34 replies to this topic

[Kryzpo]

+1

[Junk Master]

Man, I had to take MASSIVE doses of inositol to feel any effects.  Over 20 G for sure.  It was useful but unsustainable at those quantities because it caused intestinal distress (no kidding, huh).

 

I've tried every one of the supps mentioned here, like Valerian root, and have not found any to have true "drug-like" effects.

 

I am not recommending this because it's a controversial chemical here, but a gram of phenibut will crush all social anxiety without sedating effects.  1/2 Mg of Clonazepam will do it too, with mildly sedating effects.  1/2 Mg of Clonazepam and 100 mg of Modafinil is the martini of social lubricants.  Compare that with 10 g inositol and a red bull.

 

Valerian root v. low dose zolpidem.  Valerian v. baclofen.  Valerian v. etizolam.  I could keep going...point is, if Valerian root does it for you, great!  But I know I could triple/quadruple a typically recommended dose of Valerian root and not feel a thing besides most likely sick to my stomach from all the pills, and I don't believe I'm THAT unusual.

Edited by Junk Master, 10 June 2016 - 01:25 PM.

[birthdaysuit]

The highest dose I took was 40g of myo-inositol and it put me in a stupor, I couldn't even speak the English language without slurring my speech. 10g was much better but in the long-term it made me extremely agitated and callous. I was emotionally unbalanced and spacey. It’s bizarre because super loading inositol is required for any neurological effects. When I use it to super load sporadically, I did not experience any of the negative side effects, maybe it’s cumulative?

 

Myo-inositol has therapeutic effects in the spectrum of illness responsive to serotonin selective re-uptake inhibitors, including depression, panic and OCD and long term use can even up-regulate D2 receptors.

 

http://www.ncbi.nlm....pubmed/11267629

 

Adults with Down syndrome have a significantly increased brain concentration of myo-inositol, and this is associated with reduced cognitive ability. Future studies are required to relate myo-inositol concentration in people with DS to brain development and increased risk for developing Alzheimer disease.

 

http://www.ncbi.nlm....pubmed/16330724

 

Inositol can cause too much intracellular calcium which can be responsible for myoclonic jerks and muscle twitches. Magnesium, potassium and zinc supplementation can modulate these side effects.

 

Inositol also inhibits iron and zinc transport

 

http://www.ncbi.nlm..../pubmed/8145081

 

myo-Inositol (1,2,3,4,5,6)hexakisphosphate (phytate), the major storage form of phosphorus in plants, has been considered to be an anti-nutrient due to its inhibitory effect on bioavailability of essential dietary minerals (Cheryan, 1980).
 
http://www.sciencedi...16816560000331X

 

Increased myo-inositol may represent tardive glial scarring in the prefrontal cortex, a notion supported by GFAP changes in this region after blast overexposure as well as clinical reports of increased myo-inositol in disorders of memory.
 
http://www.ncbi.nlm....pubmed/24534010

 

Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial.
 
Treatment of PCOS patients with Myo-inositol provided a decreasing of circulating insulin and serum total testosterone as well as an improvement in metabolic factors. Reduce serum Total testosterone by as much as 40% in women.

 

http://www.ncbi.nlm....pubmed/19499845

 

 

 

 

 

 

 

 

 

 

 

[birthdaysuit]

Man, I had to take MASSIVE doses of inositol to feel any effects.  Over 20 G for sure.  It was useful but unsustainable at those quantities because it caused intestinal distress (no kidding, huh).

 

I've tried every one of the supps mentioned here, like Valerian root, and have not found any to have true "drug-like" effects.

 

I am not recommending this because it's a controversial chemical here, but a gram of phenibut will crush all social anxiety without sedating effects.  1/2 Mg of Clonazepam will do it too, with mildly sedating effects.  1/2 Mg of Clonazepam and 100 mg of Modafinil is the martini of social lubricants.  Compare that with 10 g inositol and a red bull.

 

Valerian root v. low dose zolpidem.  Valerian v. baclofen.  Valerian v. etizolam.  I could keep going...point is, if Valerian root does it for you, great!  But I know I could triple/quadruple a typically recommended dose of Valerian root and not feel a thing besides most likely sick to my stomach from all the pills, and I don't believe I'm THAT unusual.

 

I think many people who suffer from social anxiety have a hormonal imbalance or mineral deficiencies. For me I had severely low testosterone with fluctuating E2. I abstained from masturbating and with TRT injections my social anxiety became none-existent. I mean completely gone with the injections. Although I don't recommend TRT injections to everyone with low T.
 

[normalizing]

so overall inositol is not good option for people with 5ht2c receptor problems?