30 replies to this topic

[Coffeee]

I had a rare reaction to a supplement called pramiracetam. I took a supplement which caused neural death of sexual function within my brain, im essentially impotent without viagra.

Would the brain restore itself or is this just the way it is.

Its been about 3 months since i lasst took the supplement. Still no morning wood any more and when im suposed to have sex i dont get aroused.

I went to 2 doctors that were totally clueless

[Absent]

That's strange. How much Pramiracetam did you take? You called it a rare reaction, so do you know anything more specific? Why do you specifically say it "caused neural death of sexual function". That is a extremely broad overstatement. Sexual function is linked to a vast number of things. Acetylcholine, Testosterone, Dopamine, etc. Even all major neurotransmitters. Anything to do with Motivation Mood, ie, Serotonin, Oxytocin, the aforementioned ones. Sexual excitement can also come from Norepinephrine, epinephrine, adrenalin, etc.

I personally don't believe any brain alteration from any supplement or drug is permanent forever. The brains sole function is to change.

You're going to have to be way more specific. Nothing turns you on? Porn? Girls? Making out? Touching? Do you have an idea of what usually turns you on?

To be honest, I wish I could overcome my sexual urges and eliminate them all together, because I feel like they are just a waste of my energy that I could be using elsewhere. With this said, do you also feel your motivation to life activities down? Depression? Lethargy? Etc? Details, need them!

Edited by Siro, 30 November 2013 - 06:17 AM.

[Coffeee]

That's strange. How much Pramiracetam did you take? You called it a rare reaction, so do you know anything more specific? Why do you specifically say it "caused neural death of sexual function". That is a extremely broad overstatement. Sexual function is linked to a vast number of things. Acetylcholine, Testosterone, Dopamine, etc. Even all major neurotransmitters. Anything to do with Motivation Mood, ie, Serotonin, Oxytocin, the aforementioned ones. Sexual excitement can also come from Norepinephrine, epinephrine, adrenalin, etc.

I personally don't believe any brain alteration from any supplement or drug is permanent forever. The brains sole function is to change.

You're going to have to be way more specific. Nothing turns you on? Porn? Girls? Making out? Touching? Do you have an idea of what usually turns you on?

To be honest, I wish I could overcome my sexual urges and eliminate them all together, because I feel like they are just a waste of my energy that I could be using elsewhere. With this said, do you also feel your motivation to life activities down? Depression? Lethargy? Etc? Details, need them!

in the morning my duck is like 10 percent hard. I used to masutbate like every 2 days, wake up with a flag pole, always horny, after the dose of pramiracetam that all changed, its been 3 months and no morning wood still.

doctors said alll my levels were fine, so it has to be neural damage to my brain.

[Absent]

Why do you interpret that as damage, though?

I bet you most people would not go masturbate or think of doing it unless they were horny in the first place. A mind that is focused and working hard on something is not easily distracted and thus not going to easily ruminate to sexual thoughts. This has been my experience.

In the past I used to masturbate a lot, but decided to stop. I got urges a lot but overtime the urges were less and less. The wet dreams became less and less, and eventually I stopped getting morning wood all together. My mind doesn't ruminate as much to sexual thoughts and I don't masturbate anymore... there are times when I am not feeling very focused, maybe due to lack of sleep, and that day I will get very horny.

So perhaps Pramiracetam enhanced your focusing ability o.o.

This is just my take on it. On good days where I have been hard working and my mind is highly focused, even if I try to watch porn, it just doesn't interest me, nor does meaningless sex with somebody. It really depends. To me, this is a good thing.

Do you just not get turned on anymore? You said you need Viagra, does that mean you have not been able to get turned on in normal sexual encounters? I hope you're not using Viagra to masturbate lol.

[Ark]

Please consider getting screened for Bipolar disorder, not meant as a insult , trust me I have experience in this subject it is nothing to be ashamed of.

[Absent]

I am finding it hard to believe a single dose of Pramiracetam could cause something like that, to be honest. You still never told us how much of it you took.

[Coffeee]

I am finding it hard to believe a single dose of Pramiracetam could cause something like that, to be honest. You still never told us how much of it you took.

500 mg


then 250 mg a week later to see if it would worsen my ED, and it seems it did

[Ark]

I am finding it hard to believe a single dose of Pramiracetam could cause something like that, to be honest. You still never told us how much of it you took.

500 mg


then 250 mg a week later to see if it would worsen my ED, and it seems it did

It sounds more like it is in your head.

[noktop]

IGNORE THIS THREAD. This guy is a spammer who has been posting the same thread for multiple days now. He has what appears to be serious mental problems not caused by prami.

[Guardian4981]

I'd somewhat agree with Ark, sounds like it could be some bipolar to me. People with this disorder often rotate between alot of libido and very low or none.

[Coffeee]

IGNORE THIS THREAD. This guy is a spammer who has been posting the same thread for multiple days now. He has what appears to be serious mental problems not caused by prami.

Jackass post of the day, get a life.

[BlueCloud]

doctors said alll my levels were fine, so it has to be neural damage to my brain.

yes, I'm sorry to say that it is indeed neural damage to your brain, and it's permanent I'm afraid. It will also make you completely amnesic , to the point of creating 7 different threads relating the same story and forgetting about them :
http://www.longecity...m-pramiracetam/
http://www.longecity...etam-permanent/
http://www.longecity...and-nootropics/
http://www.longecity...ain-permanetly/
http://www.longecity...egal-in-the-us/

Have you noticed any of the following symptoms : skin and hair slowly turning green, uncontrollable hysterical laughters and urges to post on various forums while dressed only in "Star Wars" branded underwear , etc.. ? This could be a confirmation that it is permanent and irreversible. Nothing can be done, I'm sorry.
I've seen however a serious double-blind study at Hobbit University that getting a job as a hostess in various Fantasy and Comic-Con conventions could slowly reverse the symptoms, but it might take up to 100.00056 years. Worth a shot in my opinion.
Hope this helps.

[Coffeee]

doctors said alll my levels were fine, so it has to be neural damage to my brain.

yes, I'm sorry to say that it is indeed neural damage to your brain, and it's permanent I'm afraid. It will also make you completely amnesic , to the point of creating 7 different threads relating the same story and forgetting about them :
http://www.longecity...m-pramiracetam/
http://www.longecity...etam-permanent/
http://www.longecity...and-nootropics/
http://www.longecity...ain-permanetly/
http://www.longecity...egal-in-the-us/

Have you noticed any of the following symptoms : skin and hair slowly turning green, uncontrollable hysterical laughters and urges to post on various forums while dressed only in "Star Wars" branded underwear , etc.. ? This could be a confirmation that it is permanent and irreversible. Nothing can be done, I'm sorry.
I've seen however a serious double-blind study at Hobbit University that getting a job as a hostess in various Fantasy and Comic-Con conventions could slowly reverse the symptoms, but it might take up to 100.00056 years. Worth a shot in my opinion.
Hope this helps.

dic head post of the day

[Ark]

doctors said alll my levels were fine, so it has to be neural damage to my brain.

yes, I'm sorry to say that it is indeed neural damage to your brain, and it's permanent I'm afraid. It will also make you completely amnesic , to the point of creating 7 different threads relating the same story and forgetting about them :
http://www.longecity...m-pramiracetam/
http://www.longecity...etam-permanent/
http://www.longecity...and-nootropics/
http://www.longecity...ain-permanetly/
http://www.longecity...egal-in-the-us/

Have you noticed any of the following symptoms : skin and hair slowly turning green, uncontrollable hysterical laughters and urges to post on various forums while dressed only in "Star Wars" branded underwear , etc.. ? This could be a confirmation that it is permanent and irreversible. Nothing can be done, I'm sorry.
I've seen however a serious double-blind study at Hobbit University that getting a job as a hostess in various Fantasy and Comic-Con conventions could slowly reverse the symptoms, but it might take up to 100.00056 years. Worth a shot in my opinion.
Hope this helps.

dic head post of the day

floppy or hard post of the day, you d3cide friend.

[Homer12]

Why does it always feel like the people posting most of the stuff here are between the ages of 17 and 22.

no one on this forum, no matter how many links they back it up with, is qualified to tell you that you have neural damage. Its absolutely ridiculous. Anyone who does probably falls between that age group as well and is beyong underqualified. You yourself are also underqualified to self-diagnose neural brain damage.

Jesus what is wrong with some of you.

[perplex]

Coffee,

Follow my advice, you have nothing to lose from it:

Acetylcholine is responsible for the signaling and arousal (getting erections). In some, their acetylcholine supply just get used up way faster. If you lay off everything else and supplement continuously with a strong choline precursor (CDP, AGPC) that crosses the blood brain barrier you should start seeing results.

on another note, do you smoke weed or take anything else like phenibut? more information would be helpful

Edited by perplex, 03 December 2013 - 01:22 PM.

[Coffeee]

Coffee,

Follow my advice, you have nothing to lose from it:

Acetylcholine is responsible for the signaling and arousal (getting erections). In some, their acetylcholine supply just get used up way faster. If you lay off everything else and supplement continuously with a strong choline precursor (CDP, AGPC) that crosses the blood brain barrier you should start seeing results.

on another note, do you smoke weed or take anything else like phenibut? more information would be helpful

i bought soy letchin took it for a week with no results so i stopped.

[noktop]

Neither Lecithin or DMAE are good sources of choline when compared to Alpha GPC or CDP Choline.

The way I see, it there are a few causes of this:

• The pramiracetam was affected by other medication you were taking at the time,
• The batch was toxic,
• You had previous mental or health issues that were exacerbated,
• Something else is causing it that you incorrectly assumed was pramiracetam
• It's all in your mind.

Have you explored any other solutions in this thread?

[BlueCloud]

Jesus what is wrong with some of you.

This is what's wrong :

fine you discovered my plan I will tell you why i did this
because i hate nootropics in general thats all, nootropics are evil. i want to destroy these markets with false allegations alright?
you found out my plan but the lies were spread everywhere, everwhere on the internet and to all the peopl i know who use these stuff.
cognitive enhancement and psychoactives are extremely evil, i am sick to see one of my "friends" always telling me that it makes his brain better, yeah i will put a fucking poison in his nootropics and we shall see if his brain stays better, prepare for a vegetable life fucker

anyway all what you do is bad and you are all bad

http://www.longecity.org/forum/topic/60653-parathion-horror-story-lasting-for-months-and-still-ongoing/page__st__60#entry559675

Same as this :
http://www.longecity...-my-balls-help/
http://www.longecity...acetam-victims/

[perplex]

Coffee,

tell us more of what other substances you were trying around that time so we are aware of other possible interaction (if you don't give any more info how are people to help?)

it might acetylcholine levels are extremely low.

If you don't want to try supplementing with acetylcholine sources you can try a acetylcholinerase such as huperizine A or galantamine:

Studies have shown it to be valuable for psychogenic impotence, or psychologically caused sexual dysfunction. One study found that 30 days of treatment with 10 mg of galantamine taken three times daily resulted in stabilizing erectile function and eliminating premature ejaculation in 108 of 170 men, a 64% success rate.¹¹

• Ludianskii EA. On the use of anticholinesterase agents in the treatment of neurological diseases.Sov Med 1964 Mar;27:84-7

Edited by perplex, 03 December 2013 - 09:22 PM.

[noktop]

Jesus what is wrong with some of you.

This is what's wrong :

fine you discovered my plan I will tell you why i did this
because i hate nootropics in general thats all, nootropics are evil. i want to destroy these markets with false allegations alright?
you found out my plan but the lies were spread everywhere, everwhere on the internet and to all the peopl i know who use these stuff.
cognitive enhancement and psychoactives are extremely evil, i am sick to see one of my "friends" always telling me that it makes his brain better, yeah i will put a fucking poison in his nootropics and we shall see if his brain stays better, prepare for a vegetable life fucker

anyway all what you do is bad and you are all bad

http://www.longecity..._60#entry559675

Same as this :
http://www.longecity...-my-balls-help/
http://www.longecity...acetam-victims/

I thought that at first, but then I looked at his threads and figured he really must have some sort of brain damage.

Edited by noktop, 04 December 2013 - 03:06 AM.

[Coffeee]

Neither Lecithin or DMAE are good sources of choline when compared to Alpha GPC or CDP Choline.

The way I see, it there are a few causes of this:

• The pramiracetam was affected by other medication you were taking at the time,
  
• The batch was toxic,
  
• You had previous mental or health issues that were exacerbated,
  
• Something else is causing it that you incorrectly assumed was pramiracetam
  
• It's all in your mind.

Have you explored any other solutions in this thread?

i bought it from http://healthsupplem...holesalers.com/, they seem legit and supposedly have 3rd party testing, so i really dont know.

As for other meds, ive been poping things left and right with really no side effects on my sexuality. Near this time of the drop in sexuality i took a megadose of L-Glycine and and Creatine monohydrate.

I took noopept like a madman with no affect on libido, phenylpiracetam had no affect on libido,

although i did take piracetam around this time, i remember a feeling of physical change within my brain just a little while after taking pramiracetam.

[Coffeee]

Coffee,

Follow my advice, you have nothing to lose from it:

Acetylcholine is responsible for the signaling and arousal (getting erections). In some, their acetylcholine supply just get used up way faster. If you lay off everything else and supplement continuously with a strong choline precursor (CDP, AGPC) that crosses the blood brain barrier you should start seeing results.

on another note, do you smoke weed or take anything else like phenibut? more information would be helpful

ill take a couple of grams of choline bitrate ill tell u what happens.

[Coffeee]

Coffee,

tell us more of what other substances you were trying around that time so we are aware of other possible interaction (if you don't give any more info how are people to help?)

it might acetylcholine levels are extremely low.

If you don't want to try supplementing with acetylcholine sources you can try a acetylcholinerase such as huperizine A or galantamine:

Studies have shown it to be valuable for psychogenic impotence, or psychologically caused sexual dysfunction. One study found that 30 days of treatment with 10 mg of galantamine taken three times daily resulted in stabilizing erectile function and eliminating premature ejaculation in 108 of 170 men, a 64% success rate.¹¹

• Ludianskii EA. On the use of anticholinesterase agents in the treatment of neurological diseases.Sov Med 1964 Mar;27:84-7

I am going to the vitamin shop and will buy galantamine and give it a try, thanks friend.

[platypus]

So nefiracetam shrunk your balls too, right?

[perplex]

You see here is the important part:

Choline bitrate or lecithin won't really yield results for this matter. I tried and it didn't do much. I assume this is because it's choline and your body regulates how much is converted to acetycholine in small ammounts.

CDP choline and Alpha GPC are already forms of acetylcholine, these work much better. because this is what your body requires for arousal. took me a week dosing 250mg CDP choline three times a day to start noticing effects.

Give us a report on either that or galantamine, I haven't tried it myself and I'm eager to know thanks.

Edited by perplex, 04 December 2013 - 08:40 AM.

[Braziliandude]

Finasteride isnt a medicine that messes up with the CNS (bullshit)...and now I have all of the sexual side effects plus other side effects that arent even listes, like shrunken balls and penis lack os sensitivity...you name it. God what a fucking nightmare, thank god for cerebrolysin ! If it wasnt for that I would probably kill myself.

[Coffeee]

You see here is the important part:

Choline bitrate or lecithin won't really yield results for this matter. I tried and it didn't do much. I assume this is because it's choline and your body regulates how much is converted to acetycholine in small ammounts.

CDP choline and Alpha GPC are already forms of acetylcholine, these work much better. because this is what your body requires for arousal. took me a week dosing 250mg CDP choline three times a day to start noticing effects.

Give us a report on either that or galantamine, I haven't tried it myself and I'm eager to know thanks.

perplex, do u still have to keep taking the cdp choline or have you weaned off it and are back to normal, buying the galantamine today will let u know.

[perplex]

Good Question,

I can't say because as soon as I got better I tried Piracetam and the exact same thing happened. I'm getting better as I supp CDP-choline once again and as then soon I hope I can wean off it once my acetylcholine levels stabalize

Yeah, Please let me know how it goes

Edited by perplex, 04 December 2013 - 05:41 PM.

[Coffeee]

Good Question,

I can't say because as soon as I got better I tried Piracetam and the exact same thing happened. I'm getting better as I supp CDP-choline once again and as then soon I hope I can wean off it once my acetylcholine levels stabalize

Yeah, Please let me know how it goes

Im waiting for it to come in the mail,

i bought cdp choline taking it everyday, im not seeing the complete return of libido, although it seems that my morning wood is about 5-7 % percent stronger, still nothing like it was before i took piracetam or this pramiracetam.

Im wondering if it was contaminated with heavy metals, im going to buy a testing kit and drop them in water and test them out.