I wanted to mention two things of interest in this thread:
First and foremost, I have created an "NSI-189 BENEFITS/DETRIMENTS Poll that can be found here. It would be great if those who have experienced NSI here would help by posting there. As of now, I'm trying to have the thread moved to the "Brain Health" section of this forum, as it would be more appropriate here.
Second,
I will be commencing my trial of NSI-189. It is ScienceGuy's original group buy NSI. I've been holding onto it for a little over a year now, not using it, waiting to see further results before I put my head into the trial myself. That said: It's worth regarding the molecule's stability (has it degraded over the last year?).
My plans are this so far:
30mg NSI-189 BID, in the morning and at night, ORALLY (not sublingual), on an empty stomach.
25mg Zoloft (A very small, dose, but very helpful for me)
Fish oil at night (purposes of helping produce myelin while sleeping for any new neurons)
Creatine at 5-10g/day
Heavy exercise regimen (I've been on a heavy regimen for about 2-3 months now)
ZMA supplement (Zinc, Magnesium and B vitamins) at night
Occasional GHB use for aiding in sleep (perhaps 3 nights a week. Muscle recovery, as well as generally higher quality sleep as I tend to have poor sleep quality)
Yes, I know I have many confounding variables in my NSI experiment. I acknowledge that. I'm doing it primarily for myself though, obviously, and plan on sharing my experiences solely for the purposes of others who may find interest in it.
My background: Multiple concussions from soccer. Multiple. Reduced capacity for working memory, reduced capacity for storage of long-term memory, reduced verbal fluency, reduced creativity, almost -zero- sense of smell anymore, mild, occasional depersonalization. Essentially, I could use some brain growth IMO.
So far: 2 days in I can at least note the immediate effects I experience, which mimic those I experienced over the 4 day trial I gave NSI a year ago. The first thing I notice is mental and physical stimulation. It is dramatic in comparison to my usually-lethargic self. It comes on within 45 minutes to an hour after dosing, and almost feels like a mild amphetamine high. (I'll be driving and music feels enhanced, my eyes are darting around everywhere heavily analyzing everything.) I would so far state that it is certainly not placebo, as it is a dramatic change in headspace. I could be mentally enhancing the effects due to excitement after noticing a difference, however there is certainly a difference in headspace nonetheless. So far my verbal fluency has already picked up a little bit, and my racing thoughts have slowed down a little as well. This is too soon for this to be a result of new neurons/neurogenesis, so I'm naturally assuming that there is some other pharmacological mechanism happening that has enhanced my thoughts so far.
I guess that's all so far, will update as I go along. I'll note that a year ago I did try combining NSI with a 5mL dose of cerebrolysin, and it was a terrible, head-foggy combination.
Edit: Just need to edit this once more to say HOLY SHIT does NSI give me a massive spike in energy. I had forgotten I had taken it, then here I am about an hour later flying with energy wondering why. Then I remembered the NSI. Jesus. It's damned euphoric honestly. I know this is a very atypical response to the NSI, and I don't expect the effect to last longer than 4-6 days....but it's nice while it's here.
Edited by Rior, 09 July 2014 - 10:41 PM.