You have to give NSI-189 a full 28 days of dosing to get its benefits.
Anyone getting effects from the first few days is simply the placebo effect. Though, i could be wrong but this is my personal experience from multiple cycles.
I keep a diary of when NSI-189 kicks in, and its obvious. Its always around the day 22 mark.
This is not always the case, but everyone trying it should persist for at least month, I remember a member (maybe Major Legend?) that had its first effects after one and a half months. I got manic with my first NSI-189 dose in a way I never expected, it had the same effect (to a lower degree) for the following 3-4 days until it subsided to a more natural positive feeling. I have a pm from a guy in UK with the exact same experience. He said that possibly is going to post it in the future, so he maybe do so if/when he read this. I do not think there is another experience like his posted on line, extreme good feelings (close to manic) I ll maybe contact him to see if its OK to copy/paste his pm.