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NSI-189

nsi-189

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#1951 VERITAS INCORRUPTUS

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Posted 16 May 2014 - 04:55 PM

^^^

Jefferson,

^^^

Best simply contact drspaceman to get his address and send it off.  Hopefully he will relay the time frame he will try to accommodate testing if you do so. He is in NY so easy enough to send off for quick receipt.

 

As well, perhaps contact SG and ask for the lab's contact info that tested his batch if you want a definitive assay and/or are willing to bear expense or if someone notes they will do so if this is instituted.

 

A simple execution of some valid testing would be more rational than going roundabout on all this without any more definitive answers as to the authenticity of the material.

 

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#1952 Flex

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Posted 17 May 2014 - 06:44 AM

Voilá

 

NSI 189
 
As said, tested with: H1NMR (300MHz)
 
Hope there is someone who can interpret- and say anything about it.

 

Edit: forgot to mention that I recieved it as a .docx with a size of 2.61 MB.

(with nothing than the sole Image)

Couldn´t upload because of the size, so therefore converted it to a .jpg


Edited by Flex, 17 May 2014 - 07:11 AM.

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#1953 Flex

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Posted 17 May 2014 - 07:16 AM

Btw: He will re-run the test next week with a different solvent due to solubility issues.


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#1954 world33

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Posted 17 May 2014 - 12:09 PM

I contacted the Chinese supplier in alibaba.com and they sell min 100g for 1,000 dollars. How many daily doses can you get with 100gr? Let's say 40mg per day as a conservative approach. Then 100g gives you 2,500 daily doses of 40mg at 40 cents each.

Is it reasonably priced?

Are these Chinese suppliers trustworthy?

When they say that the product is for research only does that mean that they cannot assure the purity for human consumption or just trying to cover their ass for legal reasons considering the early stage of the research on this compound?

 


Edited by world33, 17 May 2014 - 12:22 PM.


#1955 telight

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Posted 17 May 2014 - 01:16 PM

Voilá

 

 
 
As said, tested with: H1NMR (300MHz)
 
Hope there is someone who can interpret- and say anything about it.

 

Edit: forgot to mention that I recieved it as a .docx with a size of 2.61 MB.

(with nothing than the sole Image)

Couldn´t upload because of the size, so therefore converted it to a .jpg

 

Comparing the drawn image to that structure of the real NSi-189, it is exactly same. If the peaks correctly determined the image that is drawn then the sample analyzed is in fact real NSI-189.


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#1956 verticalVagabond

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Posted 17 May 2014 - 04:05 PM

 

Voilá

 

 
 
As said, tested with: H1NMR (300MHz)
 
Hope there is someone who can interpret- and say anything about it.

 

Edit: forgot to mention that I recieved it as a .docx with a size of 2.61 MB.

(with nothing than the sole Image)

Couldn´t upload because of the size, so therefore converted it to a .jpg

 

Comparing the drawn image to that structure of the real NSi-189, it is exactly same. If the peaks correctly determined the image that is drawn then the sample analyzed is in fact real NSI-189.

 

 

Boom goes the dynamite.

Now can we please stop with the neurotic rumors? Some of us have a lot of healing to do.



#1957 golden1

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Posted 17 May 2014 - 08:39 PM

 

 

Voilá

 

 
 
As said, tested with: H1NMR (300MHz)
 
Hope there is someone who can interpret- and say anything about it.

 

Edit: forgot to mention that I recieved it as a .docx with a size of 2.61 MB.

(with nothing than the sole Image)

Couldn´t upload because of the size, so therefore converted it to a .jpg

 

Comparing the drawn image to that structure of the real NSi-189, it is exactly same. If the peaks correctly determined the image that is drawn then the sample analyzed is in fact real NSI-189.

 

 

Boom goes the dynamite.

Now can we please stop with the neurotic rumors? Some of us have a lot of healing to do.

 

wow very quick to dismiss lol. Do you know if the molecule has anything to do with the NMR data or if it is just a drawing for reference? hahaa



#1958 Perek

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Posted 17 May 2014 - 09:45 PM

Well, NSI-189 got some real attention in the last 6-12 months. A drug that just passed phase 1b and statistically got less than 1% chance to make it to the market. I don't know of many here reporting they had substantial benefit. A handful? Few dozen? I know it's hard to tell. Most people wont record and out their experience. I tried few grams of SG and 1gr Nyles7 over the last 3-4 months. Went slow on only 20mg a day due to the fact that I didn't know shit about what I was taking and when I tried to up the dose I felt increased anxiety. I GUESS Nyles was better for me, depression/anxiety wise. The taste of Nyles7 was really ok, SG's was very chemical. But NSI didn't give me much so far, if anything. I love to test new substances and I want to. Need to. But I am sorry to see so many naive dealers and wheelers around here with so many members very willing and able to try it. and I don't trust anyone in this tread. Why? Cause no delivery, just bullshit for months. Like another group buy tread I followed. A drug dealer from the street with basic computer knowledge would make it better. Then someone could say, "Hey you can't make a profit...it's patented blabla". Off course, e.g. thats why Mr Kaminski (googletarian)? couldn't take any of the 20.000 Euros paid? by VLK to heat up his below zero apartment.... Yeah, take a line. Vegan, non profit Columbian indian heritage resque fund super snort. Hellaluja.
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#1959 Perek

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Posted 17 May 2014 - 09:55 PM

My god, I just saw that I got like MINUS 13 with my posts here. Haha....

 

I am just frank. Sorry guys...

 

 


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#1960 Perek

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Posted 17 May 2014 - 10:19 PM

Sorry it was -17, haha...

 

 

I get fed up with this lack of brains and thereby getting a bit agitated?

 

Possibly. But really, I find this forum a bit frustrating.

 

Maybe I need to  turn to the Alibaba forum instead.

 

Is it safe ?


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#1961 MizTen

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Posted 17 May 2014 - 10:24 PM

I have purchased two separate batches at 2 different times from vlk, both were the same in taste, consistency, appearance and efffects. Also received 1 batch from another highly regarded and credible source (on longecity) and found that to also be exactly the same in above noted features. Vlk deserves some kind of award for ethics, vision, persistence, courage, and reliability, really.

I also tend to agree with PWAIN's post here: http://www.longecity...ndpost&p=662702 that there's something odd about some of the newer commenters.

As far as neurotoxicity, I really, really doubt it. But as with any new drug, prescription or not, it should be taken alone until effects (and potential side effects) are evident. Each person may have a unique response to the same drug. I had some mild and short lasting non-problematic effects on an area of my hand/wrist that had considerable pre-existing nerve damage. At the beginning of each of my 3 trials, there were some mild headaches, hunger, and "whooshing" (for lack of a better word) sensations in my head, also some sleepiness. I am now beginning to suspect those symptoms are actually evidence of neurogenesis.

This drug, for me, is very adjustable, very easy to work with in terms of using other modalities to enhance neurogenesis and healing. Generally, I take between 30-40 mg two to three times a day. I will be stopping in a couple of days, and hope the same magic happens upon cessation as it has in the past. Although the NSI-189 has a positive effect for me while I'm taking it, the profound changes are more apparent after stopping. I think the off cycles could go on as long as six months or more for me. I cannot imagine that this could be addictive. Of course, I want to have it available (for the rest of my life), but the strongest and most positive effects are most evident when stopping.

Yes, I have dabbled in other neurotropics, some while taking NSI-189. Some of those have been helpful. But I am very convinced that the NSI-189 was the key to my healing. Possibly C-6o has helped, but I wasn't taking it on my first NSI189 trial, which had considerable positive effects.

Improvements:
Driving - increased responsiveness, reduced anxiety, increased navigational memory, better judgement overall
Cognition - increased reading comprehension and information retention, remembering personal agendas, lists, etc, more focus
Social/Relational - more patient, more understanding, better follow-through, more assertive
Psychological- less reactive, better mood, dream recall (finally after 6 years of none!), hope for the future, increased libido, better able to start and maintain good habits, much less negative mental chatter, much better results from exercise, meditation, creative activities, mindfullness practice.

The overall external conditions of my life have not noticeably improved, but are much easier to deal with now. Thus actions to improve that part of my life will likely be more effective, as I can stick with my plans for improvement and be more able to respond to opportunities for positive change. My brain and emotional self just work a whole lot better and that can easily b built upon over time if you are doing the right things.

Beats things like adderall, ssri, benzos, etc by a long shot. Enhances things like exercise, meditation, binaural beats, other supplements with neurotropic benefits, such as DHA, lithium orotate, pregenolone, etc.

As far as obtaining it via grey market, as we are doing here, I have some of the same concerns as others about purity from new suppliers and am also concerned about adulteration with non-toxic additives to increase weight.


Edited by MizTen, 17 May 2014 - 10:28 PM.

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#1962 Perek

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Posted 17 May 2014 - 11:09 PM

30 grams, hmm...$1000+ and you could not afford to  give your trusted friend a  tip for changing your life?

 

Sweet.



#1963 Perek

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Posted 17 May 2014 - 11:15 PM

I am really glad to know NSI made such a difference for you!

 

You did post about it before several times and I think your experience is the very reason why I am trying it myself.

 

I was hoping there was many more or even a handful like yours.

 

Never mind, there are so many possibilities out there and with TRULY personalized medicine things will change.

 


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#1964 gnappi

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Posted 17 May 2014 - 11:23 PM

NSI-189 2.5g  for $99,99:

http://nutraction.com/shop/nsi-189/


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#1965 Perek

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Posted 17 May 2014 - 11:34 PM

Again...hmm.

 

 

Looking at my profile and just got - negs.- 

 

For telling the truth? 

 

I would rather have comments.

 

It would serve the community better.

 

 

If you make sense.

 

 

 

 

 

 

 

 

 


And Gnappi in Brazil is in for a backorder....

 

 

Are there any moderators around at all????



#1966 Jbac

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Posted 17 May 2014 - 11:49 PM

Does NSI degrade rapidly when exposed to air? Mine was exposed to air at room temperature for about a week. I keep it in the refrigerator now and take 100 mg per day. Still not feeling anything after a few weeks.

#1967 Perek

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Posted 17 May 2014 - 11:58 PM

Dry "stable"  powder doesn't oxidise quickly.

Hang in there. Did you try sublingual?

What batch?

 

 



#1968 Jbac

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Posted 18 May 2014 - 12:08 AM

Nyles batch
The taste hasn't changed but the powder has gotten hard and clumpy
Sublingual is certainly more bioavailable and allows me to 'feel it' at a lower dose, but I still don't get benefits. The only sign of activity I get is a fuzzy feeling in the brain for 10 minutes after a dose.
Maybe I'll switch to 100 mg sublingual, or try a different vendor after I finish my 5 g.

#1969 swolo

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Posted 18 May 2014 - 05:22 AM

Voilá

 

 
 
As said, tested with: H1NMR (300MHz)
 
Hope there is someone who can interpret- and say anything about it.

 

Edit: forgot to mention that I recieved it as a .docx with a size of 2.61 MB.

(with nothing than the sole Image)

Couldn´t upload because of the size, so therefore converted it to a .jpg

Ok, that shows it's NSI-189. What is suspicious?

 

Can you please ask joeyo to post in this thread, just to sort of confirm he exists? "Hi" would suffice, or just the letter "h" if he can manage.


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#1970 Flex

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Posted 18 May 2014 - 08:53 AM

Dont know whether I should answer this...

How about asking the other members if he exist ?

or even going to the participants thread, where he made the (free!)offer ?

or at least typing his name in the search bar ?


Edited by Flex, 18 May 2014 - 09:10 AM.

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#1971 arcticjoe

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Posted 18 May 2014 - 09:07 AM

I have been taking VLK's NSI for nearly 2 months at ~5mg per day and it has made dramatic changes to how I feel. I've tried larger doses but I suspect the dose response may have a U shaped curve as larger doses were less effective and caused more side effects like headaches or foggy feeling in the brain. I also discovered that NSI does not mix well with modafinil and gingko, modafinil + nsi seems to make me crash really hard and feel physically unwell, whereas gingko + nsi gives me a pretty severe migraines. I also do not recommend taking it in the evening as it seems to interfere with the sleep cycle somewhat, I take it once in the morning and that does the job for the whole day.

For me NSI has really ramped up my confidence and slowly eroded any old fears and anxieties I've had. I have become far more aggressive at work, to a point where it started getting me into trouble with my senior managers - but I suspect this reduction of fear has made me speak without hesitation, as my new general feel is "if what I am saying is true, the I dont give a sh*t if its going to upset you".

My memory is still shoddy, but I find it bothers me a lot less - I am happier and much more resilient to stress than before taking NSI.


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#1972 Hungry Hippo

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Posted 18 May 2014 - 11:06 AM

The thought of a lawsuit never crossed my mind and I have no intention of pursuing one. Fortunately, the neuropathy seems to be slowly going away. The shooting pain in my pelvis is almost completely gone. Mostly, the symptoms have morphed from burning sensations to itching on my ankles and wrists. Hopefully this will be relegated to just a bad memory in a few months, but who knows.

 

Look, maybe I am just unlucky, and this is one of those very rare one out of a hundred/thousand side-effects that you see when you look at the fine print of many psychiatric drugs. Or, this is not NSI-189, but something else, and it’s more dangerous and more toxic. Based on the extremely limited information I have about VLK and who produced his drug, as well as the limited information about NSI-189 as produced by Neuralstem, taken together with this violent reaction I had, I don’t know which is more likely. At this point I’m not playing the blame game, as I recognize the inherent risk the buyer assumes in circumstances like this.

 

But doesn’t it concern anyone else taking it that you’re potentially ingesting a substance that could cause serious side-effects like what I experienced? At the least, I would encourage people in on this buy to stop taking it until we have more evidence through independent testing that this is the drug advertised. This is a very reasonable precaution.

 

How many people have taken VLK’s batch at this point? How large is this sample? Has anyone else noticed bad side-effects? These are basic questions that should be answered and catalogued on the site somewhere or something. In an ideal world, everyone in on this buy and any longecity buys should be sent an anonymous questionnaire or survey after taking any experimental drug, detailing their experiences, for future reference.

 

I have 6g of this stuff that I’m not taking or intend to take again, obviously. I will gladly mail portions of it out to drspaceman, or anyone who has the capability to test it.

 

For the record, I had adverse effects like you describe when i started up with different meds, like Wellbutrin, Selegiline, Tianeptine. The first two came from a pharmacy. I combined NSI with Wellbutrin and the combination was not so nice as taking NSI alone. I got pain in muscles, joints, pelvis and tendon in the knee (very nasty, but this occurs strangly enough with more AD's).



#1973 Hungry Hippo

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Posted 18 May 2014 - 12:16 PM

I contacted the Chinese supplier in alibaba.com and they sell min 100g for 1,000 dollars. How many daily doses can you get with 100gr? Let's say 40mg per day as a conservative approach. Then 100g gives you 2,500 daily doses of 40mg at 40 cents each.

Is it reasonably priced?

Are these Chinese suppliers trustworthy?

When they say that the product is for research only does that mean that they cannot assure the purity for human consumption or just trying to cover their ass for legal reasons considering the early stage of the research on this compound?

 

 

That's a great price. Interesting. Some of the Chinese suppliers are trustworthy, but all of them? (The Chinese have a proverb that goes something like this: you can trust all but one. I think it's genious...)

 

I do know that the standards for export are much higer than for production for use within China. The governement can silence bad news within their borders but not outside the borders of China. A companie gets severe punished if they sell crap to foreign countries.

 

As long as a compound is a research chemical it's not for human or animal use. VLK, Nyles have to tell you this too (and I know Nyles is). It means that they can't take any responsibility for what you're doing with it and when they say it's for human use or is good for your health, they make strictly speaken illegal claims. This goes for walnuts too. If you claim that it has benefits for your health, cures sickness, it's medication. And you can't sell medication if you're not licensed.

 

And that is exactly what happened  :)

 

http://www.fda.gov/i...s/ucm202825.htm


Edited by Hungry Hippo, 18 May 2014 - 12:19 PM.


#1974 world33

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Posted 18 May 2014 - 12:48 PM

Thanks Hippo for your reply. I actually contacted the alibaba.com seller to see if they can half the minimum order quantity to 50gr for 500$. I have not read the entire 65 pages of this post but in your opinion is this new compound going to have any positive effect on depression/anxiety levels provided it is genuine? Is it stronger than lion's mane when it comes to neurogenesis? Before embarking in such an investment I would like to make sure it will have some effects. Anyone interested in splitting the quantity/cost in half (i.e. 25 grams each) ? Does anyone knows why nyles7 is not selling this compound anymore on eBay?


Edited by world33, 18 May 2014 - 12:51 PM.


#1975 Nattzor

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Posted 18 May 2014 - 01:24 PM

It's way stronger than lion's mane when it comes to neurogenesis, atleast in the hippocampus. If it's legit it should help with depression, although the trials are too early for anything conclusive. They'll publish phase 1b in June or July, can't remember atm.



#1976 pro-v

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Posted 18 May 2014 - 01:37 PM

I have some from nyles and some from vlk and can tell you with certainty that they have noticeably different effects. The batch from VLK gave me massive headaches, which is what has happened anytime I ever took noopept or any of the racetams. The batch from nyles had very few side effects other than some slight edginess and feeling much better after a few weeks.
My results really don't bring anything conclusive to the table but I did want to put them out there.
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#1977 chemicalambrosia

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Posted 18 May 2014 - 03:27 PM

Thanks Hippo for your reply. I actually contacted the alibaba.com seller to see if they can half the minimum order quantity to 50gr for 500$. I have not read the entire 65 pages of this post but in your opinion is this new compound going to have any positive effect on depression/anxiety levels provided it is genuine? Is it stronger than lion's mane when it comes to neurogenesis? Before embarking in such an investment I would like to make sure it will have some effects. Anyone interested in splitting the quantity/cost in half (i.e. 25 grams each) ? Does anyone knows why nyles7 is not selling this compound anymore on eBay?

 

I think its a pretty safe bet that you aren't going to legitimately get this compound custom synthesized for $500. Also, randomly picking chemical suppliers off of the internet is only a strategy that works if you are willing to get product tested and are willing to get scammed multiple times in the process. You are much better off finding a trusted supplier that comes recommended by someone trustworthy. FYI, I don't order custom synthesized chemicals, so I can't help you further.



#1978 foreseason

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Posted 18 May 2014 - 03:57 PM

Sourcing a supplier via Alibaba is not as easy as I think you're hoping it is. It certainly can work, but negotiating with manufacturers halfway across the world is no easy task. You can and often will get screwed whether it's intentional or not. The language barrier alone can cause major complications.

A decent intoruction to using alibaba and what you can expect

http://www.abetterle...t-from-alibaba/

#1979 drg

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Posted 19 May 2014 - 03:51 AM

Does anyone knows why nyles7 is not selling this compound anymore on eBay?

He isn't allowed to sell it on ebay anymore. Not sure the exact reason but he had to take the listing down.



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#1980 drg

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Posted 19 May 2014 - 03:51 AM

Does anyone knows why nyles7 is not selling this compound anymore on eBay?

He isn't allowed to sell it on ebay anymore. Not sure the exact reason but he had to take the listing down.







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