I posted a few studies That show that C60 elevates TNF-a, an inflammatory marker.
Those studies used a polyhydroxylated c60, a fairly different animal from the c60 that we're using, which has a couple fatty acids linked to it, but is otherwise more like pristine c60. Because of the involvement of ROS in chronic (but not short term) inflammation, we might expect it to act as something of an anti-inflammatory, in certain conditions.
The first time I stopped taking c60, I felt like I was going through a withdrawal syndrome, with higher levels of inflammation in general. This started about a week or ten days after taking 6mg total over four days. At the moment, I'm in my second off period, nine days out from a week of 2.5mg/day. If there is to be a withdrawal syndrome, it's not happening yet. Based on the first experience, I'd expect it to take another one to three weeks, but we'll see. It's always possible that my initial "withdrawal" sensations were colored by a couple injuries that I'd sustained. I'll just have to see how it goes this time around.
edit- Just to be clear, I never felt any pain while I was taking c60-oo; at least not that I could attribute to c60.
Edited by niner, 06 December 2012 - 12:43 AM.