1565 replies to this topic

[MizTen]

Hey Isochroma you may want to look at this http://psychcentral....-manic-episode/.

I have reason to believe I may be having a manic episode for a little over a week. The orientation of my persona has seemed to have shifted very noticeably, upbeat mood need for less sleep, I awaken full of energy, increase in libido and many other things have changed since I have added Suni to my stack. I am not sure if the effects are good, I feel much better on this stack than any other I have devised but am questioning whether I really am any better? Or is this some kind of mirage cast by the Sunifiram? I am starting to worry about Sunifirams unknown side effects.

Those effects should reasonably be of some concern. Sunifiram is not difficult to stop taking, What doesn't feel healthy is probably not healthy. Maybe time to give your brain a rest...

Just my 2 cents.

[peakplasma]

Hey Isochroma you may want to look at this http://psychcentral....-manic-episode/.

I have reason to believe I may be having a manic episode for a little over a week. The orientation of my persona has seemed to have shifted very noticeably, upbeat mood need for less sleep, I awaken full of energy, increase in libido and many other things have changed since I have added Suni to my stack. I am not sure if the effects are good, I feel much better on this stack than any other I have devised but am questioning whether I really am any better? Or is this some kind of mirage cast by the Sunifiram? I am starting to worry about Sunifirams unknown side effects.

If you feel manic there is a good chance you might be. Anecdotal experiences suggest racetams seem to precipitate manias even in people otherwise not predisposed to mania. And considering Sunifiram's potency I wouldn't be surprised if this was happening to you.. try lower doses if you can or start to taper down and stop for a bit.

You definitely would not be the first person to get mania from racetam use.

Edited by peakplasma, 03 May 2013 - 05:31 AM.

[OpaqueMind]

Is mania inherently a bad thing?

[peakplasma]

Is mania inherently a bad thing?

Coming down from a mania or hypomania can be quite bad.

[golden1]

Isochroma you sound a bit crazy.. again. you're getting these effects from an already high dose, now you want to multiply the intake by 5? okaaaaaaaaaaaaaaaaaaaay.

Edited by golden1, 03 May 2013 - 12:10 PM.

[pkstrl0rd]

Hey Isochroma you may want to look at this http://psychcentral....-manic-episode/.

I have reason to believe I may be having a manic episode for a little over a week. The orientation of my persona has seemed to have shifted very noticeably, upbeat mood need for less sleep, I awaken full of energy, increase in libido and many other things have changed since I have added Suni to my stack. I am not sure if the effects are good, I feel much better on this stack than any other I have devised but am questioning whether I really am any better? Or is this some kind of mirage cast by the Sunifiram? I am starting to worry about Sunifirams unknown side effects.

If you feel manic there is a good chance you might be. Anecdotal experiences suggest racetams seem to precipitate manias even in people otherwise not predisposed to mania. And considering Sunifiram's potency I wouldn't be surprised if this was happening to you.. try lower doses if you can or start to taper down and stop for a bit.

You definitely would not be the first person to get mania from racetam use.

I thought Sunifiram wasn't considered a racetam?
Only the affects are racetam like, right?

[golden1]

It doesn't really matter what it is classified as -racetam or whatever, the actions it has on the body/brain are what matter and we barely know what the full extent of these actions could be.

Also q that sounds like a very mild form of mania, you have to decide I'd say: is seemingly mild hypo-mania a negative or a positive.. hard to say, but I think it just gives more reason to be careful and if you notice it getting worse or get a strong rebound effect you probably want to stop.. or force yourself to get more sleep(easier said than done, but..) which might solve any mania-type feelings.

Edited by golden1, 03 May 2013 - 01:49 PM.

[pkstrl0rd]

I'm only worried because if it's a racetam it's not legal to bring into my country.
Didn't mean to be bitchy or anything.

[health_nutty]

I'm getting better results from 10mg TID rather than 20mg TID. At 20mg TID I start to get the all too familiar "brain fog" from overdoing racetams. It feels something is geting depleted (even with sufficient Ach precursors). The reason I say this is because I feel great while the racetam is in peak effect (2-3 hours), BUT as it wears off I feel light headed and slightly spacy. Anyone want to take a guess on what is getting depleted? I happens more with Aniracetam and Sunifiram and somewhat with noopept (at the higher dosage range).

Edited by health_nutty, 03 May 2013 - 03:31 PM.

[health_nutty]

Let me add my 2 cents: I believe the brain fog from too high of dosage may be related to too low of glucose in the brain. The brain fog will partially go away if I have some sugar. For health reasons I try to avoid sugar, but I have plenty of starch from gluten free grains such as black rice, whole oats, quinoa.

[renfr]

I could buy 200g sunifiram on sun nootropic and then sell it $15 free shipping per gram, anyone interested?

[golden1]

I'm only worried because if it's a racetam it's not legal to bring into my country.
Didn't mean to be bitchy or anything.

It depends what the law says, what is the wording of the law? no -racetams? seems pretty odd..

[pkstrl0rd]

I'm only worried because if it's a racetam it's not legal to bring into my country.
Didn't mean to be bitchy or anything.

It depends what the law says, what is the wording of the law? no -racetams? seems pretty odd..

Piracetam and Oxiracetam are prescription medicines here and illegal to import because of that. Any other member of the racetam family (Noopept counts) is also illegal because of the link to those substances.

[golden1]

I'm only worried because if it's a racetam it's not legal to bring into my country.
Didn't mean to be bitchy or anything.

It depends what the law says, what is the wording of the law? no -racetams? seems pretty odd..

Piracetam and Oxiracetam are prescription medicines here and illegal to import because of that. Any other member of the racetam family (Noopept counts) is also illegal because of the link to those substances.

that's whack especially if noopept counts. I don't see how the law could be worded to catch them all like that... unless it considers any prescription medicine anywhere illegal to import, in which case I guess sunifiram would be legal to import. also it doesn't have a pyrrolidone ring in it like -racetams and noopept, seems odd there would be a law against chemicals w/ pyrrolidone rings tho.

[Isochroma]

As I expected, New Star Nootropics is watching this thread

Today - the day after I announced the availability of cheap bulk Sunifiram from Sun Nootropic, New Star Nootropics has lowered their prices.

Their new prices are listed in today's Racetam Prices list {Ver. May 3.1 2013}.

[Amorphous]

I am considering to even lower my dose of 5-10 mg of sunifiram from once daily for 5 days per week to once daily for 3-4 day per week due to the possibility of manic reaction. In my first week of using Sunifiram, I've tried to use 15-20 mg 2 x daily due to stress from work. I felt like it helped me deal with the problems I was facing pretty effectively - at least in a sense that I was more confident and a little more creative. However, I also sensed something not quite right and I received comments from co-workers that I was little over-eager in my behaviors and little aggressive in my approach to solve problems. Sometime it just needs someone else to point it to me about myself before I realize there is something going wrong. After I cut back to 5-10 mg, things seems better.

Edited by Amorphous, 04 May 2013 - 03:42 PM.

[Bismarck]

that I was little over-eager in my behaviors and little aggressive in my approach to solve problems.

Good point. I found that I also became more agressive with people in certain situations. However in general my goodwill towards people is much improved.

Also be carefull not to put too much wheight on your coworkers opinion. Overeagerness has a pretty bad ring to it, how about imrpoved motivation instead? You should judge yourself by the quality of your work and not how your coworkers percieve you.

[Amorphous]

that I was little over-eager in my behaviors and little aggressive in my approach to solve problems.

Good point. I found that I also became more agressive with people in certain situations. However in general my goodwill towards people is much improved.

Also be carefull not to put too much wheight on your coworkers opinion. Overeagerness has a pretty bad ring to it, how about imrpoved motivation instead? You should judge yourself by the quality of your work and not how your coworkers percieve you.

That is true. It also important to make sure the experimental drug we are using does not affect our judgement. Since Sunifiram is a compound affecting brain biochemistry in a way no one knows exactly how it works, it may affect our own judgement without we even aware of it. It is important to establish some type of benchmark to signal the deviation of our normal self. Someone you can trust is a good start.

[golden1]

felt like this was worth sharing:

The day after I was dosing for about a week @ 10-20mg twice a day I decided to take a psychedelic, 2C-E, which I've taken many times. It always had this incredibly uncomfortable undertone to it, nausea, internal jittery feelings, inability to be fully comfortable, etc. I put up with those effects because it's an amazing psychedelic otherwise. Now this time I got very very subtle side effects in comparison when I took it and the visuals were comparable to the first time I did a psychedelic(yeaars ago). It went from being euphorically beautiful yet tense and annoying... to euphorically beautiful and serene. Not sure what to make of it... I'd think NMDA/AMPA potentiation would make sideeffects worse, but now I remember that piracetam also helped with the side effects... not anywhere near as much as sunifiram, but it did help.

I also notice that it feels like my tolerance to benzos is lowered, not that I feel more drugged, but that the dose I'm down to at the moment feels adequate instead of slightly lacking.

Nefiracetam did a similar thing with the benzo tolerance, but afaik it is known to effect GABA, so it was more expected.

[Isochroma]

Finally!

Your contribution is the world's first report of combining Sunifiram with a psychedelic

The World thanks you and I say: Sunifidelic!

Now I eagerly await a report of Sunifiram combined with MDMA.

Regarding my sleepcycle: last night's bedtime was 3:30a and I woke naturally well-slept at 8:22a - five hours while my normal before Sunifiram was average 8.5h. I never sleep more than six hours any more and the average has been 5.5h.

Yet I am also never sleepy during the day anymore either!

Thus I conclude that my sleep quality has improved enormously.

Edited by Isochroma-Reborn, 05 May 2013 - 08:21 PM.

[MangekyōPeter]

I'll have a Sunifiram combined with Psilocybin experience to report tomorrow.

[Dissolvedissolve]

Now I eagerly await a report of Sunifiram combined with MDMA.

Keep in mind that someone nearly overdosed combining sunifiram and caffeine. Now that was a megadose of caffeine, but I still don't think it's wise to be recommending a combination with MDMA.

Honestly, even combining it with psychedelics is a bit sketchy at this point. Although classical psychedelics have been shown to be safe when used by themselves, there's evidence that they can combine poorly with other substances. For instance, IIRC the 5-HT1A agonism from psychedelics can increase body temperature, thus worsening MDMA neurotoxicity. (Increased body temperature has been shown to increase MDMA neurotoxicity, along with variations in metabolism, with certain metabolites such as MDA being much more harmful than MDMA itself.) Now sunifiram has not been shown to be safe, other than simply in the sense that it doesn't kill people and rats taking large doses, so combining it even with psychedelics seems to be a bit unsafe.

[Cow]

I took 150mg MDMA last night with an earlier dose of Sunifram hanging around and didn't experience any unusual side effects. At the time I never even thought about the combination until I read the earlier posts. The only two things that may have been different were strong colors that were bright, and I felt some stimulant effects lingering around the next morning. I'm positive this was exclusively MDMA, no other stimulant cuts around to cause this. Cannabis smoked the next morning to try and go back to sleep brought back some distinct "rolling" euphoria that felt similar to the night before.

Edited by Cow, 05 May 2013 - 11:27 PM.

[violetechos]

What I really mean is that Sunifiram eternalizes my waking mind.

Also, I am taking some 20mg+ of 5F-AKB48 in the dark right before bed each night.

Just like natural cannabis, this synthetic xenomolecule is an agonist at both CB1 and CB2 receptors and allows me to sleep under the most difficult circumstances.

Don't you think the synthetic cannabinoids are inducing the mania and strange behavior? Full agonism at both CB1 and CB2 is nasty... Perhaps it would be wiser to switch to a purer CB1 agonist? Synthetic cannabinoids tend to induce the strangest self fullfulling mania, just look at the reports of people smoking "spice". So many people are weird and screwed up from that. The saddest part is they don't THINK they are weird from it. I am TOTALLY a cannabis advocate, but the synthetics are so effing creepy.

I understand that you probally believe its neuroprotective, but a wiser idea would be a calcium channel modulator, ideally gabapentin or pregabalin...

If you guys like this, i've some glutamate agonists you will love! LULZ

Anyone wanna buy my sunifiram? 15$ PM me

[therein]

Sunifiram is pretty amazing for alleviating sleep deprivation. Don't get me wrong, I'm not trying to replace sleep or anything but aside from reducing the natural sleep length, it also (as expected) does a great job decreasing the symptoms of sleep deprivation when you don't get enough sleep.

I'm having my finals this week and couldn't get much sleep last night. I woke up feeling awful, took 5mg of Dexmethylphenidate sublingually and that energized me a little. After an hour I took 10mg of Sunifiram and within 15 minutes I was in a much better mood and mental state. It was pretty immediate too. I was looking out of the window and it was almost as if the Sun just got brighter. All of a sudden everything was clearer.

So far I've tried Sunifiram with these without any side effects (not all at the same time):
- Methylphenidate/Dexmethylphenidate
- Amphetamine Salts/Lisdexamfetamine/Dexamphetamine
- Caffeine (not a regular user at all and had no side effects from 200mg)
- Citicoline
- Cannabis
- Alcohol (college binge-drinking amounts)
- ALCAR

Trivial:
- Fish oil
- NAC
- Various vitamins

Edited by therein, 06 May 2013 - 03:13 PM.

[Sun Nootropic]

As I expected, New Star Nootropics is watching this thread

Today - the day after I announced the availability of cheap bulk Sunifiram from Sun Nootropic, New Star Nootropics has lowered their prices.

Their new prices are listed in today's Racetam Prices list {Ver. May 3.1 2013}.

In some sense, Sun nootropic contributes to Sunifiram price for you guys.

Also, i would like to enclose Sunifiram HNMR from sun nootropic.

Attached Files

•  ST-HNMR-314728-85-3-HNMR.pdf   71.46KB   36 downloads

[Isochroma]

Thanks!

I'm planning to buy 50g Sunifiram in a couple months from Sun Nootropic.

[paul]

Think sunifiram has changed me, feel way more confident and intelligent. I have had final medical exams so been through 2.5 grams in 10 days, but also on cerebrolysin so my dose has been high and probably a bit of hypomania but it feels good. I'm sure that like every other medicine (besides memantine / ethylphenidate combo) the feeling won't last but hopefully by then ns1 will arrive. Think maybe 40mg memantine has allowed me to tolerate this dose as no side effects so far, also can't be sure if its more an effect from cerebrolysin which Is has also been lifechanging. I had this effect from piracetam 5 years ago for a few months before it stopped working then gave up on nootropics and only rediscovered them last a few months ago when I started on cerebrolysin. Anyone else had any experiences with a higher dose and how much?

[Passion]

How has Sunifiram continued to work for everyone else involved? Has anyone noticed tolerance building yet like it seems to do for piracetam? How about those who seemed to experience negative effects and tinnitus? Have those persisted? Are you still taking Sunifiram?

[paul]

Think there is tolerance, but little to early to tell, I have been increasing the dose each time as I have got a bit braver, at first was veryncatiousnwith a 20mg but have taken 200mg and also inhaled smaller doses, hmakes you cough. I want to thoroughly test this , and find out tolerance issues and also withdrawal problems, I am prepared for both and accept the unknown side effects, I have been dip sticking my urine and monitoring blood pressure, but still there is a risk as no real human trials, they have tested up to 1mg/kg in mice but no way of knowing the relevant human dose but I'm guessing its higher, no evidence to back this up but we have bigger brains, more synapses and receptors for it to work on. I'm also on memantine so some of my NMDA receptors are blocked, hopefully protecting me from risks of glutamate hyperactivity.