30 replies to this topic

[victortsoi]

So I bought the uridine from amazon (there is only one brand right now) that comes in 25mg pills.
The form is triacetyluridine. I am taking them twice a day with my fish oil for a total of 50mg uridine a day. I have never seen any dosing information anywhere, so please help me out guys. Thanks.

[Hebbeh]

So I bought the uridine from amazon (there is only one brand right now) that comes in 25mg pills.
The form is triacetyluridine. I am taking them twice a day with my fish oil for a total of 50mg uridine a day. I have never seen any dosing information anywhere, so please help me out guys. Thanks.

http://www.longecity...ne-uridine-dha/

[victortsoi]

The dosages are all over the place there.

[Hebbeh]

The dosages are all over the place there.

Apparently everybody reacts a little differently. I've been taking it for almost a year. I never noticed much effect from the TAU form that you're using even up to 150mg...but some claim they can't tolerate more than 50mg of TAU without brain fog. I permanently cured my brain fog issues with 250-300 mg of UMP sublingually first thing every morning. I wake clear minded first thing in the morning and get by on less sleep and less caffeine.

[victortsoi]

I mean, this guy says

:Bipolar may have roots in certain lipid envelope virii - HSV-1 seems to be the most common. I'd look at daily valacyclovir, tromantadine if you test positive for HSV-1 antibodies.


You may have more success with uridine if you take between .5g to 5g daily and sufficient DHA.

i take 50 MG per day, and he is advocating 500?! This is why I am so confused.

http://www.ncbi.nlm....ubmed/21945379/
Edited by MrHappy, 19 October 2011 - 04:23 PM.

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[Hebbeh]

I prefer the UMP powder sublingually first thing in the morning. Start with 100 mg of UMP (half a scoop) sublingually and titrate up if need to a full scoop (250 mg). That is what works for me and makes me feel mentally at my best.

edit: and with 250mg sublingually first thing in the morning, I no longer need to start my day with caffeine...in fact I feel better without caffeine until later in the day and that never used to be the case.

Edited by Hebbeh, 14 October 2012 - 02:31 AM.

[victortsoi]

OMG, so is the 50mg a day im taking doing anything?

[victortsoi]

There was a post in the big uridine thread that warned that over 100mg a day is harmful. (to DNA). ????

[Hebbeh]

There was a post in the big uridine thread that warned that over 100mg a day is harmful. (to DNA). ????

That was speculation based on a study performed in a vitamin B (folic acid) deficient state. It was discussed in detail and the consensus was that it wouldn’t occur with adequate nutrition and B vitamin intake. I'm sure everybody here meets the RDA and it won't be a problem. You can pose the question to MrHappy in the big thread and I'm sure he will go into detail as he is the resident expert about uridine and has researched it extensively. I'm comfortable that it's not an issue.

[Renegade]

75mg TAU got me SO fogged and anxious yesterday. Think I will give things a rest for a few days as I've been experimenting with lots of noots and start on 25 mg & work up from there.

[victortsoi]

I posted this in the mega thread, but what is the conversion between uridine and TAU?

[Renegade]

Im about 40 pages into the mega thread. I remember reading it's 4x in humans.

[Hebbeh]

I posted this in the mega thread, but what is the conversion between uridine and TAU?

It's speculative at best...nobody knows. I've seen some people attempt to make comparisons but it is simply off the cuff guesses at best that have no basis. Some seem to have positive experiences with TAU but from what I've read, most react more positively to UMP....especially sublingual UMP. Personally, I never experienced much with up to 150mg of TAU but have excellent results with 200-300mg sublingual UMP. I, along with others, have tried TAU sublingual but it doesn't dissolve and absorb through the mucosa very well. This is explained by TAU being fat soluble and UMP being water soluble. If you are going to use TAU, it would be advised to take it with a source of fat so that it can be absorbed.

[victortsoi]

Im about 40 pages into the mega thread. I remember reading it's 4x in humans.

you mean 25mg TAU=100mg uridine? Thanks.

[Renegade]

Im about 40 pages into the mega thread. I remember reading it's 4x in humans.

you mean 25mg TAU=100mg uridine? Thanks.

Yes seemed to be the conclusive consensious in the 'mega thread.'

[Hebbeh]

Im about 40 pages into the mega thread. I remember reading it's 4x in humans.

you mean 25mg TAU=100mg uridine? Thanks.

Yes seemed to be the conclusive consensious in the 'mega thread.'

This isn't correct. There is no way to compare dosages of TAU and UMP. Anybody that claimed otherwise is pulling it out of thin air. Somebody please show me references to the contrary. Personally, TAU never did much for me at any dose and the difference between TAU and UMP is very individualistic. Anecdotal reports are all over the board but most seem to have better results with sublingual UMP.

[victortsoi]

Im about 40 pages into the mega thread. I remember reading it's 4x in humans.

you mean 25mg TAU=100mg uridine? Thanks.

Yes seemed to be the conclusive consensious in the 'mega thread.'

This isn't correct. There is no way to compare dosages of TAU and UMP. Anybody that claimed otherwise is pulling it out of thin air. Somebody please show me references to the contrary. Personally, TAU never did much for me at any dose and the difference between TAU and UMP is very individualistic. Anecdotal reports are all over the board but most seem to have better results with sublingual UMP.

what did it "do" for you, out of curiosity? Perhaps it is the noopept, but I have gotten to work on some long term goals and ditched some very bad habits that I had struggled with for years-in effect, I have taken "control" of my life and myself whereas before I felt as if I was a slave to my unsavory habits. I don't want to go into too much detail, but I guess the concise description of my "changes" would be increased motivation, focus, and mood.

[Hebbeh]

what did it "do" for you, out of curiosity? Perhaps it is the noopept, but I have gotten to work on some long term goals and ditched some very bad habits that I had struggled with for years-in effect, I have taken "control" of my life and myself whereas before I felt as if I was a slave to my unsavory habits. I don't want to go into too much detail, but I guess the concise description of my "changes" would be increased motivation, focus, and mood.

Here is a post I made in the big thread last year after being on 250mg sublingual UMP for about a month...

Effects are very clean, clear headed, lucid mental energy which I haven't felt for a long time....I'm 54 and suddenly I feel mentally 10+ years younger....just like I should...and want to feel. Also, I can't sleep for much more than 5-6 hours when I was just barely getting by on 7 before. Focus, productivity, and motivation are all much improved.

I've been using sublingual UMP for almost a year now and it has become one of my must have supplements. I used to suffer from chronic mental fatigue and relied on caffeine to get through the day. I often had trouble staying focused through the "brain fog" from the mental fatigue. Now I get by on less sleep and less caffeine with less mental fatigue and no longer suffer the fog and fatigue even though working 10+ hr days and still finding energy for fitness and a little social life. I especially notice clarity of thought as I previously mentioned. The results from a year ago are still as impressive today if not better. It seems I barely remember the fog of pre-UMP days. It has been a God send for me. But YMMV as anecdotal reports vary.

[victortsoi]

does taking uridine before bed get in the way of sleep?

[Hebbeh]

I prefer to use UMP sublingual first thing in the morning. I did also do a dose late afternoon for awhile but find it overkill now.

[Renegade]

I tried 25mg TAU this afternoon.

I have been feeling very clear headed the last few days so I had a good 'blank canvas' to try uridine again.

Within 30mins - I felt irritable and very foggy. I feel very stressed out and unresourceful when I take this supplement. I also had a mild headache, and headaches are rare for me.

I guess it's just not for me, unfortunately. On to the next wonder pill, I guess!

[victortsoi]

Uridine is awesome for me in the mornings. I do think that taking it too late at night with fish oil for a second dose (around 1-2 hours before I want to go to bed) interrupts my sleep schedule. I'll try not taking it a second time today.

[tintinet]

TAU also did nothing for me also. But I consider sublingual UMP the best supplement I've ever taken, in terms of apparent perceived positive effect.

[stablemind]

Make sure to ramp up the dosage slowly. Too much and you'll find yourself in a very flat, emotionless state. I find that at the right dose, it seems to have a very profound antidepressant effect. So much that it actually sends shivers down my spine. I believe I need a washout period every week because after taking it for a week straight I think it's effects start to go away (or maybe its dosage just becomes too concentrated due to a cumulative effect). Choline is not needed for its mood boosting effect, and I'm still testing to see if it does any good at all.

[Renegade]

I'm wondering whether it would be worth trying UMP after my very negative experiences with TAU. Any thoughts?

[stablemind]

I'm wondering whether it would be worth trying UMP after my very negative experiences with TAU. Any thoughts?

How much did you take? What kind of negative effects?

[Renegade]

Stablemind - see 3 posts up from my last post!

[tintinet]

I'm wondering whether it would be worth trying UMP after my very negative experiences with TAU. Any thoughts?

Many posters, myself included, have had very different responses (or lack thereof) to TAU and UMP. My response to UMP, along with CDP-choline and omega-3s, has been positive, so I advocate trying it.

[jolly]

LEF's Cognitex formula includes 50mg of Uridine.

[Climactic]

LEF's Cognitex formula includes 50mg of Uridine.

Could this be any more vague? LEF has more than one Cognitex product, not all of which have uridine. Moreover, I believe you were referring to UMP (uridine monophosphate) -- UMP is by no means the only uridine compound, with the other being TAU (triacetyluridine).