jdtic kappa antagonist bulk/group buy
#541
Posted 14 February 2014 - 10:13 AM
#542
Posted 14 February 2014 - 10:31 AM
socialpiranha im not sure how much is damage and how much is just extra dissociation...dissociation is causing all my cognitive problems and more detachment from my body etc
i have had an MRI brain scan a couple of months ago and that came back all good....but if we talking messed up chemistry then Im not sure about that coz mine cud very well be messed up
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#543
Posted 14 February 2014 - 02:30 PM
as for the group buy, i can add some more money if need be
Edited by addx, 14 February 2014 - 02:53 PM.
#544
Posted 15 February 2014 - 12:26 AM
come on people, let's get this going. for those of you on the fence, jump down and make the sacrifice, even if it hurts. this has potential to induce a de facto remission of your affliction or at least enable all your other coping therapies work that much more effectively. it's worth eating ramen for a month.
#545
Posted 15 February 2014 - 01:00 AM
#546
Posted 15 February 2014 - 01:01 AM
#547
Posted 15 February 2014 - 03:19 AM
#548
Posted 15 February 2014 - 03:52 AM
#549
Posted 15 February 2014 - 04:22 AM
#550
Posted 15 February 2014 - 09:31 PM
#551
Posted 16 February 2014 - 12:56 AM
Edited by socialpiranha, 16 February 2014 - 01:05 AM.
#552
Posted 17 February 2014 - 03:30 PM
http://www.qiagen.co...s.aspx?pwid=140
any drugs that can "touch" that?
#553
Posted 17 February 2014 - 06:22 PM
#554
Posted 17 February 2014 - 06:57 PM
wtf is this, first time I ran into it
http://www.qiagen.co...s.aspx?pwid=140
any drugs that can "touch" that?
I think if you're thinking about getting rid of pain, then this looks promising ?
http://www.axonmedch...816a784168.html
#555
Posted 17 February 2014 - 07:27 PM
I'm starting to think that the effects may gradually increase through a day or two after taking it. So, I may have taken too much when I took a second dose on the same day and may be the reason for the negative effects.
I just felt a slight discomfort in my body which I can't really pinpoint the area. I also felt a little spaced out. Two days after my first dose and I still felt a 'glow' effect that's kind of hard to describe. Maybe I was starting to feel the good effects again from the first day now that the dose that was too large partially wore off.
Now, I'm taking a break off JDTic to see the residual effects and I think I'm doing fine. It seems like to glow feeling has mostly worn off, but there might be a slight increase in clarity of thought. There might have also been an increase in dopamine, but I can't be certain.
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#556
Posted 18 February 2014 - 01:43 AM
#557
Posted 18 February 2014 - 04:20 AM
#558
Posted 18 February 2014 - 04:35 AM
You are incorrect yet another time. The particular datasheet I posted is not on the website.that's just an unlabeled vial and the data sheets which can be found on medchems site.
#559
Posted 18 February 2014 - 04:41 AM
#560
Posted 18 February 2014 - 11:38 AM
I thought u said to me that u sold it to a other person.(jdtic)Even if I showed the label and not show the powder, you'll just say I printed the label and attached it to the vial. You're ridiculous.
Edited by alex921, 18 February 2014 - 11:39 AM.
#561
Posted 18 February 2014 - 12:13 PM
Because of the heart stuff, someone expressed caution about a TCA, and I'm guessing that reserve might naturally extend to MAOIs too ..
But things like SSRIs, mood-stabilizers ..? Stimulants?
I've seen moderate doses of Suboxone prescribed in psychotropic cocktails, so presume kappa antagonism in and of itself can't pose a serious interaction risk? Unless the opiate agonism mitigates some of that ..
#562
Posted 18 February 2014 - 08:53 PM
http://www.molport.c...chemicals/index
Sorry I do not have time to search it, just a quick info on it. Years ago I was trying to source a hard to find chemical, I had the same issue with all the sources I tried as social piranha mentions (nessecery paperwork...). I found moleport, they used to be an intermediary (I do not know if anything changed by now) for larger companies, getting a fee for their services in acquiring and reselling the chemical needed. I did not buy anything from them, but I remember they used to be really easy on the "credentials" needed.
I do not remember all the details of what they wanted, but I clearly remember that they were very helpful in completing your purchase... Sorry again that I am not more helpful, but check it out, maybe it worths it.
#564
Posted 19 February 2014 - 06:44 AM
Can someone look into having it analyzed by a third party i am low on time and my efforts to find a place haven't panned out yet.
Sorry my private groups still haven't been approved by the mods , i think the staff is pretty limited here unfortunately.
#565
Posted 19 February 2014 - 12:28 PM
I'm feeling somewhat different since then, it's like it reduced my neuroticism 10 fold. No emotional overreactions causing compulsive/limited/neurotic thinking in giving a reply to someone etc. Most obvious change was ability to look people in the eyes. It was just so natural, I just noticed that I'm actually looking at people with no fear as if they'll see into my soul. Shrooms made me somehow more "plain" - grounded. They seem to reduce repeating thoughts, negative repeating thoughts or whatever, negative thought loops. Reduce might not even be the right word. It like right when the negative thinking is about to occure it gets overriden by a "transient serotonergic defocusing feeling" which completely preempts the frustration that is about to happen
It does seem to be wearing off, now 3rd day already... seems like a similar timespan to ketamine/salvia "antidepressant effects".
#566
Posted 19 February 2014 - 02:36 PM
Does anyone has any idea what would be a good start?
I mean I don't even know if we should be in the 10 microgram or the 1 milligram kind of range.
I really wonder what doses give what percentages of KOR antagonism in the brain. Could there be a rat study result of this? Cause I fear they are useless since they always give huge amounts to the poor animals (like 10mg/kg body weigt for JDTic), which can not be easily compared to a human dose (also because they have a different rate of metabolism). Maybe we should just depend on the only human trial and assume 1mg is a good amount, but what if a tenth would give the same effect? would be a huge waste of money to take 1mg in that case....
Edited by Remon, 19 February 2014 - 02:41 PM.
#567
Posted 19 February 2014 - 11:17 PM
I have ended up buying some savlia tincture and some savlia tea leaves. I will try sublingually administration daily, and post results in this thread. I'm not aiming for a dose which will make me lose touch with reality, hopefully I can get a good dose sublingually without the major dissosiative effects.
#568
Posted 20 February 2014 - 12:20 AM
I have ended up buying some savlia tincture and some savlia tea leaves. I will try sublingually administration daily, and post results in this thread. I'm not aiming for a dose which will make me lose touch with reality, hopefully I can get a good dose sublingually without the major dissosiative effects.
The degree of kappa downregulation should be proportional to the disassociation caused. That said, I hope chronic dosing works too.
#569
Posted 20 February 2014 - 08:22 AM
Not really sure this belongs in here but I can't see any other active threads so I'll post it here.
I have ended up buying some savlia tincture and some savlia tea leaves. I will try sublingually administration daily, and post results in this thread. I'm not aiming for a dose which will make me lose touch with reality, hopefully I can get a good dose sublingually without the major dissosiative effects.
It depends on how resistant the individual is. I can smoke 5X Salvia without tripping, although I do get slight psychosis for about 30 seconds after inhaling a whole cigarette filled with 5X.
I tried 10X but that will cause you to "break through" into another world. Stick with 5X or the leaves.
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#570
Posted 20 February 2014 - 08:42 AM
Kappa Agonism seems to be very effective at stopping mania.
Another indication that JDTic will probably be very beneficial for unipolar depression.
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