...my attention deficit does not seem to have abated the slightest bit, and I've been sitting here trying to read this one-page article for the full hour since ingesting the substance. Two or three words read, and then I'm off to make coffee/clean the tub/ paint my nails etc... Business as usual. I do hope that over time I experience some subjectively measureable effect. I'll try stacking it with Phenylpiracetam soon.
Based only on the experiences of myself and others, but not on any objective research, high-dose picamilon and fasoracetam each seem to help with focus and attention. I get such extreme focus on fasoracetam that it's problematic because I'll just zone in on something and get stuck there for hours. I don't like that! But for you, maybe it would be a good thing. As for picamilon, I've been told by a couple other people that it helps them to stay on task with good focused mental energy and clarity. The dosage would be in the 500 to 1000 mg range.
I've combined PRL-8-53 with both picamilon and fasoracetam without noticing any particular problems that weren't present with faso. by itself, and I'm not aware of any risk in doing this as long as dosages of faso and prl are both kept reasonably low. I personally think it's unwise to take megadoses of such substances, but picamilon is very safe.
I'd hate to hijack this PRL-experience thread and delve into Fasoracetam territory, but you've got me intrigued. I'm quite unenlightened about Faso since it's a relatively new substrate in terms of actual human use, and the PubMed research is sparse. However, I'm interested enough in its purported benefits to click the BUY button on Powder City and order some of this compound tonight. As a disclaimer, I've not been clinically diagnosed with Attention Deficit so when I refer to myself as having the disorder it's pure unabashed self-diagnosis, assisted by research, and personal clinical experience diagnosing psychiatric disorders; in other words, take my diagnosis with a grain of salt.
Today is my fourth day on PRL and I'm still quite ambivalent about the substance. My specific reason for taking PRL was to improve working memory but I cannot say with any degree of certainty what, if any, effect it has had on that aspect of my memory. I conducted some memory tests specifically aimed at assessing working memory on Cambridge Brain Sciences.com today and, in typical fashion, I left the site feeling dumber than my dumb cousin's dumb cousin. I was consistently inconsistent in my scoring, with scores vacillating wildly from one session to the next on the same test metric! It's almost as if there were separate entities taking the test from one administration to the next. Because my test results are so fragmented I'm on the hunt for other metrics I can use to test my standing as I trial this substance, although it's a quite difficult task since there will inevitably be confounding variables that account for any perceived improvements. Further, I've already bastardized the process since I was unwilling to restrain myself from isolating PRL and trialing it independent of any other nootropic. I began adding some of my old standby's into the mix as of yesterday (piracetam, phenylpiracetam) and even newly began on L-theanine to add insult to injury!
Back to the Fasoracetam: do you know whether its mechanism of action is, at least partly, due to influence on cAMP, a la Guanfacine, or if it works more in line with the stimulant treatments i.e. adderall and its ilk?
I know that high levels of cAMP has been implicated in ADHD so I'm wondering if, similar to Guanfacine, Faso lowers or blocks cyclic AMP since the newer genre of ADD treatments tend toward regulating cAMP vs. the old-school stimulant mode of treatment.
If cAMP modulation is indeed implicated in FASO's mechanism of action I do, however, worry that while my prefrontal cortex memory system might be enhanced (if indeed faso improves working memory, and does so via blocking cAMP), my other memory systems might be negatively impacted, since other parts of the brain depend on *high* cAMP levels. I certainly don't want to be able to recall what object is hidden behind the blue door, but yet be unable to remember my teenage sweetheart or my childhood pet!
I will search the forums and subscribe to one (or several) Fasoracetam threads so that I can catch up, and keep up, with the conversation...
Edited by blueenigma, 04 February 2015 - 03:16 AM.
