#301
Posted 07 April 2013 - 06:14 PM
#302
Posted 07 April 2013 - 06:16 PM
#303
Posted 07 April 2013 - 06:49 PM
I am new to this forum but a long time lurker... I have read up to page 9 of this thread so far,just cannot wait for the package to arrive! Speaking of caffeine,I was at the verge of death once due to OD.
You see, I used to take caffeine for it's stiumaltory effects which helps in weightlifting.
BUT all that changed on one occasion I went total OTT(a table spoon of it alongside Beta-alanine/Taurine/monohydrate creatine). I had roughly a tablespoon of it.
I felt a different kind of "high"/nothing psychedelic like, just hyper,more talkative,full of energy when I was on it.
It came to the point where I was constantly throwing up, to the point where I was severely dehydrated,so I was taken to the ER.I had all of the symptoms of OD with the exception of a heart attack.
I was told to stay off any kind of supplement for at least 3 weeks,since my creatinine levels were x400 times higher than normal,no suprises there since I was lifting for 3 hours straight prior to the worsening of my condition.
To cut long story short (which this isn't): Never underestimate stimulants of any kind. My caffeine intake used to be non-existent before supplementation,within 4 months I went from 0mg up to 1g. lol
It has been six months since that day, I have come out clean...
Now coming back to what I read few pages back about a member taking high doses of caffeine.I am not surpised at all, it's very probable that high dose caffeine was the cuplrit,since it stimulaes sympathetic nervous system that in a chain of reaction relases Ach,not to mention "the flight or fight response"/ a response that the human body uses as "last resort".
P.S :Such high doses most likely alter our brain physiology.I panic too easily nowadays since that incident.
#304
Posted 07 April 2013 - 07:08 PM
DO NOT TAKE OVER 100MG DO NOT TAKE OVER 100mg
- one teaspoon caffeine anhydrous
Sounds good.
............
i will do this :
10
20
40
80
150
i am stopping caffeine no xplode hydroxycut taurine and creatine, i will try on monday
i only keep the fish oil
One teaspoon of caffeine? Is this something you do regularly? That's an insane amount of pure caffeine. Foolishly, I took a quarter teaspoon of caffeine without weighing it about 2 years ago and had a pretty severe reaction. IIRC that was nearly 1,000mg of caffeine on top of what I usually consume in energy drinks. If this was your first time taking that much caffeine I'd guess it as the culprit.
But as far as working your way up to 150mg of sunifiram... why would you want to do that? I really don't understand why the goal is to take large amounts of this stuff. Isn't the whole point of the shulgin method to find a safe effective dose when working with untested compounds?
Personally I think it would be more prudent to start somewhere around 2mg and work up from there each day. Find an effective minimum dose and keep it somewhere around that level. If 5-10mg is working why take 100-200mg?
#305
Posted 07 April 2013 - 07:41 PM
Last night: 5:45a bedtime / 10:35a WIDE AWAKE: Total = 4 hours 50 minutes.
Normal requirement = 8.5 - 9 hours sleep.
75% Sustained reduction in sleep requirement in two days of therapeutic use with better clarity upon awakening and no more daytime sleepiness.
That 75% reduction in sleep requirement is not from baseline but the result of transitioning directly from the most powerful tested stack of Piracetam 5gx6 + Pramiracetam 300mgx6 daily for prevention of daytime sleepiness and increase in sleep-quality.
75% Better at sleep quality improvement and 100% better than that powerful racetam stack at preventing daytime sleepiness.
And that is from testing since Summer 2008 these nootropics in high doses, alone and stacked:
Piracetam
Aniracetam
Oxiracetam
Nefiracetam
Phenylpiracetam
Pramiracetam
Noopept
Sulbutiamine
Finally, wurm's report that Caffeine was potentiated to the extreme (in his case largely due to tolerance combined with very large intakes) but only when Sunifiram dose was escalated from the 10mg range to the 100mg range indicates that Sunifiram has stronger effects at least up to 100mg/dose, and those effects may be very powerful.
I hope other individuals can test at least the 55mg area and hopefully a few tries at 100+mg.
#306
Posted 07 April 2013 - 07:57 PM
Edited by Megatrone, 07 April 2013 - 07:58 PM.
#307
Posted 07 April 2013 - 08:14 PM
I watched it too - in HD - and found it to be quite amazing.
The movie was based on Modafinil, which unlike the fictitious NZT-48 has real side-effects and tolerance, and is a stimulant not a nootropic.
As for NZT's real-life formulation, I suggest trying 100mg x 6 per day of Sunifiram stacked with 200mg Modafinil in the morning or early afternoon.
The one thing missing from Sunifiram is the nice speedy stimulated effect at least in my experience thus far. It's a very clean, totally 'quiet' nootropic. So it would go well with a minimal dose of something that adds fuel to the fire. I'm running in lean-burn mode now so I have no idea how really powerful the Sunny catalyst might be because I have little fuel in my fire.
Edited by Isochroma-Reborn, 07 April 2013 - 08:15 PM.
#308
Posted 07 April 2013 - 10:12 PM
Normally I wake up about six times per night but for the first time in unknown years last night I slept with only about one waking.
Dreaming was at reference level.
It seems that - as another poster commented - Sunifiram consolidates sleep in addition to improving its quality.
#309
Posted 08 April 2013 - 01:02 AM
@Isochroma
You said you take 5F-AKB-48 regularly. May I ask why? Aren't you worried about its long term effects? It is a synthetic cannabinoid as far as I know, and they are usually demonized.
Edited by therein, 08 April 2013 - 01:02 AM.
#310
Posted 08 April 2013 - 01:11 AM
Works far better than natural cannabis for my chronic insomnia and is much clearer and is legal and is easier on the lungs than the herbal material.
Not to mention costing 2/3 less and not requiring an illegal dealer - mine is delivered in nicely packed envelopes.
No dosing problems nor tolerance issues.
#311
Posted 08 April 2013 - 01:20 AM
#312
Posted 08 April 2013 - 01:32 AM
It also has a highly unbalanced receptor profile which is the equivalent to nearly pure THC without the CBD to moderate its effects and reverse tolerance. Those reports of psychosis, panic attacks and anxiety are due to stimulation of CB1 receptors only without the natural balance of CB2. The JWH series does that.
5F-AKB-48 is one of the best new cannabinoids and far superior to JWH because it has a naturally balanced action at the two receptor sites CB1 & CB2. Activation of CB2 prevents tolerance/withdrawal and also moderates the paranoid effects of pure CB1 activation.
Finally, like any intelligent drug user I buy my molecule pure from a reputable source rather than taking some 'spice' mix, etc. Starting pure means never getting suprised by an unexpected increase in purity.
Having a milligram scale and long experience measuring and using potent molecules means that I don't make stupid mistakes.
Not combining it with alcohol or other actives that can alter its metabolism, nor taking it more than once a day or obtaining dubious material from others are also safety features of my regimen.
All these factors meant I was able to transition flawlessly two months ago from over fifteen years of the plant material to 5F-AKB-48 with absolutely zero problems.
Edited by Isochroma-Reborn, 08 April 2013 - 01:36 AM.
#313
Posted 08 April 2013 - 01:41 AM
The JWH series is now illegal in most of the world's countries.
It also has a highly unbalanced receptor profile which is the equivalent to nearly pure THC without the CBD to moderate its effects and reverse tolerance. Those reports of psychosis, panic attacks and anxiety are due to stimulation of CB1 receptors only without the natural balance of CB2. The JWH series does that.
5F-AKB-48 is one of the best new cannabinoids and far superior to JWH because it has a naturally balanced action at the two receptor sites CB1 & CB2. Activation of CB2 prevents tolerance/withdrawal and also moderates the paranoid effects of pure CB1 activation.
Finally, like any intelligent drug user I buy my molecule pure from a reputable source rather than taking some 'spice' mix, etc. Starting pure means never getting suprised by an unexpected increase in purity.
Having a milligram scale and long experience measuring and using potent molecules means that I don't make stupid mistakes.
Not combining it with alcohol or other actives that can alter its metabolism, nor taking it more than once a day or obtaining dubious material from others are also safety features of my regimen.
All these factors meant I was able to transition flawlessly two months ago from over fifteen years of the plant material to 5F-AKB-48 with absolutely zero problems.
Sounds like you're on the safe side of things. I don't get why people get those 'spice' mixes either. You would never know what you're getting.
I don't intend to transition from plant material but synthetic cannabinoids are definitely interesting.
#314
Posted 08 April 2013 - 02:17 AM
The Law has funny ways of changing intentions into necessities and so does losing your dealer.
Now though I would never go back even if it were not for the things that pushed me to adopt my current regime.
#315
Posted 08 April 2013 - 03:44 AM
DM-235 = NZT-48 = Modafinil 2.0
Ha! Well maybe when stacked with zembrin/ciltep. Hmm.. I think I'll go try that now. Will start with 5mg. Took zembrin/ciltep this morning and am definitely feeling it now. Wheee......
Edited by abelard lindsay, 08 April 2013 - 04:20 AM.
#316
Posted 08 April 2013 - 03:53 AM
5mg is very low so don't expect to feel anything.
#317
Posted 08 April 2013 - 03:59 AM
No stacking needed. I threw out my old stack and am on just Sunifiram 55mg x 6 / day.
5mg is very low so don't expect to feel anything.
Ahh man you gotta try Zembrin + Forskolin. Zembrin is the first high potency, non-emetic, selective PDE4 inhibitor that any normal mortal could get his hands on. Adding Sunifram to this for CAMKII and Ampa activation completes the learning/memory pipeline, well except for NMDA but nobody knows how to fix that except for long-term Magnesium Threonate use.
Edited by abelard lindsay, 08 April 2013 - 04:20 AM.
#318
Posted 08 April 2013 - 04:06 AM
#319
Posted 08 April 2013 - 04:08 AM
Today I went hiking with my friends up at Mt. Charleston - Mary Jane Falls. I took 1.8g Piracetam and 1.6g of Choline (no sunifiram that day) and I can say that the effects of Piracetam were amazing which I didn't have before. Keep in mind I stopped taking Piracetam about 2-3 weeks ago. Maybe it's the 2-3 week break that's helping the Piracetam, but damn I had so much focus and energy.
EDIT: Thanks Iso!
Edited by emckai, 08 April 2013 - 04:34 AM.
#320
Posted 08 April 2013 - 04:32 AM
#321
Posted 08 April 2013 - 04:36 AM
#322
Posted 08 April 2013 - 06:23 AM
There isn't much to do tomorrow, I have only one class tomorrow which is at 8:30am and after that I'll just head over to the library and get some work done.
Wish Fall semester would come faster, I'll be changing my major from Computer Science to Biochemistry. Not sure if I'll be making a complete change, but i'll be taking some biochem courses to get the feel for it.
#323
Posted 08 April 2013 - 09:02 AM
#324
Posted 08 April 2013 - 03:45 PM
i took a chunk of sunifiram, i don't know how much i was kinda lazy and just eyeballed the stuff
i have an heightened sense of perception and feeling in balance with my environment, feels good, so far so good no sweating no heart going berserk
wasn't that after all but caffeine but this is dangerous guys, really who doesn't take a morning coffee? almost everyone does and this freaks me out, this stuff is too potent or maybe was it the combination of high dose sunifiram dunno
i still have damage from that other night, my cardiovascular system doesn't seem right, it hurts in my vessels sometimes, the doctor said it was because of alterd blood flow but didn't give me anything to solve this, i guess this is a lesson
#325
Posted 08 April 2013 - 04:27 PM
wasn't that after all but caffeine but this is dangerous guys, really who doesn't take a morning coffee?
It's important to keep in mind that it is not established that sunifiram potentiates caffeine to any noticeable degree, especially at typical dosages, which seem to be 5-10 mg, not the 100+ mg megadoses that a few have experimented with. In your previous post, you said you took a teaspoon of caffeine. Caffeine has a density of 1.23 g/mL * 4.92 mL (ie one teaspoon) = 6 g.
Six grams of caffeine is a ton. You could literally overdose on that without mixing it. The fact that you mixed an absurd amount of caffeine with sunifiram does not mean that sunifiram is harmful. (Although I'm still not entirely comfortable with it since positive allosteric modulation at the AMPA site has some potential for excitotoxicity depending on a number of variables.)
#326
Posted 08 April 2013 - 09:49 PM
#327
Posted 08 April 2013 - 10:22 PM
Sounds like Sunifiram is working well for you.
It continues to work well for me too:
Last Night:
Bed: 6:30a
Wake: 10:30a
Slept Hours: 4
#328
Posted 08 April 2013 - 11:29 PM
No stacking needed. I threw out my old stack and am on just Sunifiram 55mg x 6 / day.
5mg is very low so don't expect to feel anything.
I trust you Isochroma. Once I get home, i'll try 55mg of Sunifiram along with about 200mg of Choline Bitartrate.
#329
Posted 09 April 2013 - 12:00 AM
And when I said no stacking needed I just meant that the effects are for me strong enough on their own that it doesn't need to be stacked - however, stacking will undoubtedly be the Next Big Project as we learn about Sunifiram's effects alone first.
#330
Posted 09 April 2013 - 12:07 AM
I fear taking too high of doses because I believe it will probably create some mania. Its working at 15-20 mg doses now anyway so why waste it and take more. Its more than likely just gonna cause damage to brain and wallet. Although by damage I don't mean anything extreme but mainly just cause a burnout or some memory problems..
A few people mentioned being burnt out and taking a break.. Could any of you explain a little more what happend if you have some time?
Also tagged with one or more of these keywords: sunifiram
Science & Health →
Brain Health →
Mental Health →
Sunifiram and IQStarted by ketogeniclongevity , 29 May 2017 sunifiram, nootropic |
|
|
||
Science & Health →
Brain Health →
Stack for Focus, Mental Clarity, Depression, and Crohn's?Started by Sweet Potato , 13 Apr 2017 crohns, depression and 8 more... |
|
|
||
Science & Health →
Brain Health →
Getting Back ON TrackStarted by Q did it! , 16 Aug 2015 nootropic, smart drugs, sunifiram and 7 more... |
|
|
||
Science & Health →
Brain Health →
Mental Health →
How do i reverse the damage from Sunifiram?Started by Coffeee , 23 Jun 2015 sunifiram |
|
|
||
Science & Health →
Brain Health →
Sunifiram - headacheStarted by Zajk , 18 Jan 2015 sunifiram, headache |
|
|
47 user(s) are reading this topic
0 members, 47 guests, 0 anonymous users