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[LexLux]

I just used my pill machine to combine my trans-reveratrol supplement from life extension (contains quercetin) with turmeric, black pepper, rhodiola, ashwagandha and creatine. Each new capsule contains a smaller dose of each supplement than what was present in their original respective capsules. So this means smaller doses with every meal and I can take advantage of the oil in food to help with absorbtion.

Why?-
There could be benefits of taking resveratrol with the curcumin since they have been observed to act synergistically in:

• suppressing immune response where a faulty immune response plays a pathogenic role in a wide spectrum of inflammatory diseases and;
  
  • http://www.ncbi.nlm....les/PMC1810449/
• anti-cancer
  
  • http://www.ncbi.nlm....pubmed/23446753
  • http://www.tandfonli...62#.UwYNFc4U2W8

The black pepper should increase the bio-availability of:

• resveratrol and;
  
  • http://www.ncbi.nlm....pubmed/21714124
• curcumin
  
  • http://www.sciencedi...00689931201606X

Finally, has anyone tried heat-stabilising turmeric/curcumin (other than with cooking) to increase bioavailability? This study seems support it:

• http://online.lieber...89/adt.2007.064

I was thinking of putting some in a pan and heating it in the oven until the water boils away. Thoughts?

Why is this not a good idea? -
I do question if there might be a downside considering that Resveratrol, Curcumin and Quercetin inhibit p450, could this be doing more harm than good? I dont take any persciptions, but I am not sure about the nootropics.

http://www.ncbi.nlm....pubmed/20027150

However I did find this study:

Piperine and Quercetin Enhances Antioxidant and Hepatoprotective effect of Curcumin in Paracetamol Induced Oxidative Stress:

http://web.b.ebscoho...spLJwGA==&crl=c
Any feedback would be appreciated.

Edited by LexLux, 20 February 2014 - 07:27 AM.