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Lostfalco's Extensive Nootropic Experiments [Curated]

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#961 lostfalco

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Posted 25 September 2013 - 08:44 PM

Why I love it when TULIP helps people and why I'm excited to team up with as many of you guys (many of you will outpace me) as possible in the future to attack the shared problems of ALL humanity: mirror neurons. http://en.wikipedia..../Mirror_neurons If you're a guest reader and experimenting, please join in the conversation! It only took me about 4 years of lurking before I finally shared. ha

http://youtu.be/t0pwKzTRG5E


Not to further derail the thread, but why do you call them "the shared problems of all humanity"?

In my view, the shared problems we all face are diseases, natural disasters, hunger, poverty, misery, suffering etc. I think that those are 'common enemies' to every person on the planet. I just want to work towards helping people enjoy their lives.

For example, I had lunch with my best friend from high school yesterday. He told me that one of his sons (aged 6) is going blind and the doctors don't know how to stop it. He won't be able to see at all within a few years. I told him to send me the data on his son and that I would do my best to either build his son an eye, teach his son's body to rebuild it's own new eye, or find someone who can within the next 10 years. If I can't do it, maybe some of you guys can. To be honest, we are already extremely close and there are currently some options available. Much work still needs to be done, but these sorts of things ARE solvable. The smarter we are and the more smart people we have...the faster we can get there. I think the time has come to stop thinking about other humans as enemies. Call me Polyanna, but we're in this short life together and most of us actually care about other people (there's a percentage that don't). I just want to team up with the people that care and do some cool shit. That's all. =)

Edited by lostfalco, 25 September 2013 - 08:46 PM.

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#962 Strangelove

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Posted 25 September 2013 - 08:53 PM

Any more responses guys? For some seem to work very fast.

Also if you are using the LEDs for a while and do not have an effect, please describe your LEDing schedule, supplements or not, and LED device and adapter.

I do not want to discourage anyone, as I believe I am going to see results eventually, but I am having a 48 LED from ebay, 12V 2.5 Amax, plus Q10 PQQ and approximately LEDing myself 2 weeks now. I started with 2 minutes day by day and today I did only half minute as I believe I was maybe overdoing it. As of now there were some days I was tired and sleepy (even with the side effects, I am happy there is an effect) but nothing positive yet.

If there are individual variations, I would agree with Lostfalco, start very low at first, as it seems very easy to overdose.

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#963 Strangelove

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Posted 25 September 2013 - 08:57 PM

Why I love it when TULIP helps people and why I'm excited to team up with as many of you guys (many of you will outpace me) as possible in the future to attack the shared problems of ALL humanity: mirror neurons. http://en.wikipedia..../Mirror_neurons If you're a guest reader and experimenting, please join in the conversation! It only took me about 4 years of lurking before I finally shared. ha

http://youtu.be/t0pwKzTRG5E


Not to further derail the thread, but why do you call them "the shared problems of all humanity"?

In my view, the shared problems we all face are diseases, natural disasters, hunger, poverty, misery, suffering etc. I think that those are 'common enemies' to every person on the planet. I just want to work towards helping people enjoy their lives.

For example, I had lunch with my best friend from high school yesterday. He told me that one of his sons (aged 6) is going blind and the doctors don't know how to stop it. He won't be able to see at all within a few years. I told him to send me the data on his son and that I would do my best to either build his son an eye, teach his son's body to rebuild it's own new eye, or find someone who can within the next 10 years. If I can't do it, maybe some of you guys can. To be honest, we are already extremely close and there are currently some options available. Much work still needs to be done, but these sorts of things ARE solvable. The smarter we are and the more smart people we have...the faster we can get there. I think the time has come to stop thinking about other humans as enemies. Call me Polyanna, but we're in this short life together and most of us actually care about other people (there's a percentage that don't). I just want to team up with the people that care and do some cool shit. That's all. =)


Could you briefly describe where the issue with his vision is?

#964 Nattzor

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Posted 25 September 2013 - 09:00 PM

Any more responses guys? For some seem to work very fast.

Also if you are using the LEDs for a while and do not have an effect, please describe your LEDing schedule, supplements or not, and LED device and adapter.

I do not want to discourage anyone, as I believe I am going to see results eventually, but I am having a 48 LED from ebay, 12V 2.5 Amax, plus Q10 PQQ and approximately LEDing myself 2 weeks now. I started with 2 minutes day by day and today I did only half minute as I believe I was maybe overdoing it. As of now there were some days I was tired and sleepy (even with the side effects, I am happy there is an effect) but nothing positive yet.

If there are individual variations, I would agree with Lostfalco, start very low at first, as it seems very easy to overdose.


Have you measured the effects or just trying to "feel" it?

#965 seabreeze

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Posted 25 September 2013 - 09:08 PM

LostFalco WTF?

Mannn... Don't you have a job?? (LOL) It is just amazing how efficiently you keep up with this blog. Great job! (hmmm..)

Just a question to anyone... I'm feeling like I need the higher amount of CoQ10 and PPQ (I'm 47 years young). I found this http://www.amazon.co...d=A1NWHVG6ZRL80. I would just need to supp with shilajit which would be just 2 pills a day as opposed to 3-6 (and a little less money).

Anyone familiar with Advanced Orthomolecular Research (AOR)? (If not, I will just go with the Life Extension combo LF mentioned (x2) + 100mg of CoQ10.

Regards,
Seabreeze


#966 Strangelove

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Posted 25 September 2013 - 09:10 PM

No I have not try to measure possible effects, I have tried quite a few mind machines the last 5 years and quite more supplements/drugs, I believe I am really good in judging possible effects, and I was really positive in believing I ll see results (still am, maybe will take longer or change LEDs).

Have you tried it already, anything to share?

Edited by Strangelove, 25 September 2013 - 09:11 PM.


#967 lostfalco

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Posted 25 September 2013 - 09:15 PM

Could you briefly describe where the issue with his vision is?

I'll let you know when I hear. He's gonna e-mail me the info.

Edited by lostfalco, 25 September 2013 - 09:15 PM.


#968 Nattzor

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Posted 25 September 2013 - 09:16 PM

No I have not try to measure possible effects, I have tried quite a few mind machines the last 5 years and quite more supplements/drugs, I believe I am really good in judging possible effects, and I was really positive in believing I ll see results (still am, maybe will take longer or change LEDs).

Have you tried it already, anything to share?


I think too many people measure things subjectively, which may be completely wrong.

I'm currently doing a trail (40 days total in 10 day periods), blinded, to see if I get results.
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#969 AscendantMind

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Posted 25 September 2013 - 09:17 PM

Just a question to anyone... I'm feeling like I need the higher amount of CoQ10 and PPQ (I'm 47 years young). I found this http://www.amazon.co...d=A1NWHVG6ZRL80. I would just need to supp with shilajit which would be just 2 pills a day as opposed to 3-6 (and a little less money).


Looks like that contains regular CoQ10 instead of Ubiquinol, which will probably be a lot less powerful.. Otherwise the dosage amounts are certainly convenient. Doctor's Best PQQ (20 mg) and 300 mg of Jarrow's Ubiquinol could be obtained from Amazon for just $10 more in total (and the Ubiquinol would last you 40 days instead of 30).

#970 lostfalco

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Posted 25 September 2013 - 09:20 PM

LostFalco WTF?

Mannn... Don't you have a job?? (LOL) It is just amazing how efficiently you keep up with this blog. Great job! (hmmm..)

Just a question to anyone... I'm feeling like I need the higher amount of CoQ10 and PPQ (I'm 47 years young). I found this http://www.amazon.co...d=A1NWHVG6ZRL80. I would just need to supp with shilajit which would be just 2 pills a day as opposed to 3-6 (and a little less money).

Anyone familiar with Advanced Orthomolecular Research (AOR)? (If not, I will just go with the Life Extension combo LF mentioned (x2) + 100mg of CoQ10.

Regards,
Seabreeze

Haha...I'm a student now. Have you heard of this guy? =) http://www.utexas.ed...logy/faculty/fg

I haven't met him yet, but I'm gonna try to interview him soon and post a YouTube video. I'll let you know if I do. I'm not sure if I want to show him this craziness though. ha

Edited by lostfalco, 25 September 2013 - 09:57 PM.


#971 AscendantMind

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Posted 25 September 2013 - 09:21 PM

I think too many people measure things subjectively, which may be completely wrong.


Agreed. I want to know for sure if what I am doing works.

I'm not going to do it blinded, since some of the effects could be cumulative and long-lasting (plus the LEDs are very warm--not something I could hide effectively), but I am conducting some assessments before and a month after. Currently going to take the Cambridge Brain Challenge 5 days in a row, then TULIP for a month, then 5 more instances of the test.

I'm relatively new to cognitive self-testing; does that seem like it would be effective or am I totally off-base?

#972 lostfalco

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Posted 25 September 2013 - 09:29 PM


I think too many people measure things subjectively, which may be completely wrong.


Agreed. I want to know for sure if what I am doing works.

I'm not going to do it blinded, since some of the effects could be cumulative and long-lasting (plus the LEDs are very warm--not something I could hide effectively), but I am conducting some assessments before and a month after. Currently going to take the Cambridge Brain Challenge 5 days in a row, then TULIP for a month, then 5 more instances of the test.

I'm relatively new to cognitive self-testing; does that seem like it would be effective or am I totally off-base?

Agreed as well.

I'm gonna do this unless someone with more knowledge gives me a good reason not to. =)
http://drmyhill.co.u...unction_Profile

#973 Keynes

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Posted 25 September 2013 - 09:36 PM

Why I love it when TULIP helps people and why I'm excited to team up with as many of you guys (many of you will outpace me) as possible in the future to attack the shared problems of ALL humanity: mirror neurons. http://en.wikipedia..../Mirror_neurons If you're a guest reader and experimenting, please join in the conversation! It only took me about 4 years of lurking before I finally shared. ha

http://youtu.be/t0pwKzTRG5E


Not to further derail the thread, but why do you call them "the shared problems of all humanity"?

In my view, the shared problems we all face are diseases, natural disasters, hunger, poverty, misery, suffering etc. I think that those are 'common enemies' to every person on the planet. I just want to work towards helping people enjoy their lives.

For example, I had lunch with my best friend from high school yesterday. He told me that one of his sons (aged 6) is going blind and the doctors don't know how to stop it. He won't be able to see at all within a few years. I told him to send me the data on his son and that I would do my best to either build his son an eye, teach his son's body to rebuild it's own new eye, or find someone who can within the next 10 years. If I can't do it, maybe some of you guys can. To be honest, we are already extremely close and there are currently some options available. Much work still needs to be done, but these sorts of things ARE solvable. The smarter we are and the more smart people we have...the faster we can get there. I think the time has come to stop thinking about other humans as enemies. Call me Polyanna, but we're in this short life together and most of us actually care about other people (there's a percentage that don't). I just want to team up with the people that care and do some cool shit. That's all. =)


Ah, I thought you were referring the the mirror neurons per se as the "shared problems...", and not a part of the way to solve these problems. Reading error on my part!

That is truly commendable of you! So is this thread and all the information in it. I am also in full agreement with your vision. I am a student so I have access to a lot of databases (pubmed etc), so if anyone wants to "borrow" a full length study or w/e you can just hit me up (I can do this from my home too).

Edited by Keynes, 25 September 2013 - 09:41 PM.


#974 lostfalco

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Posted 25 September 2013 - 09:44 PM

Ah, I thought you were referring the the mirror neurons per se as the "shared problems...", and not a part of the way to solve these problems. Reading error on my part!

That is truly commendable of you! So is this thread and all the information in it. I am also in full agreement with your vision. I myself just started med school, so my knowledge is rather lackluster right now, but hopefully this will improve in the future. ;)

Because of med school I have access to a lot of databases (pubmed etc), so if anyone wants to "borrow" a full length study or w/e you can just hit me up (I can do this from my home).

haha I figured. It was a very awkwardly worded sentence. Down with mirror neurons, the scourge of humanity! ha

Very cool that you're of the same mind. I commend you as well. Hopefully, we can do some cool things.
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#975 mettmett

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Posted 25 September 2013 - 10:43 PM

Wow that mirror neurons was a good read. I'm convinced I have an excess of those. I am really good at imitating people and picking up on their mannerisms without consciously trying to. My friends get a good kick out of it when I imitate dancers on the tv on those popular shows. Really interesting..that explains how I can read people and associate with them easily. Hmm
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#976 Strangelove

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Posted 26 September 2013 - 09:18 AM

I'm gonna do this unless someone with more knowledge gives me a good reason not to. =)
http://drmyhill.co.u...unction_Profile


Very interesting, I am going to do it myself, I suspect there is an issue overtaxing my mitochondria with some health issues I have.

As I wrote in another thread.

I have come to believe that some part of decreased mental acuity from advanced age, is due to spinal degenaration if there is nerve compression. Its unbelievable the degree of mental issues I have due to (not so serious) spinal issues. Many years after a blow on the upper spine, constant (low level) pain due to nerve compression, started to have issues with brainfog, low level anxiety, and some issues with concentration. I do not believe these happen directly from anxiety, but the constant pressure on my bodily nervous system, seem to bring my brain out of balance. With much effort with exercises (yoga, pilates) some equipment for the spine (links below) I have seen improvement.


Although I have seen improvement, I still have issues with fatique, my energy is getting lower and lower over the years and I have symptoms of mild fibromyalgia started progressively after the injury. I am pretty sure the fatique is from my issues in spine as after some specific exercises in pilates and yoga as well some streching equipment, have made me feel better the last months. I am going to take a short brake, continue with pilates and start swimming and when I feel fatique and brainfog is better I ll start with TULIP again.

#977 DamnedOwl

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Posted 26 September 2013 - 09:31 AM

I'm gonna do this unless someone with more knowledge gives me a good reason not to. =)
http://drmyhill.co.u...unction_Profile


Very interesting, I am going to do it myself, I suspect there is an issue overtaxing my mitochondria with some health issues I have.


Are you guys going to stop the LLLT and supplements before taking the test? Dr.Myhill makes this remark on her website in that regard:

Avoiding nutritional supplements before the test

I am often asked whether any nutritional supplements should be discontinued prior to the tests. There is no need to stop the supplements you are taking; however, it is important to list the current supplements in the questionnaire so that I am aware of your nutritional regime. Where you are on your current supplement regime is the baseline. After all, if the supplement regime was giving you the level of wellbeing that you were satisfied with, you would not be paying for more tests. Thinking logically, what you are taking is not sufficient and the tests will identify the weak spots in that regime.


Though what she writes there is kind of re-assuring, I still can't help thinking that the results would be much easier and therefore accurate for her to interpret if all supplements and LLLT etc. stopped. I mean, would she even know how to factor in the effects of LLLT?

I suppose best of all would be to have the test done twice; initially after having stopped all regimens, and then a later one after picking all the regimens back up again. Starts getting pricey though!

#978 88LS

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Posted 26 September 2013 - 01:59 PM

Anyone thought of substituting Idebenone for CoQ10?


I take both: http://www.idebenone...-research-9.htm

LF do you know if your friend's son has Leber's hereditary optic neuropathy? If he has, then idebenone might be useful, check the LHON studies here.

Has anyone tried MitoQ? In this study its ranked among the most promising agents for treatment of mitochondrial dysfunction, these include creatine, CoQ10, idebenone and MitoQ.

Edited by 88LS, 26 September 2013 - 02:02 PM.


#979 AscendantMind

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Posted 26 September 2013 - 02:06 PM

I'm gonna do this unless someone with more knowledge gives me a good reason not to. =)
http://drmyhill.co.u...unction_Profile


Considering that Dr. Myhill mentions that ATP production is highly dependent on magnesium status, I have a suspicion that magnesium could be an important supplement to add to TULIP. More mitochondrial activity might increase the need for this mineral. It would appear also that NAD and acetyl l-carnitine would be beneficial too, though I already get enough of these.

Since I don't get enough magnesium anyways, I'm going to add magnesium threonate, a form which has been shown to be particularly capable of crossing the blood-brain barrier.

#980 Nattzor

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Posted 26 September 2013 - 03:44 PM


I think too many people measure things subjectively, which may be completely wrong.


Agreed. I want to know for sure if what I am doing works.

I'm not going to do it blinded, since some of the effects could be cumulative and long-lasting (plus the LEDs are very warm--not something I could hide effectively), but I am conducting some assessments before and a month after. Currently going to take the Cambridge Brain Challenge 5 days in a row, then TULIP for a month, then 5 more instances of the test.

I'm relatively new to cognitive self-testing; does that seem like it would be effective or am I totally off-base?


I'm blinding by holding a bag of water between my head and the LED, that seem to work.

But that looks ok.

#981 lostfalco

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Posted 26 September 2013 - 05:56 PM

I'm gonna do this unless someone with more knowledge gives me a good reason not to. =)
http://drmyhill.co.u...unction_Profile


Considering that Dr. Myhill mentions that ATP production is highly dependent on magnesium status, I have a suspicion that magnesium could be an important supplement to add to TULIP. More mitochondrial activity might increase the need for this mineral. It would appear also that NAD and acetyl l-carnitine would be beneficial too, though I already get enough of these.

Since I don't get enough magnesium anyways, I'm going to add magnesium threonate, a form which has been shown to be particularly capable of crossing the blood-brain barrier.

I believe your suspicion is probably correct. =)

I'm still working though my thoughts here so maybe we can discuss this. Tell me about your choice to go with magnesium threonate...what made you go with this as opposed to something like transdermal magnesium? A combo of oral and transdermal? Some other form? I'm genuinely asking so please don't take those as veiled arguments or something. =) Everyone else feel free to reply as well.

http://en.wikipedia....Glycolysis2.svg

Edited by lostfalco, 26 September 2013 - 06:00 PM.


#982 lostfalco

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Posted 26 September 2013 - 06:31 PM

I posted this over in Abelard's CILTEP thread as well and I thought I would share. Kinda cool, imo. http://www.longecity...920#entry614085

"Hey guys, I was just messaging with Jesse Lawler over at the Smart Drugs Smarts podcast http://smartdrugsmarts.com/ and he told me that none other than Abelard Lindsay himself is going to be the featured guest in the next week or two (either episode #21 or #22). Very cool. Props to you Abelard for CILTEP and I can't wait to hear your interview!

-Posted with Jesse's permission."

Edited by lostfalco, 26 September 2013 - 06:32 PM.


#983 AscendantMind

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Posted 26 September 2013 - 07:46 PM

I'm still working though my thoughts here so maybe we can discuss this. Tell me about your choice to go with magnesium threonate...what made you go with this as opposed to something like transdermal magnesium? A combo of oral and transdermal? Some other form? I'm genuinely asking so please don't take those as veiled arguments or something. =) Everyone else feel free to reply as well.

http://en.wikipedia....Glycolysis2.svg


I'm using magnesium threonate because it's been shown to be more bioavailable to the brain--that is, it effectively goes through the BBB. This results, at least in rats, in significant improvements in learning ability and memory:

http://www.sciencedi...896627309010447

http://www.sciencedi...896627310000346

http://www.jneurosci.../42/14871.short

I'll be taking 144 mg of this from Jarrow: http://www.amazon.co...ef=pd_sim_hpc_4

And then I will supplement with 200 mg additional magnesium in the form of magnesium citrate combined with taurine, which aids osmoregulation in terms of maintaining proper ion levels in cells. This will take me up to 85% of the RDA, which combined with my diet should provide more than enough.

However, if you have information on magnesium varieties that are even more bioavailable and/or potent, I would by all means be willing to check them out. My understanding of transdermal mag was that it was most useful for people whose stomachs couldn't handle the oral variety, and/or needed magnesium replacement therapy. I must admit that I do enjoy a relaxing Epsom salt bath from time to time, though.

Edited by AscendantMind, 26 September 2013 - 08:01 PM.


#984 Keynes

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Posted 26 September 2013 - 07:52 PM

Apparently the Swedish Customs feel like I shouldn't start with tulip, my supps from iHerb were stopped and sent back... Ridiculous. I did however order the 48-Led nattzor uses from HK, so I can probably start with that.

#985 lostfalco

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Posted 26 September 2013 - 08:06 PM

I'm using magnesium threonate because it's been shown to be more bioavailable to the brain--that is, it effectively goes through the BBB. This results, at least in rats, in significant improvements in learning ability and memory:

http://www.sciencedi...896627309010447

http://www.sciencedi...896627310000346

http://www.jneurosci.../42/14871.short

I'll be taking 144 mg of this from Jarrow: http://www.amazon.co...ef=pd_sim_hpc_4

And then I will supplement with 200 mg additional magnesium in the form of magnesium citrate combined with taurine, which aids osmoregulation in terms of maintaining proper ion levels in cells. This will take me up to 85% of the RDA, which combined with my diet should provide more than enough.

However, if you have information on magnesium varieties that are even more bioavailable and/or potent, I would by all means be willing to check them out. My understanding of transdermal mag was that it was most useful for people whose stomachs couldn't handle the oral variety, and/or needed magnesium replacement therapy.

Thanks for the info Ascendant! I'll check it out and get back to you. Let me know how it combines with TULIP. I think you're exactly right...it's so ubiquitous that it seems like something 100% worth making sure we optimize.

Apparently the Swedish Customs feel like I shouldn't start with tulip, my supps from iHerb were stopped and sent back... Ridiculous. I did however order the 48-Led nattzor uses from HK, so I can probably start with that.

Wow. They sent back supplements? Holy crap that's strict.

#986 8bitmore

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Posted 26 September 2013 - 09:06 PM

Wow. They sent back supplements? Holy crap that's strict.


That's Sweden for you. Honestly. If you want booze then its down to the government owned 'Systembolaget'.

#987 Keynes

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Posted 26 September 2013 - 09:28 PM

Wow. They sent back supplements? Holy crap that's strict.


That's Sweden for you. Honestly. If you want booze then its down to the government owned 'Systembolaget'.


Wouldn't surprise me if they sent me the bill for the "clearance" either (standard procedure). None of the supps are restricted here, (I had some theanine, 5-mthf, lion's mane etc apart from the pqq/coq10). You can buy it all domestically if you want to pay 200%. But I can see the customs officer scratching his head after seeing a bunch of pills with strange names from an internet shop called "iHerb" (omg it's drugs)...

#988 Ukko

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Posted 27 September 2013 - 01:08 AM

Wow. They sent back supplements? Holy crap that's strict.


That's Sweden for you. Honestly. If you want booze then its down to the government owned 'Systembolaget'.


Wouldn't surprise me if they sent me the bill for the "clearance" either (standard procedure). None of the supps are restricted here, (I had some theanine, 5-mthf, lion's mane etc apart from the pqq/coq10). You can buy it all domestically if you want to pay 200%. But I can see the customs officer scratching his head after seeing a bunch of pills with strange names from an internet shop called "iHerb" (omg it's drugs)...


Yeah, I think the Nordic countries are really retarded and suspicious on things like that. I bet you anything some lazy fat f*** at the Swedish customs saw that you ordered mushrooms....MUSHROOMS....svampar, vad fan? You must be planning to get high somehow. The retards at customs are like 30-50 years away from realizing that someone somewhere might eat mushrooms for health benefits.

#989 dreth7

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Posted 27 September 2013 - 02:30 AM

For those that have read The Machinery of Life or Life's Ratchet, how in depth are they. I'm currently in medical biochemistry and have taken multiple semester of cellular biology/ genetics. I was curious if they would augment my studies or be redundant.

I haven't kept up with this thread for a long time (studies took over). Looks like there is some seriously worthwhile information in here. Anecdotally people seem to be achieving great success from the light therapy. I'll sift through the pages and probably join in on the great journey :) I could definitely benefit with my crazy workload in medical school.

I did notice someone posted about increased testosterone production of the testes from LLLT. Was that achieved through the same LEDs you advocate using? I guess i'll have to start my own research. :D

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#990 Godof Smallthings

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Posted 27 September 2013 - 03:31 AM

Wow. They sent back supplements? Holy crap that's strict.


That's Sweden for you. Honestly. If you want booze then its down to the government owned 'Systembolaget'.


Wouldn't surprise me if they sent me the bill for the "clearance" either (standard procedure). None of the supps are restricted here, (I had some theanine, 5-mthf, lion's mane etc apart from the pqq/coq10). You can buy it all domestically if you want to pay 200%. But I can see the customs officer scratching his head after seeing a bunch of pills with strange names from an internet shop called "iHerb" (omg it's drugs)...


Here are the rules applied by customs:

http://www.lakemedel...classification/





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