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NSI-189

nsi-189

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#4711 f099y

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Posted 07 December 2016 - 01:08 PM

Has anyone attempted using NSI for some sort of cognitive decline/impairment? Sorry it's a bit difficult to check through this thread :)



#4712 Mind_Paralysis

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Posted 07 December 2016 - 02:17 PM

Has anyone attempted using NSI for some sort of cognitive decline/impairment? Sorry it's a bit difficult to check through this thread :)

 

I have - if hippocampal atrophy from excessive cortisol-exposure counts.

 

I felt like a complete wreck cognitively, following my latest burnout-event - I had trouble speaking, trouble doing pretty much everything. At first, NSI-189 helped with every dimension!

 

As time went on though, it kept making me more and more tired, and more and more panicky, so I stopped using it.

 

 

I'm on it again though, since I've been feeling some depression once more - I've never been able to completely shrug my burnout though, because I NEVER get deep-sleep - meaning that the rest of my body is a complete mess - until I have Gabapentin, I cannot truly get the gains from NSI-189, it would seem.



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#4713 f099y

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Posted 07 December 2016 - 02:27 PM

 

Has anyone attempted using NSI for some sort of cognitive decline/impairment? Sorry it's a bit difficult to check through this thread :)

 

I have - if hippocampal atrophy from excessive cortisol-exposure counts.

 

I felt like a complete wreck cognitively, following my latest burnout-event - I had trouble speaking, trouble doing pretty much everything. At first, NSI-189 helped with every dimension!

 

As time went on though, it kept making me more and more tired, and more and more panicky, so I stopped using it.

 

 

I'm on it again though, since I've been feeling some depression once more - I've never been able to completely shrug my burnout though, because I NEVER get deep-sleep - meaning that the rest of my body is a complete mess - until I have Gabapentin, I cannot truly get the gains from NSI-189, it would seem.

 

 

Hmm yes as you've said we seem to really have many similar issues. I also don't seem to ever get proper sleep, going by the fact that i wake up tired nearly daily.

 

How is you're Atomoxetine trial going? I'm taking my last pill tomorrow, which will means i've been on it for 6 weeks at 80mg/day. Another disappointment!
 



#4714 linlin92

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Posted 07 December 2016 - 05:03 PM

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!


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#4715 bugsbunny

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Posted 07 December 2016 - 05:11 PM

Hello I have one question to chemical experts. I want to mix tianeptine and NSI-189 in a capsule is there any problem or interaction between the two substances in the capsule or is it ok?

 

@linlin92 

Are you female? I know a female person that has a little burnout and wants to regenerate. My idea was to use NSI-189 for that. Do you had any complications with 30mg NSI per day + 40mg Tianeptine?



#4716 TheCipher

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Posted 07 December 2016 - 05:36 PM

Does anyone here have knowledge regarding NSI's solubility, I would like to put it in a nasal spray, as that is easier than putting it under my tongue and waiting for an eternity!



#4717 Mind_Paralysis

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Posted 07 December 2016 - 08:03 PM

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!

 

Haven't tried it. Reason I'm interested in Gabapentin is because unlike the Benzo's and analogues, Gaba-P has been proven to increase the time in Deep sleep - Slow Wave Sleep - or Delta-Sleep if you like.

 

Most other Gabaergics just increase time in REM - meaning that even though I don't get a hang-over or it keeps me soundly asleep, I could still wake up tired as all heck... No deep sleep is in essence like sleep-deprivation.
 

For many others than me though, I'm sure it'll work just fine.



#4718 Legendary

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Posted 07 December 2016 - 08:07 PM

I can completely echo pheanix997's experience, to a T. I'm not so good at describing things/experiences, I'll square that on being an ENTJ personality type, but I'm doing my best to try and NSI-189 is really REALLY helping me confront, explore and work-out my emotional side. The first few days on NSI-189 were highly emotional, almost as if I was an extreme of my shadow version (ISFP) but that leveled out on day 3. This compound gave me the ability to work on all those emotions, discuss with my wife and fully realize them; thus letting them all go as a mere observation of reality. I can actually "live" in my childhood now, walk around my own neighborhood, explore, feel the breeze, etc. even while sitting here at my desk. I've NEVER had that before; I've had to rely on not so accurate state-in-time snapshots of my life and those snapshots were few and far between; thus I could never connect to my memories and childhood in teenage or adulthood. Honestly, this compound is amazing, life changer, and it showed me I probably have been living with depression for a long time and never even realized it. I historically have had such a strong will that I typically just "carried on," but I'm so invigorated to not need do that any longer, to actually live, have empathy, etc.

 

I do have a potential problem though; I just ran out of my Strangelove stock today and while I have more on the way (hopefully here any day) I'm not sure it's going to be tomorrow or even this week if it's held up somewhere (tracking stops on the 1st, leaving Europe); I also leave for vacation in a couple days. I'm only two weeks into dosing, so I'd hate to need stop for an entire week here (someone tell me that's a good thing!) but I can certainly tell the acuteness of this compound when I take it, and feel it waning a bit at the 20-hr half-life. If anyone within the US has some supply and is willing to overnight a small amount (1g?) I'll pay what's necessary; PM me.

 

 


Edited by Legendary, 07 December 2016 - 08:11 PM.


#4719 linlin92

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Posted 08 December 2016 - 02:59 AM

Hello I have one question to chemical experts. I want to mix tianeptine and NSI-189 in a capsule is there any problem or interaction between the two substances in the capsule or is it ok?

 

@linlin92 

Are you female? I know a female person that has a little burnout and wants to regenerate. My idea was to use NSI-189 for that. Do you had any complications with 30mg NSI per day + 40mg Tianeptine?

I fill 25mg NSI-189 with 12.5mg Tianeptine into a capsule so I take it with me on the go. I have been doing this for ages now and I haven't felt any bad interactions from it at all. Actually quite the opposite since I no longer get panicky or anxious on it. I think I am ready for twice a day dosage now.

Yes I am female heading towards mid 20's (yikes). I don't know about your friend, but are you sure the 'little burnout' and needing to 'regenerate' is the correct diagnosis? NSI-189 treatment is no joke, and she needs to be aware of side effects and how it affects the emotions and energy levels at the start of the treatment. Maybe try 12.5mg tianeptine once, then later twice a day and see how she responds to that first?

 

 

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!

 

Haven't tried it. Reason I'm interested in Gabapentin is because unlike the Benzo's and analogues, Gaba-P has been proven to increase the time in Deep sleep - Slow Wave Sleep - or Delta-Sleep if you like.

 

Most other Gabaergics just increase time in REM - meaning that even though I don't get a hang-over or it keeps me soundly asleep, I could still wake up tired as all heck... No deep sleep is in essence like sleep-deprivation.
 

For many others than me though, I'm sure it'll work just fine.

 

Oh, so you have problems falling asleep AND staying asleep? That is a tricky puzzle to solve. For me I just have problems drifting off into sleep. Once I get there then its all ok until the next morning. Thats why I use Etizolam because it has a very short half life of 3hrs and its a nice hynotic to slow racing thoughts that prevents me from sleeping in the first place.

 

Now that you mention it though I might give Lyrica a try and see if I get more delta sleep, especially if its the weekend and I plan to have a proper sleep in :')


Edited by linlin92, 08 December 2016 - 03:00 AM.


#4720 Heisenburger

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Posted 08 December 2016 - 05:46 AM

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!

 

Etizolam is probably the best sleep aid on the planet. Two milligrams will knock you out cold and give you eight to ten hours of deep, restorative sleep. Try it with some glycine, prazosin, and melatonin and you likely enjoy the best sleep you’ve ever had. Great thing about eti is that it takes at least several weeks to build up a tolerance to it, and when you do finally reach that point, all you have to do is lay off for a week or two and all the receptors reset themselves back to normal. It’s cheap, legal, and easily obtainable (although not nearly as easily as it was a couple of years ago). It is very hard to get addicted to, unlike the benzos. I took two milligrams almost every day for almost a year, quit cold turkey, and just shrugged off the worst of the withdrawal in about five or six days. In two weeks it was gone completely. And it’s nowhere near as miserable as benzo withdrawal. Right now I’d say it’s as close to the perfect sleep solution as currently exists. The half-life of the stuff is almost perfect, too—no walking around like a zombie the next day or falling asleep at work.


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#4721 MetaphasicSystems

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Posted 08 December 2016 - 02:35 PM

Oh god so much conflicting and confusing reports and ideas- I ALREADY struggle with fatigue, so if NSI increases that I don't know what I'll do. Same for anxiety. But what else is there?!? I've gone through so many options and lately none of them have even seemed to have any effect whatsoever. At least previously I experienced a honey moon period when I went onto a new anti-depressant.

And all the while my condition seems to deteriorate...


You stack it with other things, of course.

Tianeptine, Noopept, Magnesium-L-Threonate, Modafinil.


Don't be afraid to use it - just plan ahead before you take it - what issues that it will exacerbate initially, will you need other agents to counter?


You seem to have similar issues to me - I have a lot of anxiety and fatigue as well.

Well, then stack it with something which you KNOW decreases your anxiety significantly. And stack it with something that combats fatigue (I'd recommend Modafinil).


If you have not found something which significantly inhibits your anxiety, then you need to start a thread here - tell us all you can about yourself, and the potential mechanisms behind your problems - then we can figure something out for you - and then when you have anxiety under check, then you use NSI-189.


That's pretty much my stack right now.


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#4722 Hyperflux

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Posted 09 December 2016 - 06:09 AM

 

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!

 

Etizolam is probably the best sleep aid on the planet. Two milligrams will knock you out cold and give you eight to ten hours of deep, restorative sleep. Try it with some glycine, prazosin, and melatonin and you likely enjoy the best sleep you’ve ever had. Great thing about eti is that it takes at least several weeks to build up a tolerance to it, and when you do finally reach that point, all you have to do is lay off for a week or two and all the receptors reset themselves back to normal. It’s cheap, legal, and easily obtainable (although not nearly as easily as it was a couple of years ago). It is very hard to get addicted to, unlike the benzos. I took two milligrams almost every day for almost a year, quit cold turkey, and just shrugged off the worst of the withdrawal in about five or six days. In two weeks it was gone completely. And it’s nowhere near as miserable as benzo withdrawal. Right now I’d say it’s as close to the perfect sleep solution as currently exists. The half-life of the stuff is almost perfect, too—no walking around like a zombie the next day or falling asleep at work.

 

 

The research has shown that etizolam reduces REM sleep. I can't be bothered to pull up the papers right now but REM sleep reduction has been noted, and I remember an author saying that it may actually increase slow wave/deep sleep which is cool.

 

Anyway, my understanding is Strangelove is no longer offering NSI-189? So there's no way to get it?



#4723 IP3

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Posted 11 December 2016 - 04:44 AM

Be careful with etiazolam, it is just another benzodiazepine, Tolerance is an issue, also withdrawl, but paws (post-acute withdrawl-syndrome) are much worse. Not everyone develop paws, but thos who does regret using benzos.

 

I know that in US you can get prescription for ambien CR, zolpidem does not mess the sleep architecture but side effects are as above.


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#4724 Heisenburger

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Posted 11 December 2016 - 08:43 AM

The research has shown that etizolam reduces REM sleep. I can't be bothered to pull up the papers right now but REM sleep reduction has been noted, and I remember an author saying that it may actually increase slow wave/deep sleep which is cool.

 

Interesting. I’ve been using eti a lot lately (I go through repeating phases of long-term use followed by long-term discontinuation when tolerance sets in). About six months ago I suddenly stopped remembering my dreams. In the past six months, I have not had a single dream that I have any memory of the following day. I find it to be incredibly hard to get addicted to, BTW. I can use the stuff for months on end, stop cold turkey, and just go through a brief withdrawal period that only lasts a few days and consists mostly of insomnia and a little bit of absentmindedness—nothing even remotely close to the misery of Xanax withdrawal. That took me a month to get over and I was about as worthless as a bag of rocks the whole time. I had to fight as hard as I possibly could to focus on what I was doing when I was doing the laundry. Gah. Never again. I’ve taken Xanax since, but at sensible levels and never for more than a few days at a time.



#4725 Mind_Paralysis

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Posted 11 December 2016 - 03:10 PM

Be careful with etiazolam, it is just another benzodiazepine, Tolerance is an issue, also withdrawl, but paws (post-acute withdrawl-syndrome) are much worse. Not everyone develop paws, but thos who does regret using benzos.

 

I know that in US you can get prescription for ambien CR, zolpidem does not mess the sleep architecture but side effects are as above.

 

That depends - I've uncovered a post on ADD-forums with tons of other SCT-ers discussing their sleep issues - they are ALL earily similar to my own... and it appears to be the RULE rather than the exception, that SCT-ers have some sort of... ABNORMALITY in their sleep structure...

There appears to be more similarities to Narcolepsy than previously considered.

 

90% of EVERY SCT-er has non-restful sleep - or alternating non-restful sleep - our architecture seems to drift far, far easier APART than for neurotypicals.

 

 

Reviewing my own issues with sleep, I realize I've actually had alternating levels of non-restful sleep for TWO DECADES - the burnout just exarcbated a problem that was already there.

 

 

For people like me, Zolpidem is useless.

 

In fact, since it increases REM more, it might actually, in some ways, make things WORSE!

 

If you are born with a neurologic disease causing sleep-structure abnormalities, then you NEED to mess with your sleep-structure. How else am I supposed to recover from BURNOUT?

 

It's impossible with such a fractured structure as mine.

 

 

Of course, for MOST others, your advice is actually sound.



#4726 Finn

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Posted 11 December 2016 - 07:46 PM

 

Be careful with etiazolam, it is just another benzodiazepine, Tolerance is an issue, also withdrawl, but paws (post-acute withdrawl-syndrome) are much worse. Not everyone develop paws, but thos who does regret using benzos.

 

I know that in US you can get prescription for ambien CR, zolpidem does not mess the sleep architecture but side effects are as above.

 

---

 

 

Of course, for MOST others, your advice is actually sound.

 

In Finland and Denmark etizolam has been added to narcotics lists, don't know of Sweden and Norway, if it isn't classified as a narcotic yet there, it will probably soon be, so if you are considering ordering it, that could be somewhat risky.


Edited by Finn, 11 December 2016 - 07:59 PM.

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#4727 paintballman

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Posted 11 December 2016 - 08:41 PM

I was thinking about going into a nsi 189 study, only problem is that I would have to stop taking my antidepressent.  I would have a 40% chance of getting the real deal, 60% of placebo.


I was thinking about going into a nsi 189 study, only problem is that I would have to stop taking my antidepressent.  I would have a 40% chance of getting the real deal, 60% of placebo.



#4728 Mind_Paralysis

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Posted 11 December 2016 - 09:36 PM

 

 

Be careful with etiazolam, it is just another benzodiazepine, Tolerance is an issue, also withdrawl, but paws (post-acute withdrawl-syndrome) are much worse. Not everyone develop paws, but thos who does regret using benzos.

 

I know that in US you can get prescription for ambien CR, zolpidem does not mess the sleep architecture but side effects are as above.

 

---

 

 

Of course, for MOST others, your advice is actually sound.

 

In Finland and Denmark etizolam has been added to narcotics lists, don't know of Sweden and Norway, if it isn't classified as a narcotic yet there, it will probably soon be, so if you are considering ordering it, that could be somewhat risky.

 

 

I am not considering ordering it - but I thank you for providing some info regarding the legalities. = )

 

Gabapentin is where it's frakkin' at! : D
 



#4729 jaybird10 2

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Posted 11 December 2016 - 09:40 PM

Be careful with etiazolam, it is just another benzodiazepine, Tolerance is an issue, also withdrawl, but paws (post-acute withdrawl-syndrome) are much worse. Not everyone develop paws, but thos who does regret using benzos.

I know that in US you can get prescription for ambien CR, zolpidem does not mess the sleep architecture but side effects are as above.


---


Of course, for MOST others, your advice is actually sound.
In Finland and Denmark etizolam has been added to narcotics lists, don't know of Sweden and Norway, if it isn't classified as a narcotic yet there, it will probably soon be, so if you are considering ordering it, that could be somewhat risky.

I am not considering ordering it - but I thank you for providing some info regarding the legalities. = )

Gabapentin is where it's frakkin' at! : D

Do you experience tolerance issues after longterm use?

#4730 Neuronaut91

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Posted 12 December 2016 - 03:45 AM

I used NSI189 for my OCD in the past, I had previously used the free base version but the side effects were too much to bear. Ive been using NSI189 phosphate at 30mg twice a day for the past 60 days to learn my material for personal training and I must say it worked like an absolute miracle. Not only has it enhanced my memory but in a weird way it also seems to create an inability to feel gabaergic withdrawal. It has made me empathetic as well. I also stacked it with Dihexa and NA Semax Amidate at one point but found the combination a bit overwhelming.
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#4731 Twindaddy37

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Posted 12 December 2016 - 04:30 PM

For all those of you struggling with sleep issues, racing thoughts, etc, i will share my own experience of what works for the best night sleep. I've tried it ALL. The following is my sleep stack, which works like a charm every time. 

 

Lithium orotate 5-10mg (depending on how stressful the day was, if stressful 10mg, if not 5mg)- completely shuts down racing thoughts (this is probably my top supplement of all time). 

Lions mane- 1500mg from powdercity (for me this supplement 100% puts me in a deep REM sleep)

magnesium citrate- 1/2 tsp from bulkpowders.

Glycine 3grams nightly

Uridine 450mg 2x daily.

1 gram of high quality high DHA fish oil 

Phenibut (only on weekends 500mg on sat and sun am, both those two days i get amazing restorative sleep, and it doesn't effect my sleep going into the week).

 

hope this helps. 


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#4732 Strangelove

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Posted 12 December 2016 - 05:56 PM

 

 

If you're having trouble sleeping, have you tried Etizolam? 2mg of that helps me sleep very easily and I don't feel groggy the next day. I think sleep is the most important thing we need in our lives, after air and water. And I would much rather risk tolerance to medications that help me sleep soundly than miss it altogether and turn into a grumpy, non functional mess the next day!

 

Etizolam is probably the best sleep aid on the planet. Two milligrams will knock you out cold and give you eight to ten hours of deep, restorative sleep. Try it with some glycine, prazosin, and melatonin and you likely enjoy the best sleep you’ve ever had. Great thing about eti is that it takes at least several weeks to build up a tolerance to it, and when you do finally reach that point, all you have to do is lay off for a week or two and all the receptors reset themselves back to normal. It’s cheap, legal, and easily obtainable (although not nearly as easily as it was a couple of years ago). It is very hard to get addicted to, unlike the benzos. I took two milligrams almost every day for almost a year, quit cold turkey, and just shrugged off the worst of the withdrawal in about five or six days. In two weeks it was gone completely. And it’s nowhere near as miserable as benzo withdrawal. Right now I’d say it’s as close to the perfect sleep solution as currently exists. The half-life of the stuff is almost perfect, too—no walking around like a zombie the next day or falling asleep at work.

 

 

The research has shown that etizolam reduces REM sleep. I can't be bothered to pull up the papers right now but REM sleep reduction has been noted, and I remember an author saying that it may actually increase slow wave/deep sleep which is cool.

 

Anyway, my understanding is Strangelove is no longer offering NSI-189? So there's no way to get it?

 

 

No, I still ship to other members both freebase and phosphate at the usual $24-$16/gram, free airmail or $5 for registered mail.

 

PRL-8-53 at $15/gram.


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#4733 Strangelove

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Posted 12 December 2016 - 06:14 PM

I used NSI189 for my OCD in the past, I had previously used the free base version but the side effects were too much to bear. Ive been using NSI189 phosphate at 30mg twice a day for the past 60 days to learn my material for personal training and I must say it worked like an absolute miracle.

 

Me and a few others have similar results. I can use freebase with no much side effects but I started using phosphate now orally and its smoother.

 

Sublingual freebase has better bioavailability, 20mg can be enough and oral phosphate can be smoother to some that get anxiety. Maybe the slower come up reduces anxiety cannot really explain it.

 

Speaking of anxiety... I got a few PMs other members worried that would have an increase in anxiety trying NSI-189. NSI-189 is not anxiogenic per se, the majority using it get mood boost and more positive thinking patterns. Its one of the drugs that somehow is similar to psychedelics only in the set and settings sense...

 

At least for me, NSI-189 makes me optimistic and can greatly increase confidence, but few times that I tried it, that I had a real word pressing  issue to resolve, health or financial, I started overthinking and stuck even more, if I would not have taken NSI-189. I am getting a kind of seriousness from NSI-189 that most of the time is positive, but if I have a real problem, the seriousness and confidence bring me in mindset to find a solution, if I do not have a solution soon, I am getting anxiety. Its the opposite with subjective negative ideas, they just do not appear...


Edited by Strangelove, 12 December 2016 - 06:17 PM.

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#4734 Mind_Paralysis

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Posted 12 December 2016 - 08:02 PM

 

I used NSI189 for my OCD in the past, I had previously used the free base version but the side effects were too much to bear. Ive been using NSI189 phosphate at 30mg twice a day for the past 60 days to learn my material for personal training and I must say it worked like an absolute miracle.

 

Me and a few others have similar results. I can use freebase with no much side effects but I started using phosphate now orally and its smoother.

 

Sublingual freebase has better bioavailability, 20mg can be enough and oral phosphate can be smoother to some that get anxiety. Maybe the slower come up reduces anxiety cannot really explain it.

 

Speaking of anxiety... I got a few PMs other members worried that would have an increase in anxiety trying NSI-189. NSI-189 is not anxiogenic per se, the majority using it get mood boost and more positive thinking patterns. Its one of the drugs that somehow is similar to psychedelics only in the set and settings sense...

 

At least for me, NSI-189 makes me optimistic and can greatly increase confidence, but few times that I tried it, that I had a real word pressing  issue to resolve, health or financial, I started overthinking and stuck even more, if I would not have taken NSI-189. I am getting a kind of seriousness from NSI-189 that most of the time is positive, but if I have a real problem, the seriousness and confidence bring me in mindset to find a solution, if I do not have a solution soon, I am getting anxiety. Its the opposite with subjective negative ideas, they just do not appear...

 

 

Interesting!

 

Maybe this is why I actually found it to be anxioLYTic when stacked with Modafinil - moda' treats my SCT and extreme fatigue from burnout - without it, I CAN'T actually solve many issues which crop up - hence, I get a negative experience while on NSI.

 

I'm currently off NSI-189 AGAIN (after about 1,5 weeks on it, at 20 mg / day) - only doing Tianeptine during the day now, and it's MARKEDLY less sedating - it seems like most of the sedation was from NSI-189.

 

Soon... SOON!

 

I will have:

 

Atomoxetine

Modafinil

Gabapentin

 

Soon... my stack shall be complete! And I shall finally be free from my problems...

 

...Well, for a while! Until I run out of one of the above!
 

I think I'll try 40 mg daily (20 x 2 mg) once more when I have the needed supplies. Oh! Gotta' get me some Magnesium and Omega-3 again too.


Edited by Stinkorninjor, 12 December 2016 - 08:24 PM.


#4735 Twindaddy37

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Posted 12 December 2016 - 08:53 PM

Has anyone stacked curcumin with the NSI-189, for increased Hippocampus neurogenesis? 

According to pub med- 

 

"The low molecular weight and polar structure of curcumin allows it to penetrate the blood-brain barrier effectively. Animal studies have indicated that curcumin can enhance the adult hippocampus neurogenesis process by increasing the number of newly generated cells in the dentate gyrus region of hippocampus[2]"


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#4736 Mind_Paralysis

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Posted 12 December 2016 - 09:04 PM

 

Hmm yes as you've said we seem to really have many similar issues. I also don't seem to ever get proper sleep, going by the fact that i wake up tired nearly daily.

 

How is you're Atomoxetine trial going? I'm taking my last pill tomorrow, which will means i've been on it for 6 weeks at 80mg/day. Another disappointment!
 

 

 

I'm sad to hear it didn't work for you. : (

I think it worked a bit for me though! At 40 mg per day, I was starting to make some gains! = ) I had a slight increase in reaction-time (did some testing - about 15% faster than normal) and I was starting to notice effects on anxiety, OCD and most importantly... endurance, wakeness, and MOTIVATION!

 

When I have it available again, I will start up at 40 mg again, and then possibly move up to 60 mg eventually. (SHOULD be my target-dose - I weigh about 63 kilos and I have CYP2D6-mutations, which means I should use about 25-33% less of a dose than most peeps, so 60 mg should be pretty DAMN good.)

 

I might need to stack it with low-dose Modafinil though, because it WAS making me terribly tired at 40 mg... Should be an incredibly synergistic combo.

 

Have you considered stacking ATX with 100 mg Modafinil? Some swear by this combo, you know.

 

 

 

 

 

 

 

I am not considering ordering it - but I thank you for providing some info regarding the legalities. = )

Gabapentin is where it's frakkin' at! : D

Do you experience tolerance issues after longterm use?

 

 

Unknown - it's all theoretical at this point - I haven't actually tried it.

 

I have high hopes though!

 



#4737 Valijon

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Posted 13 December 2016 - 03:35 PM

For all those of you struggling with sleep issues, racing thoughts, etc, i will share my own experience of what works for the best night sleep. I've tried it ALL. The following is my sleep stack, which works like a charm every time.

Lithium orotate 5-10mg (depending on how stressful the day was, if stressful 10mg, if not 5mg)- completely shuts down racing thoughts (this is probably my top supplement of all time).
Lions mane- 1500mg from powdercity (for me this supplement 100% puts me in a deep REM sleep)
magnesium citrate- 1/2 tsp from bulkpowders.
Glycine 3grams nightly
Uridine 450mg 2x daily.
1 gram of high quality high DHA fish oil
Phenibut (only on weekends 500mg on sat and sun am, both those two days i get amazing restorative sleep, and it doesn't effect my sleep going into the week).

hope this helps.


Any issues with daytime drowsiness?

#4738 Twindaddy37

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Posted 13 December 2016 - 06:19 PM

No issues with daytime drowziness. If your really having sleep issues there are many things you can do. As a standard every night after the sun goes down i wear blue light blocker glasses. Can find on amazon. Always go to bed before 11pm. Cold showers before bed. Look into grounding if you spend alot of time around electronics. Occasionally i shine an infrared light bulb i have in ceramic casing on my face for 15 mins, while wearing tanning goggles (this always seems to put me in a sleep trance, i dont know the science behind it and the warming of the head could be inducing a tranquil state that allows mind to slow down. Also i always meditate at approx 8pm for 15 minutes. This clears the mind from the day. Hope this helps.

Edited by Twindaddy37, 13 December 2016 - 06:21 PM.


#4739 Mind_Paralysis

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Posted 13 December 2016 - 10:56 PM

No issues with daytime drowziness. If your really having sleep issues there are many things you can do. As a standard every night after the sun goes down i wear blue light blocker glasses. Can find on amazon. Always go to bed before 11pm. Cold showers before bed. Look into grounding if you spend alot of time around electronics. Occasionally i shine an infrared light bulb i have in ceramic casing on my face for 15 mins, while wearing tanning goggles (this always seems to put me in a sleep trance, i dont know the science behind it and the warming of the head could be inducing a tranquil state that allows mind to slow down. Also i always meditate at approx 8pm for 15 minutes. This clears the mind from the day. Hope this helps.

 

Sounds like you have a pretty good sleep schedule and sleep-method down there - I've tried implementing similar things myself, but my combo of both ADHD and SCT makes it super-hard to implement these kind of changes.

I've installed F.lux on both my computer and my phone, I've installed a service which shuts down my computer at 22.30,  I take melatonin at 21.00 hours, along with Mirtazapine, but it doesn't seem to be enough...

 

I'm thinking I need to start taking melatonin EVEN earlier...! Perhaps take blue-light filtering to the next level, and get some glasses. Some SCT-ers on ADDforums have reported relief from sleep-issues if, and ONLY, if, they go to sleep BEFORE 21.00 hours! Apparently there's something wrong with our circadian rhytms, on a fundamental level - if we don't sleep before these hours, then it doesn't matter if we sleep 10-11 hours - we STILL won't enter deep-sleep...!

 

It's truly aggravating this... Hopefully my Gabapentin shows up soon, because I'm at my wits end with this. In theory, it should do the trick... but in theory, so should Clonidine have, and it wasn't enough! I actually woke up a LOT on that one...! In theory, Alpha-2-agonists are SWS-enhancing, but apparently not enough. (in theory, so is Mirtazapine, but it's not enough for me - higher dosages actually seem to wake me up MORE, from Alpha-2-ANTagonism, d'oh!)
 



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#4740 Twindaddy37

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Posted 14 December 2016 - 02:42 AM

Trust me when i tell you i had the most destroyed sleep achitecture on the planet, from about 15 yrs of hammering it with sleep meds and other things. It can be fixed. It took about a year to correct it, if not more. The key was not taking anything in that time to mess with it, includig melatonin. If you do take it i think its best to take 6 hours or so before sleep, not 30 minutes. Melatonin did more harm than good for me. I would absolutely get the blue light blockers. Especially if your exposed to alot of artificial light after the sun goes down. I generally rely on mostly candle light after 8pm. Hardcore i know, but it works.





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