136 replies to this topic

[eon]

I'd have to look into NSI-189, not sure what it's all about. I kept hearing about it but never looked into it. Did you combine it sometimes with 7,8-DHF?

[Ark]

Bulk sources?

[eon]

no one has it bulk yet. not that I could find.

[Baten]

Bluebrainboost carries this, for the record. Have 1g to play with, will update once I do.

[tolerant]

Hey guys,

 

I tried to take a dose of 7,8-DHF sublingual, but found that it just didn't absorb. Instead it just stuck to my teeth and gums. So I took a dose insufflated after reading this thread. Anyone else take theirs insufflated?

 

Kind regards,

 

tolerant

Edited by tolerant, 07 November 2015 - 10:43 PM.

[eon]

any updates?

 

what's the effect insufflated?

 

Bluebrainboost carries this, for the record. Have 1g to play with, will update once I do.

 

 

Hey guys,

 

I tried to take a dose of 7,8-DHF sublingual, but found that it just didn't absorb. Instead it just stuck to my teeth and gums. So I took a dose insufflated after reading this thread. Anyone else take theirs insufflated?

 

Kind regards,

 

tolerant

 

[TheLovedOne]

I tried the 7,8-DHF maybe 6 months ago; I bought it from Antaeus labs, opened a capsule and took a small amount of the powder under my tongue. I was very severely depressed at the time and my brain felt like it was physically hurting.

Shortly after I took the powder I felt a warm feeling in my chest and a most definite psychiatric analgesia. It was a great relief and lasted for hours.

The next day, when I took the powder though, I felt only a tight and very unpleasant feeling feeling in my chest that lasted for at least an hour. A few times since I have tried again but only ever experienced same.

I would be most interested to know what is going on to cause the chest sensation if anyone has any idea(?) I saw at least one other person has reported getting a feeling in their chest.

[The Brain]

Have you tried snorting it as mentioned above

[tolerant]

Sorry for no updates on 7,8-DHF. I think I've taken it for five days now, and while I've been feeling much better than usual in terms of mood, I have also developed insomnia after the first dose. And I'm not sure how the two are linked. Not getting enough sleep improves depression for 60% of people from memory -- it's a well-known fact. I am hoping though it is being caused by being overexcited at having more drive and energy. So the anxiety and racing thoughts are still there, but it's more of a rational anxiety rather than irrational anxiety and OCD. However, I can feel that my mood is beginning to dwindle a little and OCD return under the weight of the insomnia. I cut my dose from 30 mg insufflated to 15 mg insufflated yesterday. Still getting some of it come down to the roof of my mouth. I'm also trying a few other things simultaneously which makes drawing conclusions difficult. I need to let things settle down beofre I report anything concrete.

[The Brain]

Ok thanks, good luck with finding what helps.

[Viridarius]

I've heard most 7,8-dif on the market was actually trihydroxyphenylfuck.

[Soma]

This was originally billed as something like a 2 day cure for depression in a post here on longecity but the experience reports do not sound terribly impressive. In fact, they have the ring of placebo effect to me. It appears that this compound just doesn't pan out which is a shame. Unfortunately, this seems to be the norm- the actual effects of these miraculous psychotropic compounds never quite live up to the speculative hype generated about them.

If there are any positive recent reports, I'd love to hear them.

Edited by Soma, 04 February 2016 - 11:19 AM.

[normalizing]

yes, i would like update on this as it seems to be forgotten at this point. any recent reports and especially important for me, any sources?? its very difficult to find that one online and some vendors who used to carry it, no longer do :(

[BioHacker=Life]

yes, i would like update on this as it seems to be forgotten at this point. any recent reports and especially important for me, any sources?? its very difficult to find that one online and some vendors who used to carry it, no longer do :(

 

Several vendors sell it.

 

Antaeus Labs, Bluebrainboost, Cognitive Nutrition, Syntharise.

 

I've used all of them except Syntharise.

Edited by BioHacker=Life, 14 December 2017 - 08:35 AM.

[normalizing]

i ordered from bluebrainboost while ago now but i have no tracking number or any clue when its coming

[gamesguru]

i have no tracking number or any clue when its coming

 

sounds like a typical product pusher

 

and not to be a party pooper, but i think a diet rich in polyphenols and flavonoids would be better long-term.  you might see quick gains from such a potent TrkB agonist, but we saw pretty much the same concerns with dihexa and HGF.  it's like paddling across a lake, you end up chasing the dragon.  you might think you're paddling twice as fast but that's when you just break you oar man, and then youre over the hill

[BioHacker=Life]

i ordered from bluebrainboost while ago now but i have no tracking number or any clue when its coming

 

It's in stock right now.

[normalizing]

 

i have no tracking number or any clue when its coming

 

sounds like a typical product pusher

 

and not to be a party pooper, but i think a diet rich in polyphenols and flavonoids would be better long-term.  you might see quick gains from such a potent TrkB agonist, but we saw pretty much the same concerns with dihexa and HGF.  it's like paddling across a lake, you end up chasing the dragon.  you might think you're paddling twice as fast but that's when you just break you oar man, and then youre over the hill

 

 

dihexa and HGF? we? i havent seen anything about that. what are you saying? ive lost track of dihexa long time ago i dont keep up with current research on that one. anyway you seem to always slam those research chems, but you are obviously a very devoted follower to any new updates that happen when it comes to them, interestingly enough

Edited by hazy, 15 December 2017 - 04:43 AM.

[gamesguru]

well it wasn't fully decided, but an alarming number of individuals had complained of tolerance

 

and others raised concerns of how such an unprovoked boost in neurotrophin activity (without a complimentary boost in apoptotic activity) could lend itself to the division of cancerous neurons

 

i would just be cautious with this one, anything that's 10 million times as potent as its natural counterpart, you gotta show that some respect

[airplanepeanuts]

well it wasn't fully decided, but an alarming number of individuals had complained of tolerance

 

and others raised concerns of how such an unprovoked boost in neurotrophin activity (without a complimentary boost in apoptotic activity) could lend itself to the division of cancerous neurons

 

i would just be cautious with this one, anything that's 10 million times as potent as its natural counterpart, you gotta show that some respect

According to the wikipedia page 7,9 dihydroxyflavone is natural. 

[gamesguru]

 

7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves.

 

the plant's name starts with "god".  hemlock, morphine and the ergot alkaoids are natural too, doesn't mean you should go taking them tho

[airplanepeanuts]

You are right. But that just goes to show that it's not a valid point to say stick to the natural stuff. 

[gamesguru]

You are right. But that just goes to show that it's not a valid point to say stick to the natural stuff. 

then go pump yourself full of pills man, see if i'm right

 

outright death is one thing, messing with your genetics in subtle ways is quite another.  a lot of these chemicals in plants were natural defenses that we evolved alongside.  man-made chemicals are relative unknowns to the body

 

and when it comes to things that are more well-established, it really goes without saying that a cup of tea will be less effective but more safe than a mysterious, new substance X

[normalizing]

yeah but we gotta get with the program eventually. we evolved with plants, but should that be forever in the future? we should move away eventually and explore new territory. its humankind's evolution, just like people got tired of studying plants and decided to explore mars soon. why would you still be exploring plants at this point? rather go to the moon, mars and next any other planet. your point is not valid to stick to the same old because its proven safe sorry

[gamesguru]

we evolved with plants, but should that be forever in the future? we should move away eventually and explore new territory.

 

keyword: eventually.  you don't walk across a river until the ice has frozen shut

[BioHacker=Life]

 

 

7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves.

 

the plant's name starts with "god".  hemlock, morphine and the ergot alkaoids are natural too, doesn't mean you should go taking them tho

 

 

Tridax procumbens a natural source of 7,8 DHF has been used for centuries traditionally in Indian without any reported serious issues.

 

Judging a chemical by it's name is utterly ridiculous and irrational. If you were in severe pain you probably should take morphine. And if you were at risk for stroke, head injury, certain surgeries, drowning, tbi, etc you would want to be taking Hydergine daily.

[normalizing]

i just got my 1gram of bluebrainboost dihydroxyflavone and im not sure at what amount to take for any effect yet. at just 1gram not sure i can take this for more than few days and let alone the price is killing me, its too expensive.

[gamesguru]

Tridax procumbens a natural source of 7,8 DHF has been used for centuries traditionally in Indian without any reported serious issues.

 

Judging a chemical by it's name is utterly ridiculous and irrational. If you were in severe pain you probably should take morphine. And if you were at risk for stroke, head injury, certain surgeries, drowning, tbi, etc you would want to be taking Hydergine daily.

 

it's been concentrated many times over to an unnatural level, and procured specifically for it's BDNF-mimicking effects.

 

and then i would ask, from which ailment must you be afflicted to justify the use of 7,8- dihydroxyflavone?  dementia.. depression?  are there not better, more tested choices on the market?

[normalizing]

ive no idea how much to take, but last night i sipped some of it in my beer and drank it. i never felt anything really except of course the high from alcohol. im still figuring out how to use it and how much mg do i need. i still hate how expensive it is and how little to use is there

[Mind_Paralysis]

ive no idea how much to take, but last night i sipped some of it in my beer and drank it. i never felt anything really except of course the high from alcohol. im still figuring out how to use it and how much mg do i need. i still hate how expensive it is and how little to use is there

 

Using alcohol with a substance, which, at least in this extremely purified and potent form, is badly studied in humans, is a very irresponsible and possibly dangerous thing to do.

 

Don't drink and use research-chemicals for god's sake!

 

I'd love to go on a tirade about this, but you're probably already aware of how NO ONE, under any circumstances, should ever use Alcohol for anything, except possibly as a cleaning agent. That's all it's ever good for - it really should be illegal, in ALL jurisdictions.
 

As you're probably aware, anyone with DP/DR like or depressive symptoms should especially stay away from it, since it's known to induce such states, with prolonged use.

Edited by Stinkorninjor, 18 December 2017 - 09:53 AM.