1725 replies to this topic

[He@dshot]

will this be the first group buy on longecity?

[Major Legend]

I've started a discussion with management.



I think there is merit, but there are a number of issues to be considered, including risk management, legal liabilities and the potential for proper trial parameters to be established. It's possible that if they do agree to facilitate this, that it'll be a members-only process, but I'm only guessing.
I'll/they'll jump in here with updates, as things progress.

If the board does agree to help get this rolling than i have a few suggestions. First a supplier needs to be chosen along with the amount of PRL-8-53. This will give us the cost of of synthesizing PRL-8-53.

I erred earlier in the thread about 10g for $1300 from HM-Chemo. But i recontacted HM-Chemo and this is what i got, 10g for $1200 or 100g for $3000. I confused the 100g for $1300 with the company I cannot for the life of me find that was a US based sourcing company. I found it when the PRL-8-147 thread was started, i can remember pretty much everything about the page except the name/address.

Lets say Longecity decides to help with this project and the 10grams for $1200 is chosen, just as an example. There has been no decision on a supplier or final amount yet. Longecity sets up a donations slot that anyone can donate to. Even those who have no desire to participate in the trial. The cost of (still an example) 10g would be $1500 after shipping and repacking but the donation slot would be set between $2000-3000 so there is a lot of wiggle room and room for the community to profit. From their Longecity could make forms for persons wanting to be participants. The forms would be agreements (if accepted) that would likely entail things concerning legal liabilities, proper trial parameters, keeping logs, safety procedures and so on. This allows Longecity control over the testing so it can be treated more like a proper trial.

If 10 grams is selected than I would suggest that 250mg or 500mg samples be the sample amount sent out to testers. This allows for 40 participants 50 doses at 5mg for the 250mg sample or 20 participants 100 doses at 5mg for the 500mg sample.

This is all just an idea and we will have to wait and see if Longecity wants to do.

I find Longecity option the best seeing that it allows the community to profit.



Another option would be to have someone working with a company to make the order and handle the money.

Mod here, can someone give me a quick rundown on what you're wanting us to facilitate? Monetary stuff will have to go beyond us to board/secretary level discussion, but I'm considering jumping into this group-buy and own a company, so there may be other things that can be done.

How do we get this going, and how long should we wait before we take it into our own hands?

[MrHappy]

From Management:

The compound in question is not licensed to be sold for personal consumption, which is what LongeCity would be doing if it facilitated payments or gave assurances regarding the repackaging and distribution.

LongeCity isn't a licensed medical company, so it is unable to legally facilitate the request and it would be liable for any risk/harm to members.

Sorry people, it will need to be done as private/personal transactions.

[megatron]

Who wants to collect the money and place the order then? We need someone trusted.

[Reformed-Redan]

From Management:

The compound in question is not licensed to be sold for personal consumption, which is what LongeCity would be doing if it facilitated payments or gave assurances regarding the repackaging and distribution.

LongeCity isn't a licensed medical company, so it is unable to legally facilitate the request and it would be liable for any risk/harm to members.

Sorry people, it will need to be done as private/personal transactions.

Yeah, Longecity would have to source this compound as a research chemical; but, that would be sketchy and we don't want to turn this forum into some bluelight forum.

Who wants to collect the money and place the order then? We need someone trusted.

Q did it!, must be busy. We'll find out what quotes he got from other supplers. But, looks like the safest bet would be Novochemy @ $500 for 10 g. I'd be willing to get 500mg so more people can obtain this compound. That's still 100 days worth of doses. More than enough time to asses this compound.

Actually I can go as low as 250mg, just for an initial trial. That should satisfy everyone's needs.

[Reformed-Redan]

This is pretty interesting. I've been looking at Novochemy and Arkpharma. Both had a supply of this compound in about >5. Since the start of this thread all are backordered. Wonder who bought it all up.

[Q did it!]

Just want to let you guys know what i am just waiting for on more quote to come in than i will let kown what the virdict is regarding the order amount, number of slots and cost. And yes I have been very busy the these last few days, this post was sent from my phone.

[Reformed-Redan]

If we can't find someone who has a business associate or a company to order this compound safely we'll have to source it from China. No other way around it. Anyone found/know of any trustworthy suppliers. T&W gave a quote of $3000 for a Kilo. Right? T&W are the same manufacturers of Sunifiram and Unifiram. Let me get some more feedback apart from me and Q did it for this to happen.

[Animal]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

[Reformed-Redan]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

Yeah. But, I don't want to have enchanced memory all day and night. That would be like being stimulated 24 hrs. It's a promising compound. Wish I could get feedback from the ppl that backordered Novochem and arkpharma. lol

[Q did it!]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

Yeah. But, I don't want to have enhanced memory all day and night. That would be like being stimulated 24 hrs. It's a promising compound. Wish I could get feedback from the ppl that backordered Novochem and arkpharma. lol

ArkPharm was on the back order list when I found it NovoChemy was to they just had not updated it yet.

T&W
$2900 for 10grams
http://www.hm-chemo....ail/51352-87-5.
10g $1200
100g $3000
http://www.anward.co...o_result/55340/
USD

998/5g

http://www.tractusch...om/aboutus.html
1g for $826
http://arkpharminc.c...AK-55207&falg=3
.25g $112
1g $280
http://www.novochemy...spx?pr_id=13581
10g $400
http://www.bocsci.com/
10g $2000
http://fartop.net/
2980/10G
http://www.angeneche...AG-F-73692.html
http://www.ispharm.c.../I01-32330.html
http://www.huichem.com/cas/51352-87-5
http://www.acersci.c...o_result/55340/
http://www.jnhaohua....imageField.y=15
http://www.haihangch...uct/product.asp
http://www.letopharm...ogNo=LT0312304#
http://www.raise-che...alogNo=RS093026

And i found the company I could not for the life of me find. I am still awaiting their reply.

[HenryHH]

Definitely keep us updated -- I can't wait to get my hands on this and hope that an arrangement can be worked out with a manufacturer.

[Q did it!]

My choice right know for the supplier is NoveChemy 10g for 400USD but I wont be decided until a reply from the company that I eagerly await is received. Once supplier and costs are known we can move foreword with the group buy. It should only be a day or two more tell we know.

[Mr. Pink]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

Yeah. But, I don't want to have enchanced memory all day and night. That would be like being stimulated 24 hrs. It's a promising compound. Wish I could get feedback from the ppl that backordered Novochem and arkpharma. lol

i think you may be overestimating the positive effect on memory you're liable to get. i could be wrong though (hope so actually).

but this reminded of women who don't want to lift weights because they're afraid they'll get big muscles. yes weightlifting is scientifically proven to cause muscle gains (much more so proven than any nootropic, especially this one), yet even most males, who have a ridiculously higher amount of testosterone than women don't really get big. only the genetically gifted + lots of steroids.

anyway, just saying i wouldn't worry about having a memory that's TOO good.

[Q did it!]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

Yeah. But, I don't want to have enchanced memory all day and night. That would be like being stimulated 24 hrs. It's a promising compound. Wish I could get feedback from the ppl that backordered Novochem and arkpharma. lol

i think you may be overestimating the positive effect on memory you're liable to get. i could be wrong though (hope so actually).

but this reminded of women who don't want to lift weights because they're afraid they'll get big muscles. yes weightlifting is scientifically proven to cause muscle gains (much more so proven than any nootropic, especially this one), yet even most males, who have a ridiculously higher amount of testosterone than women don't really get big. only the genetically gifted + lots of steroids.

anyway, just saying i wouldn't worry about having a memory that's TOO good.

It probably (hopefully this drug works) is one of those things that work best if you were already smart to start with. lol

[Reformed-Redan]

From what limited information is available it would appear that this compound would need to be dosed multiple times per day in order for the effects to be maintained. I think you are being naive if you expect to get sustained cognitive enhancement from 5mg/day.

I'm interested in the results of this endeavor, but I won't be participating, at least not at this early stage. I personally find all cholinergic substances to have a deleterious effect on my mood; one reason PRL-8-53 intrigues me is because if it is a positive allosteric modulator of acetylcholine receptors, it may avoid this negative effect entirely.

I have my own ideas on where the future of intellectual enhancement lies, and am professionally working towards that end. In the interim, I think neurochemical modulators like this are an engaging diversion.

Yeah. But, I don't want to have enhanced memory all day and night. That would be like being stimulated 24 hrs. It's a promising compound. Wish I could get feedback from the ppl that backordered Novochem and arkpharma. lol

ArkPharm was on the back order list when I found it NovoChemy was to they just had not updated it yet.

T&W
$2900 for 10grams
http://www.hm-chemo....ail/51352-87-5.
10g $1200
100g $3000
http://www.anward.co...o_result/55340/
USD

998/5g

http://www.tractusch...om/aboutus.html
1g for $826
http://arkpharminc.c...AK-55207&falg=3
.25g $112
1g $280
http://www.novochemy...spx?pr_id=13581
10g $400
http://www.bocsci.com/
10g $2000
http://fartop.net/
2980/10G
http://www.angeneche...AG-F-73692.html
http://www.ispharm.c.../I01-32330.html
http://www.huichem.com/cas/51352-87-5
http://www.acersci.c...o_result/55340/
http://www.jnhaohua....imageField.y=15
http://www.haihangch...uct/product.asp
http://www.letopharm...ogNo=LT0312304#
http://www.raise-che...alogNo=RS093026

And i found the company I could not for the life of me find. I am still awaiting their reply.

Awesome Q. Given the amount of interest, we could ask Novochemy for a bulk order for a good price. I think it's dooable. :D

[hadora]

this experiment is gonna fail :/

[Major Legend]

this experiment is gonna fail :/

Why do you say that? Too bad I can't be the receiver since I am all the way in Hong Kong.

[Logic]

This is pretty interesting. I've been looking at Novochemy and Arkpharma. Both had a supply of this compound in about >5. Since the start of this thread all are backordered. Wonder who bought it all up.

Interesting and disturbing: If this compound is as 'unknown' as everybody thinks; why would someone go to so much trouble and expense to keep people here from trying it..?

[Adam90]

This is pretty interesting. I've been looking at Novochemy and Arkpharma. Both had a supply of this compound in about >5. Since the start of this thread all are backordered. Wonder who bought it all up.

Interesting and disturbing: If this compound is as 'unknown' as everybody thinks; why would someone go to so much trouble and expense to keep people here from trying it..?

The Illuminati

[hadora]

this experiment is gonna fail :/

Why do you say that? Too bad I can't be the receiver since I am all the way in Hong Kong.

1) this compound probably doesn't work and it's probably the reason why it was dropped
2) this compound doesn't have much research behind it so the side effects are unknown
3) it work only for a few hours then you need to redose it, that mean increased chance of side effects and since side effects are unknown you can't use it long term
4) alot of other reasons

This is pretty interesting. I've been looking at Novochemy and Arkpharma. Both had a supply of this compound in about >5. Since the start of this thread all are backordered. Wonder who bought it all up.

Interesting and disturbing: If this compound is as 'unknown' as everybody thinks; why would someone go to so much trouble and expense to keep people here from trying it..?

www.abovetopsecret.com

[He@dshot]

didn't someone here said that it was probably dropped because of no patent -> no possible revenue ?

Edited by He@dshot, 26 March 2013 - 02:55 PM.

[mait]

But the Chinese company T&W seems reputable - why not take this route???

[Reformed-Redan]

this experiment is gonna fail :/

Why do you say that? Too bad I can't be the receiver since I am all the way in Hong Kong.

1) this compound probably doesn't work and it's probably the reason why it was dropped
2) this compound doesn't have much research behind it so the side effects are unknown
3) it work only for a few hours then you need to redose it, that mean increased chance of side effects and since side effects are unknown you can't use it long term
4) alot of other reasons

Mehh. I think 1 can be answered by directing you the the human studies that have been referenced like 10x on this thread.

[hadora]

this experiment is gonna fail :/

Why do you say that? Too bad I can't be the receiver since I am all the way in Hong Kong.

1) this compound probably doesn't work and it's probably the reason why it was dropped
2) this compound doesn't have much research behind it so the side effects are unknown
3) it work only for a few hours then you need to redose it, that mean increased chance of side effects and since side effects are unknown you can't use it long term
4) alot of other reasons

Mehh. I think 1 can be answered by directing you the the human studies that have been referenced like 10x on this thread.

as far as i'm aware there is only one human study about it, i don't think it enough anyway
can someone explain me why this compound have 2 slightly different structures ?

i found this


and this


does this difference matter ?

[Q did it!]

this experiment is gonna fail :/

Why do you say that? Too bad I can't be the receiver since I am all the way in Hong Kong.

1) this compound probably doesn't work and it's probably the reason why it was dropped
2) this compound doesn't have much research behind it so the side effects are unknown
3) it work only for a few hours then you need to redose it, that mean increased chance of side effects and since side effects are unknown you can't use it long term
4) alot of other reasons

Mehh. I think 1 can be answered by directing you the the human studies that have been referenced like 10x on this thread.

as far as i'm aware there is only one human study about it, i don't think it enough anyway
can someone explain me why this compound have 2 slightly different structures ?

i found this


and this


does this difference matter ?

It is the same molecule viewed from two opposing sides. If you were to flip the first image it would line up with the second.

[hadora]

edit: you're right, didn't paid attention lol

Edited by hadora, 26 March 2013 - 05:38 PM.

[Thor]

I want to join too

[Reformed-Redan]

Well be starting a new thread soon (by Friday) with all payment details, the amount to be offered for everyone, and the nitty gritty details. We'll keep you updated.

[hellbounddevildog]

Thanks for all the hard work in researching companies guys. Wish I could do more for the project at this point. I'm looking forward to giving it a go. I'll keep checking back.