Hello long time lurker here, and I figured it was about time I contributed.
This is my experience after a month of NSI-189 20-30mg free base-sublingual
Curren Daily Stack :
Lion's Mane Mushroom 1,500mg
Taurine 1000mg
L-Tyrosine 500mg
COD Liver Oil (3g of EPA/DHA)
B-Complex Vitamins
Ubiquinol 50mg
PQQ 20mg
CoQ10 100mg
Phosphatidyl Serine 150mg
Vitamin D-3 5,000IU (every two days)
Biotin 10,000mcg
Glutathione 500mg
Current Rxed Medication:
Venlafaxine (Effexor) 18.75mg (Currently tapering off from 75mg)
Bupropion (Wellbutrin XL) 150mg
I apologize in advance for my horrid grammar.
The NSI-189 was obtained from irc.bio and was taken before bed sublingualy . I'm currently taking this as an alternative to Effexor and depression as well as for the memory benefits. The first time I took it I felt the head pressure others had described and it wasn't subtle at all. The first week i coudln't really feel a difference. At work I was quite spacey and would get absorbed into my own little world and leave something behind or I would find myself stopping randomly and doing an awkward u-turn back to where from which I came to get the object I had completely forgotten about. Although I consider myself to be absent minded (unwarranted distraction of attention from the object of focus by irrelevant thoughts or environmental events) and i'd say that it made my disposition worse. At least initially.
The second week I started remembering things I had completely forgotten about that had happened years earlier, mostly comprised of very pleasant experiences. Although the memories weren't all good, I was able to shake them off pretty well. I also started to have pretty strange dreams which was an interesting side effect, at least they were entertaining. I also was/am able to recall them which to me was the really cool part. Sometimes after taking the NSI i would have trouble falling asleep which to me was indicative of the stimulating effects other users have reported.
The third/fourth week I was able to maintain focus a lot better and kept having insights on things that I was completely oblivious to, mostly the origin and meanings of words. My vocabulary I believe has gradually been improving and i've been experiencing a lot less of the "tip of my tongue" phenomena that happens to me when i'm talking to people which honestly felt great because I was able to better express myself. I've also been learning new words more often and more noticeably than before I started the NSI. This is also around the time where I noticed my episodic memory had improved quite a bit. I've been able to remember experiences with a greater amount of detail than I had previously i.e. images/sounds were more clear and I felt my brain was doing less guessing because it flowed so much smoother. I supposedly have a good memory, but I prefer the term image recognition because when I underwent some psychological testing they showed me 200 cards for 5 seconds each and then showed me a card with two images one was of one of the 200 images and the other was a random image and I scored a perfect 200. I believe NSI is allowing me to commit more to long term memory and in combination with my recognition skills has improved my perception. I also noticed that my mandarin got a lot better (when i practice conversations in my head) As far as mood goes I do feel better than I did before, and i'm more motivated to go out and do things, but because of the effexor withdrawal i find myself getting very pissed off at just about everyone and have a very short fuse which is very unlike myself.
Overall I'm very pleased with the results thus far and plan to continue NSI-189 and see how far I can take my memory and hope that it helps me through the Effexor withdrawal and allows me to live again.\
tl;dr
Noticeable improvement in memory, especially episodic memory. Has given me insights on the origin and meaning of words. Improved my Mandarin and recall of words/grammar. Mood has also improved. Effexor withdrawal sucks.
Edited by Entropyed, 24 October 2016 - 11:38 PM.