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Therapeutic use of psychedelics (mostly daily treshold doses)


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#61 leftside

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Posted 12 March 2013 - 05:01 PM

I'm certainly not recommending RC's as part of your regular vitamin supplements. 12mg of 2C-I nbome could kill you with a single dose - but hey - no need to worry about brain cancer in that case right?. The "recommended dose" is only 300-600 micrograms, with a "high" dose being 1mg. It's not so easy for the body to synthesise though. The best way I found was to disolve 10mg in 10mg of vodka and then add it to a nasal spray solution. Figure out how much of a "dose" you'll get from one spray and away you go... Hits you in about 5-10 mins and can last 8-12 hours. I liked doing it around 1pm so that I could still get a good nights sleep. Always felt great the next day.

I think I must have tried all the "trippy" RC's in the past year or two. Some were a lot of fun. Some were very insightful. Some were very challenging. For the benefits I received, I'm totally ok with losing a few brain cells. I'm also a firm believer that you are only on this planet once and that you should experience as many different wierd and wonderful experiences that you can. But also in moderation - i.e. dont' be messing with this stuff every day, or even every week. Once a month max.

That experimentation phase of my life is now over though, and I'm much more focussed on the positive effects of herbs/mushrooms/supplements/etc and nootropics.

#62 branks

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Posted 12 March 2013 - 09:57 PM

Nasal administration has been the reason for the majority of deaths. I highly reccomend buccal if you are going to gamble with your mind, life and health.

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#63 vali

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Posted 16 March 2013 - 09:55 AM

I've decided to give this a try. I'll be using dried salvia leaves, due to the fact that they are legal to purchase and take where I am, unlike LSD, and have been rather well studied, unlike those research chemicals.

A group using threshold doses of Salvia to help meditate described the benefits as:

1) Thoughts become much more focused and clear.
2) Distracting thoughts and worries almost completely vanish.
3) The effects begin in about 15 minutes and last for slightly under one hour.
4) The herb has a calming effect.


http://www.maps.org/news-letters/v09n1/09136sou.html


This is from using roughly 250-500 mg of dried leaf. The leaf is placed under the tongue and kept there for about ten minutes, while occasionally taking it out to chew. They reported the overall effect to be equivalent to a cup of coffee. They mention that 1.5 grams seems to be the max, since over that amount people start giggling.

0.5 grams... half of the subjects noticed a slight effect... a clearer than normal mind that is free from distractions. The other half noticed nothing at all.
1.0 grams...everyone noticed it when they were in a quiet room with no distractions. Mind is clear and meditation is unusually easy with few distracting thoughts. This dose was only detected by anyone when they were trying to meditate. The effect made it easier to concentrate without thoughts... a definite plus for meditation. If they, however, listened to music or did some activity they could not notice any effect at all.
1.5 grams... half of subjects notice a trance like state beginning to happen. Effect is slight but it inhibits meditation for some.
2.0 grams produced a slightly trance like effect for some people with time distortion. Generally people found that level too strong for meditation. The effect was enjoyable however... a bit dream like and time seemed to slow down.

http://www.maps.org/...meditation.html

I am a cautious person, and this is my first time, so I started with 50 mg of dried leaf ordered from a reputable company. I feel calmer, but this might be a side effect of doing something mildly risky and then having nothing bad happen. I also feel interested in engaging with the world around me, but then I always feel that way after taking a new drug. This was mostly likely nothing but placebo.

My goal is to find a dosage that improves my life and mindset without impairing my thinking. I'll post back here in a couple days or so and let you know how that search is going.
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#64 branks

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Posted 16 March 2013 - 06:36 PM

Salvia works on completely different mechanisms and receptors then traditional psychadelics. If anything it impairs short term memory. I would advise against using such a powerful plant, as it is also not nootropic.
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#65 vali

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Posted 16 March 2013 - 08:46 PM

The reason I got the idea of using it as a nootropic was because of the MAPS study I linked above. If you read it, you'll see that some people showed appreciable benefits. Improved concentration, a relaxed mood, and a general sense of well being are all emotions I strive for, and I think investigating Salvia is worth my time. That said, you're right about salvia working on different mechanisms, and I don't plan to use it daily. Like the group in the study, I'll be saving it for weekends and special events.

#66 branks

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Posted 16 March 2013 - 09:12 PM

Salvia is more akin to taking a delirient then a psychadelic. Its effects could hardly be called psychadelic, but they can be classified as hallucinogenic. It mediates its actions throught k-opiod receptor, and to a lesser agree d2. It has zero action on serotonin, which all classical psychadelics exhibit.

That being said, there are few and far between anecdotes you can find for salvia improving mental clarity or alertness. The maps study could be called hardly scientific. All they did was gauge the effects at a certain dose of leaf, and leaf varies widely in potency meaning every single person in the study took a different amount of the active.

The vast majority of reports people make on Salvia are vastly negative; and the actions described by people are hardly what we're seeking. Most people are beset by amneisa, lack of focus, short term memory impairment, uncoordinated motor functions, out of body experiences, uncontrollable laughter, new and disorganized thought patterns.

Edit; Maybe total disruption of working memory and the subsiquent glide down to baseline leaves the user with less background mental chatter/worry/stress, leading to a feeling of being alert, and allowing the mind to focus in a more linear and single fashion instead of layers of interpretation.

Edited by branks, 16 March 2013 - 09:15 PM.

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#67 vali

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Posted 17 March 2013 - 05:54 PM

Yeah, you're right. Saliva isn't much use as a nootropic. Oh well.

#68 branks

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Posted 17 March 2013 - 07:41 PM

Your heart was in the right place. :p

#69 Raza

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Posted 21 March 2013 - 06:52 PM

Wanna link to those BNOME-cases you're citing?

You can't take drug scares at face value, ever. Doing your own reading is the only way.
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#70 mission780

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Posted 22 November 2013 - 05:45 PM

Anybody have experience with 2-CD. Those anecdotes were awesome, MeDieViL.

Too bad I react very bad to 5-HTergic psychedelics now. I seem to have some kind of bad sensitization to them. LSD and 4-AcO-DMT no longer agree with me.


Tried 2C-D in small doses (3-10mg). Felt: nice stimulation, mood improvement, more energy and faster thinking which might be considered as a nootropic effect, I suppose, although not quite cognitive enhancement that happens on very low doses of LSD.

#71 mission780

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Posted 22 November 2013 - 05:57 PM

Yeah being carefull is important, im waiting to experiment mostly with my 5 meo dipt and cannabinoids till i have a working scale again, some things like 5 meo dalt are more forgiving and its possible to eyeball them.


Cannabinoids (I am referring to Cannabis Sativa mainly) - definitely more creative thinking, more out-of-the-box associations, great ability to emphatize (esp. imagine/put oneself in sb's place) as well as the ability to kind of 'feel' theoretical concepts, to 'feel' ideas.

#72 Colour

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Posted 22 November 2013 - 11:11 PM

Low dose ibogaine
No1 in this thread has talked about it.


Low dose 2ci did not increase my anxiety and motivated me.

#73 mission780

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Posted 23 November 2013 - 08:00 AM

Low dose ibogaine
No1 in this thread has talked about it.


Low dose 2ci did not increase my anxiety and motivated me.


Does low dose 2C-I "only" influence mood and motivates? Is there any cognitive enhancement with it, too?

#74 Colour

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Posted 23 November 2013 - 05:20 PM

I had only tried low dose 2c-i once. Some congition boost though. I was more open to flowing ideas. Things were easier.
Not as much boost as a racetam.

Edited by Colour, 23 November 2013 - 05:21 PM.


#75 mission780

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Posted 23 November 2013 - 06:05 PM

I had only tried low dose 2c-i once. Some congition boost though. I was more open to flowing ideas. Things were easier.
Not as much boost as a racetam.


May I ask which racetam gave you bigger cognition boost than the 2c-i?

#76 Colour

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Posted 23 November 2013 - 06:20 PM

It's hard to say which racetam gave me a bigger boost than low dose 2c-i. I meant the way I mix all the racetams (ani- oxi- prami-) gives me a better boost than when low dosing 2ci
I would have to try out lumosity games while on something like (25c probably nowadays).

#77 mission780

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Posted 24 November 2013 - 01:56 PM

Does low dose 25c have similar cognitive enhancement effect to low dose LSD?
How is its tolerance? Is it a bad as LSD tolerance?

#78 Colour

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Posted 24 November 2013 - 02:01 PM

Tolerance/enhancement = same
How are your trial runs with cognitive enhancement on any size dose of psych's?

Edited by Colour, 24 November 2013 - 02:01 PM.


#79 mission780

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Posted 24 November 2013 - 10:33 PM

Tolerance/enhancement = same
How are your trial runs with cognitive enhancement on any size dose of psych's?


Low dose LSD (20-40mcgs, but also medium dose - up to 70mcgs) is the best one - it has all the properties I am looking for - clear reasoning, faster thinking, greater creativity, mood and motivation boost, wide perspective on things, better problem solving skills. The only problem is this terrible tolerance which makes daily use of LSD practically impossible. It can be done every 3 days very effectively.

Small amount of marijuana is also great. It boosts creativity, improve verbal and written skills. I also noticed that weed (also LSD) makes me more aware of my feelings/emotions/thoughts and helps me express them in a much more precise way. And the good thing is that weed can easily be used even on daily basis and it will almost always work, although 1-2 days off is very recommended to increase its effects again.

What I don't like about weed is that is seems to be very subjective. I am not always sure if my ideas/conclusions are reasonable and practical under the influence of marijuana. With LSD, I have exactly an opposite impression - my ideas most of the time are very practical, reasonable and I feel motivation to pursue them.

2C-D - the alleged nootropic hasn't done much for me. I've tried it only a few times recently and at low doses (4-10mg). Apart from stimulation (faster thinking) I haven't noticed any cognitive enhancement, maybe even opposite - some kind of 'foggy' thinking.


Do you have any interesting experiences with psychedelics in this regard yourself?

Edited by mission780, 24 November 2013 - 10:37 PM.


#80 Colour

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Posted 25 November 2013 - 05:12 AM

nah I'll have to experiment

#81 Ark

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Posted 25 November 2013 - 09:40 AM

Anyone taken low does LSD before low intensity work outs? (EXAMPLE) Tai Chi.

#82 mission780

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Posted 25 November 2013 - 11:02 AM

Anyone taken low does LSD before low intensity work outs? (EXAMPLE) Tai Chi.


I tried lower and medium doses (20-70mcgs) with cycling or walking or some smaller exercise at home and it's great! LSD is also boosting physical side and body activities that involve movement/exercise go perfectly with it!

I don't know about Tai Chi, if it's too slow, you might become a little impatient with medium doses, but with low ones it should be good.

#83 mission780

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Posted 25 November 2013 - 02:24 PM

Can anybody please advise me regarding cutting/dividing LSD blotters in order to get a lower dose that is quite precise.

Are LSD blotters covers with acid evenly on the whole surface? For example, if I had a 100mcgs blotter and split it into two exact halfs,
can I be sure each one of them will be 50mcgs. And a quarter of blotter will be 25mcgs?

I don't know the technique of producing blotters. I've always assumed the (blotter) sheet is being soaks in liquid LSD. If it is so,
the acid should be evenly spreaded on each blotter and the technique of cutting blotter into smaller pieces should prove precise enough
to get the right amounts of low doses. Or am I making a mistake somewhere?

Or there is a better way of getting precise low doses from LSD blotter? Would dissolving LSD blotter in (refrigerated distilled) water work better?

Edited by mission780, 25 November 2013 - 02:24 PM.


#84 Colour

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Posted 25 November 2013 - 07:36 PM

Are LSD blotters covers with acid evenly on the whole surface?
YARR matey that be true!
They soak blot in liquid usually, you know how if you put a drop of dye in a pool it spreads like wildfire

#85 mission780

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Posted 25 November 2013 - 10:51 PM

Are LSD blotters covers with acid evenly on the whole surface?
YARR matey that be true!
They soak blot in liquid usually, you know how if you put a drop of dye in a pool it spreads like wildfire


I can imagine that.
Anyway, some people claim that sometimes acid may not be evenly distributed on the blotter sheet due to different drying techniques.
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#86 Virtual Reality

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Posted 25 November 2013 - 11:24 PM

Low doses of DXM might help, im taking about 50-100 mg
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#87 Colour

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Posted 26 November 2013 - 06:09 AM

alex921, after trying out an SSRI for a week 2 years ago I am unable to reap any euphoria from any of MDMA's many analogues. DXM normal doses are not profitable anymore.
I find this strange and abnormal. 5-htp still has effects.
Will low-dose dxm be beneficial to my state of mind?

#88 Virtual Reality

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Posted 26 November 2013 - 11:45 AM

Im not quit sure if it will work out for you, all I know is DXM is pretty potent for anxiety. The problem is with DXM , it can make your problems worse. So I dont advise taking it.
But at a dose of 100 mg , its seems pretty harmless.. Anyone agrees?
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#89 mission780

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Posted 03 December 2013 - 04:54 PM

Are LSD blotters covers with acid evenly on the whole surface?
YARR matey that be true!
They soak blot in liquid usually, you know how if you put a drop of dye in a pool it spreads like wildfire


Hopefully it is that evenly spread as you say. I've heard that during the drying process of blotter sheets, if they use vertical position for drying the bottom might have more of the substance than the top. But maybe it's just a gossip that isn't true at all.

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#90 almostalwaystired

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Posted 03 December 2013 - 06:58 PM

Be careful making any blanket statements about salvia. Speaking experientially, its action varies wildly according to dosage and delivery method (e.g., even changing the kind of lighter you use, for example, using a hotter torch lighter, while smoking it, is subjectively completely different than using a basic bic.) The vast majority of "popular" salvia reports will be from smoking it, and probably not it but rather its extract, with a lighter.

Personally, eating the leaves has been a fundamentally different experience. It's wonderful and beautiful and soothing rather than an erratic (sometimes amazing and beautiful, often terrifying) ego-death experience.

I wouldn't consider either to be nootropic in any way except that there is a several hour afterglow after smoking it that I found more useful than the peak experience itself. There was an overall sense of well-being: brighter colors, increased energy, improved motivation, lucid thoughts, etc. It's been years since I used it, but for the last dozen or so experiences I was dealing with the "blast me into cosmic space" part of the smoking high for the purposes of getting to the quite euphoric/energizing afterglow.

That said, the afterglow for many would be considered more recreational than nootropic. But, in this thread, at least, I think it makes sense to mention it.

Edited by almostalwaystired, 03 December 2013 - 06:59 PM.

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