#31
Posted 11 March 2014 - 04:09 PM
#32
Posted 11 March 2014 - 04:10 PM
Edited by addx, 11 March 2014 - 04:12 PM.
#33
Posted 11 March 2014 - 04:27 PM
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#34
Posted 11 March 2014 - 04:43 PM
socialpiranha wrote in this thread that he contacted him(not me) just now, here's the post:
I got an email from a guy claiming to be the guy supplying it for david pearce, he understands my skepticism so i think he's going to send me a sample for free. Anyway h'es selling it in grams i dunno if he would sell in smaller amounts or not but if he will we could get like 250mg or more.The guy only has a few posts but he's been on here since 2008 so i dunno how legit he is i guess i'll have to wait to see if he sends a sample or not.
I also have this mail from Dave saying that JDTic.is guy is his source also from back when JDTic.is was up.
From: David Pearce [ mailto:dave@hedweb.com] On Behalf Of David Pearce
Sent: Tuesday, July 16, 2013 11:48 PM
To: xxxxxxxx
Subject: RE: feellow psycsychonaut, please respond
Hi xxxxxxx
Apologies for the delay.
Yes, that is my source = - it's legiit!
Davbe
At 18:58 16/07/2013, you wrote:
Prodding again J Pleeeeease J
Or do you know if jdtic that is available through www.jdtic.is is legit as well?
LP
So, socialpiranhas guy should be the JDTic.is guy is what I wanted to say. And he should recognize his pricelist And he should also have my mails
Edited by addx, 11 March 2014 - 04:45 PM.
#35
Posted 11 March 2014 - 07:01 PM
socialpiranha,
benthamite has replied to a personal conversation entitled "JDTic".
benthamite said:
======================================================================
Great. My friend will email you a few mg of JDTic within the coming week to the address you provided. It will come in a standard business envelope.
======================================================================
PLEASE DO NOT REPLY DIRECTLY TO THIS EMAIL!
You can reply to this personal conversation by following the link below:
Edited by socialpiranha, 11 March 2014 - 07:17 PM.
#36
Posted 11 March 2014 - 08:25 PM
#37
Posted 11 March 2014 - 09:33 PM
#38
Posted 11 March 2014 - 09:50 PM
Also of note: all of us seem to count on kappa upregulation being our "woe" and some of us went to great lengths to explain kappa upregulation being a key mediator of, in short, "bad stuff". Still, that doesn't have to true and not all of us might reap benefits from kappa antagonism.
Well, I know what kappa antagonism feels like and it really does neutralise the effects of years of trauma. I suppose that might be more specifically kappa mediated than some other conditions but the benefits are real. Edit: I'll volunteer too.
I wonder if the stereochemistry is the issue with the current batch. Going from mg to grams is suspicious. How much easier could it get to synthesize?
Edited by celebes, 11 March 2014 - 09:54 PM.
#39
Posted 11 March 2014 - 10:10 PM
So what is the minimum cost of ordering?
Edited by Jbac, 11 March 2014 - 10:16 PM.
#40
Posted 11 March 2014 - 10:47 PM
#41
Posted 11 March 2014 - 11:08 PM
#42
Posted 12 March 2014 - 12:06 AM
#43
Posted 12 March 2014 - 12:21 AM
#44
Posted 12 March 2014 - 12:38 AM
#45
Posted 13 March 2014 - 01:02 PM
On a side note: Is it not possible to get a refund from MedChemExpress?
#46
Posted 13 March 2014 - 07:40 PM
#47
Posted 14 March 2014 - 02:37 PM
However; in the event that indeed it is what we hope it to be, and we continue to buy it: Bitcoin is still an irreversible currency. Who's to say he doesn't just run off with the ~2-4 BTC we pay him? I would strongly suggest using an escrow service, or have someone provide it for us (maybe Pearce?). Simple services like MitM.io exist for this purpose; but I'm not sure how the resolution center would sort out any problems with suspected fake chemicals.. Not too sure they'd be fond of that, or if it's even covered in their terms.
But simply sending 2-4BTC to "that guy" is a big leap of faith.
#48
Posted 14 March 2014 - 03:58 PM
#49
Posted 14 March 2014 - 11:28 PM
Id get the sample of this batch too, I forgot that money, but didnt forget hope
#50
Posted 16 March 2014 - 06:08 PM
Edited by formergenius, 16 March 2014 - 06:08 PM.
#52
Posted 18 March 2014 - 11:19 PM
I was just thinking: if JDTic is a KOR antagonist, and Dynorphin is an NMDAR antagonist, wouldn't JDTic increase net NMDAR antagonism by diverting more Dynorphin to NMDARs, thus resulting in dissociative effects?
it is possible yup but i think the free dynorphin would be assimilated through homeostatic mechanisms before it had a chance to, kappa antagonism is known to have anti dissociative effects so it must not be an issue
#53
Posted 18 March 2014 - 11:24 PM
#54
Posted 18 March 2014 - 11:48 PM
Good point; I also remembered that it attenuates NMDA antagonist induced dissociation, thus probably does not have the effect I described.it is possible yup but i think the free dynorphin would be assimilated through homeostatic mechanisms before it had a chance to, kappa antagonism is known to have anti dissociative effects so it must not be an issue
I would really appreciate that JbacOK, if the powder is physically stable enough to work with, if it's active in microgram doses, and if the sample is big enough, I'll try to divide it and send to anyone in this thread who wants to try it.
Edited by formergenius, 18 March 2014 - 11:48 PM.
#55
Posted 19 March 2014 - 04:12 AM
#56
Posted 23 March 2014 - 10:51 AM
If possible I like to try too.
#57
Posted 23 March 2014 - 11:24 AM
#58
Posted 23 March 2014 - 11:28 PM
Just wanted to post about Arodyn, which is a KOR antagonist as well, in case you guys were interested. Not too much to find about it, but I found it interesting that arodyn.com is registered to BLTC.
Also, I thought you guys might be interested in a little chaotic post I wrote about CILTEP and why not to take it. Would like to hear your thoughts on that, if you have any. Obviously decreasing CREB wouldn't be too great either, but increasing it doesn't seem beneficial to one looking to decrease Dynorphin/KOR activity.
#59
Posted 25 March 2014 - 02:13 PM
Haven't yet read through it, but I imagined you all would be interested in it, seeing as I myself haven't been able to find how Dynorphin is biosynthesized. Yet to read through it though.
I thought if this doesn't work out, inhibiting biosynthesis of Dynorphin may be interesting.
#60
Posted 25 March 2014 - 11:18 PM
Sample should arrive this week
Actually I don't know how long it takes for an envelope to get from Nova Scotia to the U.S., it might be a while.
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