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Here it is, IDRA-21

glutamate idra-21 nmda health memory ltp

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379 replies to this topic

#181 Izan

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Posted 30 June 2013 - 09:35 PM

yadayada, please count me in for a pitolisant group buy. thank you.

#182 trev.pol

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Posted 01 July 2013 - 12:31 AM

im also in for pitolisant

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#183 meta1

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Posted 01 July 2013 - 01:57 AM

Please count me in for pitolisant.

#184 PWAIN

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Posted 01 July 2013 - 09:26 AM

Getting in early...in for pitolisant group buy it/when it happens

#185 Colli

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Posted 01 July 2013 - 10:49 AM

I'm in for a pitolisant group buy too. I should have the funds available by the time it becomes a reality.

#186 spookytooth

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Posted 01 July 2013 - 11:00 AM

I'm interested in the pitolisant group buy!

#187 Hebbeh

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Posted 01 July 2013 - 11:55 AM

Are we taking names for pitolisant in the IDRA-21 thread now?
  • Pointless, Timewasting x 1

#188 Izan

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Posted 01 July 2013 - 01:42 PM

Are we taking names for pitolisant in the IDRA-21 thread now?

that's how it also started with the isrib groupbuy in the pkr c16 thread. i didn't even had a chance, lol.

#189 uralsky

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Posted 01 July 2013 - 02:24 PM

In for Pitolisant too

#190 phil8462643

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Posted 01 July 2013 - 03:20 PM

I am in too! of course i am in!

#191 Perception-Is-Reality

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Posted 01 July 2013 - 07:47 PM

im in, if it costs $150 or less.

#192 ScienceGuy

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Posted 04 July 2013 - 03:59 AM

IDRA-21 USER FEEDBACK:

DAY ONE: I took 5mg SUBLINGUALLY upon waking. No adverse effects whatsoever. No significant noticeable beneficial effects, aside from a mild increase in alertness; although this was most welcome given I had a 4am start :)

DAY TWO: I took 5mg SUBLINGUALLY upon waking again. Given that IDRA-21 is reported to exert a 3-DAY EFFECT I did this deliberately, expecting this second dose to be cumulative. In short, it was. I experienced a stronger increase in alertness, but this time I also experienced a sharpening of focus and cognition; however, it seemed to be accompanied by a jittery restlessness and manifestation of mild anxiety, which is akin to what happens when I consume too much caffeine. This is not entirely pleasant and is a bit of a bummer because it essentially spoils the alertness increase. :unsure:

I am going to take a break long enough to complete a washout period and then re-try IDRA-21 to ascertain whether both positive and negative effects are repeated. Of course, even if I personally find that I do not get along with IDRA-21 that does not mean you won't. It is probably worth mentioning that I do not respond well to ANIRACETAM either, which produces similar adverse effects when I take it, including increased anxiety. ;)


IDRA-21 USER FEEDBACK - UPDATE:

After taking a sufficiently long washout period I measured out and labelled 2 number 10MG doses of IDRA-21. I then measured out and labelled 2 number 10MG doses of MALTODEXTRIN. I gave the respective labelled individual doses to a colleague with instructions to provide me with either the IDRA-21 or MALTODEXTRIN doses with the same compound on 2 consecutive days, and with a 7 day washout period in-between the two, but without my knowing which way around (i.e. whether IDRA-21 first or second). I did this to eliminate possible influence of NOCEBO and PLACEBO effects by taking them BLIND. ;)

In short, with regards to the MALTODEXTRIN (which was provided to me first) I did not experience any noticeable effects.

But, I experienced precisely the same negative adverse effects from the IDRA-21 (which was provided to me second) as per before, with increased intensity (likely due to the higher dosage) and also with a couple of others which included: Headache; Thirst; Nausea; Depression; and a WORSENING of Cognitiive Function, specifically Brain Fog, Difficulty Concentrating, Impaired Memory. I did experience a positive increase in alertness shortly after dosing, however this seemed short-lived and was quickly overcome by the adverse effects and feeling brain-fogged and spaced out. :|?

Consequently, I have concluded that I really do not like the effects of IDRA-21 :|o

Please kindly note that this is simply a singular user feedback report and does not mean than everyone will respond to IDRA-21 the same way. ;)
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#193 3AlarmLampscooter

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Posted 04 July 2013 - 05:02 AM

But, I experienced precisely the same negative adverse effects from the IDRA-21 (which was provided to me second) as per before, with increased intensity (likely due to the higher dosage) and also with a couple of others which included: Headache; Thirst; Nausea; Depression; and a WORSENING of Cognitiive Function, specifically Brain Fog, Difficulty Concentrating, Impaired Memory. I did experience a positive increase in alertness shortly after dosing, however this seemed short-lived and was quickly overcome by the adverse effects and feeling brain-fogged and spaced out. :|?

Consequently, I have concluded that I really do not like the effects of IDRA-21 :|o


Sounds like you've found an excellent replacement for Klonopin's niche role as a performance decreasing drug. :laugh:
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#194 violetechos

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Posted 26 July 2013 - 01:55 AM

Please, count me in.

#195 Reformed-Redan

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Posted 26 July 2013 - 02:30 AM

Please, count me in.

Sorry, I dropped this group buy after I heard from ScienceGuy's feedback. Not sure its worth it. Still interested in pitolisant though. Wonder when will Googletarian get back to us.

#196 violetechos

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Posted 26 July 2013 - 03:30 AM

IDRA-21 seems like a mercurial crowbar when most users need a plasma torch right now, you understand?

I am interested in a supply still but I can wait.

Edited by violetechos, 26 July 2013 - 03:45 AM.


#197 unregistered_user

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Posted 12 October 2013 - 12:32 AM

New Star Nootropics will begin carrying this in a week or two.

#198 Reformed-Redan

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Posted 12 October 2013 - 12:48 AM

Derp.

#199 Nattzor

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Posted 12 October 2013 - 10:46 AM

New Star Nootropics will begin carrying this in a week or two.


Do not trust their time schedule, they were REALLY late with Coluracetam, they said to me that PRL-8-53 could come as early as September 1st (kinda implying it would atleast happen around there), still nothing, etc.

#200 Bismarck

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Posted 28 October 2013 - 03:04 AM

I have 1KG idra - 21. I will sell 10g @ 200 usd including international registred shipping ( fedex/dhl ) . Pls pm if anyone is interested.

#201 Reformed-Redan

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Posted 28 October 2013 - 03:30 AM

I have 1KG idra - 21. I will sell 10g @ 200 usd including international registred shipping ( fedex/dhl ) . Pls pm if anyone is interested.

Lol, this is some scary shit.
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#202 Bismarck

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Posted 28 October 2013 - 03:34 AM

How is it scary?

#203 Reformed-Redan

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Posted 28 October 2013 - 03:57 AM

Could you send a sample for testing purposes? Say that 10g, and 1g from that amount will be tested to see purity and quality of product. If it contains any toxic intermediaries.

#204 Bismarck

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Posted 28 October 2013 - 04:04 AM

!0g is a bit much for a sample. Id be willing to sell a few samples at cost . Shipping alone is 50 - 70$. That said I can tell you I buy from the same supplier as newstar. I can supply factory certificates.

#205 p3x888

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Posted 30 October 2013 - 10:28 PM

Newstar has theirs now.

#206 ihsanozkan

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Posted 30 October 2013 - 10:31 PM

And I ordered it :)

#207 Perception-Is-Reality

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Posted 30 October 2013 - 10:41 PM

Is the active normal dosage really only .1mg?

#208 p3x888

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Posted 31 October 2013 - 12:03 AM

Is the active normal dosage really only .1mg?


I thought Scienceguy calculated it this way -
http://www.longecity...post__p__594797

"I should add that I have calculated the HUMAN EQUIVALENT DOSAGE (HED) range for IDRA-21 using the study on MONKEYS as the reference; wherein, the 'best dose' range for the MONKEYS was reported to be 0.15 - 3 MG / KG

Therefore, the HED = 0.15 x (12 / 37) to 3 x ( 12 / 37) = 0.049 to 0.973 MG / KG ;)

I currently weigh 92kg and hence my HED would be = 4.5 to 89.5mg

Hence why I took 5mg as my first dose :)"

Hope this helps.
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#209 Perception-Is-Reality

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Posted 31 October 2013 - 01:43 AM

It does, I would love to hear what perceived effects you (or others) experience from dosing.

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#210 Amorphous

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Posted 31 October 2013 - 02:36 AM

Just ordered a small quantity from NSN to try out. Hopefully I'll have a different experience than ScienceGuy and Idra-21 works well with me - just like aniracetam agree with me well and not him.
It is scary since its effect may last for 3 days from a single dose. I think I will wait for a long holiday or vacation before actually trying this thing out.





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