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Nootropics that improve sleep quality.

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#1 Nobility

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Posted 04 March 2014 - 10:07 PM


Hi folks,

Does anyone know of which Nootropics to take before bed/sleep that can help improve sleep's quality.
From my understanding of watching and reading from doctors. Such as, in your sleep your brain remembers everything again (goes through everything) and restores/heals itself and the body.

Now, are there any Nootropics that help the brain enter the stages, etc. or anything that helps the brain during sleep resulting in better sleep quality.

thank you.

I will send a donation and some +rep to people who provide good sources which I will buy.thank you.

#2 deadkenny64

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Posted 05 March 2014 - 09:23 PM

I have had good luck with 5-HTP but only once a week or so. If I take it more than 2 days in a row, I don't get any benefit. It increases the vividness and complexity of my dreams and has even sparked a few lucid dreams. I always wake up feeling refreshed. I use 50mg doses but have read about good results with 100mg also.

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#3 Flex

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Posted 06 March 2014 - 07:19 AM

- Ashwagandha,I would use the Sensoril brand e.g. from Jarrows formula because it seems not to be a strong anticoagulant like tthe KSM-66 or usual extracts

- Bacoopa Monieri ( Bhrami)

- Gotu Kola(Centella Asiatica)

- Magnolia Extract


Ashwagandha has as far as I know the most Nootropic effects and Bacopa and gotu kola are also better afaik than Magnolia in terms of nootropic effects.

But Magnolia is the most sedating compounds followed by Ashwagandha
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#4 Rior

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Posted 06 March 2014 - 07:46 AM

Not your average recommendation...but for the sake of mentioning it, as this is an unrestricted board where people feel open to talk about any substance, GHB is supposed to greatly increase sleep quality. I remember reading that it increases REM sleep, and subsequently increases HGH as well. Of course, it's obviously very addicting and that's a bit of an issue, but occasional use (2-3 times a week, only at night in low doses to sleep) should probably be helpful for sleep without inducing much GABAB downregulation. I've honestly considered it recently for sleep uses, but of course one has to be quite diligent in making sure they don't use it too frequently and don't develop an addiction. There are better substances that may help sleep generally, but GHB has been found to be very directly helpful in not only increasing duration of sleep, but increasing quality of sleep without interrupting the sleep architecture.

Here's one study:

http://www.ncbi.nlm....cles/PMC508244/






#5 silverbear

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Posted 07 March 2014 - 09:18 PM

Taking Ashwaganda (Himalayan brand) and a magnesium supplement from Natural Stacks about an hour before bedtime has produced a really sound and restful sleep for me.

#6 Complexology

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Posted 22 June 2014 - 09:23 AM

Dear friends,
 
I am convinced this article is worth gold to all living entities in the universe who wants improved sleep or want to delete or reduce the suffering from sleep disorders. 
 
1. Study: 
It is wisely adviced to study all the information, do personal research, information retrieval, data gathering (google) and inquire knowledge about these topics before consuming any content, supplements and physical ingredients or practicing any activities related to sleep induction.
 
2. Related study material:
Why sleep improvement? -Sleep benefits: http://healthysleep....nefits-of-sleep
 
3. Validation:
I apply the powerful natural sleep supplements on myself daily since October 2013, this is totally approved by my bodies chemistry. I also know of other individuals and associations acknowledging the benefits from it.
 
4. Motivation:
I myself experienced insomnia in month june till july 2013 (4-6 hours sleep a day), and because of the setback, pain, sleep deprivation, frustrations, and multiple other negative symptoms that impacted my life, I was moved to want to solve the issue for myself and humanity. 
 
5. Powerful natural sleep supplements, for evening and before bed
1. 1 cup of Chamomile tea - plus add honey
2. 400mg Magnesium
3. 200mg Zinc
4. 200mg Calcium
5. 100mg Suntheanine
6. 100mg Potassium to start with and build up to 300mg
7. 15 mg Collagen protein
8. 5mg coconut oil
 
Extra:
Binaural beats 8 hours deep sleep 
 
6. Caution, study before application, wrong application can lead to health problems (Optional)
1. Gaba 500mg first study: 
2. Ornithine 1-5 grams
3. Arginine Growth hormone 1-5 grams
4. L-tryptophan
5. GHB ambien
6. Melatonin
7. Valerian Root
8. Orgasm/Ejaculation/Copulation
9. -- Severe sleep disorder -- go to the doctor and ask for sleeping pills.
 
7. Other practical sleep advice: 
1. Breakfast big meal
2. Dark room
3. Exercise for improved sleep
4. Get enough Vitamin b6, b12, calcium and iron throughout the day
5. For better sleep 90 mins before bed adviced not to use electrical devices
6. Meditation
7. Sleep journal
8. Lavender 
 

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#7 Sciencyst

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Posted 21 December 2014 - 09:29 AM

 

6. Caution, study before application, wrong application can lead to health problems (Optional)
1. Gaba 500mg first study: 
2. Ornithine 1-5 grams
3. Arginine Growth hormone 1-5 grams
4. L-tryptophan
5. GHB ambien
6. Melatonin
7. Valerian Root
8. Orgasm/Ejaculation/Copulation
9. -- Severe sleep disorder -- go to the doctor and ask for sleeping pills.
 
 

 

 

Uhh, never heard of GHB-ambien haha. I'm sure GHB/ambien would help short term but chronic use is really going to rewire one's brain in negative ways.


Edited by katuskoti, 21 December 2014 - 09:29 AM.


#8 crazepharmacist

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Posted 21 December 2014 - 05:20 PM

Delta sleep inducing peptide.

#9 Flex

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Posted 21 December 2014 - 07:43 PM

Dont know whether Lemon Balm was allready mentioned



#10 Mr Matsubayashi

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Posted 22 December 2014 - 07:32 AM

This might sound very oldschool but people always forget the basics and try to solve the problem with bunch of pills. Be wary of Gaba agonist.

 

Don't exercise too close to bed time,

Don't eat a heavy meal meal close to bed time,

Don't consume large amounts of sugar or take stims in the afternoon,

Try to form a consistent sleep wake schedule (Go to sleep when you're tired and try not to miss your bodies signals, wake up no later than your alarm clock, ever!)

Make sure your room is quiet and dark,

Get on top of all the things looming over your head,

Remember that bed time is the best time!

 

Eat a sweet potatoe, take some magnesium supps if you want. Sleep like a panda.

 

If you're suffering from depression or life is getting the better of you I think speaking to someone about what's on your mind will help. :)


Edited by Mr Matsubayashi, 22 December 2014 - 07:42 AM.

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#11 HappyShoe

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Posted 24 December 2014 - 10:19 PM

 

Dear friends,
 
I am convinced this article is worth gold to all living entities in the universe who wants improved sleep or want to delete or reduce the suffering from sleep disorders. 
 
1. Study: 
It is wisely adviced to study all the information, do personal research, information retrieval, data gathering (google) and inquire knowledge about these topics before consuming any content, supplements and physical ingredients or practicing any activities related to sleep induction.
 
2. Related study material:
Why sleep improvement? -Sleep benefits: http://healthysleep....nefits-of-sleep
 
3. Validation:
I apply the powerful natural sleep supplements on myself daily since October 2013, this is totally approved by my bodies chemistry. I also know of other individuals and associations acknowledging the benefits from it.
 
4. Motivation:
I myself experienced insomnia in month june till july 2013 (4-6 hours sleep a day), and because of the setback, pain, sleep deprivation, frustrations, and multiple other negative symptoms that impacted my life, I was moved to want to solve the issue for myself and humanity. 
 
5. Powerful natural sleep supplements, for evening and before bed
1. 1 cup of Chamomile tea - plus add honey
2. 400mg Magnesium
3. 200mg Zinc
4. 200mg Calcium
5. 100mg Suntheanine
6. 100mg Potassium to start with and build up to 300mg
7. 15 mg Collagen protein
8. 5mg coconut oil
 
Extra:
Binaural beats 8 hours deep sleep 
 
6. Caution, study before application, wrong application can lead to health problems (Optional)
1. Gaba 500mg first study: 
2. Ornithine 1-5 grams
3. Arginine Growth hormone 1-5 grams
4. L-tryptophan
5. GHB ambien
6. Melatonin
7. Valerian Root
8. Orgasm/Ejaculation/Copulation
9. -- Severe sleep disorder -- go to the doctor and ask for sleeping pills.
 
7. Other practical sleep advice: 
1. Breakfast big meal
2. Dark room
3. Exercise for improved sleep
4. Get enough Vitamin b6, b12, calcium and iron throughout the day
5. For better sleep 90 mins before bed adviced not to use electrical devices
6. Meditation
7. Sleep journal
8. Lavender 
 

 

Just a note on Iron
Be very careful telling people to get iron.
Some people may haphazardly take iron supplements, not knowing they could be killing their liver/pancreas.
Especially men, who unless vegetarians, definitely get enough every day.(except in very rare instances)
Anyone of Irish/German/English/Scottish/Welsh Ancestry is significantly more likely to have Hemochromatosis, meaning they have to be very careful about iron intake even from dietary sources(particularly Heme iron from red meat).
For pre-menopausal women it's generally a good call to be sure if you're getting enough(a blood test perhaps).
You won't notice symptoms of iron overload until it's close to too late, so don't assume your body will tell you by making you sick or something.
Too much iron deposits in the organs and starts to cause irreversible organ failure. Preferential areas of deposition are the liver and pancreas(causing cirrhosis and diabetes), then the heart and eventually the brain.
At some point it will cause fatigue and bronzing of the skin particularly near the armpits, although your levels have to get pretty high before these will become noticeable, and by then you're already full of iron.

 

Calcium should be taken in the morning with a meal, by itself(it interferes with the absorption of many minerals) best taken concurrently with Vitamin D, and only 200mg at a time. Do not take Vitamin D at night.
Magnesium should be taken on an empty stomach, since a number of things interfere with it's absorption(Oxalates, Phytates, D, Calcium).

More than 200mg supplemental calcium per day is contraindicated in men, since it contributes heavily to the risk of prostate cancer when taken over this amount.

 

More than 1mg melatonin is bad for you, and it should not be taken for more than 7 days in a row. It is best used occasionally for jet lag and major sleep disturbances.
A 200 pound man in his 20's only produces roughly .89 mcg of melatonin a night. Even 1mg is roughly 1000 times that. Messing with hormones can be dangerous.

There is some evidence that too much melatonin can shorten your lifespan significantly. Melatonin during high light exposure can also contribute to cancer.

 

Sleeping pills are bad for you, and disrupt your circadian rhythms.

Suggesting to people to take that much Potassium can be dangerous as well, if you think you need potassium, check with your doctor, some people can have a heart attack from too much at once. Again, this is dangerous advice. Electrolytes need to be kept in balance. Sodium is important in relation to potassium and magnesium, so is drinking enough water.

 

There's also a computer program called "Flux" that helps reduce the blue light in your computer, helping you get ready for bed.
Also consider a sun Alarm, which mimics sunrise and is a lot more gentle, natural way to wake up, instead of harsh noises which stress your body. These bring you slowly out of deeper stages of sleep and have been shown to have significant clinical efficacy in regulating sleep cycles.

Exercise during the day helps by producing adenosine.
Avoid drinking liquids too close to bed(at least 2 hours before) since awareness of your bladder will disturb your sleep
Make sure your room is pitch black, and expose yourself to as little light as possible. If you need something to help you see on the way to the bathroom when u wake up to pee, try to get a dim red spectrum light.
 


Edited by HappyShoe, 24 December 2014 - 10:32 PM.

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#12 multispeedo

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Posted 18 July 2016 - 12:04 AM

 

 

More than 1mg melatonin is bad for you, and it should not be taken for more than 7 days in a row. It is best used occasionally for jet lag and major sleep disturbances.

A 200 pound man in his 20's only produces roughly .89 mcg of melatonin a night. Even 1mg is roughly 1000 times that. Messing with hormones can be dangerous.

There is some evidence that too much melatonin can shorten your lifespan significantly. Melatonin during high light exposure can also contribute to cancer.

 

 

 

Yes and no - it largely depends on how you take your Melatonin. If you take your Melatonin sublingually then you are right, don't go over 1mg. But if you take it as a pill or capsule you need way more than that since most of your Melatonin won't survive the gastric acid before making it into your system.

General rule of thumb: Over 90% of sublingual Melatonin makes it to your system, whereas less than 10% of Melatonin swallowed as pills make it. 

 

Generally speaking 3mg is more than enough. 

 

I always take mine as extended release in the DreamQuick Deep Sleep Modulator which in my personal opinion is by far the best sleep supplement on the market.



#13 Gary R

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Posted 18 July 2016 - 12:06 AM

Kava Kava Extract : http://topextracts.c...iate.php?id=107



#14 temperance brennan

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Posted 18 July 2016 - 12:34 PM

Actually last year I started having problems too. So what do modern people do? They google things. Here's what I found and you can see that there are plenty of ways of fighting problems even if it's an unconventional way.


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#15 PeaceAndProsperity

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Posted 18 July 2016 - 01:09 PM

BCAAs work.



#16 normalizing

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Posted 19 July 2016 - 02:04 AM

any actual negative research into the use of melatonin particularly high doses? i thought long ago it is a potent neurohormone and it should be illegal to be sold so openly in stores, but it seems there are zero reports on any long term use negative effects so, i guess its still debatable?



#17 telight

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Posted 19 July 2016 - 02:41 AM

I can't believe no one has mentioned MK-677. The stuff has an acute nootropic effect and improves sleep quality by increasing beneficial deep sleep and is non-sedative. The only issue is tolerance and the side effect of increased appetite. See attached study.

Attached Files


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#18 PeaceAndProsperity

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Posted 19 July 2016 - 11:20 AM

I can't believe no one has mentioned MK-677. The stuff has an acute nootropic effect and improves sleep quality by increasing beneficial deep sleep and is non-sedative. The only issue is tolerance and the side effect of increased appetite. See attached study.

I used it and my bones, particularly my wrist, did grow slightly.

At that time I couldn't sleep very well due to being constantly overstrained and overexhausted. MK-677 made sleeping heavier, like a growth hormone cycle usually does, and improved very slightly the duration of sleep by extending it, and sometimes it also made it easier to fall asleep, but don't take it to be a miracle cure since it only works if you have very mild sleep issues.



#19 psychejunkie

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Posted 19 July 2016 - 12:26 PM

Wow! nobody had mentioned Vitamin B1!?

I used to take VitB1 300 mg (sublingual) whenever overthinking caused falling sleep difficult, I guess most people have the same problem.

It also improves sleeping quality, I felt rested and refresh in morning.

 

although both statements above are my own experience & conclusion.



#20 normalizing

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Posted 19 July 2016 - 06:03 PM

thiamine made you sleep like a baby? wow thiamine is energy boosting b vitamin, i cannot sleep on it. you are just weird



#21 treonsverdery

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Posted 22 July 2016 - 07:45 PM

Magnesium threonate is published as strongly increasing the long term memory of rats (or possibly mice) http://www.lifeexten...eration/page-01

 

as a magnesium source it might also cause drowsiness


Edited by treonsverdery, 22 July 2016 - 07:47 PM.


#22 gamesguru

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Posted 22 July 2016 - 11:05 PM

galantamine, spinosin, and tetrandrine. they all increase predominately REM sleep, and may induce vivid dreaming. (however, it's not clear if the increased REM time is compensatory, and is the body responding to more inefficient sleep... or just longer sleep at the same level of restfulness and efficiency)


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#23 Tomaski

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Posted 23 July 2016 - 07:46 PM

300mg Magnesium
500mg GABA
450mg Taurine
200mg L-theanine
100mg Holy Basil Leaf extract
 

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#24 normalizing

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Posted 23 July 2016 - 07:49 PM

^ this is what confuses me, how does one tell if they had naturally real good deep sleep or was it just an illusion. sometimes a person can sleep just 4 hours and feel rested, other times it takes 8 hours to feel rested, but it can go opposite direction too! without some machinery wired to your head to check on restfulness rate, i suppose sleep and dreaming is an illusion


galantamine, spinosin, and tetrandrine. they all increase predominately REM sleep, and may induce vivid dreaming. (however, it's not clear if the increased REM time is compensatory, and is the body responding to more inefficient sleep... or just longer sleep at the same level of restfulness and efficiency)

 



#25 Mind

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Posted 26 July 2024 - 06:02 PM

Just another good write up and video about how the FDA and US government conducted a largely unscientific smear campaign about GHB.



#26 Daniel Cooper

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Posted 31 July 2024 - 06:18 PM

Just another good write up and video about how the FDA and US government conducted a largely unscientific smear campaign about GHB.

 

 

For all the negative press on GHB it looks like it was a safer more effective alternatives to benzos and z-drugs for sleep.

 

I really wish the FDA didn't seem to be so intent on taking relatively safe and cheap alternatives off the market. But such are the consequences of regulatory capture.



#27 Galaxyshock

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Posted 01 August 2024 - 04:56 AM

GHB for sleep is like Heroin for pain - not quite but you get the idea: bad news in the long term.


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#28 gamesguru

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Posted 01 August 2024 - 09:16 PM

I tend to agree. I'm not an expert in GHB, but saying something is safer or more effective than benzos (or derivative RCs) seems to be setting the bar low.
 
Why wouldn't you use magnesium, which is proven safe and effective? Or tryptophan, which converts centrally to serotonin and melatonin?
 
As an adult with now treated ADHD, I'm not that susceptible to addiction anymore. But even so, GHB, Phenibut, or Trazodone would not be my first choices. They have their use cases, sure, and authority figures may have exaggerated their risks, but I wouldn't promote them as a first-line therapy for chronic insomnia.


#29 Daniel Cooper

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Posted 05 August 2024 - 02:38 PM

GHB for sleep is like Heroin for pain - not quite but you get the idea: bad news in the long term.

 

And benzos aren't?


 

I tend to agree. I'm not an expert in GHB, but saying something is safer or more effective than benzos (or derivative RCs) seems to be setting the bar low.
 

 

 

That is quite true.
 



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#30 Daniel Cooper

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Posted 05 August 2024 - 02:42 PM

Consider that the FDA banned GHB (which had previously been sold as a supplement) ostensibly because it was being used as a "date rape drug". 

 

But of course, the most popular "date rape drug" on the planet has always been good ol' ethanol. Its use for this sort of thing must have outstripped GHB by a thousand to one. Likely more.

 







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