficial, antiinflammatory/antioxidant stuff like curcumin or tea EGCG have anti-androgenic properties -by 5 alpha reductase inhibition or androgen receptor blunting - and dampen libido in some males)? Do you plan on doing some hormonal blood tests? I beleive no observation of the sexual behavior of the rats has been made in that study...

Hey, isn't it enough that it gives you good hair?

I don't know about Turnbuckle, but I have not had any "adverse" effects in that area... if anything, I have had some repeat dreams of Angelina Jolie and Jennifer Anniston taking an interest in me...

(I admit, I think it started when I saw that silly "Horrible Bosses" flick the other night...)








I am off to take a shot for the day, cheers!

A

Edited by Anthony_Loera, 18 June 2012 - 12:44 AM.

[Metrodorus]

Nice (2008) fullerene review article here.


Twenty years of promises: Fullerene in medicinal chemistry

[PDF] from 141.105.33.55
T Ros - … Chemistry and Pharmacological Potential of Fullerenes …, 2008 - Springer

[Anthony_Loera]

Hey Anthony,
When will it be available?

I will be at an Expo in Las Vegas looking for something at the end of the month... Hopefully it helps us here at RevGenetics manufacture a product that is more affordable than what is currently being offered with other folks.

Personally I would like to have something by the time August rolls around.

Cheers
A

[Metrodorus]

http://smarteconomy....owth-by-60.html


Interesting effects of fullerene solutions on plant growth.....