6219 replies to this topic

[bruffellz]

FTIR and melting point testing indicates that VLK's is identical to Nyles7's product. 

 

Both have a melting point of about 175 degrees C.

 

The attached FTIR spectra are a near perfect match, too:

 

I attached some references for the bonds that may be present if someone wants to compare to the molecular structure: 

 

If someone wants to send a sample from another batch, I can test that, too. PM me if you want the address.

 

Can anyone confirm these results as legitimate?

[tdmonster99]

Just noticed NutrAction has a limited stock of NSI-189 now if anyone is interested

http://nutraction.com/shop/nsi-189/

[swolo]

 

FTIR and melting point testing indicates that VLK's is identical to Nyles7's product. 

 

Both have a melting point of about 175 degrees C.

 

The attached FTIR spectra are a near perfect match, too:

 

I attached some references for the bonds that may be present if someone wants to compare to the molecular structure: 

 

If someone wants to send a sample from another batch, I can test that, too. PM me if you want the address.

 

Can anyone confirm these results as legitimate?

 

I messaged user joeyo about his testing. He corroborated with what Flex posted, that his limited testing was showing that the substance was not NSI-189. He said he'll be doing a different kind of test this week to confirm; the test he did was hampered by the sample's low solubility. I asked joeyo to post what he said to me in this thread but for some reason he hasn't. He's just incredibly busy and not very responsive.

 

Just noticed NutrAction has a limited stock of NSI-189 now if anyone is interested

http://nutraction.com/shop/nsi-189/

Thanks, pre-ordered.

 

Ceretropic said their NSI-189 derivative passed customs a few days ago. Crossing my fingers that there are no more delays.

Edited by swolo, 05 June 2014 - 05:07 AM.

[world33]

Second day on NSI-189 (2 daily doses of 20mg). Increased vision acuity, concentration, slight better stamina and an overall better state of mind. I also managed to half my 20mg escitalopram daily dose to 10mg without feeling any withdrawal effect! I hope this is gonna last. I am surprised to feel these effects so soon. I thought adult neurogenesis would take weeks to take effect. There must be another fast acting mechanism of action. If this is going to last I can hopefully throw away my SSRI for good and invest some money on Neuralstem Inc shares hehehe. I hope it is not too good to be true.

[verticalVagabond]

 

FTIR and melting point testing indicates that VLK's is identical to Nyles7's product. 
 
Both have a melting point of about 175 degrees C.
 
The attached FTIR spectra are a near perfect match, too:
 
I attached some references for the bonds that may be present if someone wants to compare to the molecular structure: 
 
If someone wants to send a sample from another batch, I can test that, too. PM me if you want the address.

 
Can anyone confirm these results as legitimate?
 

I messaged user joeyo about his testing. He corroborated with what Flex posted, that his limited testing was showing that the substance was not NSI-189. He said he'll be doing a different kind of test this week to confirm; the test he did was hampered by the sample's low solubility. I asked joeyo to post what he said to me in this thread but for some reason he hasn't. He's just incredibly busy and not very responsive.
 

Just noticed NutrAction has a limited stock of NSI-189 now if anyone is interested
http://nutraction.com/shop/nsi-189/

Thanks, pre-ordered.
 
Ceretropic said their NSI-189 derivative passed customs a few days ago. Crossing my fingers that there are no more delays.

Do we have confirmation on whether Nyles7's product is legitimate? If I recall there was some difference between Nyles7's product and Science guy's, attributed to Nyles7's being the freebase form?

[medievil]

Second day on NSI-189 (2 daily doses of 20mg). Increased vision acuity, concentration, slight better stamina and an overall better state of mind. I also managed to half my 20mg escitalopram daily dose to 10mg without feeling any withdrawal effect! I hope this is gonna last. I am surprised to feel these effects so soon. I thought adult neurogenesis would take weeks to take effect. There must be another fast acting mechanism of action. If this is going to last I can hopefully throw away my SSRI for good and invest some money on Neuralstem Inc shares hehehe. I hope it is not too good to be true.

Escitalopram never caused any withdrawal symtions for me.

[swolo]

joeyo, via messaging on this forum, wanted me to post that thus far he has no certain conclusions regarding the composition of VLK's NSI-189, but that he should have more results tomorrow. Not sure why he doesn't just post in this thread...

[world33]

[/quote]
Escitalopram never caused any withdrawal symtions for me.
[/quote]

I did experience extreme tiredness and lack of concentration/brain fog the couple of times I tried to stop just after 2 days.
By the way the NSI-189 I tried is the one form Nyles7 so it must be legit considering the positive effects I am feeling. I am just surprised on the quick response. If someone does not experience much it may be possible that he does not need it in the first place and there is no underlying issue or it is not the proper compound.
I just ordered 50 grams from the Alibaba supplier to compare the difference with the one from Nyles7. If it is as effective as Nyles7's one I plan to keep 40 grams and give 5 grams to a couple of people who have already asked for in this forum. Send me a private message if you want to know the Alibaba supplier. I am not here to advertise or endorse companies especially considering I have not tried their stuff first and they are based in China. Alternatively you can use the Alibaba search field and look for NSI-189; the same company appears many times in different listed items with different titles and keywords (I guess for search engine optimization purposes).
The verified/gold Alibaba supplier sells at the following prices after negotiation:
10 grams 200 dollars (20$ per gram)
50 grams 500 dollars (10$ per gram)
100 grams 1000 dollars (10$ per gram)

The minimum order is 100 grams but if you negotiate you can go down to 50 grams and 10 grams for a sample to test (that is the trick to ask much smaller quantities at first).
Escrow payment commission is 5% on total amount but other payment options are available. No Paypal I think.

Edited by world33, 05 June 2014 - 10:45 PM.

[foreseason]

For anyone considering purchasing NSI-189 from Transhuman Technologies, this has been my experience with them so far. 

 

Almost 4 weeks ago (May 15) I contacted them after hearing they would soon be stocking NSI-189.  At the time I had found another trusted source of NSI-189 and was trying to decide where to purchase it from.   I emailed THT and asked about their company/products, when NSI-189 would be available, and why I should buy from them.

 

On the 19th I received an email from them which said:

NSI-189 should be available within the next few days.

In addition, they offered to give me a free sample to test.  I was excited about this because it seemed I would be getting free NSI-189 very shortly. 

 

After not hearing back for a few days I emailed again to check the status.

 

Curious when I should expect this sample to be sent. I only ask because I am very eager to get some NSI-189 and if it's a little ways off still I will probably purchase some elsewhere to hold me over.
Thanks.

 

They replied:

Testing results just came back. We'll probably ship the sample on Mon or Tues. Definitely within the week, that's for sure.

 

Monday or Tuesday would have been May 23rd/24th.  Within the week would have been by May 27. 

 

On May 27, after still not hearing anything or receiving any product, I emailed again. 

 

Will there be tracking or shipment notification or should I just expect to see it pop up in my mailbox?  USPS?

 

No reply to this email. 

 

On May 31, after noticing their web site was down, I tried contacting them again. 

 

With the site being down for a month I assume the NSI-189 is delayed? Are you still sending out samples? Did they go out last week like you were planning?

I hate to push the issue but I am able to get some elsewhere if it is in fact delayed

 

Later that day I received a reply:

 

Your NSI-189 should have already shipped. If for some reason it hasn't, we'll be sure to get it out immediately.

 

Should have been shipped?  I'm assuming this is a pretty small operation and whether or not something was shipped should be obvious. 

 

On June 4th I replied:

 

Haven't received it yet but I'm keeping my eye out.  You guys are based in the US correct?  Was it shipped USPS?

 

No reply to this email. 

 

Basically, they have been very vague with me and the two times I asked for specific shipment information, I received no replies.  My frustration lies in the fact that I was very clear about wanting NSI-189 quickly and, if that wasn't possible, I could purchase it elsewhere.  If they would have told me it would be at least a month until I received it, I would have gone elsewhere.  But, from the start, I've been hearing "a few days."  For all I know, their products may be great.  Their customer service, however, seems to be lacking. 

 

A couple days ago I bit the bullet and purchased some NSI-189 from NutrAction.  after watching their inventory quickly disappearing, and not knowing if, or when, I would receive my product from THT, I had to pull the trigger. 

 

I will continue to update on the THT situation.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

[p3x888]

 

 

 

FTIR and melting point testing indicates that VLK's is identical to Nyles7's product. 
 
Both have a melting point of about 175 degrees C.
 
The attached FTIR spectra are a near perfect match, too:
 
I attached some references for the bonds that may be present if someone wants to compare to the molecular structure: 
 
If someone wants to send a sample from another batch, I can test that, too. PM me if you want the address.

 
Can anyone confirm these results as legitimate?
 

I messaged user joeyo about his testing. He corroborated with what Flex posted, that his limited testing was showing that the substance was not NSI-189. He said he'll be doing a different kind of test this week to confirm; the test he did was hampered by the sample's low solubility. I asked joeyo to post what he said to me in this thread but for some reason he hasn't. He's just incredibly busy and not very responsive.
 

Just noticed NutrAction has a limited stock of NSI-189 now if anyone is interested
http://nutraction.com/shop/nsi-189/

Thanks, pre-ordered.
 
Ceretropic said their NSI-189 derivative passed customs a few days ago. Crossing my fingers that there are no more delays.

Do we have confirmation on whether Nyles7's product is legitimate? If I recall there was some difference between Nyles7's product and Science guy's, attributed to Nyles7's being the freebase form?

 

 

I can say this, so take it for what's worth. I have ordered twice from him. Both batches, "tasted" and looked the same. Both had the same effect on me. My mood improved, I was very talkative, and basically enjoyed the day more.

 

So, to me, it seems that his stuff is legitimate and it was both times I ordered it was.

 

I also have VLK's. Its much fluffier and takes up 5x the space for the same 5 grams. I haven't tested it yet.

 

Hope this helps in some way.

 

[spookytooth]

I have been using VLK's NSI for a little while now and the taste and effects seem to be very similar to ScienceGuy's NSI. I am not 100% sure about this though as I didn't keep any of ScienceGuy's NSI for a direct comparison.

The fluffiness was very distinct to ScienceGuy's NSI too. It seemed a little fluffier even than VLK's. This might be due to different ways of storing them I guess?

 

 

 

 

FTIR and melting point testing indicates that VLK's is identical to Nyles7's product. 
 
Both have a melting point of about 175 degrees C.
 
The attached FTIR spectra are a near perfect match, too:
 
I attached some references for the bonds that may be present if someone wants to compare to the molecular structure: 
 
If someone wants to send a sample from another batch, I can test that, too. PM me if you want the address.

 
Can anyone confirm these results as legitimate?
 

I messaged user joeyo about his testing. He corroborated with what Flex posted, that his limited testing was showing that the substance was not NSI-189. He said he'll be doing a different kind of test this week to confirm; the test he did was hampered by the sample's low solubility. I asked joeyo to post what he said to me in this thread but for some reason he hasn't. He's just incredibly busy and not very responsive.
 

Just noticed NutrAction has a limited stock of NSI-189 now if anyone is interested
http://nutraction.com/shop/nsi-189/

Thanks, pre-ordered.
 
Ceretropic said their NSI-189 derivative passed customs a few days ago. Crossing my fingers that there are no more delays.

Do we have confirmation on whether Nyles7's product is legitimate? If I recall there was some difference between Nyles7's product and Science guy's, attributed to Nyles7's being the freebase form?

 

 

I can say this, so take it for what's worth. I have ordered twice from him. Both batches, "tasted" and looked the same. Both had the same effect on me. My mood improved, I was very talkative, and basically enjoyed the day more.

 

So, to me, it seems that his stuff is legitimate and it was both times I ordered it was.

 

I also have VLK's. Its much fluffier and takes up 5x the space for the same 5 grams. I haven't tested it yet.

 

Hope this helps in some way.

 

 

 

[p3x888]

I don't know. Nyles7's is very grainy. I usually mash it to break up the pieces so it will dissolve under my tongue easier. It is VERY different from the VLK batch. Like i mentioned, it takes up something like 5x the space as Nyle's version.

 

I guess the best test is for me to just try VLK's and see if it has the same effects.

[typ3z3r0]

Perhaps it is because nyles7's first batch may have been NSI-189 base, not phosphate? 

[p3x888]

Yes, I think is likely. But i am not sure this was his first batch or not. I have bought it twice.

[neuralis]

hmm.. this deal with tht seems kinda shady, which is a bummer.. I was hoping to get my hands on some nsi soon

keep us updated how it all plays out

[foreseason]

Still no reply or product from tht. Just checked my mailbox.

Edited by foreseason, 10 June 2014 - 09:53 PM.

[Flex]

So, here is the Second testing of NSI-189 from Joeyo but this time with DMSO as solvent.

Regarding to him, it looks good.

 

 

Edit:

Forgot to mention that I´ve recieved it as a PDF and had to convert it in JPG,

because I wasnt allowed to upload a PDF.

I checked the Image and its the same.

Nothing is missing.

Edited by Flex, 11 June 2014 - 09:25 PM.

[Adaptogen]

terrific, it's a relief to hear that the analysis correlates. can anyone verify that this data matches that of nsi-189?

[themadscientist]

Hey whats up everyone? 

 

I have been a long-time reader of this forum but just decided to make an account today. I have something interesting to share with everyone. So ever since I heard about NSI-189 i have been dying to get my hands on it. So i checked here actively almost everyday, and the two sources i noticed people discussing were tht.co and Alibaba. I emailed tht.co about NSI in late May and they offered to send me a sample. I emailed them twice after that but i did not get a response back. So I then decided to hit Alibaba and ordered a 1 gram sample for $70 with shipping. I received it 2 days ago but have yet to try it. But today to my surprise i received a package from that.co, and it was indeed NSI-189. The packaging was really awesome and high quality. The NSI-189 it self had a strong chemical smell when compared to the version i received from Alibaba, which had no smell at all. I will post some pictures once i host  them somewhere because i can't find an upload option on here.

[Flex]

I really dont want to be a scaremonger

But I just wanted to tell You to be careful with this Chinastuff.

The Chinese people could be sometimes fraudster and sell You something dangerous or polluted instead of the desired one.

 

Major Legend has answered some questions why this happens.

http://www.longecity...ys/#entry665146

 

Btw: apologizes for my bad english on post #2033..

[DaneV]

Be careful with suppliers from Alibaba. I would not ingest anything that came from a random source on alibaba since quality, safety and even morality in general is increadibly low China compared to us westerners. So god knows what they are sending you. I have no experience in importing chemicals but my repeated experience with various companies in china (very good, very bad and some in between) causes me to be careful with them.

 

Either put your trust in a reputable middleman who knows what`s he is doing or get the product tested by A third party. But that`s just my $ 0.02.

 

[foreseason]

From the other NSI-189 Thread.  Unfortunate news, but can't say I'm surprised

Hey Guys, I figured I would comment here so that people who do not frequent Reddit can be up to speed with what is going on as well. Last week we were sent a cease and desist letter from Neuralstem's lawyers. While we feel that their use patent does not cover the sale of a research chemical, and certainly does not cover our analog, they made it clear that if we were to go forward, they would make our lives hell. So while we feel that legally our analog would be perfectly fine, we do not want to get into a fight with a billion dollar company. They made it clear that they would alert various government agencies to our operation, and generally make things harder for us to do business. So it is in our best interest to back down from the sale of NSI-189, or any direct structurally related analogs.

 

Sorry to get people's hopes up. We respect that Neuralstem spent a lot of money to get this compound through trials, and need to assert their legal control of their patents. We just didn't think they would come after us before we even put it up on the site. Obviously they have people reading these forums, and knew about things ahead of time. It's unfortunate that this will make it harder for people to get this great compound, but we understand why they did what they did. We are going to move on and focus on our other new compounds.

 

[foreseason]

Update:

 

Today I received my NSI-189 sample from Transhuman Technologies.  It came very professionally packaged and safety sealed.  No certificate of authenticity/test results but appears to be legit.  Have not tried it yet.

 

As i said above, I would have liked better communication and a more accurate portrayal of when the product would be available. But they did deliver a free sample as promised. 

 

However, after reading Ceretropic's post about the cease and desist letter from nueralstem, I wouldn't be surprised if other companies, such as THT, run into the same problems. 

[themadscientist]

Here is the nmr from the alibaba source which is Wuhan HengHeDa Pharm Co



Here is the packaging from tht.co

 

Attached Files

•  nmr of nsi.png   163.44KB   2 downloads
•  Optimized-IMG_9079.jpeg   788.13KB   3 downloads

[world33]

Thanks themadscientist,
Can you explain whether the NSI-189 from Wuhan HengHeDa Pharm Co is good or not? I do not really understand that nmr graph you posted.
cheers

Edited by world33, 12 June 2014 - 12:48 AM.

[themadscientist]

I'm not really knowledgeable with this type of stuff, but based on quick comparison with the other NMRs of NSI-189  i have  seen it doesn't seen to match with the rest.

[world33]

Did you get it tested yourself or did you receive the nmr graph from the company? Did you buy both from Wuhan HengHeDa Pharm Co and tht.co ?

[themadscientist]

The graph came from hengheda pharm. I did not get it tested.

The packaged version came from tht.co and it was a free sample.

[world33]

Can anyone with chemistry background have a look at the nmr graph and tell whether the Wuhan HengHeDa Pharm Co NSI-189 could be legit?

Edited by world33, 12 June 2014 - 01:08 AM.

[themadscientist]

but to be honest now that i received the version from THT.co, I really think the stuff I received from china is not NSI-189 it has no smell, no taste, and its extremely light. It might be fake, but who knows.