3585 replies to this topic

[Logic]

I dont mind the taste at all, but others here do.
Whats it take to encapsulate oil?

[mikey]

I did the Spectracell test and I feel that it was nonsense. All it told me was that I was 59, which is my chronological age. People guess me as being in my early 40's. See my pictures in my profile. (I just started uploading them.)

You feel it was nonsense because it gave your age exactly? Unless they already knew your age, the test sounds pretty accurate.

They knew my age.

[niner]

By the way, I kept wondering why Anthony kept posting 'recipes' with his C60oo. I took mine for the first time yesterday, and whoa... I just realized that I do not like olive oil. I had to put it in bread and eat it. I felt more like a lab rat.

Olive oil flavors are all over the map. Try to find an olive oil store that allows tasting, and find one you like. Arbequinas are popular. I like an oil that's robust without being bitter, which can be a little hard to find. I want a lot of polyphenols in my day to day oil, but for c60-oo, I really don't care. I do want it to taste ok, though.

[Turnbuckle]

I did the Spectracell test and I feel that it was nonsense. All it told me was that I was 59, which is my chronological age. People guess me as being in my early 40's. See my pictures in my profile. (I just started uploading them.)

You feel it was nonsense because it gave your age exactly? Unless they already knew your age, the test sounds pretty accurate.

They knew my age.

Good gimmick, guessing your age after they already know it.

[mikey]

Yes, but I've held the funniest funnies for now.
Lifelength lost my test for two months and then when found their doctor gave me the results that said I was 70 years old.

70 and still growing darker hair........... right!

Repeat Diagnostics' results should be coming soon.

We will see whether they have me as 59, 70, 110 or maybe I'll measure as dead.

[fntms]

The wart I was treating with C60OO is now gone...I rubbed/scratched it a bit during treatment to enhance C60OO penetration (there was some redness and inflammation from this).
The wart shrunk and yesterday I took off the remaining tiny bit. There was some bleeding.

Hope it doesn't grow again. I cut it off with a scalpel once a year ago and it did grow back.

I will continue with a drop of C60OO for a few days.

[smithx]

Yes, but I've held the funniest funnies for now.
Lifelength lost my test for two months and then when found their doctor gave me the results that said I was 70 years old.

70 and still growing darker hair........... right!

Repeat Diagnostics' results should be coming soon.

We will see whether they have me as 59, 70, 110 or maybe I'll measure as dead.

If two tests say that someone has short telomeres and one says they're longer, which test(s) would it make sense to believe?

If you pick the one you like better, that's something other than science.

[mikey]

At this point I am skeptical of both.
Now we will see what Repeat Diagnostics says. It's a more detailed test and Greenpower has some history with it, so it seems to be more credible.
But we shall see.

[Turnbuckle]

At this point I am skeptical of both.

You may discover that all of these tests are worthless.

[mikey]

Yes, but I've held the funniest funnies for now.
Lifelength lost my test for two months and then when found their doctor gave me the results that said I was 70 years old.

70 and still growing darker hair........... right!

Repeat Diagnostics' results should be coming soon.

We will see whether they have me as 59, 70, 110 or maybe I'll measure as dead.

If two tests say that someone has short telomeres and one says they're longer, which test(s) would it make sense to believe?

If you pick the one you like better, that's something other than science.

Yes, there you are again, being nasty and implying that I'm going to do something biased and "other than science."
Where do you get off being snotty like that?

And will you please refrain from involving me in your nasty attitude going forward?

[Kevnzworld]

At this point I am skeptical of both.

You may discover that all of these tests are worthless.

I did the 23 and me DNA test and it was very informative. It isn't a telomere test however.
They just lowered the price to $99

https://www.23andme.com/howitworks/

Edited by Kevnzworld, 12 December 2012 - 07:45 PM.

[Freebytes]

23andme just received something like $50M in funding. I wish they would offer telomere testing as well because I trust that company a lot more than some of the others.

[smithx]

If two tests say that someone has short telomeres and one says they're longer, which test(s) would it make sense to believe?

If you pick the one you like better, that's something other than science.

Yes, there you are again, being nasty and implying that I'm going to do something biased and "other than science."
Where do you get off being snotty like that?

And will you please refrain from involving me in your nasty attitude going forward?

It's not nasty. You're 59. One test said you were 59 the other said you were 70 in terms of your telomeres. You don't like either answer because you think you "look young" so you're searching for a company which will give you an answer you like.

That's not a reasonable way to do research, and in fact it clutters up this discussion with nonsense. This is a discussion about C60, not about how young you look or about your experiences with telomere testing companies. Please stay on topic. If you want to post messages about how young you look, please post in the appropriate forum, which would be this one: http://www.longecity.../274-skin-hair/

[mikey]

If two tests say that someone has short telomeres and one says they're longer, which test(s) would it make sense to believe?

If you pick the one you like better, that's something other than science.

Yes, there you are again, being nasty and implying that I'm going to do something biased and "other than science."
Where do you get off being snotty like that?

And will you please refrain from involving me in your nasty attitude going forward?

It's not nasty. You're 59. One test said you were 59 the other said you were 70 in terms of your telomeres. You don't like either answer because you think you "look young" so you're searching for a company which will give you an answer you like.

That's not a reasonable way to do research, and in fact it clutters up this discussion with nonsense. This is a discussion about C60, not about how young you look or about your experiences with telomere testing companies. Please stay on topic. If you want to post messages about how young you look, please post in the appropriate forum, which would be this one: http://www.longecity.../274-skin-hair/

You don't even know when you're being snotty. Zero humility on your part or you'd admit it when you're a snot.

I'm not posting about how I look. I'm posting information about these tests as other's have posted such.

Greenpower posted several tests and because of what I learned from his posts I've done the REPEAT DIAGNOSTICS test because his posts made it look like it is legitimate and provided a lot of data.

Kevnsworld asked for an opinion about Spectracell, and I responded with my experience.

That's how this train of thought got started - me responding to his question.

You're just looking for ways to be abusive.

Please don't post about my posts, as you consistently twist statements, go beyond what is said and get personal.

[smithx]

This is off topic nonsense and I request that it be taken out of this C60 thread.

[mikey]

This is off topic nonsense and I request that it be taken out of this C60 thread.

It is quite on topic as it is getting third party measurements to compare to the same third-party measurements after having taken C60oo consistently for some time period.

I will re-take the same tests - if they seem valid - a year after taking a consistent amount of C60oo in the interest if seeing what lab tests show.

Anecedotes have value but lab tests have much more value.

So far, Spectracell and Lifelength tests seem suspect. I've just had he REPEAT DIAGNOSTICS tests that Greenpower had to see what they say, as their tests seemed much more credible as well as being more detailed.

Third party testing is an important variable as we look at what is happening because of C60oo use.

I certainly am willing to spend the money to get third party evaluation as to what is happening in my metabolism and share it on LongeCity.

This is off topic nonsense and I request that it be taken out of this C60 thread.

It is quite on topic as it is getting third party measurements to compare to the same third-party measurements after having taken C60oo consistently for some time period.

I will re-take the same tests - if they seem valid - a year after taking a consistent amount of C60oo in the interest if seeing what lab tests show.

Anecedotes have value but lab tests have much more value.

So far, Spectracell and Lifelength tests seem suspect. I've just had he REPEAT DIAGNOSTICS tests that Greenpower had to see what they say, as their tests seemed much more credible as well as being more detailed.

Third party testing is an important variable as we look at what is happening because of C60oo use.

I certainly am willing to spend the money to get third party evaluation as to what is happening in my metabolism and share it on LongeCity.

[Kevnzworld]

I think the telomere testing would be relevant if there was a before and after test from the same lab. It would be interesting to see if C60 had any effect on telomere length. Unfortunately, after more than 6 months of use that would be difficult to determine in Mikey's case.

[pleb]

it would have to be done in isolation, with the person being tested not taking any other supplement that could effect Telomere length,

i've read that 80% of damage suffered by the telomeres over their life is caused by ROS,
is it known if the damage effects how quickly they shorten ?

even if most of the ROS is eliminated by C60 it wouldn't necceceraly translate into telomers shortening at a slower rate,
as its normal for them to shorten they may just continue shortening at the same rate but just be in a healthier condition,


reading the posts on here makes me wonder why so many posters expect the various suppliments to make them younger !!!

the majority of the things we take may extend lifespan but where all these ideas poster have about also making them younger leaves me baffled,

Edited by pleb, 13 December 2012 - 10:36 AM.

[niner]

it would have to be done in isolation, with the person being tested not taking any other supplement that could effect Telomere length,

i've read that 80% of damage suffered by the telomeres over their life is caused by ROS,
is it known if the damage effects how quickly they shorten ?

even if most of the ROS is eliminated by C60 it wouldn't necceceraly translate into telomers shortening at a slower rate,
as its normal for them to shorten they may just continue shortening at the same rate but just be in a healthier condition,

The evidence in humans, looking at people in high-stress situations, for example, suggests that under such conditions (presumably characterized by higher redox stress) the telomeres are actually shorter. I'm not sure what the mechanism of this would be, but it's known that DNA repair doesn't work as well on telomeres as it does on genomic DNA.

reading the posts on here makes me wonder why so many posters expect the various suppliments to make them younger !!!

the majority of the things we take may extend lifespan but where all these ideas poster have about also making them younger leaves me baffled,

It depends on how you define "younger". Obviously, we don't have a "time machine in a bottle", but there are lots of things that give people more youthful characteristics. Plenty of people here, myself included, have seen shifts toward more youthful states in appearance, stamina or strength from a variety of interventions. It looks like astragalus compounds are able to actually lengthen the telomeres of at least some cells, which is pretty much the definition of "turning back the (biological) clock". There are still a lot of types of aging damage, like extracellular glycation, that we don't have good fixes for, at least yet, but we keep plugging away at it, and will get there eventually.

[pleb]

Hi Niner i do understand what your saying, i have also felt a lot fitter (younger) since starting on both C60,
and Eptalon, which according to the Russian literature lengthens telomeres,

so yes it would depend on each persons definition of younger, I'm also pretty sure that if i sent my cells to be tested the result would come back that i'm still a 67 year old fart, irespective of telomere length
whereas some seem to expect the results to show they are back to a much younger age at the cellular level unless i am misinterpreting their posts and/or what they are expecting the tests to show,,

Edited by pleb, 13 December 2012 - 02:44 PM.

[Turnbuckle]

whereas some seem to expect the results to show they are back to a much younger age at the cellular level unless i am misinterpreting their posts and/or what they are expecting the tests to show,,

Some here are seeing certain signs of age-reversal due to C60, but this would be from improvement of mitochondrial functioning (and perhaps activation of stem cells for the same reason). The telomeres of most cells are unlikely to be affected, however, so these tests won't reflect how they feel.

Edited by Turnbuckle, 13 December 2012 - 02:53 PM.

[Kevnzworld]

i
reading the posts on here makes me wonder why so many posters expect the various suppliments to make them younger !!!

the majority of the things we take may extend lifespan but where all these ideas poster have about also making them younger leaves me baffled,

I think that significant life extension from the current science is unlikely. The NIH rhesus monkey CR failure , the disappointing studies on resveratrol are recent examples. I do believe we are squaring the curve, and longer healthier lifespans will result. There have been advances in mitigating though not reversing glycation. Something as simple as green coffee been extract has been effective at lowering my postprandial blood sugar significantly. My HbA1C continues to decline. Hopefully , carnosine , taurine, benfotiamine and P5P are limiting the damage from glucose. ( helping us " look" younger than we otherwise would have ).
C60 is a wild card. Yes, it was only 6 rats ( as mind reminds us ),..but the underlying science is hopeful. I continue with my 1.6mg intermittent dosing waiting for new and better science.

[pleb]

Thanks guys for your input, i can appreciate the thinking that many have in their semantics regarding the term younger,

i agree about the wild card, (C60)

what i have to try and do now is cut my sugar intake down, 7 to 10 brews of tea a day with 3 heaped teaspoons in each can't be doing me any good at all,

i have had blood tests done within the last week and all were normal including blood sugar and chloresterol, but at my age i think perhaps i have just been lucky which won't hold for ever,

Edited by pleb, 13 December 2012 - 05:14 PM.

[Johnny B]

Hi Niner i do understand what your saying, i have also felt a lot fitter (younger) since starting on both C60,
and Eptalon, which according to the Russian literature lengthens telomeres,

I couldn't find Eptalon. Do you have a link?

Does anyone have any reliable info on lengthening telomeres and which supplements work the best?

[pleb]

Hi it's in supplements, under, Epitalon (split from Astragalus thread) i'll try and post the Russian test (in English) later, it's also spelt Epithalon,
i had spelt it wrong in the previous post so apologies for that,

Edited by pleb, 14 December 2012 - 08:42 AM.

[pleb]

http://www.innovitar...s/10062201.html


Ala-Glu-Asp-Gly Peptide Induces Telomere Elongation in Human Fetal Cell Culture Posted on: June 22, 2010
It was shown that treatment of normal human diploid cells with Epithalon (Ala-Glu-Asp-Gly) induced expression of telomerase catalytic subunit, its enzymatic activity, and elongation of telomeres. So scientists studied the effect of this peptide on proliferative potential of human fetal fibroblasts.
Primary pulmonary fibroblasts derived from a 24-week fetus lost the proliferative potential at the 34^th passage. The mean size of telomeres in these cells was appreciably lower than during early passages (passage 10).
Addition of Epithalon to aging cells in culture induced elongation of telomeres to the size comparable to their length during early passages. Peptide-treated cells with elongated telomeres made 10 extra divisions (44 passages) in comparison with the control and continued dividing.
Hence, Epithalon prolonged the vital cycle of normal human cells due to overcoming the Heyflick limit. Source: Khavinson VKh, Bondarev IE, Butyugov AA, Smirnova TD.; Peptide promotes overcoming of the division limit in human somatic cell.; Bull Exp Biol Med. 2004 May;137(5):503-6.

[tintinet]

Cells in culture, perhaps. But I still think it's exceedingly unlikely taking epithalon will beat a placebo over the course of a human life span. Still, I'm taking it. It seems to promote vivid dreams, FWIW.

[niner]

Cells in culture, perhaps. But I still think it's exceedingly unlikely taking epithalon will beat a placebo over the course of a human life span. Still, I'm taking it. It seems to promote vivid dreams, FWIW.

Seems like you should invest in something with better odds, then. But here's a question: Is there any experimental evidence in higher animals (vertebrates, at least, if not mammals) that epithalon does anything useful? I guess there's Hugo, but I'm looking for something in the peer reviewed literature.

[Kevnzworld]

Cells in culture, perhaps. But I still think it's exceedingly unlikely taking epithalon will beat a placebo over the course of a human life span. Still, I'm taking it. It seems to promote vivid dreams, FWIW.

Seems like you should invest in something with better odds, then. But here's a question: Is there any experimental evidence in higher animals (vertebrates, at least, if not mammals) that epithalon does anything useful? I guess there's Hugo, but I'm looking for something in the peer reviewed literature.

Epitalon promotes pineal gland secretion of melatonin, which can explain the vivid dreams and some of its reported benefits. Most of the studies have been conducted by Khavinson , whose institution holds its patent. I take melatonin, but not Epitalon.
Here is a review of the research that I found interesting. Human studies begin on page 289.

http://books.google....smutase&f=false

[pleb]

Cells in culture, perhaps. But I still think it's exceedingly unlikely taking epithalon will beat a placebo over the course of a human life span. Still, I'm taking it. It seems to promote vivid dreams, FWIW.

you may be correct,

the first line indicates this test was on the 24 week fetus cells,

but the first sentence after that indicate the tests were done because they had already noted the Telomere elongation results presumably from previous tests,
unfortunately finding the Russian literature about the previous tests would probably be difficult,

also due to the system in the ex soviet union peer reviews were not done the same as they are in the west, the higher you were in the system the less chance of any questions,from other researchers especially those on a lower rung of the ladder, the whole is built on a hierarchical system

Edited by pleb, 15 December 2012 - 04:49 PM.