1725 replies to this topic

[sparkk51]

I see the the supplier is having a hard time with suppliers delivering things on time. I'd like to request that the ISRIB be cancelled alongside the PRL synthesis. I'm sorry. The existing participants will still get ISRIB albeight from a different supplier. Thanks.

Why don't we just wait until the first week of January. That doesn't seem that far off.

The right course of action here is to wait until the absolute deadline, namely close of business on 7th JANUARY 2014, has been reached and not to act prematurely. This is the proper way to act and as such is what will be happening here.

If the lab fails to complete the synthesis by close of business on 7th JANUARY 2014, then the order will be cancelled and I will be refunding everyone's money and personally will take the hit for all of the PAYPAL FEES (even though I did not in fact start this GROUP BUY but took it over when asked to by the person who did).

I have previously found this lab to deliver orders as per the requirement in every single instance, and in that respect they have to date been 100% reliable. Therefore, they deserve to be given the chance to complete the order.

Even so, I should point out that if this particular lab fails to deliver by the absolute deadline I for one will not be personally nor recommending anyone else use them ever again for any custom synthesis; and I have already told them this.

YADAYADA - Regards the ISRIB Group Buy, since you are managing that particular Group Buy it is entirely up to you how you wish to proceed. Whatever action you choose, please kindly note that I will still be very happy to assist you by managing the shipping. All I will require is the ISRIB bulk quantity, the participant list (including names and mailing addresses where to mail the individual samples), and the total shipping costs (= $145).

Just out of curiosity, if the lab does not deliver on their deadline, will you still use the lab as your go-to for custom synthesis? I am not sure if you only mean you will not recommend them or whether you will cut all personal ties as well?

[ScienceGuy]

Just out of curiosity, if the lab does not deliver on their deadline, will you still use the lab as your go-to for custom synthesis? I am not sure if you only mean you will not recommend them or whether you will cut all personal ties as well?

To clarify:

Even so, I should point out that if this particular lab fails to deliver by the absolute deadline I for one will not be personally nor recommending anyone else use them ever again for any custom synthesis; and I have already told them this.

[mait]

This is second try in synthesis of PRL-8-53. The first lab failed and now this - it shows that the compound we are waiting for is a tricky beast to deliver. In my book this honest communication between SG and the lab synthesizing PLR-8-53 is a big plus because it would be very easy to just ship some "half-ready" or "poor-quality" product to users and call it a day. This shows professionalism on the part of SG recommended lab and makes me very curios about the quality of Chinese products sold by other manufactures.

[ScienceGuy]

This is second try in synthesis of PRL-8-53. The first lab failed and now this - it shows that the compound we are waiting for is a tricky beast to deliver. In my book this honest communication between SG and the lab synthesizing PLR-8-53 is a big plus because it would be very easy to just ship some "half-ready" or "poor-quality" product to users and call it a day. This shows professionalism on the part of SG recommended lab and makes me very curios about the quality of Chinese products sold by other manufactures.

You have pretty much hit the nail on the head; even so, please be reassured that I would personally never, ever allow some "half-ready" or "poor-quality" product to be shipped to users, even if they attempted to supply it to me.

The issue as I see it comes down to RELIABILITY and COMMUNICATION, which IMO are key in any long-standing business relationship... if poor COMMUNICATION and poor RELIABILITY ever occur it is time to call it a day and move on to another supplier / manufacturer. I am aware of some structural changes within the lab's business and it could be an unhappy coincidence that these have occurred at the very same time as these supply issues have transpired, or it could be no coincidence at all and in fact a direct consequence... who knows? Either way there are many people here who will be let down by this lab's failure to deliver on this product order... and that will not do. IMO they absolutely deserve to be given this final chance to deliver, but if they fail yet again, then that's it as far as I am concerned... They will have blown it and I won't be using them ever again. Contrarily, if they come through and do meet the deadline then I most certainly will. Plain and simple. Let's wait and see what happens...

Edited by ScienceGuy, 25 December 2013 - 11:01 AM.

[Major Legend]

I see the the supplier is having a hard time with suppliers delivering things on time. I'd like to request that the ISRIB be cancelled alongside the PRL synthesis. I'm sorry. The existing participants will still get ISRIB albeight from a different supplier. Thanks.

Why don't we just wait until the first week of January. That doesn't seem that far off.

The right course of action here is to wait until the absolute deadline, namely close of business on 7th JANUARY 2014, has been reached and not to act prematurely. This is the proper way to act and as such is what will be happening here.

If the lab fails to complete the synthesis by close of business on 7th JANUARY 2014, then the order will be cancelled and I will be refunding everyone's money and personally will take the hit for all of the PAYPAL FEES (even though I did not in fact start this GROUP BUY but took it over when asked to by the person who did).

I have previously found this lab to deliver orders as per the requirement in every single instance, and in that respect they have to date been 100% reliable. Therefore, they deserve to be given the chance to complete the order.

Even so, I should point out that if this particular lab fails to deliver by the absolute deadline I for one will not be personally nor recommending anyone else use them ever again for any custom synthesis; and I have already told them this.

YADAYADA - Regards the ISRIB Group Buy, since you are managing that particular Group Buy it is entirely up to you how you wish to proceed. Whatever action you choose, please kindly note that I will still be very happy to assist you by managing the shipping. All I will require is the ISRIB bulk quantity, the participant list (including names and mailing addresses where to mail the individual samples), and the total shipping costs (= $145).

I don't see why u need to resort to deadline and take a hit financially as you have been reliable in the past. If you do refund, i would be happy to receive the payment back minus the transaction fees, this is clearly a scenario of of your control. At least the lab is being honest if they can't complete the synthesis.

I urge others to offer the same, as charging the group buy organiser the transaction fee would put off future reliable people from to organise them.

Edited by Major Legend, 25 December 2013 - 12:36 PM.

[MizTen]

Though I'm not on this group buy, that would be my response also.

[Amorphous]

Cancelling the order would be a lost-lost for everybody. I don't really mind to wait for it since there is no hurry to try this stuff any way - it is already available from NSN. Getting a quality product is more important in my opinion. Even extending for 2 more weeks from 1/7/14 is okay with me.

[tritium]

Is this the same lab which is doing the NSI-189 2nd group buy?

[sparkk51]

Is this the same lab which is doing the NSI-189 2nd group buy?

I think so, but they also did the first one. You need to realize this chemical is apparently much more difficult to synthesize than NSI-189.

[David J Meneses R]

After 4 hour of full reading i have some questions:
-there is at least 3 suppliers like New star noortropics , noortropic depot, other at UK that allready sell PRL 8 53. If is so complicate to synthesize, what are this company selling? A rename noortropic or a expensive placebo?
-if NSN or Ndepot are selling real PRL 8 53 why your labs fail? People of this forum was cheat?
-And what about experience toll for some users in the last part of this forum... Wasnt real too?

[megatron]

After 4 hour of full reading i have some questions:
-there is at least 3 suppliers like New star noortropics , noortropic depot, other at UK that allready sell PRL 8 53. If is so complicate to synthesize, what are this company selling? A rename noortropic or a expensive placebo?
-if NSN or Ndepot are selling real PRL 8 53 why your labs fail? People of this forum was cheat?
-And what about experience toll for some users in the last part of this forum... Wasnt real too?

I believe NSN's supplier was OK with a slightly less purity. Their supplier/company is also already fully settled and is a relatively large organization in China. They have easier access to chemicals, and hasn't been going through a re-organization of their company, as our manufacturer has.

[therein]

I am a part of this group buy and I personally am perfectly fine with waiting. This lab is clearly honest as they easily could have shipped us a lower quality product yet they didn't.

If we decide to cancel our order with this lab, I don't want ScienceGuy to take a financial hit by paying the transaction fees out of his pocket. He has been a valuable part of this community and he shouldn't lose money because he wanted to help us with the synthesis. I would be perfectly content with getting my money back minus the transaction fees and anything that ScienceGuy had to spend.

Edited by therein, 03 January 2014 - 01:27 PM.

[megatron]

I am a part of this group buy and I personally am perfectly fine with waiting. This lab is clearly honest as they easily could have shipped us a lower quality product yet they didn't.

If we decide to cancel our order with this lab, I don't want ScienceGuy to take a financial hit by paying the transaction fees out of his pocket. He has been a valuable part of this community and he shouldn't lose money because he wanted to help us with the synthesis. I would be perfectly content with getting my money back minus the transaction fees and anything that ScienceGuy had to spend.

Of course he's not going to take the hit. It's only fair that everyone shares the loss, if it comes to that.

Edited by Megatrone, 03 January 2014 - 03:53 PM.

[therein]

I am a part of this group buy and I personally am perfectly fine with waiting. This lab is clearly honest as they easily could have shipped us a lower quality product yet they didn't.

If we decide to cancel our order with this lab, I don't want ScienceGuy to take a financial hit by paying the transaction fees out of his pocket. He has been a valuable part of this community and he shouldn't lose money because he wanted to help us with the synthesis. I would be perfectly content with getting my money back minus the transaction fees and anything that ScienceGuy had to spend.

Of course he's not going to take the hit. It's only fair that everyone shares the loss, if it comes to that.

I remember he said he would be happy to pay for the transaction fees etc in case the order gets cancelled. That's why we have been saying that it's fine, and we can cover it instead.

[ScienceGuy]

UPDATE:

Hi Everyone, just to let you know, since the deadline has now come and gone I have contacted the lab and have requested an update regards whether or not they have succeeded in completing the synthesis. Thank you for everyone's considerable patience and understanding, and most generous offer to help by covering the transaction fees should this particular synthesis order have to be cancelled.

I will post what the lab says just as soon as I receive a reply.

[FW900]

UPDATE:

Hi Everyone, just to let you know, since the deadline has now come and gone I have contacted the lab and have requested an update regards whether or not they have succeeded in completing the synthesis. Thank you for everyone's considerable patience and understanding, and most generous offer to help by covering the transaction fees should this particular synthesis order have to be cancelled.

I will post what the lab says just as soon as I receive a reply.

Thank you for the update, ScienceGuy! I, as another member of this group buy, would also like to state that I have no problem at all with having some of my refund deducted to cover the transaction fee. The transaction fee was well worth it, this group buy has created such an interest in PRL-8-53, that it's available elsewhere.

[noot_in_the_sky]

If the family of the Doc is ok with digitizing his papers, I'm willing to help for free and upload them to the net.


Could it be that the reason research on PRL 8-53 & PRL 8-147 stop was because this compounds are difficult to synthesis? If with todays technology we are having trouble making these things, then back then it may have been much harder and so not economical viable.

[ScienceGuy]

UPDATE:

Hi everyone,

I have not received a reply from the lab yet regarding the PRL-5-83 custom synthesis order... I think, like many European companies, they did not start work again until yesterday, MONDAY 13th JANUARY. I have sent them another email asking them to respond, so I am hoping to receive a reply by the end of this week

[megatron]

I think, like many European companies, they did not start work again until yesterday, MONDAY 13th JANUARY.

If that's the case, I think it is quite amateurish. They must know that they're overdue by several months!? You don't take a full vacation (even if it's Christmas) when you know that you've been given a final deadline, and not fulfilling this may lead to a major loss of future orders. This is starting to get a little unprofessional I think. If they're not able to reach the satisfactory purity, then they can just say so.

[ScienceGuy]

I think, like many European companies, they did not start work again until yesterday, MONDAY 13th JANUARY.

If that's the case, I think it is quite amateurish. They must know that they're overdue by several months!? You don't take a full vacation (even if it's Christmas) when you know that you've been given a final deadline, and not fulfilling this may lead to a major loss of future orders. This is starting to get a little unprofessional I think. If they're not able to reach the satisfactory purity, then they can just say so.

I wholeheartedly agree with you.

I have given them an absolute deadline of this FRIDAY 17th JANUARY to confirm whether or not they have completed the synthesis. The behaviour is bizarre and extraordinary, especially given the previous track record of 100% reliability. Let's see what transpires between now and Friday...

[leftside]

After two years of experimenting with noops, this is my favorite so far. 10mg in the morning and I'm good to go. Been using it on and off now for over a month and comparing it to Coluracetam. PRL-8-53 works better for me. Coluracetam seems to drain me a little.

[Nattzor]

After two years of experimenting with noops, this is my favorite so far. 10mg in the morning and I'm good to go. Been using it on and off now for over a month and comparing it to Coluracetam. PRL-8-53 works better for me. Coluracetam seems to drain me a little.

Have you tried combining it? Most people seem to like colu + PRL.

[noot_in_the_sky]

I think, like many European companies, they did not start work again until yesterday, MONDAY 13th JANUARY.

If that's the case, I think it is quite amateurish. They must know that they're overdue by several months!? You don't take a full vacation (even if it's Christmas) when you know that you've been given a final deadline, and not fulfilling this may lead to a major loss of future orders. This is starting to get a little unprofessional I think. If they're not able to reach the satisfactory purity, then they can just say so.

I wholeheartedly agree with you.

I have given them an absolute deadline of this FRIDAY 17th JANUARY to confirm whether or not they have completed the synthesis. The behaviour is bizarre and extraordinary, especially given the previous track record of 100% reliability. Let's see what transpires between now and Friday...

Bizarre indeed, perhaps they been bussy increasing their long term memory . Good thing I skip this group buy and went for NSN instead.

[ScienceGuy]

Coluracetam seems to drain me a little.

What dosage and frequency did you take COLURACETAM?

[m0sy]

Hello gents,
After a month of testing here is what I have observed.

Here is a basic profile of my relevant information.
(
I am in my early twenties.
I am male.
I weigh 154 lbs.
I consider my diet relatively “healthy”. I prepare all of my meals with the one exception of a dinner over the weekend.
I exercise five days a week at an hour and twenty minutes each workout period.
My sleep schedule is… peculiar. I sleep at three separate times in the day. The largest block of time is a period of 3 hours. The second block of time is a period of 1.5 hours. The third and last block of time is a period of twenty minutes. I have noticed that the total amount of time slept can very between +30 and -30 minutes. After the first block of sleep, I take the second block 1.5-3.5 hours afterwards. Ten hours after awaking from this second block I take my 20 minute nap.
(
My daily stack (prior to the experiment):
2.0g Piracetam
1.5g Oxiracetam
1.0g Aniracetam
Taken every six hours.

32g of whey protein
5g of creatine
Taken post workout

250mg ALA
2 drops of Semax blue
Taken every 8 hours.
)
(
Every three days:
150mg 5-htp (before the 3hr sleep block)

Galantamine (8mg)
Choline Bitartrate (200mg)
(Before the 1.5 hour sleep block)
For lucid dreaming purposes.
)
)

For my first design, I determined that the testing period would be 4 weeks (and a week prior to clear out my system). The profile above persisted throughout this 4 week experiment (with the exception of the supplements).

For the first two weeks I decided to take 10mg of PRL-8-53 every twelve hours sublingually.

For the last two weeks I decided to take 10mg of PRL-8-53 every twelve hours orally.

The PRL-8-53 was purchased from NSN. PRL-8-53 is a white powdery substance that has the habit of clumping up into small granules. Its consistency reminded me of Aniracetam. On the scale of wretchedness, PRL-8-53 tasted like a 4. Its flavour is very distinct, like Adrafinil and Semax, in that its character clearly remains in the mind. On first contact with the tongue it is quite bitter. Almost instantaneously after this observation a bite of numbness is delivered. To complete this cocktail of sensation, a chemical-like aftertaste washes over the tongue. At 10mg (sublingually), the numbness completely subsides after thirty minutes. Each dose of Prl-8-53 was taken on an empty stomach.

It is important to note that I was primarily interested in observing the physical effects of PRL-8-53 (I decided that my second design would explore its cognitive effects).

PRL-8-53 is slightly stimulating however this is likely due to the presence it brings about from its effect on the tongue. About an hour after dosing I would consistently notice a tingle in my cheeks. At 10mg (sublingually) the physical effects, other than those already described, were barely perceptible. All I can really attribute to this is that I felt “different” (I could tell that there was something acting on my system).

At the beginning of the second week I could no longer notice this “difference”. On the last two days of the second week I had a headache.

In response to the headache, I decided to take a week break before continuing the second half of the experiment.

When taken orally at 10mg I could not detect anything from PRL-8-53.
After two weeks I did not get a headache.

There is one curious thing I feel that I should mention. For three months prior to the experiment I had been learning Japanese (I continued learning it through the experiment). On the fourth day of the first phase I noticed that during my practice session the language had a taken on a more “familiar” appearance. This familiarity had the benefit of making it easier to learn by allowing the process to seem more natural. What is interesting is that this has remained even after finishing the experiment.

My intuitive conclusion for PRL-8-53 is that it should be taken in larger doses and less often.


-M

[leftside]

After two years of experimenting with noops, this is my favorite so far. 10mg in the morning and I'm good to go. Been using it on and off now for over a month and comparing it to Coluracetam. PRL-8-53 works better for me. Coluracetam seems to drain me a little.

Have you tried combining it? Most people seem to like colu + PRL.

Yes. It's good, but I feel a little more burnt out at the end of the week compared to just taking the PRL alone.

Edited by leftside, 16 January 2014 - 06:21 PM.

[leftside]

Coluracetam seems to drain me a little.

What dosage and frequency did you take COLURACETAM?

10mg twice a day and then 10 mg once a day. I retried 10mg col + 10mg prl this morning. It is a good combo, but has the tendency to burn me out at the end of the week. I feel prl alone is sufficient. The only other things I take right now are a good TongKat Ali, American Ginseng straight from the farm here in Canada, and Yerba Mate. Though I haven't taken the Ginseng and Yerba Mate today as the prl + col is more than enough.

[leftside]

Certainly a little more tired than usual today after taking the col yesterday. This is certainly not a take "every day" type substance for me. Every now and then will be ok. I can take prl every day midweek with a break at weekends no problem. Going to try idra next week,

Edited by leftside, 17 January 2014 - 06:13 PM.

[MasterHerb]

I think, like many European companies, they did not start work again until yesterday, MONDAY 13th JANUARY.

If that's the case, I think it is quite amateurish. They must know that they're overdue by several months!? You don't take a full vacation (even if it's Christmas) when you know that you've been given a final deadline, and not fulfilling this may lead to a major loss of future orders. This is starting to get a little unprofessional I think. If they're not able to reach the satisfactory purity, then they can just say so.

I wholeheartedly agree with you.

I have given them an absolute deadline of this FRIDAY 17th JANUARY to confirm whether or not they have completed the synthesis. The behaviour is bizarre and extraordinary, especially given the previous track record of 100% reliability. Let's see what transpires between now and Friday...

Updates?

[therein]

I am wondering the same. Any news from our Polish friends?

I am still occasionally using the PRL I got from NSN, and it is just great. This compound is definitely under-appreciated. I can go as far as saying that I get a permanent cognitive boost from it.