Ginsenoside Rp1 from Panax Ginseng inhibits the IGF-1R/Akt pathway in human breast cancer cells according to this study: http://www.ncbi.nlm....pubmed/21748437
IGF-1 is important for growth and height. Inhibiting it when the growth plates have not yet fused can possibly have a detrimental effect on final adult height. Does Rp1 affect circulating IGF-1 and therefore height? Also, does American Ginseng contain Rp1?