1023 replies to this topic

[sthira]

Anyone else feel nothing?

Yes. 5 liters worth over the past couple of years. I like the taste, but no effects, AFAICT, except for a possible sleep enhancing effect. Probably just the olive oil, though.

Are you sure there's c60 in it? If it's at the typical commercial concentration of 0.8mg/ml, that would be 4000 mg; about 2 grams a year. Are you making it, or do you buy it?

I make my own. I've never noticed anything positive or negative after taking it. But I'm healthy, athletic, lean, and have no problems other than a torn meniscus. C60 doesn't help grow avascular cartilage, that much I know.

[Kalliste]

I've used it for a couple of months but I am unable to discern effects from placebo. But I started this biological wager now when I'm 30 and healthy to reap long-term mortality benefits, not to gain performance although that would be welcome. I have NOT kept very strict control of my physical fitness during this period and I've done other things that are confounding such as MitoQ, 5000iu D-vitamin, raw turmeric roots etc.

I guess older individuals should notice more effect so I'm not worried as long as I don't notice anything nasty.

 

 

 

 

 

Anyone else feel nothing?

Yes. 5 liters worth over the past couple of years. I like the taste, but no effects, AFAICT, except for a possible sleep enhancing effect. Probably just the olive oil, though.

Are you sure there's c60 in it? If it's at the typical commercial concentration of 0.8mg/ml, that would be 4000 mg; about 2 grams a year. Are you making it, or do you buy it?

I make my own. I've never noticed anything positive or negative after taking it. But I'm healthy, athletic, lean, and have no problems other than a torn meniscus. C60 doesn't help grow avascular cartilage, that much I know.

 

 

It might be able to help. Not sure how relevant this study is, can't find full text of it.

P297 WATER-SOLUBLE FULLERENE (C60) PREVENTS DEGENERATION OF ARTICULAR CARTILAGE IN OSTEOARTHRITIS

[Turnbuckle]

 

 

 

It might be able to help. Not sure how relevant this study is, can't find full text of it.

P297 WATER-SOLUBLE FULLERENE (C60) PREVENTS DEGENERATION OF ARTICULAR CARTILAGE IN OSTEOARTHRITIS

 

 

 

http://onlinelibrary.../art.22917/full

 

Results

 

C60 (100 μM) inhibited the catabolic stress–induced production of matrix-degrading enzymes (matrix metalloproteinases 1, 3, and 13), down-regulation of matrix production, and apoptosis and premature senescence in human chondrocytes in vitro. In rabbits with OA, treatment with water-soluble C60 significantly reduced articular cartilage degeneration, whereas control knee joints showed progression of cartilage degeneration with time. This inhibitory effect was dose dependent, and was superior to that of HA. Combined treatment with C60 and HA yielded a significant reduction in cartilage degeneration compared with either treatment alone.

 

 

Considering that oil soluble C60 doesn't seem to help cartilage--at least from the reports by users here--it might be better to take both the oil and water soluble versions.

Edited by Turnbuckle, 24 October 2014 - 05:55 PM.

[sthira]

What do you mean by take both oil & the water soluble versions? What is the water version of c60? Water soluable c60 injections directly into damaged cartilage?

[Turnbuckle]

What do you mean by take both oil & the water soluble versions? What is the water version of c60? Water soluable c60 injections directly into damaged cartilage?

 

The water version: C60(OH)24 

[tintinet]

SES Carbon 60, 99.95+ %, ultra pure Vacuum oven dried, 1 g mixed with 1.5 L high quality EVOO.

 

https://flic.kr/p/pvLhiy

 

 

 

 

 

 Anyone else feel nothing?

 

Yes. 5 liters worth over the past couple of years. I like the taste, but no effects, AFAICT, except for a possible sleep enhancing effect.  Probably just the olive oil, though.

 

Are you sure there's c60 in it?  If it's at the typical commercial concentration of 0.8mg/ml, that would be 4000 mg; about 2 grams a year.  Are you making it, or do you buy it?

 

 

Edited by tintinet, 24 October 2014 - 11:31 PM.

[niner]

SES Carbon 60, 99.95+ %, ultra pure Vacuum oven dried, 1 g mixed with 1.5 L high quality EVOO.

 

https://flic.kr/p/pvLhiy

That's the same thing that I've done, although lately I'm making small batches.  Exact same c60 that I used.  Yours looks like mine did.

[aribadabar]

 

So I've mentioned elsewhere, I'm hyposmic. I lost much of my sense of smell in a severe infection episode last year. So unfortunately, I can't be sure whether it's just due to that, or something more, along the lines of the link between hyposmia and increased morbidity.

 

But for the past week or so, I've noticed increasing episodes of normosmia (normal smell). It would come and go for several seconds here and there, which might have been my imagination. But just an hour ago, I opened the door to step outside for a break. A light wind burst into my home. I smelled the smell of fresh air, which I've hardly noticed in months. I just got over a modest cold, so perhaps this made the contrast all the more dramatic. So I stood outside my door like a mindless idiot, gasping huge inhalations of air for several minutes, trying to detect every single subtle odor wafting along with it. It wasn't perfect. For one thing, I smelled a bit of sun lotion even though there was none around. (This might be because I've used sun lotion as an odor sensitivity test, so I have more circuitry for it.) Nevertheless, I was so thrilled with the experience, that I spent the next several minutes learning what my home actually smells like. I must have gone through half the fridge testing the odors of various foods, which was sort of like walking through my culinary past. I was equally ecstatic to open my closet, only to be inundated with the odor of cardboard boxes, as mundane as that may sound to you.

 

I don't know of any reason why this should happen, or whether it will continue to improve, apart from my own natural stem cell activity slowly cranking away.

 

At the same time, I've started noticing periods up to a minute or more where I feel more connected to the world, like when I was younger. I'm more "here". There's absolutely no way to quantify this, but it's unmistakable.

 

Maybe it's all coincidence, as I seem to remember reading another post in which the poster continued to have hyposmia despite c60oo therapy. But I think it's worth reporting here nonetheless.

 

This post made me focus on my olfactory function and today, 1 day after my weekly C60 dose, I sense a heightened sense of smell than previous days. I don't think I have any loss of smell but today it is markedly stronger as I sense some very subtle ones.

Same sensation occurred a couple of weeks ago but then I did not recall if it was soon after my C60 intake.

 

I will try to keep note to see if it is there is any correlation .

 

Update:

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

[resveratrol_guy]

Update:

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

So what does this really mean? Is c60oo protecting newly generated olfactory neurons which replace damaged ones, but only for a short time window until they die off again? (So yours die off to normal population levels, and mine die off to insufficient levels.) Or is this much simpler, like c60oo making those neurons function more efficiently? More importantly, how can we extend the window of effect? (Nuvigil, nicotine, and cacao come to mind. This is an ongoing central question here: we need to know how to keep the energy/performance/speed boost of c60oo potentiated for the long term, as opposed to merely the protective effects.)

 

Make sure you're getting sufficient selenium, which is related to neurological health (and cancer protection). But this is basic and probably won't achieve the long term potentiation we're seeking.

 

BTW I started another c60oo microtrial: I have never been able to eat much chocolate without feeling nauseous, headachy, and somewhat depressed several hours later. I'm naively hoping that c60oo will ameliorate this, in the same way that it seems to increase alcohol tolerance. I really would like to get all the advantages of dark chocolate -- medical and gastronomic -- as well as the massive phosphatidyl serine dose in the soy lethicin (which might be inaccessible though), without having to resort to cacao pills. (I figured I might as well experiment with cacao, one way or another, while waiting for my delayed stem cell therapy.)

 

Edited by resveratrol_guy, 01 November 2014 - 05:50 PM.

[mikey]

Update:

 

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

 

I take 7 mg every morning.

 

Continuous dosing works best for me, for several benefits, as noted on my profile page.

[mikey]

 

Update:

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

So what does this really mean? Is c60oo protecting newly generated olfactory neurons which replace damaged ones, but only for a short time window until they die off again? (So yours die off to normal population levels, and mine die off to insufficient levels.) Or is this much simpler, like c60oo making those neurons function more efficiently? More importantly, how can we extend the window of effect? (Nuvigil, nicotine, and cacao come to mind. This is an ongoing central question here: we need to know how to keep the energy/performance/speed boost of c60oo potentiated for the long term, as opposed to merely the protective effects.)

 

Make sure you're getting sufficient selenium, which is related to neurological health (and cancer protection). But this is basic and probably won't achieve the long term potentiation we're seeking.

 

BTW I started another c60oo microtrial: I have never been able to eat much chocolate without feeling nauseous, headachy, and somewhat depressed several hours later. I'm naively hoping that c60oo will ameliorate this, in the same way that it seems to increase alcohol tolerance. I really would like to get all the advantages of dark chocolate -- medical and gastronomic -- as well as the massive phosphatidyl serine dose in the soy lethicin (which might be inaccessible though), without having to resort to cacao pills. (I figured I might as well experiment with cacao, one way or another, while waiting for my delayed stem cell therapy.)

 

 

You might try D-Ribose as a sweetener - lowers blood sugar/fuels ATP - with organic cacoa. I mix it in Organic Valley fully pasture-raised heavy cream, for the K2 and other fat-soluble nutrients, found in only tiny doses in grain-fed cream. K2 has just been patented to reverse plaque, based on a large human study that will be published soon. It's in the press already.

[aribadabar]

 

Update:

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

So what does this really mean? Is c60oo protecting newly generated olfactory neurons which replace damaged ones, but only for a short time window until they die off again? (So yours die off to normal population levels, and mine die off to insufficient levels.) Or is this much simpler, like c60oo making those neurons function more efficiently? More importantly, how can we extend the window of effect? (Nuvigil, nicotine, and cacao come to mind. This is an ongoing central question here: we need to know how to keep the energy/performance/speed boost of c60oo potentiated for the long term, as opposed to merely the protective effects.)

 

Make sure you're getting sufficient selenium, which is related to neurological health (and cancer protection).

I don't feel knowledgeable enough to interpret the cause of this effect. I may try a semi-weekly dosage to see if this effect is consistent at the shorter timeframes.

 

Thanks for the selenium suggestion - I already take 100 mcg/d + 2-3 brazil nuts 2-3 times a week so I think it should be sufficient.

[aribadabar]

 

Update:

 

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

 

I take 7 mg every morning.

 

Continuous dosing works best for me, for several benefits, as noted on my profile page.

 

 Have you noticed amplification of your sense of smell since you started dosing too?

[resveratrol_guy]

You might try D-Ribose as a sweetener - lowers blood sugar/fuels ATP - with organic cacoa. I mix it in Organic Valley fully pasture-raised heavy cream, for the K2 and other fat-soluble nutrients, found in only tiny doses in grain-fed cream. K2 has just been patented to reverse plaque, based on a large human study that will be published soon. It's in the press already.

 

Kudos for mentioning the K2/plaque connection, which IMO should be synergistic with c60oo if it reverses endothelial damage like MitoQ did in mice. FYI Jarrow (or other) K2 MK7 pills may be cheaper and easier for some people. (Note that the MK7/MKwhatever issue really matters according to neurobiologist and nutrition expert Stephan Guyenet.) And for the uninitiated, please not confuse K1 with K2. K2 is so different that it should have been called "vitamin L"!

 

For my part, I couldn't care less about sweetness (as I sit here chomping on steamed bitter gourd with K2-bearing cheddar). But thanks for the tip, which no doubt will interest all the sweettooths out there as another option for escaping table sugar. [EDIT: Apparently, D-ribose has cardiovascular benfits as described this NIH paper, but putting "d-ribose" in the search dialog on Longecity reveals a complex picture worth reading. Presumably its effects would be orthogonal to c60oo due to water-vs-oil solubility.]

 

My cacao experiment results are as follows (100g 70% dark Green & Black organic, synchronous with about 3 mg of c60oo):

 

1. No postchocolate nausea or depression.

 

2. Mild postchocolate headache (about 20 hours later).

 

3. No chocolate/caffeine jitters.

 

4. Superficial but barely passable sleep.

 

So, c60oo probably helped. But I think I'll stick to cacao pills.

 

Edited by resveratrol_guy, 02 November 2014 - 03:00 PM.

[resveratrol_guy]

I don't feel knowledgeable enough to interpret the cause of this effect. I may try a semi-weekly dosage to see if this effect is consistent at the shorter timeframes.

 

Thanks for the selenium suggestion - I already take 100 mcg/d + 2-3 brazil nuts 2-3 times a week so I think it should be sufficient.

 

 

OK if anything improves please report. Changing dosing is the most obvious way in which we might extend the effect, in addition to taking synergistic supplements. I think it's safe to say that olfactory function is a canary for general neurological health here, so the significance of this endeavor may extend well beyond the sense of smell.

 

It should be noted that selenosis is a risk with excessive selenium ingestion. That, and brazil nuts have a history of (radioactive) radium contamination according to Google. I've actually taken a Geiger counter to several different brazil nut samples, and noticed nothing obviously above background, but maybe I'm just lucky.

 

[mikey]

 

 

Update:

 

 

I took my weekly 5mg dose and within ~2hrs got the boost of my ,otherwise normal, olfactory function again. This time, however, it lasted shorter than last week - maybe a couple of hours after the C60 intake.

 

Maybe that's as high as it can get at this dosage...

 

 

I take 7 mg every morning.

 

Continuous dosing works best for me, for several benefits, as noted on my profile page.

 

 Have you noticed amplification of your sense of smell since you started dosing too?

 

 

I haven't noticed any change.

[mikey]

 

You might try D-Ribose as a sweetener - lowers blood sugar/fuels ATP - with organic cacoa. I mix it in Organic Valley fully pasture-raised heavy cream, for the K2 and other fat-soluble nutrients, found in only tiny doses in grain-fed cream. K2 has just been patented to reverse plaque, based on a large human study that will be published soon. It's in the press already.

 

Kudos for mentioning the K2/plaque connection, which IMO should be synergistic with c60oo if it reverses endothelial damage like MitoQ did in mice. FYI Jarrow (or other) K2 MK7 pills may be cheaper and easier for some people. (Note that the MK7/MKwhatever issue really matters according to neurobiologist and nutrition expert Stephan Guyenet.) And for the uninitiated, please not confuse K1 with K2. K2 is so different that it should have been called "vitamin L"!

 

The 2008 articles is not up on the latest research. Vitamin K2 (MK-7) has a half-life of about 3 days, where MK-4 is about 2 hours. MK-7 is the one that most current research is focusing on and a new patent was granted for reversing HUMAN plaque. MK-4, at very high doses reversed rat plaque, and does have value, but MK-7 is what I take - 300 mcg/day. Japanese get something like 900 mcg a day from natto, a fermented soy food and have less CVD than Americans, who tend to be grossly deficient in vitamin K2 (MK-7).

 

Typical Americans don't get much.

Edited by mikey, 02 November 2014 - 08:22 PM.

[StevesPetRat]

This post made me focus on my olfactory function and today, 1 day after my weekly C60 dose, I sense a heightened sense of smell than previous days. I don't think I have any loss of smell but today it is markedly stronger as I sense some very subtle ones.

Haha, oh man, I have been noticing how... unpleasantly yeasty / sour... some of my friends smell lately. Guess this could be chalked up to the C60?

[cani!]

Quite frankly, I was a total disbeliever about C60oo but decided to give it a try. I don't have health issues and I'm in really good shape. I play soccer and run tracks so I train 6 to 12 times a week (depending on where I am on my season).

 

My base level of fitness was pretty good but as most people, I have lagging injuries that makes it hard to train as much as I would like. Specifically, I have horrible shin splints that I've endured since I was 18. Ice and compression socks usually works and allow me to train but I can't run as much as I would like, can't do plyos as much as I would like and have to take rest periods.

 

Anyways, after reading about C60oo and seeing people take huge doses for a long time I tried it. It seemed safe enough provided cycling and usual caution. Specifically, the log of a fellow athlete (m500?) who posts here got me convinced. 

 

Long story short: my shin splint are gone! After the first week of treatment with 6 mg a week, they just disappered completely. I am absolutely not kidding. They haven't returned yet neither. So i have no idea why but C60oo seems to be a very potent anti-inflammatory.

 

My endurance also increased and I was able to run 1 mile an hour faster on my 20 k runs.

 

I can't say it affected my strength or my explosiveness but I recover much faster from workouts.

 

I'm not prone to the placebo effect: modafinil doesn't work on me and I actually measured my output and performances before starting C60 and after.

 

TLDR: cured shin splints in the first week, never got them back. Boost in endurance on fit athlete. 

Edited by cani!, 06 November 2014 - 03:26 PM.

[BigPine]

Quite frankly, I was a total disbeliever about C60oo but decided to give it a try. I don't have health issues and I'm in really good shape. I play soccer and run tracks so I train 6 to 12 times a week (depending on where I am on my season).

 

My base level of fitness was pretty good but as most people, I have lagging injuries that makes it hard to train as much as I would like. Specifically, I have horrible shin splints that I've endured since I was 18. Ice and compression socks usually works and allow me to train but I can't run as much as I would like, can't do plyos as much as I would like and have to take rest periods.

 

Anyways, after reading about C60oo and seeing people take huge doses for a long time I tried it. It seemed safe enough provided cycling and usual caution. Specifically, the log of a fellow athlete (m500?) who posts here got me convinced. 

 

Long story short: my shin splint are gone! After the first week of treatment with 6 mg a week, they just disappered completely. I am absolutely not kidding. They haven't returned yet neither. So i have no idea why but C60oo seems to be a very potent anti-inflammatory.

 

My endurance also increased and I was able to run 1 mile an hour faster on my 20 k runs.

 

I can't say it affected my strength or my explosiveness but I recover much faster from workouts.

 

I'm not prone to the placebo effect: modafinil doesn't work on me and I actually measured my output and performances before starting C60 and after.

 

TLDR: cured shin splints in the first week, never got them back. Boost in endurance on fit athlete. 

How long ago did you take your first dose of C60? If you kept on taking it, did the effects gradually wear off?

 

I'm also a track runner. My times are decent but not spectacular (55 second 400, 2:11 800 earlier this year). I'm currently in good health, quite young, and don't have any injuries, so I'm wondering how much improvement I can get.

[cani!]

 

Quite frankly, I was a total disbeliever about C60oo but decided to give it a try. I don't have health issues and I'm in really good shape. I play soccer and run tracks so I train 6 to 12 times a week (depending on where I am on my season).

 

My base level of fitness was pretty good but as most people, I have lagging injuries that makes it hard to train as much as I would like. Specifically, I have horrible shin splints that I've endured since I was 18. Ice and compression socks usually works and allow me to train but I can't run as much as I would like, can't do plyos as much as I would like and have to take rest periods.

 

Anyways, after reading about C60oo and seeing people take huge doses for a long time I tried it. It seemed safe enough provided cycling and usual caution. Specifically, the log of a fellow athlete (m500?) who posts here got me convinced. 

 

Long story short: my shin splint are gone! After the first week of treatment with 6 mg a week, they just disappered completely. I am absolutely not kidding. They haven't returned yet neither. So i have no idea why but C60oo seems to be a very potent anti-inflammatory.

 

My endurance also increased and I was able to run 1 mile an hour faster on my 20 k runs.

 

I can't say it affected my strength or my explosiveness but I recover much faster from workouts.

 

I'm not prone to the placebo effect: modafinil doesn't work on me and I actually measured my output and performances before starting C60 and after.

 

TLDR: cured shin splints in the first week, never got them back. Boost in endurance on fit athlete. 

How long ago did you take your first dose of C60? If you kept on taking it, did the effects gradually wear off?

 

I'm also a track runner. My times are decent but not spectacular (55 second 400, 2:11 800 earlier this year). I'm currently in good health, quite young, and don't have any injuries, so I'm wondering how much improvement I can get.

 

 Those are good times! Congratulations! Personnaly, I never post my time online not to discourage anyone but kudos to you!

 

As for your question, I've been on it two months or so at 3 mg bi-weekly. So far, the effects have begun tapering and I plan to stop taking it for a while to see how long it works.

 

As for you, why risk it? It is really up to you.

 

Also, I noticed no improvement in my 100, 200 meters time. When I do 400 or 800 repeats, I'm a bit less winded. It is on the longer run that it really shines (5 to 20 k). I do a bit of everything since I'm off season.  

 

I have two theory on method of action:

 

1. Increase oxygen levels (I don't know how it would happen but the effect on recovery and inflammation is on par with hyperbaric chamber treatment)

2. Repairs damage mithochondria. I took statins for a short while and immediatly felt my muscle aching. I stopped but I think some damage was done. Maybe it is just a reversal of that type of damage. 

 

Anyways, It is a risky substance but it sure beats drinking gallons of beet juice lol!

 

Good luck!

 

 

[Astroid]

My C60 Update.... It will be 4 weeks on Saturday.. since I started using C60. I reduced the dosage to 2 CC a day. I've been busy painting a couple of rehabs.  3-7 hours most days over the last 10 days... so this helps evaluate the C60 test.  

 

I don't know about endurance.. as I am not lifting weights.. but I have gotten tired some.. nothing excessive..  when I paint 5-7 hours.. I am usually on a ladder up and down.. or squatting down to get the baseboards... that is playing havoc with my knees.

 

When I awake after painting.. I am not sore or in pain.. So that is wonderful..  

 

An ex-nurse who is really into the chemistry of the body and has told me several times that DMSO is a great carrier of very small partials below a certain size.. suggested rubbing C60 and then add DMSO to joints.  Finally I did since a couple of knuckles in my right hand had gotten stiff from painting. I tried it a couple of days ago.. and have to say they are about 50% the next morning.  

 

I applied the C60 again last night to 2 right & 2 left knuckles.. then added DMSO.. only a drop of each.. this morning they feel normal... and the ones I did not apply it to feel a bit stiff... So it looks like a good combo.

 

My ligaments behind the knee seems to have felt it after working last Friday night so long.. on a ladder.. twisting.. turning..  I am sure the climbing did not help either.. I took Saturday off, slept in and they felt better the next day.  Now 5 days later.. I also applied the DMSO combo to the ligaments behind my knees and I have no tenderness or stiffness in them.. but I have not painted or been on a ladder the last couple of days either.. However they are greatly improved compared to yesterday. 

 

* *  

 

  The top of my ears, and especially the right one..  has had some rough skin for several years.. There was one small spot on the right ear that had tough skin that I could never peel off. I mean it was attached by the roots and was tender.  Well I put the C60 on it.. by accident while applying it to my scalp.. and noticed the left ear's skin became normal within a couple of days !  So then I deliberately applied it to my right ear a few times now.. and it improved.. over a week.. today it feels like normal skin now !  My Mother had skin cancer on her ear and let it go.. it ended up killer her after about 5 years.  She refused to admit it was an issue.

 

  So this stuff really works wonders..  The ear skin issue always worried me. I had used iodine and gotten some improvement, but nothing like this. Wow. 

[niner]

 

 

TLDR: cured shin splints in the first week, never got them back. Boost in endurance on fit athlete. 

 

How long ago did you take your first dose of C60? If you kept on taking it, did the effects gradually wear off?

 

I'm also a track runner. My times are decent but not spectacular (55 second 400, 2:11 800 earlier this year). I'm currently in good health, quite young, and don't have any injuries, so I'm wondering how much improvement I can get.

 

As for your question, I've been on it two months or so at 3 mg bi-weekly. So far, the effects have begun tapering and I plan to stop taking it for a while to see how long it works.

 

As for you, why risk it? It is really up to you.

 

Also, I noticed no improvement in my 100, 200 meters time. When I do 400 or 800 repeats, I'm a bit less winded. It is on the longer run that it really shines (5 to 20 k). I do a bit of everything since I'm off season.  

 

I have two theory on method of action:

 

1. Increase oxygen levels (I don't know how it would happen but the effect on recovery and inflammation is on par with hyperbaric chamber treatment)

2. Repairs damage mithochondria. I took statins for a short while and immediatly felt my muscle aching. I stopped but I think some damage was done. Maybe it is just a reversal of that type of damage. 

 

Anyways, It is a risky substance but it sure beats drinking gallons of beet juice lol!

 

When you say 'bi-weekly', does that mean twice a week or every two weeks?

 

There's no evidence that c60-oo is a risky substance.   Absence of evidence is not evidence of absence, but it's already been in a lot more people than a new pharmaceutical before it's approved for sale.  The difference between c60-oo and a new pharmaceutical is that most of the people are not being monitored by a doctor.  However, a lot of the thousands of users have had annual bloodwork by now, and there haven't been any anomalies reported.  The riskiness of c60-oo is perhaps on par with most new pharmaceuticals that your doctor might give you.  Probably less risky than many of them.  We had another person with a statin injury that was fixed by c60-oo; that may have happened in your case as well.  It certainly seems to be mitochondrially active, and other fullerene compounds have been demonstrated to localize to the mitochondria.  It's a potent antioxidant, and is probably soaking up a lot of mitochondrial ROS.  Your hypothesis of increased oxygen levels is pretty attractive.  It would explain a lot of our observations of improvements in situations that involve hypoxia.  I guess this would involve some kind of significant increase in the oxygen carrying capacity of blood; I don't know what the mechanism would be for that.  An alternative explanation would be that c60 is improving the efficiency of oxidative phosphorylation in the mitochondria, so it's just using the existing oxygen more efficiently.

 

Your shin splint result is pretty interesting.  That doesn't seem to be a very well-understood problem.  Keep us posted on the status of that, and don't go out and abuse your legs right away.  We've had tons of weight lifters who injured themselves doing too many reps because c60 interferes with a particular kind of muscle fatigue.   So far, that seems to be the biggest risk of c60-oo use.  If c60 were masking the underlying problem with your shin splints, overuse might make things worse.  If you have any anti-shin splint exercises or technology, you might want to keep that up for a while.

[sthira]

[

An ex-nurse who is really into the chemistry of the body and has told me several times that DMSO is a great carrier of very small partials below a certain size.. suggested rubbing C60 and then add DMSO to joints.

SNIP

[size=4][font=arial]My ligaments behind the knee seems to have felt it after working last Friday night so long.. on a ladder.. twisting.. turning.. I am sure the climbing did not help either.. I took Saturday off, slept in and they felt better the next day. Now 5 days later.. I also applied the DMSO combo to the ligaments behind my knees and I have no tenderness or stiffness in them.. but I have not painted or been on a ladder the last couple of days either.. However they are greatly improved compared to yesterday.

I tried this (C60-oo rubbed in with DMSO) on my torn meniscus, and noticed nothing good. So it'll be interesting to check up on how it goes for you. For me, the DMSO just really dried the skin out on the knee, and this worried me. If it dries it out on top, what's it doing inside? Anyway, let's see what you discover.

[Logic]

...Your hypothesis of increased oxygen levels is pretty attractive.  It would explain a lot of our observations of improvements in situations that involve hypoxia.  I guess this would involve some kind of significant increase in the oxygen carrying capacity of blood; I don't know what the mechanism would be for that.  An alternative explanation would be that c60 is improving the efficiency of oxidative phosphorylation in the mitochondria, so it's just using the existing oxygen more efficiently...

I think looking at the myo-inositol trispyrophosphate (ITPP) thread may help to answer this question as ITPP increases the amount of oxygen taken up by blood.
Thedarkbobo is taking both.
Perhaps comparing his experiences to those of people taking ITPP only could be a useful although imprecise exercise?

I cant help thinking that stacking the two is a good idea as C60oo may reduce ROS damage from extra O2?

http://www.longecity...y-to-tis/page-3

[thedarkbobo]

I dont think that C60-OO increases oxygen levels, at least not by as much as ITPP. If it helps with oxygen utilisation - I don't think that anecdotal reports can help with that

 

My summary is that:

C60

makes me not feeling cold for some time after taking it - awesome I am not shaking anymore

helps in physical endurance and slightly mental performance(probably as "in healthy body lives healthy mind", so when body improves mind also does)

and then work related stuff...I have mostly sitting job, and I am under heavy pressure and probably stress in first week of every month. I don't think that C60 helped in that matter much, I was usually feeling tired, heart was tired, vision was quiet bad, however still better than without it. I would say 10-20% improvement in this area compared to no C60.

 

And now this month ITPP came in. Mental endurance went up by a lot, physical endurance too, feeling that every bit of yourself has oxygen hehe, but I had a strange feeling that I could literally burn myself if I decided to for example do some heavy exercises. Need to control what you get. My biggest gain was ability to read book before and after work, in train, when usually I was too tired to do so. Here comes the second factor - I recently bought glasses with all kinds of filters that can be - and they seem to reduce fatigue of eyes in work by um x/4. Brain is reading not only eyes, so it struck me that I was able to read (in tran, before and after work during heaviest workload week) smaller letters than usually, faster than usually. Hehe.
 

It's important to let yourself rest too, I forced myself to sleep 9 hours yesterday. After such week I am mentally tired anyway. Getting some rest. Feeling good. I was diagnosed with little heart valve problem few years ago so I take what might help... vitamins K+D, hawthorn and the above. It's much better.

Edited by thedarkbobo, 08 November 2014 - 11:16 AM.

[cani!]

Yeah, I did use both compound (ittp and c60) but never in conjunction unless the half life of c60 is a month. I was off c60 for a month when I tried ITTP and I really liked it. It is not banned in my association. Since it is my last year playing at that level I want to make sure I stay healthy and can keep up with the younger guys on my team :-) 

 

But anyways, I found some of the effects of both compound quite similar, mainly on performance and recovery time. I can usually push myself very hard in the gym and do heavy plyos, intervalls and agility drills 8 times a week (plus two practice and two sport specific session) before going into overtraining. My coach is always holding me back. I'm not talented at all but I train harder than anyone I've ever met. My PT monitors my resting heart rate and has me resting as soon as I seem to regress in performance. C60 and ITTP had similar effects on me in quantifiable terms, i.e., my heart rate dropped faster in between intervalls, my 5k, 10k and 20k times got better. My 20k time is very bad since I'm more of a sprinter but I like the challenge especially in the off-season. 

 

Now as for the mode of action of c60, I really don't know. One thing is for sure though, my shin splints are just gone. They never got back. I still do contrast baths and use compression socks/foam rollers just to make sure they don't come back. The team PT was amazed and wondered what I was doing. I mentionned nanotechnology and he freaked :-) My problem is relatively simple: my calves and thigh muscle are way too strong for my tendons and they pull too hard especially when I sprint. It causes micro-tears on my shin bone and stress fracture (every year around september I'm one month limping and off every type of training.)

 

Next year, I'm switching to olympic weighlifting or something like that and I don't want to run anytime again in my life lol!

 

Anyways, to get back on topic, c60 is an amazing anti-inflammatory and helps recovery time a lot. 

Edited by cani!, 10 November 2014 - 04:01 AM.

[smithx]

Just an update on my friend's 14 year old dog who had 1 oz of C60 olive oil over the course of 3-4 months ending about a year ago:

 

Before taking C60OO the dog seemed to be on it's last legs. It barely wanted to walk and would just sit around without moving much. It hadn't jumped off the back of my friend's station wagon in the previous 2 years.

 

I just saw this dog yesterday, and it was running around, barking, it jumped off the back of his new truck (!) and generally was acting like a healthy dog. It wasn't jumping around like a puppy, but it was active and alert.

 

So the effects of the C60OO, at least in this one anecdotal case, seem to last for a long time after it's discontinued.

 

After seeing this, I was very impressed and I told the story to a researcher friend of mine. He said "Hmm... so that means it may possibly be effective in dogs."  Good point.

 

 

[niner]

I told the story to a researcher friend of mine. He said "Hmm... so that means it may possibly be effective in dogs."  Good point.

 

And that's why he gets the big bucks.

[resveratrol_guy]

To the others with olfactory problems: in the interest of accelerating research (and because we don't get paid big bucks to make obvious deductions from dog studies), I've found that cacao seems to potentiate my sense of smell. Details here. If you try this at home, please post details. It bears repeating: we need to find a way to potentiate early c60oo effects for as long as possible; cacao may be part of the answer. For balance, here is a harsh critique of the recent "discovery" that cacao flavonols enhance memory. (I don't normally provide links to blogs, but in this case the author disagrees with published science for some good reasons.) That said, I think the author has underestimated the longterm mental benefits.

 

Edited by resveratrol_guy, 11 November 2014 - 04:21 PM.