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NSI-189

nsi-189

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#451 MetaMind

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Posted 27 April 2013 - 09:21 AM

So do you guys think we can give up the order in thex next week?
Is there a problem concerning price per gram coz of only 30 people buyin?

#452 OpaqueMind

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Posted 27 April 2013 - 11:41 AM

Well now that ScienceGuy is back it hopefully wont be too long before the order is placed! Ahhh my god I'm so excited for this chem. Having suffered from severe depression in the past, and experiencing persistent memory problems, I will most likely be a super-responder :-) Keep us updated Frosty!

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#453 Xenix

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Posted 27 April 2013 - 05:34 PM

Well now that ScienceGuy is back it hopefully wont be too long before the order is placed! Ahhh my god I'm so excited for this chem. Having suffered from severe depression in the past, and experiencing persistent memory problems, I will most likely be a super-responder :-) Keep us updated Frosty!


You still on Cerebrolysin?

#454 OpaqueMind

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Posted 27 April 2013 - 05:46 PM

Well now that ScienceGuy is back it hopefully wont be too long before the order is placed! Ahhh my god I'm so excited for this chem. Having suffered from severe depression in the past, and experiencing persistent memory problems, I will most likely be a super-responder :-) Keep us updated Frosty!


You still on Cerebrolysin?


I just finished my first full cycle of 4 weeks yesterday, so not any longer. But I will definitely begin another cycle in a few months. Why'd you wonder?

#455 Xenix

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Posted 28 April 2013 - 04:26 AM

Well now that ScienceGuy is back it hopefully wont be too long before the order is placed! Ahhh my god I'm so excited for this chem. Having suffered from severe depression in the past, and experiencing persistent memory problems, I will most likely be a super-responder :-) Keep us updated Frosty!


You still on Cerebrolysin?


I just finished my first full cycle of 4 weeks yesterday, so not any longer. But I will definitely begin another cycle in a few months. Why'd you wonder?


No reason, just curious.

#456 OpaqueMind

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Posted 28 April 2013 - 02:17 PM

Hey Sunshinefrost, can we have an update on what's going on?

You better not have legged it with our cash! (half-joking, half-concerned)

#457 MizTen

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Posted 28 April 2013 - 03:26 PM

Looks like the NSI-189 group buy is closed. I didn't notice what you all were up to, due to testing Sunifiram.

But if there's a spot open, I'd love to have it.

#458 Artificiality

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Posted 28 April 2013 - 11:20 PM

From the looks of it there should be some spots open. 32 out of 40 have payed, I want to get this going, I'm growing impatient.

#459 sunshinefrost

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Posted 29 April 2013 - 03:38 AM

From the looks of it there should be some spots open. 32 out of 40 have payed, I want to get this going, I'm growing impatient.


i agree that it woulb be nice to press a button and ... voilà ! stuff magically happens.

#460 ScienceGuy

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Posted 29 April 2013 - 05:03 AM

UPDATE:

Hi Everyone,

To confirm, I just received from SUNSHINEFROST payment of US$4,360 via PAYPAL; which equates to 32 PARTICIPANTS at 2.5 GRAMS per each participant = 80 GRAMS of NSI-189 :)

A huge thank you to SUNSHINEFROST for his significant time spent organizing the collection of funds from the participants in this group buy ;)

I will now proceed with immediately placing the order for custom synthesis of 200 GRAMS of NSI-189 (>=99.9% PURITY) with the respective CUSTOM SYNTHESIS LABORATORY :)


Please kindly note that this does not mean that this particular group buy is CLOSED; in that further individuals who wish to join in can do so... Basically, we wanted to get the ball rolling regards the custom synthesis, given it will take about 5 WEEKS to complete... and hence, I will be providing the funds to cover the other 120 GRAMS of NSI-189 for the purposes of allowing the order for 200 GRAMS to be placed and to achieve the necessary 200 GRAMS pricing of US$54.50 / GRAM... In short, we will be leaving it open for further participants to join in, and so anyone wishing to do so please kindly proceed with providing your US$136.25 for 2.5 GRAMS NSI-189 to SUNSHINEFROST. There is room for EIGHT more participants (only); and it will be first-come-first-served basis, in that the first EIGHT people to provide payment to SUNSHINEFROST will secure the remaining 8 slots... then we will have reached the maximum 40 participants and the group buy will be CLOSED. ;)

Edited by ScienceGuy, 03 May 2013 - 05:00 AM.

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#461 ScienceGuy

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Posted 29 April 2013 - 05:11 AM

Looks like the NSI-189 group buy is closed. I didn't notice what you all were up to, due to testing Sunifiram.

But if there's a spot open, I'd love to have it.


From the looks of it there should be some spots open. 32 out of 40 have payed, I want to get this going, I'm growing impatient.


Hey Sunshinefrost, can we have an update on what's going on?

You better not have legged it with our cash! (half-joking, half-concerned)


Well now that ScienceGuy is back it hopefully wont be too long before the order is placed! Ahhh my god I'm so excited for this chem. Having suffered from severe depression in the past, and experiencing persistent memory problems, I will most likely be a super-responder :-) Keep us updated Frosty!


Please kindly see today's UPDATE which I have just posted :)

#462 Artificiality

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Posted 29 April 2013 - 07:41 AM

From the looks of it there should be some spots open. 32 out of 40 have payed, I want to get this going, I'm growing impatient.


i agree that it woulb be nice to press a button and ... voilà ! stuff magically happens.


If my comment came off as directed towards you, I apologize. You've been working hard to get this project started, and I appreciate all you've done, especially considering that you pretty much took on, and organized this group buy. So thank you!
I was expressing annoyance with those who signed up for this and slowed it down by being unresponsive and/or not paying.

#463 Xenix

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Posted 29 April 2013 - 08:22 AM

UPDATE:

Hi Everyone,

To confirm, I just received from SUNSHINEFROST payment of US$4,360 via PAYPAL; which equates to 32 PARTICIPANTS at 2.5 GRAMS per each participant = 80 GRAMS of NSI-189 :)

A huge thank you to SUNSHINEFROST for his significant time spent organizing the collection of funds from the participants in this group buy ;)

I will now proceed with immediately placing the order for custom synthesis of 200 GRAMS of NSI-189 (>=99.9% PURITY) with SYNTHEX :)


Please kindly note that this does not mean that this particular group buy is CLOSED; in that further individuals who wish to join in can do so... Basically, we wanted to get the ball rolling regards the custom synthesis, given it will take about 5 WEEKS to complete... and hence, I will be providing the funds to cover the other 120 GRAMS of NSI-189 for the purposes of allowing the order for 200 GRAMS to be placed and to achieve the necessary 200 GRAMS pricing of US$54.50 / GRAM... In short, we will be leaving it open for further participants to join in, and so anyone wishing to do so please kindly proceed with providing your US$136.25 for 2.5 GRAMS NSI-189 to SUNSHINEFROST. There is room for EIGHT more participants (only); and it will be first-come-first-served basis, in that the first EIGHT people to provide payment to SUNSHINEFROST will secure the remaining 8 slots... then we will have reached the maximum 40 participants and the group buy will be CLOSED. ;)


So what will you be doing with the remaining 100 grams? mega-dosing? :P

#464 Izan

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Posted 29 April 2013 - 10:09 AM

sunshinefrost AND scienceguy, i salute you both gentlemen.
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#465 Werper

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Posted 29 April 2013 - 01:22 PM

A damn good way to start off the week, thank you both!

#466 MizTen

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Posted 29 April 2013 - 02:07 PM

Well this is great! Many thanks to those who made this happen. I've PMd sunshinefrost for payment details, hopefully I can do this.

Sent from my GT-N8013 using Tapatalk HD

#467 daouda

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Posted 29 April 2013 - 06:06 PM

In short, we will be leaving it open for further participants to join in, and so anyone wishing to do so please kindly proceed with providing your US$136.25 for 2.5 GRAMS NSI-189 to SUNSHINEFROST. There is room for EIGHT more participants (only); and it will be first-come-first-served basis, in that the first EIGHT people to provide payment to SUNSHINEFROST will secure the remaining 8 slots... then we will have reached the maximum 40 participants and the group buy will be CLOSED. ;)


Thank you scienceguy for putting this clearly (and publicly!!). It really didn"t make much sense to suddendly operate "underground" via PM only when everything we intended to do was very clear from the previous posts anyway, and I think it really didnt make for an efficient operation. I'm sure we'll even get to 40 pretty fast now thanks to this simple, clear post.
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#468 Rior

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Posted 29 April 2013 - 07:10 PM

Psyched for this to go through. Very happy it's advancing.

#469 sparkk51

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Posted 29 April 2013 - 09:04 PM

How much should 100 grams last you ScienceGuy?

Is the amount each participant is receiving less than what was given to clinical trial patients?

#470 daouda

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Posted 29 April 2013 - 09:13 PM

Sparkk, the anwser is explicitly given just a few pages back in this thread... But since some other ppl might also be extremely lazy :
http://clinicaltrial...how/NCT01520649
Clinical trial : 3 cohorts given 40mg once to thrice per day for 28 days. Total 1120mg, 2240mg or 3360mg per cohort. We're getting 2500mg per person. Voilà.

Edited by daouda, 29 April 2013 - 09:14 PM.

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#471 sparkk51

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Posted 30 April 2013 - 02:03 AM

Sparkk, the anwser is explicitly given just a few pages back in this thread... But since some other ppl might also be extremely lazy :
http://clinicaltrial...how/NCT01520649
Clinical trial : 3 cohorts given 40mg once to thrice per day for 28 days. Total 1120mg, 2240mg or 3360mg per cohort. We're getting 2500mg per person. Voilà.


Thanks, your link is actually on page 8 which I found using ctrl+f. I did in fact sift through the pages looking for the appropriate link but couldnt find it myself. I Wouldn't call myself extremely lazy but I gave you a thumbs up anyway.

#472 Reformed-Redan

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Posted 30 April 2013 - 02:09 AM

Whats the optimal dose to achieve the desired effects with 2.5g? Sounds like a calculus problem.

#473 daouda

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Posted 30 April 2013 - 02:24 AM

In short, we will be leaving it open for further participants to join in, and so anyone wishing to do so please kindly proceed with providing your US$136.25 for 2.5 GRAMS NSI-189 to SUNSHINEFROST. There is room for EIGHT more participants (only); and it will be first-come-first-served basis, in that the first EIGHT people to provide payment to SUNSHINEFROST will secure the remaining 8 slots... then we will have reached the maximum 40 participants and the group buy will be CLOSED. ;)


Thank you scienceguy for putting this clearly (and publicly!!). It really didn"t make much sense to suddendly operate "underground" via PM only when everything we intended to do was very clear from the previous posts anyway, and I think it really didnt make for an efficient operation. I'm sure we'll even get to 40 pretty fast now thanks to this simple, clear post.

Hmm I've been downvoted twice for this? I realize it may have sounded like an attack against our dear buddy sunshinefrost which I definitely not intended to be... My point is that for an effective group buy communication is paramount and with the 2 PM PER DAY LIMIT for non-members keeping it "PM-only" is DEFINITELY counterproductive, and PLUS did not make any sense nor serve any purpose whatsoever when we had clearly exposed our project publicly before AND the actual payitsquare link was kept private anyway. I said this directly to Sunshinefrost already so it's not like I'm badmouthing him publicly behind his back... Further group buys are going to take place and I think we are learning in this process and the next ones are gonna flow more and more smoothly. I learned from my first one recently that transparency of every step to every participant is primordial to avoid doubts and frustrations (we all are sending out money to strangers over the internet!). Had we not been "forbidden" to update the progression publicly. Artificiality and OpaqueMind would not have posted what they have posted above (a very natural feeling). This group buy is definitely going to be a success (it pretty much is already thanks to scienceguy and sunshinefrost) but we can definitely still learn from the experience and improve the process for the next projects.
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#474 Werper

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Posted 30 April 2013 - 03:15 AM

Agree Daouda, good post.

#475 MetaMind

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Posted 30 April 2013 - 06:19 AM

Word


#476 Posthuman

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Posted 30 April 2013 - 07:25 AM

I wish to participate in this group! I searched for "enhance your memory" on Pay It Square, but to no avail. To whom should I send the amount of US$136.25 between ScienceGuy or Sunshinefrost, and how/at what Paypal email?

#477 Izan

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Posted 30 April 2013 - 10:05 AM

I wish to participate in this group! I searched for "enhance your memory" on Pay It Square, but to no avail. To whom should I send the amount of US$136.25 between ScienceGuy or Sunshinefrost, and how/at what Paypal email?

you should send sunshinefrost a pm. it's really not that hard to figure this out. ;)

#478 Posthuman

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Posted 30 April 2013 - 01:26 PM

I wish to participate in this group! I searched for "enhance your memory" on Pay It Square, but to no avail. To whom should I send the amount of US$136.25 between ScienceGuy or Sunshinefrost, and how/at what Paypal email?

you should send sunshinefrost a pm. it's really not that hard to figure this out. ;)


Yeah I PM them both just after I made my wish to participate public! Thanks anyways.

#479 Xenix

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Posted 30 April 2013 - 01:39 PM

Whats the optimal dose to achieve the desired effects with 2.5g? Sounds like a calculus problem.


Personally I would stick with 40mg/day for 2 months than 80mg for one month. But that's just me. I can see some people getting impatient and doing huge doses in an attempt to see effects faster... but that's up to them.

It's definitely going to suck if *just as* the effects from NSI become amazing, the supply runs out... but then again it's not an SSRI - so who knows how long it will take for the drug to fully "kick in" and increase hippocampal size while creating a noticeable difference in cognition/memory. *shrug* time will tell.

edit: more is never enough :P

Edited by Xenix, 30 April 2013 - 01:40 PM.


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#480 Web

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Posted 30 April 2013 - 02:46 PM

I've perused this thread and forgive me if I missed something relevant to my questions, but I'm wondering if anyone could help shed some light on the following concerns (these may seem clear to many but alas, I'm more of a music/creative writing type than scientific and just now discovering nootropics):

1. Do we know if there is any effect on mood, or any psychological/emotional effect? (I'm more worried about negative effects than positive effects.)

2. Do we know if there is any risk of addiction?

3 Do we know if there is any withdrawal, or what happens when one takes this for a while and then abruptly stops?

Again, I have essentially no knowledge of chemistry or the mechanisms in the brain that would be affected in order for these conditions to arise. Forgive me if this is basic stuff. Also, it may be the case that nobody really knows the answers to any of this, and that solving these questions is part of the experimentation we're doing with the group buy. In that case sorry for jumping the gun.

Thanks guys.

Ah, one more thing. I think this was dealt with but I can't find it in the thread: how long does this stuff keep for?

Edited by Web, 30 April 2013 - 02:50 PM.






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