3585 replies to this topic

[hav]

Not THE link, but here are some links

http://www.ncbi.nlm....pubmed/21071824

www.electrochem.org/dl/ma/201/pdfs/1004.pdf

http://www.scienceda...70417154357.htm

I need sleep and tomorrow I will see if I can dig it back out of the internet.

Yeah, not the same as injecting cancer. But it seems likely that if C60 does stimulate mitochondrial function, that will eliminate the Warburg effect (cancer cells shutting down mitochondria and resorting to glycolysis) and either normalize the cell or induce apoptosis (which requires functioning mitochondria).

Was curious what form of c60 they used and stumbled across the free full-text here:

https://www.landesbi...hangAUTO5-8.pdf

Looks like it was a water soluble fullerene in vitro:

Nano-C60 preparation. We prepared water-dispersed Nano-C60 according to the modified tetrahydrofuran procedure as described.34...
34. Fortner JD, Lyon DY, Sayes CM, Boyd AM, Falkner JC, Hotze EM, et al. C60 in water: nanocrystal formation and microbial response. Environ Sci Technol 2005; 39:4307-16.

They mention its general toxicity to normal cells later in the paper:

Given the considerable toxicity of fullerenes, and particularly Nano-C60,29 towards normal cells, it would be highly desirable to explore whether the ability of fullerenes to induce autophagy at low and noncytotoxic concentrations could be exploited to improve cancer chemotherapy.

I think that might be the same flawed c60 formulation that was later determined to have killed fish with due to tetrahydrofuran impurities.

Howard

[TRUGAN]

When do you guys think human studies will be done to prove c60 doesn't damage dna and cause cancer or something else?
I see a lot of articles speaking of nano materials damaging dna,

Just got my magnetic stirrer in the mail today.

[niner]

When do you guys think human studies will be done to prove c60 doesn't damage dna and cause cancer or something else?
I see a lot of articles speaking of nano materials damaging dna,

Just got my magnetic stirrer in the mail today.

Don't hold your breath... Serious human studies are a long way off, although there have probably been ten thousand people who have used it. The thing about all those papers that talk of nano materials is that they are dealing with different molecules. C60-oo is a single molecule, and a lot of the dangerous materials are aggregates containing very large numbers of molecules. When the molecules are different, the properties are different. The existing animal data says c60 is harmless, at least if you're a rat. Since I'm not any (believable) reports of serious problems among the large numbers of human users, I take this to mean that there aren't any serious short-to-moderate term toxicities. If there are long term human toxicities, I guess time will tell...

[TRUGAN]

I think I jumped into this too fast. My 30 ml arrived today and so far Ive just stared at it.

I read some where earlier the same comment you made about it being ok if you're a rat. lol...I guess being a big ass rat is not the same.

I got to decide whether to waste this bottle or try it.

I'd just hate to take it now and then get cancer from dna damage 20 years later when I'm 65 or even sooner for all we know.

I will probably take this bottle and just hope one bottle doesn't jack me up and then think more about long term use depending on whether it does anything for me.

Has anyone considered having tests to see if any kind of damage has been done? I dont know what tests could even be done other than biopsies.

I dont imagine too many people want to do that.

[resting]

Risk reward is all part of life. If I were in my 20's / 30's I would be waiting for more data. If you are in your 50's+ then the decision is not as hard to make.

[TRUGAN]

It might not be much worse than all the crap Ive already been exposed to. Maybe it will fix some of it.

[TRUGAN]

Any objections to this oil?

http://amphoranueva....?p=product&id=2

[free10]

So do you think that if the C60oo is made with olive oil that has some rancidity that the C60 could present toxicity?

I think that is very likely. And if allowed to age at room temperature or exposed to UV, it will eventually get used up and become a pro-oxidant.

Sounds like it's best to keep it in a refrigerator then.

Keeping it in the fridge gets you a 4-fold extension rather than a 16-fold in the freezer. And in the fridge, you will get separation when the waxy material freezes and the rest doesn't. In the freezer, everything freezes and it stays homogeneous.

One more point was they took rats and injected them with cancers and those on C60 lived 2 to 3 times the days before they died. It seems to interfere with its ability to spread.

That's new to me. Do you have a link?

The lost link, so far, but I know I saw it. One of the things that makes me remember it so well was a graph showing the days for each, and noticing how few days for them to die without protection from the injected cancer.

I did come up with some other links though

http://www.exp-oncol...pubmed/21956470

http://www.ncbi.nlm....pubmed/19786831

http://www.electroch...1/pdfs/1004.pdf

http://link.springer...2645-011-0020-x

http://exp-oncology....ua/article/1776

http://iopscience.io...1_415102.pdf..

C 60 is a fullerene, identified in the early 1990s, with
unique globular structure consisting of 32 different
member rings and containing a total of 60 carbon atoms.
Fullerene C 60 possesses potent anti-cancer activities and induces certain markers of autophagy in cancer cells (75). It has significant toxicity to normal tissues, which limits its use as therapeutic (76). Nanocrystals of underivatized fullerene C 60 (Nano-C 60 ) have been used in concentrations that are non-toxic to normal cells to study their effects on radiosensitization. B16 and SMMU-7721 cell lines were tested with Nano-C 60 and γ-radiation and were found to show enhanced membrane damage and induced apoptotic
cell death (77). Nano-C 60 has also been shown to possess chemosensitizing activity and hence can serve as a potential adjuvant therapeutic in cancer (75).

http://www.thetcr.or...wnload/1550/pdf

[TRUGAN]

I was reading from the link below that too many antioxidants could be bad. Do you guys think this is why some dont do well when they take too much C60?

http://www.huffingto..._b_1449974.html

Also, is there a place where a lot of people are recording the positive benefits they have received? Ive had a hard time finding reviews on the net but supposedly thousands are taking it.

Just trying to get as much info as I can while I brew my batch. I'm thinking of giving this to my elderly mother and my 10 year old cat thats had asthma all her life.

[ambivalent]

loosely on topic: not buckyballs rather sticky-balls

http://www.bbc.co.uk...health-25625934

cancer; nanotechnology

Edited by ambivalent, 07 January 2014 - 03:38 PM.

[Logan]

I was reading from the link below that too many antioxidants could be bad. Do you guys think this is why some dont do well when they take too much C60?

http://www.huffingto..._b_1449974.html

Also, is there a place where a lot of people are recording the positive benefits they have received? Ive had a hard time finding reviews on the net but supposedly thousands are taking it.

Just trying to get as much info as I can while I brew my batch. I'm thinking of giving this to my elderly mother and my 10 year old cat thats had asthma all her life.

Just take it. Take half the dose recommended. It probably won't ever hurt you. I plan on taking Depakote(valproic acid) till I die, and I can almost guarantee I will not develop a single disease as a result. Heck, I might actually live longer.

You have to take risks in life, if you really want to increase chances of surviving the way you desire. There is absolutely no reason to believe a low dose of C60 4-5 days a week will harm you in any way whatsoever. Stop deliberating and just take the shit dude.

Edited by Logan, 18 January 2014 - 07:11 AM.

[YOLF]

Anyone with such a gung-ho attitude should definitely be signed up and payed up for cryonics just in case. I'm not arguing that those are bad for you, just saying you should always put safety first when using supplements.

[TRUGAN]

Just giving it to my cat at the moment. I'm giving her 2ml once a weak and she had second dose yesterday. She is 12 years old so I'm hoping maybe it will extend a life a little although she is healthy except for Asthma. So far she tolerates it well with no noticeable effects but no improvements in Asthma either.

[Izan]

can anyone explain to me why c60 has the same effect on me as taking anavar, 100 mg/day, but without the side effects? after three weeks of c60, my body is shredded to the max and the increase in my physical strength is just ridiculous. i'm 32 years old, 186 cm tall and i weigh 81 kgs. thanks.

[TRUGAN]

how much c60 do you take?

[YOLF]

IMLO, Many athletes have posted about having huge athletic gains while on C60, some are even winning awards that were previously out of their reach. If a rat in a cage can live twice it's regular lifespan from having 24 doses in it's late youth, it must be thriving quite well. Muscle growth must happen when we thrive. But as it is thought to work through mitochondrial autophagy, it may just be ensuring that only your best mitos are producing energy and freeing you from the pollution of aging. Other cells running entirely on bad mitos may even die off leaving you with only the strongest of your cells and may result in higher potential for proliferation of good cells.

[clairvoyant]

can anyone explain to me why c60 has the same effect on me as taking anavar, 100 mg/day, but without the side effects? after three weeks of c60, my body is shredded to the max and the increase in my physical strength is just ridiculous. i'm 32 years old, 186 cm tall and i weigh 81 kgs. thanks.

You should have said that Anavar is an anabolic steroid. As for C60, the improved fat tissue burning comes from enhanced mitochondrial function. I experienced the same. About strength, it is more ATF produce. By the way Anavar is a mild steroid, so, it should not have had side effects.

Edited by clairvoyant, 20 January 2014 - 06:42 PM.

[VP.]

can anyone explain to me why c60 has the same effect on me as taking anavar, 100 mg/day, but without the side effects? after three weeks of c60, my body is shredded to the max and the increase in my physical strength is just ridiculous. i'm 32 years old, 186 cm tall and i weigh 81 kgs. thanks.

More details please. Are you associated with Boris Sala? Thanks.

[Watdh]

I was reading from the link below that too many antioxidants could be bad. Do you guys think this is why some dont do well when they take too much C60?

http://www.huffingto..._b_1449974.html

Also, is there a place where a lot of people are recording the positive benefits they have received? Ive had a hard time finding reviews on the net but supposedly thousands are taking it.

Just trying to get as much info as I can while I brew my batch. I'm thinking of giving this to my elderly mother and my 10 year old cat thats had asthma all her life.

Just take it. Take half the dose recommended. It probably won't ever hurt you. I plan on taking Depakote(valproic acid) till I die, and I can almost guarantee I will not develop a single disease as a result. Heck, I might actually live longer.

You have to take risks in life, if you really want to increase chances of surviving the way you desire. There is absolutely no reason to believe a low dose of C60 4-5 days a week will harm you in any way whatsoever. Stop deliberating and just take the shit dude.

WTH??? Depakote almost killed me- or I thought it was killing me. Side effects of hair falling out and growing back like something more like straw and all the weight gain- it really kicked in the depression.

[Izan]

can anyone explain to me why c60 has the same effect on me as taking anavar, 100 mg/day, but without the side effects? after three weeks of c60, my body is shredded to the max and the increase in my physical strength is just ridiculous. i'm 32 years old, 186 cm tall and i weigh 81 kgs. thanks.

You should have said that Anavar is an anabolic steroid. As for C60, the improved fat tissue burning comes from enhanced mitochondrial function. I experienced the same. About strength, it is more ATF produce. By the way Anavar is a mild steroid, so, it should not have had side effects.

thanks for the explanation. but anavar can give you negative side effects, shutdown of test production + lethargy are the biggest side effects which i've experienced. i have a new bottle of c60 coming my way, so let's see if i'll still be able to get these wonderfull effects from c60.

[ambivalent]

I ordered my supply of c60oo last July; I planned on low doses so I purchased some small 10ml plastic dropper bottles and transferred the c60oo to them and proceded to freeze them. I recall there being concerns over contaimination with plastic - is this risk significantly mittigated given it is frozen? I have just started re-trialing c60 and will consider ordering another batch and perhaps freeze with small glass bottles. Thanks in advance.

[niner]

I ordered my supply of c60oo last July; I planned on low doses so I purchased some small 10ml plastic dropper bottles and transferred the c60oo to them and proceded to freeze them. I recall there being concerns over contaimination with plastic - is this risk significantly mittigated given it is frozen? I have just started re-trialing c60 and will consider ordering another batch and perhaps freeze with small glass bottles. Thanks in advance.

It's probably ok. It depends on the type of plastic. Does it have a recycling number on it? It should help that it's frozen.

[TRUGAN]

what does the recycle number mean?

[ambivalent]

Thanks for the response niner: the only writing I can see is on the base - "BXL 1862/12"

I appear to have bought them from ampulla.co.uk; though I can't see the original product there. They seem to differ only in size with the following:

http://www.amazon.co... Dropper Bottle

It might be prudent to re-order c60oo; I probably have a year's supply or more, I've not settled on a dose yet.

Edited by ambivalent, 05 February 2014 - 11:15 PM.

[niner]

Plastic Recycling Code Numbers

As far as health hazards go, 1,2,4, and 5 are relatively safe; 3,6, and 7 are not. 7 is a catch-all category that includes some ok plastics and some dangerous ones.

[TRUGAN]

Thanks, thats good info to know.

[niner]

Thanks for the response niner: the only writing I can see is on the base - "BXL 1862/12"

I appear to have bought them from ampulla.co.uk; though I can't see the original product there. They seem to differ only in size with the following:

http://www.amazon.co... Dropper Bottle

It might be prudent to re-order c60oo; I probably have a year's supply or more, I've not settled on a dose yet.

Those are LDPE (Low Density Polyethylene). They're considered to be safe.

[ambivalent]

ok, that's great. Thanks very much.

[ambivalent]

I have above average number of moles, which naturally does create risk, but also I learned a couple of years ago is associated with delayed aging.

http://www.bbc.co.uk...health-11813378

Anyhow, within the last couple of days I noticed a mole by my ear to be more pronounced than usual and today I've nicked it shaving (which might be a very intermittent occurrence) and of course it has bled profusely. I believe also I nicked another a week or so ago. Whilst this can happen, shaving, I feel rather supports the feeling that that mole and perhaps another had become more pronounced. I certainly can't be sure of this, it isn't a cast iron observation; however, I raise it because I started taking c60 about 3 weeks ago for the first time in 6 months. I wonder has anyone has had any comparable observation or thoughts on this?

Thanks in advance.

Edited by ambivalent, 13 February 2014 - 10:02 PM.

[SearchingForAnswers]

My wife and I have just started c60OO last week.
She went for a run and said it was fantastic (about 2 hrs after taking). However, She hasn't noticed much since. We ordered the bucklylabs brand, will likely mix our own or try another next time.
However She doesn't feel much different lately, although She has had few headaches.

My experience is different, but I had a good experience in the gym on the treadmill & lifting like Her.
Other things I take:
Paxil CR
SAM-E (Really helps the Paxil work)
A variety of other supplements, milk thistle, curcumin, etc...

However, I had to stop taking the SAM - e. It seems to have gone from helping me to making me feel bi - polar; up and down, but mostly down. I realize this has something to do with meythlation - could the c60OO perhaps have turned me from an under - methlyater to an over - methylater? Or is it simply too early to really tell much, given it's only been a week?

I'm 225 lbs, probably about 20 overweight, and initially took 15 droppers full (one squeeze of the bulb) and was taking 1.5 droppers daily. Think I'm going to just once a week dosing, however.

My wife initially took 10 droppers, and is now taking one daily.