Soy lecithin contains phosphatidylcholine.
Choline and soy lecithin have almost the same benefits as to memory, skin, etc...
Yes you can take too much if you mix the three, it will cause SLUDGE syndrome, if you don't OD it will cause unpleasant symptoms such as polyuria, extreme gas, bowel movement, darkening of vision (due to miosis).
Phosphatidylcholine has a long half life (20-24h) so you wouldn't take it everyday if you were to mix cholinergics.
To me 15g soy lecithin and 500mg choline is already too much and cause SLUDGE.
Not to disparage but to be honest, your post is inaccurate and when wrong information is presented as right information it can be dangerous.
To begin, let's talk about lecithin. It's a relatively non-specific catch-all word meant to describe yellowish fats that occur in biology--most frequently in eggs, soybeans, and other seeds and things. As such, lecithin is actually composed of many molecules, and phosphatidylcholine is one of them. On this part, the quoted material is fine.
Phosphatidylcholine (PC), meanwhile is a phospholipid. It is a long skinny molecule with two chemically distinct termini. On one end is the fatty part (the "phosphatidyl" contributor). On the other end is a non-fatty part (the "choline" contributor). The difference between PC and phosphatidylserine (PS) is a mere swapping of the non-fatty choline for serine. PS and PC are part of the surfaces of every cell in your body. They are called glycerophospholipids, and these are essential building blocks for building the lipid bilayers that surround every cell to define those cells' insides from their outsides.
Taking these things--even with choline on top--cannot and will not cause "SLUDGE syndrome." SLUDGE syndrome is a specific type of neurologic and hormonal dysfunction that happens when a person's "parasympathetic system" is critically hyperactive. It tends to involve over-production (or under-degradation) of a neuro-chemical called acetylcholine. And, sure, acetylcholine is derivative of choline. But your body doesn't use everything you put in it. And your neurons are not going to make too much acetylcholine simply because their body ate too much choline.
Nerve gases cause SLUDGE syndrome; causing SLUDGE syndrome was the goal when many nerve gases were developed. Certain Alzheimer's drugs or other drugs (especially in overdose), including some fertilizers and insecticides cause SLUDGE syndrome. Taking an over-the-counter supplement is
sensationally unlikely to cause SLUDGE syndrome.
To the OP, what is more likely if you take all 3 of these things, your cells and body may (or may not) be negligibly healthier, but what those cells/body don't need in a normal day in terms of lecithin and PS will be stored as very expensive body fat and what those cells/body don't need in a normal day in terms of choline will be expelled as very expensive urine. There is no evidence these things improve cognition. Only the circumstancial evidence that these molecules just so happen to exist in the brain. But they also appear in every other tissue.
Edited by dudekd, 22 January 2014 - 04:39 PM.
