http://www.tribune24...ageing-process/
Has anyone heard about this man before (in the context of stem cell research)?
Edited by Iporuru, 07 March 2014 - 12:46 PM.
Posted 07 March 2014 - 12:37 PM
Edited by Iporuru, 07 March 2014 - 12:46 PM.
Posted 07 March 2014 - 12:55 PM
BILLIONAIRE fashion designer and Bahamas resident Peter Nygard says he is getting younger - after he reversed the ageing process using stem cells.
Posted 07 March 2014 - 07:25 PM
Posted 08 March 2014 - 02:47 AM
Posted 08 March 2014 - 04:54 AM
Edited by Brett Black, 08 March 2014 - 04:56 AM.
Posted 08 March 2014 - 01:37 PM
(For those interested, there are some "before and after" images in the video just after 8:00.)
Posted 09 March 2014 - 03:55 AM
Posted 09 March 2014 - 04:02 AM
(For those interested, there are some "before and after" images in the video just after 8:00.)
Hard to say if the stem cells are responsible. It just looks like he got fit.
Posted 09 March 2014 - 06:14 AM
Posted 09 March 2014 - 12:51 PM
If someone can lift out the before and after images, that would be great.
Posted 09 March 2014 - 08:34 PM
Posted 10 March 2014 - 02:29 AM
Posted 27 October 2014 - 02:46 AM
Absolutely fascinating. That video was really cringeworthy and the product of a insanely huge ego. But, I appreciate that there are billionaires willing to throw caution to the wind and go all-in on this kind of thing.
Posted 06 November 2014 - 01:18 PM
This website appears to be for Nygard Biotech, which looks like it's under development in order to support his SCNT business model. At the moment, the only scientifically established capability of SCNT cell injections is that they enhance one's marketing prowess. This is rather unfortunate, because it casts a pseudoscientific pallor on his uncontrolled but potentially breakthrough self-experimentation and the startup therapy center behind it. But at least, despite the pleuripotency, Nygard has survived more than 4 years with no obvious sign of cancer and at least outward evidence of excellent health for his age. (This is highly significant in itself, especially at his age, and considering the reports of teratomas with other pleuripotent therapies. All in all, it just skews the likely clinical significance in the positive direction.) And just because it's a pseudoscientific Edisonian endeavor doesn't mean it's false; after all, quality scientific "proof" really just comes down to the relative narrowness of various statistical distributions.
It's encouraging that this thread suggests that SCNT may be the most promising means by which to accomplish tissue rejuvenation, in the sense of avoiding erroneous DNA methylation which one's "normal" cells have accrued over time.
It seems that the next step in SCNT would be error correction: Instead of just injecting one's chromosomes into a denucleated donor cell, why not fully sequence one's genome first, using statistics to identify and correct erroneous nucleotides (and perhaps undesirable epigenetic methylations as well), then use a PCR "DNA printer" to manufacture an effectively embryonic copy, which only then would be inserted into the donor cell? I know PCR is a very slow process, so perhaps many parallel machines or some better printing technology would be required for practical applications. But I don't see any fundamental technological barriers to doing so.
Posted 09 November 2014 - 03:15 PM
Absolutely fascinating. That video was really cringeworthy and the product of a insanely huge ego. But, I appreciate that there are billionaires willing to throw caution to the wind and go all-in on this kind of thing.
More on the possible "insanely huge ego": http://www.forbes.co...-to-no-one.html
Posted 23 January 2015 - 08:15 PM
Nygard Biotech's site confirmed as of 12/29/2014 that the $100M facility will indeed be built in 2015. In the interim, the website has introduced a convenient stem cell news feed, which actually involves some news of failures and isn't all sunshine BS. (I suspect they just hooked up an RSS feed from Science Daily etc. to improve their stem cell search ranking.) While Nygard's personal story would great material for People magazine, the important point here is that the general public is soon to have access to SCNT. And if his history in the fashion business is any clue, it's likely to be moderately priced.
Posted 02 May 2015 - 11:52 PM
That video is bananas. Seriously. It was made by him, but still makes him look like a complete nutjob.
That said, just because he's a guy who doesn't have a good grasp on how he comes across, doesn't mean that this all might do some good. He's put a lot of money into "convincing" Bahamas to set up the right legal framework and is now apparently willing to spend billions on research. The question is whether there are enough good researchers in the world who will consider the benefits of ample funding and freedom outweighing the downside of signing up with an organization with a "nutty" reputation rather than a more prestigious university, government, or mainstream biotech company.
Edited by jakeb, 02 May 2015 - 11:52 PM.
Posted 08 May 2015 - 12:24 AM
despite the pleuripotency, Nygard has survived more than 4 years with no obvious sign of cancer
I can't imagine they would have injected him with real, live SCNT-ESC. You have to just wave these cells in the general direction of a matched animal, and it gets a giant tumor. They're unbelievably infectious. Thankfully, anyone with the skill to actually handle these kinds of cells and keep them undifferentiated knows that. They wouldn't be up for it. The intention of SCNT research is to figure out later how to make them into a differentiated product that has known therapeutic value, such as blood or bone marrow, or replacement organs. But nobody has that part down yet.
So when they're injecting him with "stem cells", those are almost certainly an adult / mesenchymal / adipocyte preparation that does not engraft permanently, is nowadays well known to be inefficacious, and would have been called a "plain old cell" 10 years ago. (Before "scientists" figured out that by re-naming random other cells into "stem cells" they can fool billionaires and governments into funding them.)
But that's OK. You win some, you lose some. It appears that he did figure the SCNT thing out, and that deserves praise. It could have been done 10 years earlier. None of the old guard wanna-be immortality billionaires could fathom it's worthwhile. This is no accident. It would be too unlikely to find it by accident. It's more likely that Nygard is capable of original technical thought. That's incredibly good news ;-P
Posted 08 May 2015 - 04:27 PM
" But nobody has that part down yet. "
I'm no specialist in this field, but I saw this from Salk Institute, is this pushing forward?
Scientists stumble across unknown stem-cell type
http://www.nature.co...ll-type-1.17496
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